| Not Yet Recruiting | Fall Prevention in Mild Cognitive Impairment NCT07507812 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular NCT06566183 | NYU Langone Health | Phase 3 |
| Not Yet Recruiting | The Care for America's Aging Study NCT06021704 | Massachusetts General Hospital | N/A |
| Not Yet Recruiting | Virtual Caregiver Coach for You (ViCCY) NCT07220798 | Visiting Nurse Service of New York | N/A |
| Not Yet Recruiting | Robot-Assisted Meditation for Older Adults With Cognitive Concerns NCT07435220 | Johns Hopkins University | N/A |
| Not Yet Recruiting | Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance NCT06351540 | Johns Hopkins University | Phase 1 |
| Not Yet Recruiting | Efficacy of Spectrally Optimized Light on Cognitive Impairment in Major Depressive Disorder and Its Neuroimagi NCT07508215 | Peking University Sixth Hospital | N/A |
| Not Yet Recruiting | ME/CFS Brain Fog: Cognitive Rehabilitation Trial NCT07523113 | University of Alabama at Birmingham | N/A |
| Not Yet Recruiting | Orthopedic Procedures and Postoperative Delirium in Older Adults in the Czech Republic NCT07432009 | Tomas Bata Hospital, Czech Republic | — |
| Not Yet Recruiting | Remote Ischemic Conditioning for Cognitive Impairment in Cerebral Small Vessel Disease NCT07317557 | Jiangsu Province Nanjing Brain Hospital | N/A |
| Recruiting | Tele-Rehabilitation vs Conventional Rehabilitation for Cognitive Improvement in Stroke Survivors. NCT07504276 | Riphah International University | N/A |
| Recruiting | Cognitive Assessment And Post-Operative Complications After Surgery: Linking Anaesthesia And Risk NCT07470216 | University of Edinburgh | — |
| Not Yet Recruiting | Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT NCT04520139 | University of California, Irvine | Phase 1 / Phase 2 |
| Not Yet Recruiting | TMS for Improving Cognitive Function in Bipolar Disorder NCT07414147 | First Affiliated Hospital of Zhejiang University | N/A |
| Not Yet Recruiting | Effectiveness of Exercise Alone and tDCS+Exercise on Cognitive Function Improvement in Patients With Treatment NCT07404319 | Kit Wa Chan | N/A |
| Not Yet Recruiting | Older Kidney Patient Optimisation Pretransplant NCT07419945 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Active Not Recruiting | Cognitive Task-Based Walking Effects on Cognition, Mood, Sleep, and Quality of Life in Older Adults With Brain NCT07396779 | Medipol University | N/A |
| Recruiting | A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of T NCT07084831 | European Group for Research In Schizophrenia | Phase 3 |
| Recruiting | Living Independence Through Functional Training NCT07125378 | University of Florida | Phase 1 / Phase 2 |
| Not Yet Recruiting | Multicenter RCT of Eye-Brain Imaging in Diabetes Neurovascular Coupling NCT06813274 | Hejiang Ye | Phase 2 |
| Recruiting | Validation of the VIRADIA App for Neurological and Cognitive Diagnostics in Virtual Reality NCT07268079 | Gametherapy | — |
| Not Yet Recruiting | Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity NCT07151430 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease NCT07226219 | St. Jude Children's Research Hospital | Phase 1 |
| Not Yet Recruiting | Effects of Whole Body Vibration Therapy on Cognitive Function, Balance, and Quality of Life in Older Adults Wi NCT06927882 | Jouf University | N/A |
| Recruiting | Epigenetic Enhancement of Cognitive Training in Aging Mood Disorder Populations NCT07404085 | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | N/A |
| Recruiting | Registry Study of Cerebral Small Vessel Disease NCT07342075 | Dongzhimen Hospital, Beijing | — |
| Recruiting | A Sitting Tai Chi Programme for Chronic Stroke Survivors With Post-stroke Cognitive Impairment NCT07512739 | Chinese University of Hong Kong | N/A |
| Recruiting | HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms NCT06930560 | Johns Hopkins University | N/A |
| Recruiting | Milk Fat Globule Membrane-Enhanced RUTF for Children With Severe Acute Malnutrition NCT06869850 | Washington University School of Medicine | N/A |
| Recruiting | A Modified Test of Goal-directed Behaviour: a Feasibility Study NCT07484048 | Gloucestershire Hospitals NHS Foundation Trust | N/A |
| Active Not Recruiting | Community Recreation to Enhance Function in Aging NCT07104435 | State University of New York at Buffalo | N/A |
| Recruiting | Butylphthalide for Cognitive Impairment in Elderly Patients With Focal Epilepsy NCT07193277 | First Affiliated Hospital of Wenzhou Medical University | Phase 4 |
| Not Yet Recruiting | A Study on Functional Connectome and rTMS Intervention of Cognitive Flexibility Impairment in Patients With Ma NCT07161492 | Second Xiangya Hospital of Central South University | N/A |
| Completed | Cognitive Stimulation in Older Adults With Alzheimer's Disease NCT07041008 | Rsocialform - Geriatria, Lda | N/A |
| Not Yet Recruiting | The Resistant Starch Intervention for Cognitive Enhancement NCT07152483 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Not Yet Recruiting | Delirium and Cognitive Impairment Development in Hospitalized Older Adults Under Isolation Conditions NCT07114458 | Universitätsklinikum Hamburg-Eppendorf | — |
| Not Yet Recruiting | (Neuro)Cognitive Remediation for Adults With OSIs NCT06813378 | Nova Scotia Health Authority | N/A |
| Not Yet Recruiting | Smartphone Multimodal Health Intervention for Neurological Enhancement (SHINE) NCT07092371 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | Repetitive Transcranial Magnetic Stimulation and Postoperative Neurocognitive Recovery NCT06482749 | Peking University First Hospital | N/A |
| Not Yet Recruiting | Targeting Sarcopenia and Frailty: Multicomponent Exercise With Focal Muscle Vibration NCT07049809 | Universitat Internacional de Catalunya | N/A |
| Not Yet Recruiting | Development of an Ensemble Learning-based, Multi-dimensional Sensory Impairment Score to Predict Cognitive Imp NCT06783010 | Azienda Sanitaria Locale Bari | — |
| Completed | Exercise-Modulated Cognitive Hormones NCT07341568 | King Saud University | — |
| Recruiting | Cognitive Screening Made Easy for PCPs - Administrative Supplement NCT06928298 | University of Texas at Austin | N/A |
| Recruiting | COgnitioN With VERiciGuat Evaluation in Heart Failure NCT06601465 | University of Alberta | Phase 2 |
| Not Yet Recruiting | Minocycline in Neurocognitive Outcomes - Sickle Cell Disease NCT05605366 | University of Cincinnati | Phase 1 |
| Active Not Recruiting | Transcranial Direct Current Stimulation for Cancer-related Cognitive Impairment in Breast Cancer Survivors NCT07083518 | Anhui Medical University | N/A |
| Not Yet Recruiting | Project ICOPE Brazil: Assessment of Intrinsic Capacity in Brazilian Older Adults NCT06968702 | University of Sao Paulo | — |
| Completed | Cognitive and Physical Frailty as Predictors of Decision Satisfaction in Geriatric Gynecologic Oncology NCT07085000 | Izmir City Hospital | — |
| Recruiting | Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline Dur NCT06727773 | UNC Lineberger Comprehensive Cancer Center | Phase 2 |
| Recruiting | Impact of a Multimodal Lifestyle Intervention on Dementia Risk Factors and Attitude Related to Dementia Risk: NCT07146412 | HudsonAlpha Institute for Biotechnology | N/A |
| Not Yet Recruiting | Estimating Premorbid Intellectual Functioning in Children and Measuring Change in Cognitive Functioning as Chi NCT04153838 | University of Aberdeen | — |
| Withdrawn | SNIFF - 3-Week Aptar CPS Device NCT05006599 | Wake Forest University Health Sciences | Phase 2 |
| Not Yet Recruiting | Impact of Sleep Disorders and Digital Support on Older People's Health NCT06944600 | University of Parma | — |
| Completed | Cognitive Sensorimotor Training With Whole Body Vibration for Cognitive Impairment NCT06927492 | Riphah International University | N/A |
| Recruiting | LSVT Big and Dual Task Training in Cognitive Impaired Patients NCT06927362 | Riphah International University | N/A |
| Recruiting | Visual Frailty in Ageing NCT06604104 | University of Edinburgh | — |
| Not Yet Recruiting | Effect of Vagus Nerve Stimulation Via the Outer Ear on Motor and Cognitive Deficits After Ischemic Stroke NCT06822140 | Rheinburg-Klinik | N/A |
| Not Yet Recruiting | Adaptation and Normalization of a Verbal Episodic Memory Test in French Sign Language NCT06902753 | Poitiers University Hospital | N/A |
| Recruiting | Intermittent Theta Burst Stimulation on Cognitive Impairment of Cerebral Small Vessel Disease NCT06579664 | Beijing Tiantan Hospital | N/A |
| Suspended | Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults NCT06077292 | University of California, San Francisco | N/A |
| Recruiting | Remimazolam for Cataract Surgery NCT05980117 | University of California, Los Angeles | Phase 4 |
| Recruiting | The Association Between Cognitive Function and Neuropathy in Individuals With Type 2 Diabetes NCT06857994 | Steno Diabetes Center Copenhagen | — |
| Recruiting | Induced Pluripotent Stem Cells-derived Small Extracellular Vesicles May Promote Neurological Function and Impr NCT07145294 | Hongmei Wang | Phase 1 / Phase 2 |
| Completed | Effects of Personalized Music Listening in Advanced Alzheimer's NCT06765434 | Okan University | N/A |
| Not Yet Recruiting | Cognitive Load Assessment of Helicopter Pilots in Training NCT06832241 | Direction Centrale du Service de Santé des Armées | — |
| Recruiting | Training Cognition With Neurofeedback After Stroke NCT06852209 | University Hospital, Bordeaux | N/A |
| Recruiting | Effects of Aerobic Exercises on Dual-task Performance and Motor Skills in Children With Mild Cognitive Impairm NCT06867692 | Riphah International University | N/A |
| Not Yet Recruiting | Effects of Blood Pressure on Cognition and Cerebral Hemodynamics in PD NCT06252376 | University of California, San Diego | N/A |
| Not Yet Recruiting | Effectiveness of AV-stimulation in Immersive VR to Improve Visual Perception and Driving Performance NCT05703360 | University Health Network, Toronto | N/A |
| Recruiting | AI-Driven Cognitive Digital Therapeutics for Dementia Management NCT06783465 | Taipei Medical University WanFang Hospital | N/A |
| Completed | Effectiveness of a 3-month Individual Reminiscence Therapy Program in Older Adults With Alzheimer's Disease NCT06812442 | Rsocialform - Geriatria, Lda | N/A |
| Not Yet Recruiting | Investigation of Objective Cognitive Effort in Neuropsychological Evaluation of Psychotic Disorders NCT06782672 | University Hospital, Montpellier | — |
| Recruiting | Nutrition-based Interventions to Prevent Cognitive Decline NCT06853405 | Instituto de Saude Publica da Universidade do Porto | N/A |
| Completed | Cognitive Stimulation and Strength Training in Older Adults With Cognitive Impairment NCT06666088 | University of Jaén | N/A |
| Recruiting | Stroke in Working Age and Job Accommodation in Facilitating Transition Back to Work NCT06709898 | Finnish Institute of Occupational Health | N/A |
| Not Yet Recruiting | Digital Intervention Targeting Cancer-related Cognitive Impairments NCT06693102 | Haukeland University Hospital | N/A |
| Not Yet Recruiting | From Brain Currents to Interpersonal Flow: Investigating the Social Processing Stream of Schizophrenia NCT03543553 | Oslo University Hospital | — |
| Recruiting | Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Faciliti NCT06989619 | Brigham and Women's Hospital | N/A |
| Not Yet Recruiting | Personalized Virtual Environments for Managing Responsive Behaviors in Cognitively Impaired Patients: a Feasib NCT06693193 | Fondazione Bruno Kessler | N/A |
| Recruiting | A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors NCT06411561 | University of Washington | N/A |
| Recruiting | RESET-BRAIN: REhabilitation of SleEp and CogniTive Impairment in BReast Cancer Survivors Using an App-based In NCT06553235 | Aarhus University Hospital | N/A |
| Recruiting | Radialis PET Imager for the Assessment of Neuritic Amyloid Plaque Burden NCT06757569 | University Health Network, Toronto | N/A |
| Recruiting | Theta Deep Brain Stimulation for Cognitive Enhancement in Parkinson's Disease NCT06518824 | University of British Columbia | N/A |
| Withdrawn | Neuromodulation Effects in Older Adults NCT06665022 | University of Florida | N/A |
| Enrolling By Invitation | Somatic and Ear Acupuncture for Dysphagia Rehabilitation and Decannulation After Severe Acquired Brain Injurie NCT06888219 | Fondazione Don Carlo Gnocchi Onlus | N/A |
| Recruiting | Perturbation-Based Treadmill Training to Prevent Unrecovered Falls in Geriatric Patients NCT06652828 | University of Oldenburg | N/A |
| Completed | Turkish Version of the Cognitive Functioning Self-Assessment Scale NCT06678412 | Kutahya Health Sciences University | — |
| Recruiting | Fufang Congrong Yizhi Capsules (FCYC) of Cognitive Impairment After Intracerebral Hemorrhage NCT06673602 | Qinhuangdao Hospital of Traditional Chinese Medicine | Phase 4 |
| Recruiting | Train Your Brain SC: Exercise for People With Mild-moderate Cognitive Impairments NCT06799429 | University of South Carolina | N/A |
| Not Yet Recruiting | Cognitive Impairment in Treated Breast Cancer Survivors: Possible Approaches NCT06662474 | Grigore T. Popa University of Medicine and Pharmacy | N/A |
| Recruiting | Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness NCT07042087 | St. Anne's University Hospital Brno, Czech Republic | N/A |
| Unknown | Group Interval Fitness Program for Adolescents With Cognitive Impairments in the School Setting. NCT06061900 | University of Colorado, Denver | N/A |
| Active Not Recruiting | Motor-cognitive Training Effects on Cognition in Breast Cancer Survivors: the BRAINonFIT Study (BRAINonFIT). NCT06073717 | University of Seville | N/A |
| Active Not Recruiting | Predicting Cognition After DBS for Parkinson's Disease 2 NCT06272968 | Charite University, Berlin, Germany | — |
| Not Yet Recruiting | Functional Magnetic Resonance Imaging Study in Schizophrenia Patients and Correlation With Cognitive Impairmen NCT06471179 | Assiut University | — |
| Recruiting | Cancer and Mild Cognitive Impairment Dyadic Intervention NCT05144516 | Duke University | N/A |
| Recruiting | Motion-based Interactive Technology for Improved Quality of Life in Individuals With Cognitive Impairment NCT06466460 | Marie Matérne | N/A |
| Not Yet Recruiting | Effectiveness of a Strength Program Over Cognitive Functionality in Older Adults NCT06434857 | University of Salamanca | N/A |
| Recruiting | Diagnostic Evaluation of Dementia with Lewy Bodies Using a Multimodal Approach NCT06068361 | Assistance Publique - Hôpitaux de Paris | — |
| Not Yet Recruiting | Early Application of Memantine and Pioglitazone to Protect Cognitive Function After Radiotherapy NCT06594172 | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | Phase 2 |
| Recruiting | Neurodegenerative Diseases Progression Markers (MARKERS-NDD) NCT06596746 | Casa di Cura San Raffaele Cassino | — |
| Recruiting | Impact of Anodal tDCS and Virtual Reality on Cognitive Dysfunction in Patients With Multiple Sclerosis NCT07114809 | Ospedale Policlinico San Martino | N/A |
| Not Yet Recruiting | 12-week Tele-exercise Program in Patients With OSA NCT06467682 | University of Cyprus | N/A |
| Recruiting | Lifestyle for the BRAin Health - Nutrition and Exercise Training Intervention NCT06986096 | Slovak Academy of Sciences | N/A |
| Recruiting | Predicting the Risk of Diabetic Neurodegenerative Disorders by Artificial Intelligence Tools Based on Retinal NCT06541834 | Ospedale San Raffaele | — |
| Recruiting | MODAFIMS: A Trial to Evaluate Predictors of Response to MODAFinil in Patients With Multiple Sclerosis NCT06592352 | Clinical Academic Center (2CA-Braga) | Phase 2 |
| Recruiting | Non-pharmacological Care for Depression in Cancer Patients Using VR and TMS NCT06589544 | University Hospital of Ferrara | N/A |
| Terminated | Ultrasonic Neuromodulation for Treatment of Cognitive Impairment NCT06135051 | University of Utah | Phase 1 / Phase 2 |
| Completed | Community Health Worker-Led Transition Support for Persons Living With Dementia and Caregivers NCT06831318 | University of Texas at Austin | N/A |
| Recruiting | intErnet-based iNterventions FOR Cardiac arrEst suRvivors NCT06395558 | Azienda Usl di Bologna | N/A |
| Recruiting | Early Age-Related Hearing Loss Investigation (EARHLI) NCT06174038 | Columbia University | N/A |
| Not Yet Recruiting | Evaluation of Cognitive and Physical Training on MCI Elders NCT06572878 | Taipei Medical University | N/A |
| Not Yet Recruiting | Cognitive Improvement After Carotid Stenting in Hyperbaric Oxygen Therapy Trial NCT05980195 | Beijing Tiantan Hospital | N/A |
| Recruiting | Multimodal Assesment of Alzheimer Patients NCT06448403 | Norwegian University of Science and Technology | — |
| Recruiting | Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk Factor NCT06088212 | Baker Heart and Diabetes Institute | N/A |
| Completed | Chronic Pain Self-management for Older Adults With Cognitive Impairment: A Randomized Pilot Trial NCT06182423 | University of Michigan | N/A |
| Completed | A Clinical Study to Assess the Effects of JoyRise Recovery Powder on Mitigating Alcohol Aftereffects. NCT06575972 | Joyrise | N/A |
| Recruiting | Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery NCT06452147 | Second Affiliated Hospital of Wenzhou Medical University | N/A |
| Recruiting | Early Intervention for Information Processing Speed Deficits in Acute SCI: A Pilot Study NCT06452264 | Kessler Foundation | N/A |
| Recruiting | Study of ALTO-101 in Patients With Schizophrenia NCT06502964 | Alto Neuroscience | Phase 2 |
| Completed | Prediction of MMSE Scores for Cognitive Impairment NCT06611475 | Blekinge Institute of Technology | — |
| Recruiting | Cognitive Screening and Multidomain Intervention Targeting Cognitive Decline in Type 2 Diabetes (The Brain Car NCT07250789 | Steno Diabetes Center Copenhagen | N/A |
| Recruiting | Clinical Evaluation of Acupuncture Treatment on Alzheimer's Disease in APOE e4 Carriers and Non-Carriers NCT06417086 | ZhanYJ | N/A |
| Recruiting | MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction NCT06191965 | Mclean Hospital | Phase 2 / Phase 3 |
| Recruiting | Cognitive Impairment and Cerebral Haemodynamics in Individuals With Symptomatic Peripheral Arterial Disease NCT06369402 | University of Leicester | — |
| Recruiting | DEliriuM in STroke: the Link Between Stroke, Delirium and Long-term Cognitive Impairment NCT06650436 | Universitair Ziekenhuis Brussel | — |
| Completed | Dietary Supplementation and Cognitive Functions in the Elderly NCT06352099 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Recruiting | Characteristics of Papez Loop Neural Network in T2DM （Type 2 Diabetes Mellitus） NCT06912321 | Nanjing First Hospital, Nanjing Medical University | — |
| Completed | Stanford PIPRA Validation Study in an Elderly Orthopedic Population NCT06567574 | Stanford University | — |
| Completed | Stanford ICU Delirium PIPRA Study NCT06519890 | Stanford University | — |
| Completed | Assess the Effect of Metaxalone 640 mg (M640) Compared to Tizanidine 8 mg on Truck Driving Ability and Cogniti NCT06382662 | Primus Pharmaceuticals | Phase 4 |
| Recruiting | Long COVID Brain Fog: Cognitive Rehabilitation Trial NCT06095297 | University of Alabama at Birmingham | N/A |
| Recruiting | A Mechanistic Study to Investigate tDCS and Working Memory in MCI Patients NCT05998031 | University of Florida | N/A |
| Recruiting | Cognitive Rehabilitation in Post-stroke Cognitive Impairment NCT07251517 | University of Florence | N/A |
| Completed | Compensatory and Restorative Rehabilitation Techniques in Stroke NCT06325085 | Riphah International University | N/A |
| Unknown | Effect of Pentoxifylline on Cognitive Impairment After Ischemic Stroke NCT06344390 | The First Hospital of Hebei Medical University | Phase 1 / Phase 2 |
| Recruiting | Dexmedetomidine on Postoperative Cognitive Dysfunction and Serum Tau-217 Protein. NCT06366412 | Minia University Hospital | Phase 4 |
| Not Yet Recruiting | Cognitive Impairment Cohort Study of the Elderly Population in YuGarden NCT06325527 | Ruijin Hospital | — |
| Recruiting | Gerofit and Cognition NCT06107842 | VA Office of Research and Development | N/A |
| Recruiting | A Pilot RCT to Improve Cognitive Processing Speed in Acute SCI NCT06238492 | Kessler Foundation | N/A |
| Recruiting | Elderly Patients With Type 2 Diabetes and Cognitive Exercises NCT06520995 | Istanbul University - Cerrahpasa | N/A |
| Completed | Effects of Cognitive Versus Task Oriented Training on Balance, Gait and Daily Activity in Chronic Stroke Patie NCT06663657 | Riphah International University | N/A |
| Recruiting | Reducing Cognitive Impairment in Glioma with Repetitive Transcranial Magnetic Stimulation and Cognitive Strate NCT06043765 | Linda Douw | N/A |
| Unknown | Association of History of Concussion With Vestibular Impairment and Cognitive Function in Sports Athletes NCT06340100 | Riphah International University | — |
| Completed | Anticipating Decline and Providing Therapy NCT06182995 | Wake Forest University Health Sciences | N/A |
| Active Not Recruiting | Music Improvisation Training on Cognitive Function in Older Adults NCT06721390 | University of California, San Francisco | N/A |
| Recruiting | Older Adults With Cognitive Impairment Doing Sit to Stands, Walking in Transitional Care Programs: A Feasibili NCT06150339 | University Health Network, Toronto | N/A |
| Unknown | Increasing Physical Activity Through Personalised Motivational Messaging to Improve Cognitive Function in Lung NCT06003335 | The University of Hong Kong | N/A |
| Enrolling By Invitation | Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015) NCT06245031 | Cognito Therapeutics, Inc. | N/A |
| Recruiting | Multidimensional Rehabilitation Programs for Cognitive Impairment in Comorbid Outpatients: a Randomized Contro NCT05954741 | Istituti Clinici Scientifici Maugeri SpA | N/A |
| Recruiting | Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventil NCT06312956 | Istituto Auxologico Italiano | — |
| Recruiting | A Study of Healthy Microbiome, Healthy Mind NCT06020703 | Mayo Clinic | N/A |
| Recruiting | Long-term Cognitive and Functional Impact of Proton-therapy or Modern Fractionated Radiotherapy in Cavernous S NCT05895344 | Centre Francois Baclesse | N/A |
| Recruiting | Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury NCT05762796 | State University of New York at Buffalo | N/A |
| Recruiting | Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy NCT06051240 | Region Stockholm | Phase 2 |
| Recruiting | Optimized Rehabilitation of Older Adults With Hip Fracture and Signs of Cognitive Impairment - Feasibility Stu NCT06286722 | Lolland Community, Denmark | N/A |
| Recruiting | Essential Fats For Enhancing Cognitive Thinking (EFFECT) Study NCT06223672 | Ohio State University | N/A |
| Unknown | The Clinical Impact of the Novel Alzheimer's Blood-based Biomarkers NCT06246019 | Hospital del Mar Research Institute (IMIM) | — |
| Active Not Recruiting | Cognitive Screening Made Easy for PCPs - R33 Phase NCT06162026 | University of Texas at Austin | N/A |
| Unknown | Smart Taiko-Drum Playing for Older Adults With Cognitive Frailty NCT06115889 | The Hong Kong Polytechnic University | N/A |
| Not Yet Recruiting | Cognitive and Neural Assessment Platform and Localized Norm for Macau Older Adults. NCT06239922 | University of Macau | — |
| Unknown | PATH Program for for Severely Frail or Cognitively Impaired Patients Scheduled for Cancer Surgery. NCT06022666 | Nova Scotia Health Authority | N/A |
| Recruiting | Primary Care Detection of Cognitive Impairment Leveraging Health & Consumer Technologies in Underserved Commun NCT05607732 | Northwestern University | N/A |
| Unknown | The Effect of Aromatherapy on Sleep and Cognitive Level in the Elderly NCT06208800 | Medipol University | N/A |
| Completed | Predictive Efficacy of Ratio of Median Frequency to Spectral Edge Frequency Used in the Depth of Anaesthesia M NCT06644209 | Ankara University | — |
| Active Not Recruiting | Early Genetic Identification of Obesity NCT06239064 | Rolfs Consulting und Verwaltungs-GmbH (RCV) | — |
| Recruiting | Comparing Fluid Responsiveness Assessment Methods in Patients With Impaired Consciousness NCT06180902 | Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology | N/A |
| Withdrawn | The Therapeutic Effect of Computer-assisted Cognitive Function Training on Cognitive Dysphagia After Stroke NCT06215729 | Zeng Changhao | N/A |
| Completed | Rhythmic Exercise in Older Adults With Cognitive Impairment NCT06130878 | University of Jaén | N/A |
| Unknown | "Cognitive Rehabilitation With Direct Current Transcranial Stimulation in Post-Traumatic Brain Injury Patients NCT06228872 | Mutual de Seguridad Hospital Clinico | N/A |
| Enrolling By Invitation | Cerebrolysin in Critically Ill Patients With Delirium NCT06677502 | Medical University of Lublin | N/A |
| Active Not Recruiting | Polyamine Treatment in Elderly Patients With Coronary Artery Disease NCT06186102 | University of Aarhus | Phase 2 |
| Unknown | The Effects of DPPIs on Cognitive Function of Diabetic Patients NCT06164535 | Beni-Suef University | Phase 4 |
| Completed | HEARS-SLP: Providing SLP-Delivered Hearing Health Care to Individuals With Cognitive Impairment NCT06008782 | Johns Hopkins University | N/A |
| Recruiting | Evaluating the Efficacy of the Pain Identification and Communication Toolkit NCT06168604 | Weill Medical College of Cornell University | N/A |
| Recruiting | Choline to Improve Malnutrition and Enhance Cognition NCT06154174 | Washington University School of Medicine | N/A |
| Enrolling By Invitation | Computerized Training of Attention and Working Memory in Post COVID-19 Patients With Cognitive Complaints NCT05831839 | Erasmus Medical Center | N/A |
| Completed | Quality-of-Life-and-Cognitive-Oriented Rehabilitation Through the NeuronUP in Alzheimer's Disease NCT06499272 | Universidad Rey Juan Carlos | N/A |
| Recruiting | Machine Learning-based Longitudinal Study of Post-ICU Syndrome Development Trajectory in Critically Ill Patien NCT06427265 | The Affiliated Hospital Of Guizhou Medical University | — |
| Unknown | Study of Brain Activations and Physiological Responses Using NeuroBiofeedback in Patients With Multiple Sclero NCT06239090 | IRCCS Centro Neurolesi Bonino Pulejo | N/A |
| Unknown | Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey NCT06025877 | C2N Diagnostics | — |
| Recruiting | Adiposity, Cardiometabolic and Neurocognitive Health Among Ethnic Groups: a Feasibility and Pilot Study NCT06435611 | King's College Hospital NHS Trust | — |
| Active Not Recruiting | Optimal Timing of Computerized Cognitive Training for Older Intensive Care Unit Survivors NCT05467410 | University of Washington | N/A |
| Completed | Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functionin NCT06156202 | University of Pennsylvania | N/A |
| Active Not Recruiting | Remote Game-based Exercise Program for Cognitive and Motor Function Improvement NCT05235113 | University of California, Los Angeles | N/A |
| Completed | Dance Intervention on Cognitive Functions and Quality of Life in Chronic Stroke NCT06145503 | Karadeniz Technical University | N/A |
| Unknown | Modifying Working Memory With Brain Stimulation NCT06119620 | Maastricht University | N/A |
| Recruiting | Effect and Mechanism of Brain Stimulation for Parkinson's Disease With Cognitive Impairment NCT06090682 | Tianjin Huanhu Hospital | — |
| Enrolling By Invitation | Prediction of Delayed Cognitive Impairment in Cardiac Arrest Survivors With Good Neurological Outcomes NCT05830422 | Chungnam National University Hospital | — |
| Active Not Recruiting | PAMNEU - Memory in Neurology NCT06154564 | Charles University, Czech Republic | — |
| Active Not Recruiting | Impact of Resistance Training Volume on Cognitive Function and Physical Performance in Cognitively Impaired In NCT06528951 | University of Beira Interior | N/A |
| Terminated | Occurrence and Influencing Factors of Cognitive Impairment in Elderly Patients With Schizophrenia and NCT06949657 | Third People's Hospital, Huzhou City, Zhejiang Province, China | N/A |
| Completed | The Efficacy and Safty of FMT in Patients With CID NCT05917379 | Peking University Sixth Hospital | Phase 1 / Phase 2 |
| Completed | Urolithin A Supplementation in Middle-aged Adults With Obesity NCT05921266 | University of Oklahoma | N/A |
| Unknown | Safety, Efficacy, and Dosing of VIX001 in Patients With Neurological Symptoms of Post Acute COVID-19 Syndrome NCT05947617 | Neobiosis, LLC | Phase 1 |
| Completed | Delta Waves and Cognitive Recovery NCT05924737 | Institut de Recherche Biomedicale des Armees | N/A |
| Active Not Recruiting | Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer ( NCT06053775 | University of Santiago de Compostela | N/A |
| Recruiting | Technological Balance and Gait Rehabilitation in Patients With Multiple Sclerosis. NCT05983809 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Recruiting | Psychological Treatment to Support the Consequences of Cognitive Impairment NCT04356924 | Karolinska Institutet | N/A |
| Completed | Influence of Overground Walking on Biomarkers, Cognitive Function, and Quality of Life in Elderly With Mild Co NCT06029920 | Universitas Padjadjaran | N/A |
| Recruiting | The Effect of Upper Limb Low-intensity Motor Control Training Program on Cognitive Function in Healthy Older A NCT06962722 | University of Nottingham | N/A |
| Completed | Negotiation Training for Caregiver Communication in AD NCT04837937 | Northwestern University | N/A |
| Completed | Dose-effect Relationship of Tai Chi on Health Promotion in Different Age Groups NCT06307483 | Beijing Sport University | — |
| Completed | A Technology-Driven Intervention to Improve Early Detection and Management of Cognitive Impairment NCT05723523 | HealthPartners Institute | N/A |
| Recruiting | pBFS-guided iTBS Over the Left DLPFC for Chronic PSCI NCT05953415 | Changping Laboratory | N/A |
| Recruiting | 5-Cog 2.0: A Pragmatic Clinical Trial NCT05515224 | Albert Einstein College of Medicine | N/A |
| Recruiting | The Beijing Longitudinal Disability Survey in Community Elderly NCT06863727 | Xuanwu Hospital, Beijing | — |
| Unknown | The StrokeCog Study: Cognitive Rehabilitation Intervention in Stroke NCT06021470 | Royal College of Surgeons, Ireland | N/A |
| Completed | High-frequency tRNS for Sleep Disturbances in Neurocognitive Disorders Due to Vascular Disease NCT06169254 | Chinese University of Hong Kong | N/A |
| Recruiting | Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Old NCT06013579 | University of Alabama at Birmingham | N/A |
| Recruiting | Stepcare Extended Follow-up Substudy NCT06207942 | Region Skane | N/A |
| Completed | Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity NCT06242535 | Hoskinson Health and Wellness Clinic | EARLY_Phase 1 |
| Completed | Intensive Aerobic and Resistance Exercise Program (IAREP) NCT06401733 | National University of Singapore | N/A |
| Enrolling By Invitation | The Effect of OSA on Brain Waste Clearance NCT05606991 | Woolcock Institute of Medical Research | N/A |
| Active Not Recruiting | Exercise Training, Cognition, and Mobility in Older Adults With Multiple Sclerosis NCT05930821 | University of Illinois at Chicago | N/A |
| Recruiting | Effect of Technology on Cognitive Function in Elderly NCT06378606 | Nourhan Hesham Ali | N/A |
| Unknown | Effect of a fNIRS-based Personalized Multi-domain Intervention on Cognitive in Elderly Population With High Ri NCT05930249 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | Incidence and Factors Associated to the Development of PICS-F Among ICU Relatives: A Longitudinal Exploratory NCT05827354 | Pontificia Universidad Catolica de Chile | — |
| Recruiting | A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses NCT05877196 | Arizona State University | N/A |
| Terminated | Mitigation of Postoperative Delirium in High-Risk Patients NCT05777187 | Icahn School of Medicine at Mount Sinai | N/A |
| Completed | Contextualized Neuropsychological Rehabilitation for CNS Cancer Survivors: The ImPACT Program NCT05858359 | Aarhus University Hospital | N/A |
| Unknown | Linus Health CDS Retrospective Validation Study NCT05900310 | Linus Health, Inc. | — |
| Unknown | Effects of a Daily Cognition Training in Older Adults Without Cognitive Impairment NCT05688163 | University of Salamanca | N/A |
| Recruiting | A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China NCT05886114 | Zhejiang University | N/A |
| Recruiting | Cerebral Protection in Transcatheter Left Atrial Appendage Occlusion NCT05369195 | Silesian Centre for Heart Diseases | N/A |
| Completed | Comparison of the Effects of Physical Activity and Virtual Reality Training in Patients With Schizophrenia NCT07173465 | Yeditepe University | N/A |
| Completed | Addressing Problems in Managing Daily Tasks Due to Poststroke Cognitive Impairments NCT05829421 | Emma Ghaziani | N/A |
| Enrolling By Invitation | REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study NCT05611918 | Johns Hopkins University | — |
| Unknown | ExerG: Video Game-based Physical Cognitive Training for Patients: a Usability Study NCT05967078 | Frank Behrendt | N/A |
| Recruiting | Autoimmune Dementia: Predictors of Neuronal Synaptic Antibodies in Patients With New-ONset Cognitive Impairmen NCT06321588 | Azienda Usl di Bologna | — |
| Not Yet Recruiting | LA Improves the Prognosis of Patients With ICVD NCT05845983 | Huaqiu Zhang | N/A |
| Recruiting | Immersive Virtual Reality Techniques on the Effects on Cognition in People With Cancer NCT05907265 | Consorci Sanitari de Terrassa | N/A |
| Unknown | Implementation and Evaluation of Improved Access to Medical Imaging for Geriatric Patients of The Royal Ottawa NCT05428475 | Tim Lau | Phase 3 |
| Completed | Home Alone: An Intervention for People With Cognitive Impairment Who Live Alone NCT05746390 | University of Minnesota | N/A |
| Recruiting | Benefits of Nicotinamide Riboside Upon Cognition and Sleep NCT05500170 | State University of New York at Buffalo | N/A |
| Terminated | Addressing Cognitive Fog in Long-COVID-19 Patients NCT05597722 | Eva Szigethy | Phase 4 |
| Unknown | Cognitive Processing Slowness as a Marker of Cognitive Impairment in Non-central Nervous System Cancer Patient NCT05754060 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Hjernegym - Effects of Exergaming in Psychosis: a Clinical Intervention Study NCT05858255 | Sykehuset i Vestfold HF | N/A |
| Recruiting | Investigating Dynamic Interactions in Distributed Cognitive Control Networks NCT05927974 | University of Alabama at Birmingham | — |
| Withdrawn | Preventing and Managing Cognitive Impairment NCT05471141 | Charles Drew University of Medicine and Science | N/A |
| Active Not Recruiting | PAPSY - Memory in Psychiatry NCT05843357 | Charles University, Czech Republic | — |
| Completed | Effects of Nintendo Switch on Rehabilitation Programs for Elderly People With Cognitive Impairment NCT06129630 | Universidad Rey Juan Carlos | N/A |
| Completed | Neighborhood-based Physical and Social Activity for Older Black Caregivers and People Living With Dementia NCT05658328 | Oregon Health and Science University | N/A |
| Unknown | Impact of TAVI on Cognition, Mood and Health-related Quality of Life NCT04371172 | Medical University of Graz | — |
| Active Not Recruiting | Technology Assisted Cognitive Behavioural Therapy Intervention for Anxiety in People Living With Cognitive Imp NCT05528302 | The University of Queensland | N/A |
| Unknown | Tau And Connectomics In TES Study NCT05490576 | Macquarie University, Australia | Phase 1 |
| Unknown | Gestational Diabetes Mother-infant Cohort NCT06021691 | Gansu Provincial Maternal and Child Health Care Hospital | — |
| Completed | Effects of Altitude-like Cognition Training on Neuroplasticity and Cognitive Functions NCT06121206 | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | N/A |
| Active Not Recruiting | Digitally Supported Lifestyle Programme to Promote Brain Health Among Older Adults NCT05565170 | Finnish Institute for Health and Welfare | N/A |
| Recruiting | METformin and FINGER Intervention to Prevent Cognitive Impairment and Disability in Older Adults at Risk for D NCT05109169 | Imperial College London | Phase 2 |
| Completed | Personalized Virtual Reality Naturalistic Scenarios in Cognitive Impairment NCT05863065 | University of Padova | N/A |
| Recruiting | WHIte MAtter Hyperintensity Shape and Glymphatics NCT06010511 | Leiden University Medical Center | — |
| Active Not Recruiting | Biomarkers Associated With Postoperative Cognitive Dysfunction NCT05464355 | University of Oxford | — |
| Completed | Cognitive Effects of tDCS and tRNS in Schizophrenia NCT06155786 | The National Brain Mapping Laboratory (NBML) | N/A |
| Unknown | Effect of Preventive Cognitive Training on Cognitive Impairment After Stroke in Acute Stage NCT05648149 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Withdrawn | Goal Management Training in Individuals With PTSD NCT04457271 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Unknown | Psychological Evaluation After SCS Implantation NCT05624814 | University Magna Graecia | — |
| Withdrawn | Therapeutic Effect of Transcranial Magnetic Stimulation on Memory Impairment in Patients After Stroke NCT05578183 | China Rehabilitation Research Center | N/A |
| Not Yet Recruiting | Cognitive Impairment Cohort Study of the Elderly Population in SheMountain NCT05667935 | Ruijin Hospital | — |
| Not Yet Recruiting | LA Improves the Prognosis of Patients With ICVD After Surgery NCT05656209 | Huaqiu Zhang | N/A |
| Unknown | Baduanjin Exercising Effects on Sub-clinical Hypothyroidism and Cognitive Problems NCT05803967 | Cairo University | N/A |
| Recruiting | Hainan Community Cognition Cohort NCT06686186 | Hainan Medical College | — |
| Completed | Preoperative Survey NCT05653154 | University Health Network, Toronto | — |
| Active Not Recruiting | A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011) NCT05637801 | Cognito Therapeutics, Inc. | N/A |
| Completed | A Study to Evaluate RL-007 in the Treatment of Cognitive Impairment Associated With Schizophrenia (CIAS) NCT05686239 | Recognify Life Sciences | Phase 2 |
| Enrolling By Invitation | Cognitive Remote Assessment Using FLAME (CRA-FLAME) NCT05624632 | Barcelonabeta Brain Research Center, Pasqual Maragall Foundation | — |
| Recruiting | Mind Your Heart-II NCT05431192 | The Miriam Hospital | N/A |
| Completed | Xanamem® in Adults With Major Depressive Disorder and Impaired Cognition (XanaCIDD) NCT05657691 | Actinogen Medical | Phase 2 |
| Recruiting | Diet and Cognitive Training in Hematologic Cancer Survivors NCT05708716 | University of Alabama at Birmingham | N/A |
| Recruiting | Effect of the Administration of a Symbiotic (E. Faecium and Agave Inulin) on Mild Cognitive Impairment in Olde NCT05688618 | Anahuac University | N/A |
| Completed | Digital Sleep Therapy for Older Adults With Cognitive Impairment NCT05173844 | Woolcock Institute of Medical Research | N/A |
| Recruiting | Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Stu NCT06336174 | Anhui Medical University | — |
| Unknown | Hyperspectral Retinal Observations for the Cross-sectional Detection of Alzheimer's Disease NCT05604183 | Mantis Photonics AB | N/A |
| Unknown | Normal Pressure Hydrocephalus Biomarkers Investigation NCT05562596 | University of Roma La Sapienza | — |
| Unknown | Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients NCT05595109 | Tanta University | Phase 2 / Phase 3 |
| Completed | Sleep Hygiene Education, ReadiWatchTM Actigraphy, and Telehealth Cognitive Behavioral Training for Insomnia Ef NCT05582759 | University of Kansas Medical Center | N/A |
| Unknown | Safety and Dosage of a Computerized Cognitive Training Program for Cognitive Dysfunction After COVID-19 NCT05582603 | Universidad Antonio de Nebrija | Phase 1 / Phase 2 |
| Unknown | Relationship and Central Mechanism Between Diabetes and Cognitive Impairment Based on Simultaneous EEG-fMRI Ap NCT05545657 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | — |
| Unknown | Establish Diagnostic Models Based on Olfactory Function and Odor-induced Brain Activation for Diabetes-Related NCT05543967 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | — |
| Completed | Impact of Music Improvisation Training on Cognitive Function in Older Adults NCT05980286 | University of California, San Francisco | N/A |
| Completed | Long-term Quality of Life and Prognostic Factors in Severe COVID-19 Patients and Their Relatives NCT05520047 | Centre Hospitalier Régional Metz-Thionville | — |
| Unknown | Validation of a Digital Self-Administered Cognitive Screening Tool: MoCA-XpressO NCT05879562 | MoCA Clinic and Institute | N/A |
| Completed | Effect of Immersive Virtual Reality-based Cognitive Remediation in Patients With Mood - or Psychosis Spectrum NCT06038955 | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | N/A |
| Unknown | Effects of Different Doses of Vitamin D on Cancer-related Cognitive Impairment in Patients With Gastrointestin NCT05552729 | Yangzhou University | Phase 1 / Phase 2 |
| Completed | Prevalence and Recognition of Cognitive Impairment in Hospitalized Patients: a Flash Mob Study NCT05395559 | University Medical Center Groningen | — |
| Completed | Atrial Fibrillation Follow-up Investigation to Recover Memory and learnING Trial NCT05374642 | Beijing Anzhen Hospital | N/A |
| Completed | Cognitive Rehabilitation for Post-COVID-19 Cognitive Impairment NCT05498493 | Icahn School of Medicine at Mount Sinai | N/A |
| Terminated | The Effect of Acute Exercise on Cardiac Autonomic, Cerebrovascular, and Cognitive Function in Spinal Cord Inju NCT05542238 | State University of New York at Buffalo | N/A |
| Recruiting | TDCS to Improve Post-Stroke Cognitive Impairment NCT05195398 | Johns Hopkins University | N/A |
| Unknown | Effect of Circadian Light on Hospitalized Persons With Dementia and Older Adults With Cognitive Impairments. NCT05535790 | Zealand University Hospital | N/A |
| Recruiting | The Evolution and Prognosis of Moyamoya Disease NCT05619068 | Chinese PLA General Hospital | — |
| Completed | Effect of BrainPhyt, a Microalgae Based Ingredient on Cognitive Function in Healthy Older Subjects NCT04832412 | Microphyt | N/A |
| Unknown | Hypnosis in Working Memory Rehabilitation NCT05287542 | Sunnaas Rehabilitation Hospital | N/A |
| Recruiting | Cognitive Decline and Underlying Mechanisms in Asymptomatic Intracranial Artery Stenosis Patients NCT05504330 | Anhui Medical University | — |
| Recruiting | A Digital Life Story to Support Person-centred Care for Older Adults With Dementia Perspectives NCT06337201 | Blekinge Institute of Technology | — |
| Completed | SimpleC Wellness Platform With Social Robot Interaction (Long-term) NCT05599503 | SimpleC, LLC | N/A |
| Unknown | Motor-cognitive Dual-task in Healthy Older Adults and Early Parkinson's Disease Patients NCT05477654 | Science and Research Centre Koper | — |
| Active Not Recruiting | Identification of Neuroprognostic Factors for Out-of-hospital Cardiopulmonary Arrest (MIRA29) NCT06569134 | University Hospital, Brest | — |
| Completed | Istradefylline for Parkinson Disease With Cognitive Impairment NCT05333549 | Virginia Commonwealth University | Phase 2 |
| Unknown | Postoperative Delirium in the ICU Setting of an Eastern European Centre NCT05474872 | Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor | — |