NCT06986096

Lifestyle for the BRAin Health - Nutrition and Exercise Training Intervention

Lifestyle for the BRAin Health - Nutrition and Exercise Training Intervention, LIBRA-NET

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Slovak Academy of Sciences · Other Government
• Sex: All
• Age: 60 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Due to the increasing incidence of dementia and the lack of causal treatment, non-pharmacological interventions represent an attractive and effective therapeutic strategy of neurodegenerative diseases, such as Alzheimer's disease. The aim of the study is to assess the impact of a supervised 9-month intervention with aerobic-strength training and nutritional counseling compared to cognitive training and stretching on the brain, cognitive and motor functions, metabolism, physical fitnes and plasma markers of neurodegenertion in older adults at increased risk of developing Alzheimer's disease.

Conditions

• Aging
• Alzheimer Disease
• Life Style, Healthy
• Exercise
• Cognitive Impairment

Interventions

Type	Name	Description
BEHAVIORAL	Aerobic-strength training and nutritional counseling	The intervention consists of a structured program that includes aerobic-strength training (1h training, 3 times per week) conducted by professional trainers combined with nutritional counseling.
BEHAVIORAL	Cognitive training and stretching.	The intervention consists of a structured program that includes cognitive training combined with stretching training (90mins training, 2x per week).

Timeline

• Start date: 2024-09-01
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2025-05-22
• Last updated: 2025-05-29

Locations

1 site across 1 country: Slovakia