| Not Yet Recruiting | Effect of Propionic Acid Supplementation on Endothelial Function NCT05135702 | Medical College of Wisconsin | N/A |
| Not Yet Recruiting | Therapeutic Strategies to Reduce Endothelial Ischemia-reperfusion Injury NCT06825143 | Gary Van Guilder | EARLY_Phase 1 |
| Not Yet Recruiting | Role of Endothelial Dysfunction on Exercise Pressor Reflex in Type 2 Diabetes NCT07228208 | Medical College of Wisconsin | N/A |
| Not Yet Recruiting | Associations Between Dietary Patterns, LDL Aggregation, and Cardiometabolic Health: A Cross-sectional Analysis NCT07474233 | Liverpool John Moores University | — |
| Recruiting | TRIal of STatin Therapy Effect on Androgen Status and Erectile functioN in Men NCT07460960 | Lomonosov Moscow State University Medical Research and Educational Center | Phase 2 |
| Recruiting | Effect of a Daily Supplement on Plasma PAI-1 Levels NCT07469475 | University of California, Los Angeles | Phase 1 / Phase 2 |
| Recruiting | TB-500 (Thymosin Beta 4 17-23 Fragment) for Cardiovascular Biomarkers in Stable ASCVD NCT07487363 | Hudson Biotech | Phase 1 / Phase 2 |
| Not Yet Recruiting | Nailfold Capillaroscopy and Endothelial Biomarkers in Healthcare Workers Exposed to Chronic Low-Dose Ionizing NCT07363187 | Istanbul Training and Research Hospital | — |
| Recruiting | Perioperative Outcomes After Neoadjuvant Therapy in Colorectal Cancer NCT07422974 | Osijek University Hospital | — |
| Withdrawn | Determining the Association of Microvascular Disease as Assessed by PET and Graft Injury by Donor Derived Cell NCT05756088 | Yale University | — |
| Completed | Impact of Garlic on the Clinical Outcome in Chronic Hemodialysis Patients NCT07461012 | Ain Shams University | N/A |
| Recruiting | NightWare and Cardiovascular Health in Veterans With PTSD NCT06419959 | VA Office of Research and Development | N/A |
| Recruiting | EndoPAT Device for Endothelial Dysfunction in ED NCT06720597 | University of California, Irvine | N/A |
| Recruiting | Endothelial Dysfunction After SCI NCT07227727 | Craig Hospital | — |
| Recruiting | Testosterone Deficiency and Endothelial Dysfunction After Spinal Cord Injury NCT07227740 | Craig Hospital | — |
| Not Yet Recruiting | NightWare and Cardiovascular Health in Women With PTSD NCT07021014 | University of Colorado, Denver | N/A |
| Completed | The Predictive Value of Modified EASIX Score for Determining Erectile Dysfunction Severity NCT07274982 | Ataturk University | — |
| Completed | Periodontal Pathogens and Atherom Plaque The Number of Mitochondrial DNA Copies NCT07165054 | Istanbul Saglik Bilimleri University | — |
| Recruiting | ACEs, SIRT1, and Premature Vascular Aging in Humans NCT07073352 | Nathaniel Jenkins | N/A |
| Completed | Investigation of the Etiology of Hypertension and Endothelial Damage in Patients With Cytochrome P450 Oxidored NCT06756620 | Ozge Bayrak Demirel | — |
| Not Yet Recruiting | Centella Asiatica in Older Adults NCT06472791 | National University of Natural Medicine | N/A |
| Not Yet Recruiting | Investigation of Novel and Established Therapies in a Human Intravenous Lipopolysaccharide Model of Sepsis NCT06626984 | Belfast Health and Social Care Trust | Phase 1 / Phase 2 |
| Not Yet Recruiting | Effect of Olive Leaf Extracts on Endothelial Dysfunction in Patients With Acute Coronary Syndrome NCT06723002 | University of Monastir | Phase 2 / Phase 3 |
| Recruiting | The Effect of Cytisine Treatment for Smoking Cessation on Cardiovascular Function in Adult Smokers NCT06885970 | University of Athens | — |
| Recruiting | Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM NCT06547619 | Anna Stanhewicz, PhD | EARLY_Phase 1 |
| Recruiting | The Effect of Lipoprotein (a) on Arterial Stiffness, Endothelial Function and Myocardial Deformation NCT07324902 | University of Athens | — |
| Not Yet Recruiting | Physical Activity and Cardiovascular Risk NCT06440369 | University of Franche-Comté | N/A |
| Recruiting | Role of Endothelial Function in SCI CVD Risk NCT06443151 | Craig Hospital | — |
| Not Yet Recruiting | Effects of Anesthesia Technique on Endothelial Function NCT06515028 | Bagcilar Training and Research Hospital | N/A |
| Recruiting | Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use NCT06489249 | University of Iowa | EARLY_Phase 1 |
| Completed | Myoglobin Removal With CytoSorb in Rhabdomyolysis NCT06503289 | Sisli Hamidiye Etfal Training and Research Hospital | — |
| Recruiting | Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation NCT06308952 | Duan Chuanzhi | Phase 4 |
| Not Yet Recruiting | Relative Energy Deficiency in Rowers NCT06452758 | Poznan University of Physical Education | — |
| Recruiting | The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies NCT06454344 | Nathaniel Jenkins | N/A |
| Recruiting | Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Fa NCT06319274 | Pär Johansson | Phase 2 |
| Completed | Onco-Vascular Exer-Study NCT06766903 | Cristian Alvarez | N/A |
| Unknown | Effects of Krill Oil on Intestinal Integrity Markers in Elite Rowers. NCT06271434 | Poznan University of Physical Education | N/A |
| Recruiting | Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal NCT05939934 | University Hospital, Angers | N/A |
| Withdrawn | Safety and Efficacy Trial Using Allogeneic Human Mesenchymal Stem Cells: The SIRONA Trial NCT02587572 | Longeveron Inc. | Phase 2 |
| Withdrawn | Correlation of Serum Gasdermin-D and NLRP-3 Inflammasome Levels With GVHD Biomarkers and Endothelial Damage Ma NCT06200441 | Ugur Arzu Kulu | — |
| Unknown | Optimization of Prime Fluid Strategy to Preserve Microcirculatory Perfusion During Cardiac Surgery With Cardio NCT05647200 | Amsterdam UMC, location VUmc | N/A |
| Suspended | Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes NCT05478707 | University of Virginia | Phase 2 |
| Active Not Recruiting | Fisetin to Improve Vascular Function in Older Adults NCT06133634 | University of Colorado, Boulder | Phase 1 / Phase 2 |
| Completed | The Effect of NADPH Oxidase and Creatine Supplementation on Microvascular Blood Flow Regulation NCT06018480 | Florida State University | N/A |
| Completed | CPB Prime Fluid Strategies to Preserve Mcirocirculatory Perfusion NCT05647057 | Amsterdam UMC, location VUmc | N/A |
| Completed | Endothelial Protection in Post COVID-19 Patients With Sulodexide NCT05371925 | Centro Medico del Noroeste | Phase 3 |
| Completed | COMP-4 Supplementation and Brachial Artery FMD NCT05595915 | University of California, Los Angeles | Phase 1 / Phase 2 |
| Recruiting | SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery NCT05812755 | Vanderbilt University Medical Center | Phase 4 |
| Completed | Inulin and Nitrate's Effects on Vascular Health and Gut Microbiome NCT06502535 | University of Exeter | N/A |
| Recruiting | Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals NCT05808686 | Medical College of Wisconsin | Phase 2 |
| Completed | The Association Between Food Timing and Composition on Gastrointestinal Injury, Stress Hormone and Gastrointes NCT06403241 | Poznan University of Physical Education | — |
| Completed | Effect of Plasma Ceramides on Peripheral Vascular Function NCT05107869 | Medical College of Wisconsin | N/A |
| Completed | A Trial to Evaluate the Effect of C21 on Endothelial Dysfunction in Subjects With Type 2 Diabetes NCT05831644 | Vicore Pharma AB | Phase 1 |
| Recruiting | The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers NCT05808387 | InCor Heart Institute | N/A |
| Recruiting | Sodium Lowering Vascular Effects Trial NCT05388032 | Tulane University | N/A |
| Completed | Effect of a Specific Aquaporin-1 Inhibitor on Vascular Oxidative Stress in Healthy Volunteers NCT06059131 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Unknown | Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia NCT03255408 | University of Calgary | Phase 1 / Phase 2 |
| Completed | Vascular Injury in Mechanical Ventilation: a Proof-of-Concept Study NCT05538858 | University of Manitoba | — |
| Recruiting | Clinical and Diagnostic Significance of Endothelial Dysfunction and Myocardial Contractility in Patients With NCT05703126 | Samara State Medical University | N/A |
| Unknown | Breaking up Sedentary Time in Rheumatoid Arthritis NCT05284110 | Liverpool John Moores University | N/A |
| Recruiting | Study to Assess Safety and Tolerability of Multiple Doses of EO2002 NCT05636579 | Asociación para Evitar la Ceguera en México | Phase 1 |
| Unknown | All Eyes on PCS - Analysis of the Retinal Microvasculature in Patients With Post-COVID-19 Syndrome NCT05635552 | Technical University of Munich | — |
| Recruiting | Micro-doses of Physical Activity for COPD NCT05553223 | University of British Columbia | N/A |
| Completed | Restoring Glycocalyx Thickness in Older Adults to Improve Vascular Function NCT06071728 | University of Iowa | N/A |
| Unknown | Assessment of the Effect of Non-surgical Periodontal Treatment on Endothelial Function- a Prospective Study NCT05691426 | University of Sharjah | — |
| Completed | Role of Mitochondrial-derived Oxidative Stress to Promote Vascular Endothelial Dysfunction in Non-exercisers W NCT05872139 | Ball State University | N/A |
| Active Not Recruiting | The DISCOVER INOCA Prospective Multi-center Registry NCT05288361 | Yale University | — |
| Recruiting | The Endothelial Cell Dysfunction and Outcome Project for Hematological Neoplasms NCT05502887 | Prof. Dr. Thomas Luft | — |
| Completed | The Dose-response Effects of High Intensity Functional Training on Metabolic Syndrome Risk Factors NCT05001126 | Gary Van Guilder | N/A |
| Recruiting | B-Complex: A Nutraceutical SANS Countermeasure NCT05366933 | National Aeronautics and Space Administration (NASA) | Phase 1 |
| Recruiting | Optimizing Pulsatility During Cardiopulmonary Bypass NCT05344573 | University of Colorado, Denver | — |
| Recruiting | MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sen NCT05065372 | Kalie Tommerdahl | Phase 1 |
| Completed | Night Shift Work, On-shift Napping, and Endothelial Function: A Pilot Study NCT05436951 | University of Pittsburgh | N/A |
| Completed | Inter-individual Physiological Response to a Training and Detraining Period in Cardiometabolic Risk Factors Su NCT05710653 | Cristian Alvarez | N/A |
| Completed | NightWare and Cardiovascular Health in Adults With PTSD NCT05365607 | University of Colorado, Denver | N/A |
| Completed | Acute Responses to Arm-Crank Exercise on Cardiovascular Function of Patients With Peripheral Artery Disease NCT05611021 | University of Nove de Julho | N/A |
| Unknown | Perioperative Plasma Levels of Glycocalyx Markers in Colon Surgery. NCT05419882 | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana | — |
| Unknown | Evaluation of Black Chokeberry Bio Juice on Blood Pressure Levels and Endothelial Damage NCT05912322 | University of Medicine and Pharmacy "Victor Babes" Timisoara | N/A |
| Unknown | The Effect of Dietary Intervation on Endothelial Glycocalyx in COVID-19 Patients. NCT05185934 | University of Athens | N/A |
| Completed | Effect of 2000-meter Rowing Test on Parameters of Intestinal Integrity in Elite Rowers During Competitive Phas NCT06372262 | Poznan University of Physical Education | — |
| Terminated | Assessment of Dapagliflozin on Vascular Health in Patients With Type 2 Diabetes NCT05139914 | Boston University | Phase 4 |
| Completed | Effect of Beetroot Juice on Reducing Hypertension in Autosomal Dominant Polycystic Kidney Disease NCT05401409 | Western Sydney Local Health District | N/A |
| Recruiting | Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmen NCT05000515 | University of Colorado, Boulder | N/A |
| Terminated | Endothelial Protection in Convalescent COVID-19 Patients NCT05252923 | Pirogov Russian National Research Medical University | Phase 4 |
| Unknown | Effects of Ramadan Fasting on Endothelial Function NCT05331443 | University of Monastir | — |
| Completed | Effect of Oral Intake of Bacopa Monneiri on Vascular Oxidative Stress NCT06355167 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Completed | Effect of COVID-19 on Endothelial Function NCT05500560 | University Hospital of Patras | — |
| Withdrawn | Isolation of Cells From Biopsy Tissue to Aid in Kidney Repair NCT04896567 | Brigham and Women's Hospital | Phase 1 |
| Completed | Subclinical Impairment of Cardiovascular System in Patients With Psoriasis NCT05957120 | University Medical Centre Ljubljana | — |
| Unknown | Effects of Nitrate-rich Beetroot Juice in Pregnant Women With High Blood Pressure NCT05241327 | Karolinska Institutet | N/A |
| Completed | Endothelial Function in Mechanical Circulatory Support NCT04539093 | Medical College of Wisconsin | — |
| Completed | Evaluation of Systemic Microvascular Reactivity in Patients With Resistant Hypertension NCT05464849 | National Institute of Cardiology, Laranjeiras, Brazil | — |
| Active Not Recruiting | Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Am NCT04769206 | Vanderbilt University Medical Center | Phase 1 / Phase 2 |
| Completed | Novel Therapeutics and Endothelial Dysfunction in T1DM Patients NCT05857085 | General and Teaching Hospital Celje | Phase 4 |
| Completed | Intermittent Hypoxic-hyperoxic Training in Patients With Cardiovascular Pathology After COVID-19 Infection. NCT05379608 | I.M. Sechenov First Moscow State Medical University | N/A |
| Unknown | Effect of Polyphenol Extract on Cardiovascular Health Markers: a 4 Way Randomised Crossover Study NCT05220059 | University of Ulster | N/A |
| Completed | Comparison of the Effects of Sevoflurane and Desflurane on Endothelial Glycocalyx NCT05068336 | Kocaeli Derince Education and Research Hospital | — |
| Completed | Artery Function Responses to Heat Therapy and Exercise Training NCT04588103 | McMaster University | N/A |
| Terminated | Feasibility of Digital Thermal Monitoring to Assess Endothelium-Dependent Vasodilation in Patients Undergoing NCT05029752 | M.D. Anderson Cancer Center | N/A |
| Completed | Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema NCT04894110 | Emmecell | Phase 1 |
| Active Not Recruiting | Investigation of the Effects of Dietary Nitrate and Sex on COVID-19 Vaccine Induced Vascular Dysfunction in He NCT04889274 | Queen Mary University of London | Phase 1 |
| Unknown | Novel Time-efficient Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure NCT04848675 | University of Colorado, Boulder | N/A |
| Completed | Coronary Artery Endothelial Dysfunction With Drug Coated Balloons NCT04901767 | Norfolk and Norwich University Hospitals NHS Foundation Trust | — |
| Unknown | Microfluidic-based Tactile Sensor in Cardiac Rehabilitation NCT04812600 | Zhili hao | — |
| Terminated | Intravenous Imatinib in Mechanically Ventilated COVID-19 Patients NCT04794088 | Dr. Jurjan Aman | Phase 2 |
| Completed | The Effect of Blood Flow Restriction Applied During Nordic Hamstring Exercise NCT05662891 | Gazi University | N/A |
| Unknown | Managing Endothelial Dysfunction in Critically Ill COVID-19 Patients at LAUMCRH NCT04813471 | Lebanese American University Medical Center | Phase 3 |
| Completed | Circulating Exosomes and Endothelial Dysfunction in Patients With Obstructive Sleep Apneas Hypopneas Syndrome NCT04459182 | University Hospital, Angers | N/A |
| Unknown | Long Term Cardio-Vascular Risk Assessment in CKD and Kidney Transplanted Patients Following SARS-COV-2 NCT05125913 | Grigore T. Popa University of Medicine and Pharmacy | — |
| Completed | The Glycocalyx in COVID-19 Patients. A Pilot Study NCT05137249 | Medical University of Vienna | — |
| Completed | Ultrasound Markers of Systemic Inflammation NCT05798182 | Osijek University Hospital | — |
| Terminated | In Vivo Glycocalyx as Predictor of Complications After Cardiac Surgery NCT04643535 | University Hospital, Rouen | — |
| Completed | Endothelial Damage and Angiogenesis Biomarkers During COVID-19 NCT04609332 | University of Chile | — |
| Unknown | Effect of Berberine Hydrochloride on Blood Pressure and Vascular Endothelial Function in Patients With Hyperte NCT04790942 | Jun Tao | Phase 4 |
| Completed | Creatine Monohydrate Supplementation and Vascular Endothelial Health NCT05014659 | Florida State University | N/A |
| Completed | RGD PET/CT Imaging in COVID-19 Patients NCT04596943 | Radboud University Medical Center | — |
| Recruiting | Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects Wit NCT05906810 | University of Catania | N/A |
| Unknown | COVID-19 : Transcutaneous pO2 and pCO2 as Predictive Factors for Acute Respiratory Destress Syndrome in Patien NCT04524156 | Erasme University Hospital | N/A |
| Recruiting | Biomarkers of Inflammation and Endothelial Dysfunction in Patients With Myocardial Infarction With Non-obstruc NCT06446895 | Hospital Universitario Getafe | — |
| Recruiting | Covid-19 Effects on Arterial Stiffness and Vascular Aging (CARTESIAN) NCT04558450 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | The Effect of Remote Ischemic Conditioning in Patients With Hypercholesterolemia NCT05164185 | Karolinska Institutet | N/A |
| Unknown | Nutritional Intervention With Black Garlic NCT05082350 | Maria Pilar Zafrilla Rentero | N/A |
| Completed | A Phase 1/ Phase 2 Study of TTHX1114(NM141) NCT04520321 | Trefoil Therapeutics, Inc. | Phase 1 / Phase 2 |
| Recruiting | Puberty Suppression and Cardiometabolic Health NCT04482374 | University of Colorado, Denver | — |
| Recruiting | Characterizing the Retinal Microvasculature in Patients with Fabry Disease: a Prospective Observational Study NCT06758648 | Technical University of Munich | — |
| Completed | Microvascular Flow and Reactivity in Patients Presenting in the Acute Phase of COVID-19. NCT04406545 | National Institute of Cardiology, Laranjeiras, Brazil | — |
| Unknown | Assessment of Endothelial and Haemostatic Changes During Severe SARS-CoV-2 Infection NCT04357847 | University Hospital, Rouen | — |
| Unknown | Immune Cells Phenotypes During COVID-19 NCT04816760 | Institut Hospitalo-Universitaire Méditerranée Infection | — |
| Terminated | Interrupting Sitting With High Intensity Exercise on Vascular Function in Adolescents Before and After a Mixed NCT04337385 | University of Exeter | N/A |
| Unknown | Effects of Combined Aerobic and Resistance Training in Patients With Intermittent Claudication NCT04302571 | University Of Perugia | N/A |
| Completed | Apelin as a Potential Treatment for Chronic Kidney Disease NCT03956576 | University of Edinburgh | N/A |
| Completed | Electronic Hookah and Endothelial Cell Function NCT04133376 | University of California, Los Angeles | N/A |
| Completed | "Neighborhood Disadvantage, Sleep and Vascular Health" NCT04576338 | Auburn University | — |
| Active Not Recruiting | Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women NCT04530916 | Colorado State University | Phase 1 / Phase 2 |
| Completed | Apoptosis Proteins and Endothelial Dysfunction in Patients With Atherosclerosis of Peripheral Arteries NCT04502849 | Ryazan State Medical University | — |
| Completed | Impact of Consuming Plant Sterols on Endothelial Function and Blood Pressure NCT03723330 | National University of Singapore | N/A |
| Completed | Influence of Cardiorespiratory Fitness and Body Composition on Resting and Post-exercise Indices of Vascular H NCT06163456 | Towson University | N/A |
| Completed | Management of Endothelial Dysfunction in Patients With Chronic Venous Insufficiency After Endovenous Surgical NCT04180137 | State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia | N/A |
| Completed | Key Dimensions of PTSD and ED NCT03778307 | University of California, Los Angeles | — |
| Recruiting | Microvascular Dysfunction in Obesity NCT04087655 | Florida State University | N/A |
| Completed | Does Nicotine Influence the Risk of Preeclampsia? NCT06645340 | Medical University of Graz | N/A |
| Completed | Assessment of the Relations Between Endothelial and Venous Dysfunctions and Left Ventricular Obstruction in Ge NCT04129905 | University Hospital, Bordeaux | N/A |
| Completed | The Effects of Watermelon Juice Supplementation on Postprandial Vascular Endothelial Function NCT04092439 | Pennington Biomedical Research Center | N/A |
| Completed | Remote Ischemic Preconditioning in Patients Undergoing Acute Minor Abdominal Surgery NCT04156711 | Zealand University Hospital | N/A |
| Completed | Influence of Walnut Intake on Vascular Function and Metabolism NCT03900403 | University of California, Davis | N/A |
| Completed | Effects of Passive Heat Therapy on Oxygen Consumption and Cardiovascular Fitness in Adults NCT04026126 | University of Kansas Medical Center | N/A |
| Completed | Origin of CEC in Patients After Allo-HSCT NCT04038827 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | — |
| Withdrawn | Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical NCT04022161 | Massachusetts General Hospital | Phase 2 |
| Recruiting | Bright Light Exposure in Surgical Patients NCT03822949 | University of Colorado, Denver | N/A |
| Unknown | Effects of Anti-VEGF Targeted Drugs on Patients' Blood Pressure and Endothelial Function NCT04962438 | Peking University Third Hospital | — |
| Completed | Endothelial Injury Mechanism in Elderly Patients Undergoing Major Surgery NCT03639896 | The First Affiliated Hospital of Anhui Medical University | Phase 4 |
| Unknown | Anti-Inflammatory Drug and Endothelial Function NCT04161339 | Instituto de Cardiologia do Rio Grande do Sul | Phase 4 |
| Completed | COronary Microcirculation and Troponin Elevation in Septic Shock NCT06294730 | Karolinska Institutet | — |
| Completed | The Effect Of Preoperative Parameters On Success After DMEK Surgery NCT04420429 | Beyoglu Eye Research and Education Hospital | — |
| Unknown | Glycocalyx Biomarkers in ARDS for Clinical Prognosis and Pulmonary Fibrosis NCT03854565 | Southeast University, China | — |
| Unknown | Analysis of Sublingual Glycocalyx Damage at ICU Admission to Predict Risk of Death NCT03847493 | University Hospital Muenster | — |
| Completed | Be-HealthY: Behavioral Risk Factors for Poor Vascular Health in Youth NCT03934398 | Johns Hopkins University | — |
| Completed | Adrecizumab in Cardiogenic Shock NCT03989531 | Dr. med. Mahir Karakas | Phase 2 / Phase 3 |
| Completed | Short Term Effects of Probiotics in the Human Micro-vascular Physiology NCT05234645 | Sheffield Hallam University | N/A |
| Completed | Low Grade Inflammation in Childhood Obesity : an Independent Risk Factor for Endothelial Dysfunction NCT04181398 | Universitair Ziekenhuis Brussel | N/A |
| Completed | Effects of Aronia Berries on Vascular Endothelial Function and the Gut Microbiota in Middle-Aged/Older Adults NCT03824041 | Colorado State University | N/A |
| Completed | Effect of Local Heat Stress Via Leg Bath on Artery Function NCT03618524 | McMaster University | N/A |
| Completed | Influence of Prior Walking on Postprandial Metabolism in Centrally Obese Men NCT03952000 | Loughborough University | N/A |
| Completed | Resveratrol and Vascular Function in CKD NCT03597568 | Diana Jalal | N/A |
| Unknown | Vascular Functions in Myeloma Patients During Anti-tumor Therapy NCT03776331 | University Hospital, Essen | — |
| Completed | The Cardiovascular Effects of Electronic Hookah Vaping NCT03690427 | University of California, Los Angeles | N/A |
| Withdrawn | Effects of Nitric Oxide on the Endothelium During Hemolysis. NCT03748082 | Massachusetts General Hospital | Phase 2 |
| Completed | Functional Assessment of the Infart-related Artery With Bioactive and Polymer-free Coronary Stents (The FUNCOM NCT04202172 | Institut d'Investigació Biomèdica de Bellvitge | Phase 4 |
| Completed | Correlation Between Circulating Biomarkers of Organs Damage and Intraoperative Hypotension Management NCT03527758 | University of Catania | N/A |
| Completed | Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study NCT03617302 | Gary L. Pierce, PhD | EARLY_Phase 1 |
| Suspended | Anemia Correction and Fibroblast Growth Factor 23 Levels in Chronic Kidney Disease , and Renal Transplant Pati NCT03193073 | Omnia Mohammed Hashem | N/A |
| Completed | Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome NCT03624569 | Ohio State University | N/A |
| Completed | The Acute Effects of Commercially Available Drinks on the Endothelial Function of Humans Following a High-fat NCT03806829 | University of the Highlands and Islands | N/A |
| Completed | Acute Effects of E-Cigarette Aerosol Inhalation NCT03479203 | University of Pennsylvania | EARLY_Phase 1 |
| Completed | Effect of CEAG on Inflammation and Endothelial Function NCT03906825 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | N/A |
| Completed | Subarachnoid Hemorrhage and Soluble Epoxide Hydrolase Inhibition Trial NCT03318783 | Oregon Health and Science University | Phase 1 / Phase 2 |
| Terminated | Infusion of Umbilical Cord Versus Bone Marrow Derived Mesenchymal Stem Cells to Evaluate Cytokine Suppression. NCT03059355 | Joshua M Hare | Phase 1 / Phase 2 |
| Terminated | Effects of TUDCA on Endothelial Function in Type 2 DM NCT03462940 | Boston University | N/A |
| Completed | Effect of Chlorogenic Acids on the Human Vasculature NCT03520452 | Société des Produits Nestlé (SPN) | N/A |
| Completed | Effect of Phenolic Acids on the Human Vasculature NCT03599128 | Société des Produits Nestlé (SPN) | N/A |
| Completed | Potatoes, Hypertension RIsk and Endothelial Function Study NCT03116919 | Brigham and Women's Hospital | N/A |
| Completed | Effects of Ovarian Hormone Suppression on Vascular and Cognitive Function NCT03112226 | University of Colorado, Denver | N/A |
| Completed | Nitrate and Vitamin C on Vascular Health Oxidative Stress NCT04283630 | David Travis Thomas | N/A |
| Completed | Stair Climbing Outcomes in Cardiac Rehabilitation Exercise NCT03235674 | McMaster University | N/A |
| Unknown | RCTrial to Test Low Intensity Shockwave Treatment in Patients With Mild/Moderate Erectile Dysfunction NCT03741439 | IVI Santiago de Chile | N/A |
| Active Not Recruiting | Impaired Endothelial Integrity in Patients With Embolic Stroke of Undetermined Source (ESUS) NCT03609437 | University of Athens | — |
| Completed | Evaluation of Lipid Emulsion on GCX in Critically Ill Patients NCT03216850 | University Hospital Hradec Kralove | — |
| Completed | Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function in PAD NCT03445754 | University of Oklahoma | N/A |
| Completed | Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function and Arterial Stiffness in HFrEF NCT03380156 | University of Oklahoma | N/A |
| Completed | Blueberries for Improving Vascular Endothelial Function in Postmenopausal Women With Elevated Blood Pressure NCT03370991 | Colorado State University | N/A |
| Completed | Effect of Inorganic Nitrate Supplement on Blood Pressure NCT03909789 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | N/A |
| Completed | Flavonols and Endothelial Injury NCT03488823 | Klinik für Kardiologie, Pneumologie und Angiologie | N/A |
| Terminated | Metabolomic Alterations in the Vascular Compartment in Patients With Sepsis NCT03655899 | Pär Johansson | — |
| Completed | Role of Traditional Cigarettes, Electronic and IQOS Cigarettes on Oxidative Stress. NCT03301129 | University of Roma La Sapienza | N/A |
| Completed | Methotrexate, Blood Pressure and Arterial Function in Rheumatoid Arthritis NCT03254589 | Flinders University | Phase 4 |
| Completed | Influence of Prior Walking on Postprandial Metabolism and Endothelial Function. NCT03712501 | Loughborough University | N/A |
| Terminated | Resistance Training and Cardiometabolic Health NCT03325933 | Arizona State University | N/A |
| Unknown | Acute Effects of Intravenous Iron on Oxidative Stress and Endothelial Dysfunction in Non-dialysis CKD NCT03388385 | Carol Davila University of Medicine and Pharmacy | Phase 4 |
| Recruiting | Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research NCT03253705 | National Institutes of Health Clinical Center (CC) | — |
| Terminated | Hookah Smoking, Carbon Monoxide, and Coronary Endothelial Function NCT03166787 | Cedars-Sinai Medical Center | Phase 1 |
| Withdrawn | Predictors of Coronary Artery Calcium Progression in Adults With a Prior Zero Coronary Artery Calcium Score NCT02636062 | San Antonio Military Medical Center | — |
| Completed | Effects of Carbon Monoxide Breathing on Blood Vessel Function NCT03067701 | Cedars-Sinai Medical Center | Phase 1 |
| Unknown | Factor XIII in Major Burns Coagulation NCT03188913 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Unknown | Upper- and Lower-body Resistance Exercise With and Without Blood Flow Restriction on Hemodynamics and Vascular NCT03225898 | Kent State University | N/A |
| Unknown | Bubbles, Stress, Diastole NCT03210012 | Clinica ARS Medica | — |
| Completed | Evolution of Maternal Weight During Pregnancy and Influence on the Endothelial Function in Her Offspring NCT02992106 | Universitair Ziekenhuis Brussel | N/A |
| Completed | The Effect of Childhood Dyslipidemia on Endothelial and Renal Function NCT03856476 | University of Ioannina | — |
| Unknown | The Cerebral-Coronary Connection (C3) Study NCT04131075 | Instituto de Salud Carlos III | — |
| Completed | Effects of Fructose Restriction on Liver Steatosis NCT03067428 | Maastricht University Medical Center | N/A |
| Completed | Evaluation of Endothelial Dysfunction During Aortic Valvular Replacement by Bioprosthesis With and Without Ext NCT03135496 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Endothelial Dysfunction in Perioperative Period NCT03014765 | University Medical Centre Ljubljana | N/A |
| Completed | Artery Function Responses to Changes in Blood Flow NCT02982044 | McMaster University | N/A |
| Completed | Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women NCT03018366 | Cedars-Sinai Medical Center | Phase 2 |
| Completed | Hemostatic Endothelial Dysfunction in Patients With Peripheral Artery Disease NCT04391374 | Ryazan State Medical University | — |
| Completed | CD36 in Nutrient Delivery and Its Dysfunction NCT03012386 | Vanderbilt University Medical Center | Phase 1 / Phase 2 |
| Completed | The Role of Aldosterone in Circulatory Disorders Within Type 2 Diabetes NCT03017703 | University of Southern Denmark | N/A |
| Completed | Effects of Nutraceutical Therapies on Endothelial Function, Platelet Aggregation, and Coronary Flow Reserve NCT02969070 | Federico II University | N/A |
| Completed | The Effect of an Acute Bout of Exercise on High-sugar Meal Induced Endothelial Dysfunction NCT02919488 | Texas Christian University | N/A |
| Unknown | Evaluation of the Association Between Pre-existing Endothelial Dysfunction and the Onset of Vasoplegia During NCT02965339 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Endothelial Microparticles as Potential Biomarkers of Endothelial Dysfunction NCT04512404 | Universiti Sains Malaysia | — |
| Completed | Passive Mobilization and Vascular Function NCT03087643 | Universita di Verona | N/A |
| Completed | Effect of Apple Polyphenols on Vascular Oxidative Stress and Endothelium Function Study (APP trial_2016) NCT03053986 | University of Bologna | N/A |
| Completed | Effect of Febuxostat on Endothelial Dysfunction in Hemodialysis Patients. NCT02866214 | Ain Shams University | Phase 2 / Phase 3 |
| Unknown | Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method NCT02831153 | Ertan YETKIN | N/A |
| Completed | The Effects of High Intensity Interval Exercise in Obese NCT03376906 | Federal University of Paraíba | N/A |
| Completed | Endothelial Function After Cardiac Surgery NCT02882074 | The Cleveland Clinic | N/A |
| Completed | Exercise and Arterial Modulation in Youth NCT02853747 | University of Basel | — |
| Completed | Effects of Incorporating Sprouted and Non-sprouted Chickpea Flour in Pasta Products Analyzed in Vivo Flow-medi NCT03801486 | Montclair State University | — |
| Completed | Hot Flash as a Marker of Cardiovascular Risk in Recent Postmenopause: Effects of Non-hormonal Treatments NCT03149419 | Rio de Janeiro State University | Phase 4 |
| Completed | Trial of Oral Glutamine on Mitochondrial Function in CKD NCT02838979 | University of Washington | Phase 2 |
| Completed | Effect of Aged Garlic Extract (AGE) on Improving Coronary Atherosclerosis in People With Type 2 Diabetes Melli NCT03931434 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | N/A |
| Completed | Effect of Fluid Challenge on Glycocalyx NCT03891342 | University Hospital Hradec Kralove | N/A |
| Completed | Intracoronary Features in the Prognosis of Endothelial Dysfunction and MACES in Population With Acute Coronary NCT03583047 | Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado | — |
| Unknown | Microalbuminuria as a Cardiovascular Risk Factor (PRECISED Substudy) NCT02409511 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Completed | Endothelial Dysfunction and Selenium Status in Children With Acute Systemic Inflammatory Response NCT02619344 | Federal University of São Paulo | — |
| Completed | Effect of Non-alcoholic Beer in Cirrhosis NCT04041115 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | N/A |
| Completed | The Effect of Dietary Nitrates on Physical Performance and Vascular Function in Chronic Kidney Disease NCT04103736 | University of Delaware | N/A |
| Terminated | Effectiveness of Vitamin D Supplementation NCT02513823 | Texas Woman's University | N/A |
| Unknown | Oxidative Stress and Endothelial Function in Pregnancy Complications NCT02603913 | Universiteit Antwerpen | — |
| Completed | Anticancer Treatment of Breast Cancer Related to Cardiotoxicity and Dysfunctional Endothelium NCT02652975 | University of Aarhus | N/A |
| Completed | Peripheral Endothelial Function Assessment of Patients on Ticagrelor vs. Clopidogrel Who Have Undergone PCI NCT02469740 | University Hospital of Limerick | Phase 4 |
| Unknown | Contribution of Renal Function to Endothelial Dysfunction in Living Kidney Donors and Transplant Recipients NCT02515643 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Unknown | Efficacy and Safety Study of Policosanol NCT02543099 | General Hospital of Chinese Armed Police Forces | Phase 3 |
| Completed | Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air NCT02468752 | Göteborg University | Phase 2 / Phase 3 |
| Completed | High-Intensity Exercise and Endothelial Function in Type 1 Diabetes(HIIT-T1D) NCT03451201 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | High Inspiratory Oxygen Fraction on Endothelial Function in Healthy Volunteers NCT02342405 | Zealand University Hospital | N/A |
| Completed | Effects of Oral Supplementation With Creatine on Systemic Microvascular Endothelial Function in Vegetarian Ind NCT02961972 | National Institute of Cardiology, Laranjeiras, Brazil | N/A |
| Unknown | Effect of Ticagrelor Versus Clopidogrel on Endothelial Dysfunction and Vascular Inflammation NCT02379676 | Kiyuk Chang | Phase 4 |
| Completed | Vasculopathic Injury and Plasma as Endothelial Rescue - OCTAplas Trial (EudraCT no. 2014-000452-28) NCT02253082 | Rigshospitalet, Denmark | Phase 4 |
| Completed | Effect of L-Arginine and Pycnogenol on Light to Moderate Hypertension and Endothelial Function NCT02392767 | Dr. Loges & Co. GmbH | N/A |
| Completed | Prematurity as Predictor of Children's Cardiovascular-renal Health NCT02147457 | Universitaire Ziekenhuizen KU Leuven | — |
| Withdrawn | Influence of Nitrates on Bone Remodeling and Endothelial Function in Patients With Type 2 Diabetes Mellitus NCT02011620 | Tameside Hospital NHS Foundation Trust | Phase 4 |
| Completed | Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women NCT02122198 | University of Colorado, Denver | N/A |
| Unknown | The Association Between Severity of Hypertensive Disorder During Pregnancy and Endothelial Dysfunction NCT02334839 | Rabin Medical Center | — |
| Completed | The Effects of Resveratrol and Acute Exercise on Endothelial Function in Postmenopausal Women NCT02256540 | University of Colorado, Denver | N/A |
| Completed | Use of EndoPAT for Measurements of Endothelial Dysfunction in HIV Infected Children and Healthy Controls NCT02324179 | University Hospitals Cleveland Medical Center | — |
| Unknown | Magnetic Resonance Imaging of Vascular Function NCT02206919 | Sunnybrook Health Sciences Centre | — |
| Completed | Comparison of Pure Epicatechin and Cocoa on Markers of Vascular Function NCT02221791 | Wageningen University | N/A |
| Completed | Observational Study of Endothelial Dysfunction in Phenylketonuria NCT02176603 | Charite University, Berlin, Germany | — |
| Unknown | n-3 PUFA for Vascular Cognitive Aging NCT01953705 | Oregon Health and Science University | Phase 2 |
| Completed | CEC Count Changes to Support GvHD Diagnosis. NCT02064972 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | — |
| Completed | Cardiovascular Risk Factors After Single Pancreas Transplantation NCT02066350 | Oslo University Hospital | N/A |
| Completed | Exercise and Repetitive Diving NCT02118207 | University of Split | N/A |
| Completed | Effects of Tomato Sauce on Endothelial Dysfunction Induced by a High Fat Meal in Healthy Subjects NCT01968369 | Universita di Verona | N/A |
| Completed | N-acetylcysteine to Reduce Oxidative Stress and Improve Endothelial Function in HIV-infected Older Adults NCT01962961 | Indiana University | Phase 1 / Phase 2 |
| Completed | Study of the Effects of Negative Emotions on Endothelial Function NCT01909895 | Columbia University | N/A |
| Completed | Vildagliptin vs. Glibenclamide in Endothelial Function in Type 2 Diabetes and Hypertension NCT02145611 | Dr. José Fernando Vilela-Martin MD PhD | Phase 4 |
| Completed | The Relation Between Plasma Irisin Level and Endothelial Dysfunction in Type 2 Diabetes NCT01877603 | Wuhan General Hospital of Guangzhou Military Command | — |
| Unknown | Effect of Different Methodologies on Variability of Brachial Artery Flow Mediated Dilation NCT01899937 | Maastricht University Medical Center | — |
| Completed | Impact of Oranges on Cardiovascular Health NCT01935362 | University of Leeds | Phase 1 / Phase 2 |
| Terminated | Bosentan in Myocardium Metabolism and Perfusion Measured by 18F-FDG and 82Rb PET/CT on PAH and CTEPH NCT02970851 | University of Lausanne Hospitals | — |
| Completed | Recreational Physical Activity and Cardiometabolic Profile NCT02982967 | Federal University of São Paulo | N/A |
| Completed | Effect of Proton Pump Inhibitors on Endothelial Function NCT02022280 | Stanford University | Phase 1 |
| Unknown | The Influence of Antiphospholipid Antibodies on the Relationship Between Hyperurecemia, Gout and Metabolic Syn NCT01818505 | National Taiwan University Hospital | — |
| Completed | Endothelial Dysfunction and Chronic Obstructive Pulmonary Disease NCT02092675 | Andrea Vukic Dugac | — |
| Completed | TyG Index Levels in Klinefelter Syndrome NCT05014997 | Gulhane School of Medicine | — |
| Unknown | CPAP and Nebivolol in Hypertensive Obstructive Sleep Apnea (OSA) Patients. NCT01771406 | Universitaire Ziekenhuizen KU Leuven | Phase 4 |
| Unknown | The Effect of a Diabetic- and a Kidney-like Environment on Gene and Protein Expression in Cultured EC and SMC NCT01423279 | Meir Medical Center | — |
| Recruiting | The Role of Glycocalyx Integrity in the Primary Prevention of Major Cardiovascular Events NCT04646252 | University of Athens | — |
| Completed | Effects of Trans-Resveratrol in Endothelial Function in Hypertensive Patients NCT02616822 | Hospital Universitario Pedro Ernesto | Phase 1 |
| Completed | Microvascular Reactivity in Prepubertal Children NCT03171441 | Rio de Janeiro State University | — |
| Completed | Effects of an Indoor Cycling Program on Cardio-Metabolic Factors in Women With Obesity and Normal Body Weight NCT04456192 | Poznan University of Physical Education | N/A |
| Completed | Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents NCT01746264 | Mayo Clinic | Phase 1 |
| Completed | Effects of Dietary Nitrate on Age-related Vascular Function NCT01729234 | Heinrich-Heine University, Duesseldorf | Phase 1 / Phase 2 |
| Completed | Bioefficacy of Phenolic Acids NCT01781559 | Société des Produits Nestlé (SPN) | N/A |
| Unknown | Outcome After Descemet Membrane Endothelial Keratoplasty (DMEK) and Ultra-thin Descemet Stripping Automated En NCT02020044 | Charite University, Berlin, Germany | N/A |
| Completed | Targeting Inflammation to Treat Cardiovascular Aging NCT01775865 | Gary L. Pierce | Phase 2 |
| Completed | Study on the Effects of Epicatechin and Quercetin Supplementation on Vascular Function and Blood Pressure (FLA NCT01691404 | Wageningen University | N/A |
| Completed | Bone Mineral Markers in Hypogonadism NCT02062307 | Gulhane School of Medicine | — |
| Completed | A Clinical Trial for People HIV+ Age > 50 at Risk for Heart Disease NCT01578772 | University of California, Los Angeles | Phase 2 |
| Completed | Functional Change in Endothelium After Cardiac cAtheterization, With and Without Music Therapy NCT01632670 | Emmanouil Brilakis | Phase 4 |
| Unknown | Study on Correlation Between Vascular ET-1 and Adiponectin in Pediatric Obesity NCT01750333 | Monica Montagnani | — |
| Completed | The Role of Nitric Oxide Synthase Isoforms in the Cardiovascular Effects of Air Pollution NCT00845169 | University of Edinburgh | N/A |
| Completed | The Effect of Cilostazol Compared to Aspirin on Endothelial Function in Acute Cerebral Ischemia Patients NCT03116269 | Ajou University School of Medicine | Phase 4 |
| Completed | Vascular Dysfunction and Antiangiogenic Therapy NCT02161978 | University Hospital, Angers | — |
| Unknown | Mechanisms of Atherogenesis During Post-prandial Time in Childhood Obesity NCT01502826 | Universita di Verona | — |
| Unknown | RAltegravir Switch STudy: Effects on Endothelial Recovery NCT01453933 | UMC Utrecht | Phase 4 |
| Unknown | Maraviroc Abacavir STudy - Effect on Endothelial Recovery NCT01389063 | S.F.L. van Lelyveld | Phase 4 |
| Completed | CoQ10 Biomarker Trial NCT01408680 | University of Washington | N/A |
| Completed | Cardiovascular Effects of Aerosols in Residences Study NCT01570062 | Simon Fraser University | Phase 2 |