NCT03847493

Analysis of Sublingual Glycocalyx Damage at ICU Admission to Predict Risk of Death

Analysis of Sublingual Glycocalyx Damage at ICU Admission to Predict Risk of Death - the ASGARD Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University Hospital Muenster · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this observative, prospective study is to evaluate if and to what extent glycocalyx damage/microcirculation data at admission in the ICU as well as during ICU stay can be predictive of mortality and clinical course in patients presenting with the suspicion of sepsis/septic shock. Therefore, the enrollment of ca 100 ICU patients is planned.

Conditions

• Sepsis
• Septic Shock
• Endothelial Dysfunction

Interventions

Type	Name	Description
OTHER	Endothelial Glycocalyx	Non-invasive assessment of endothelial glycocalyx dimensions.

Timeline

• Start date: 2019-04-15
• Primary completion: 2022-12-30
• Completion: 2023-12-31
• First posted: 2019-02-20
• Last updated: 2022-11-07

Locations

1 site across 1 country: Germany