Trials / Completed
CompletedNCT03112226
Effects of Ovarian Hormone Suppression on Vascular and Cognitive Function
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 19 (actual)
- Sponsor
- University of Colorado, Denver · Academic / Other
- Sex
- Female
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
Complaints about memory and thinking are common in women as they go through menopause. The female hormone estrogen is important for both the health of both the brain and the blood vessels. In Alzheimer's disease there is damage to the blood vessels in the brain. This study will look at how the loss of the female hormone estrogen affects brain function and the health of blood vessels.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | GnRHant + E2 | GnRH antagonist with estradiol add-back |
| OTHER | GnRHant + Placebo | GnRH antagonist with placebo add-back |
Timeline
- Start date
- 2018-02-07
- Primary completion
- 2020-06-06
- Completion
- 2020-06-21
- First posted
- 2017-04-13
- Last updated
- 2021-06-07
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT03112226. Inclusion in this directory is not an endorsement.