Clinical Trials Directory

Trials / Sponsors / Guy's and St Thomas' NHS Foundation Trust

Guy's and St Thomas' NHS Foundation Trust

Academic / Other · 283 registered clinical trials52 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingSymptoms of Anxiety and/or Depression and SDM in Older Patients With CLTI
Critical Limb Threatening Ischaemia, Depression Disorder, Anxiety
2026-06-01
Not Yet RecruitingComparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term.
Pacemaker-Induced Cardiomyopathy, Tricuspid Regurgitation, Right Ventricular Dysfunction
2026-06-01
Not Yet RecruitingMechanisms of Atrial Pathoelectrophysiology in HCM
Hypertrophic Cardiomyopathy (HCM), Atrial Fibrillation (AF)
2026-03-08
Not Yet RecruitingThe LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Study
Bacterial Vaginosis, Candida Vaginal
N/A2026-03-01
Not Yet RecruitingOlder Kidney Patient Optimisation Pretransplant
Kidney Disease, Kidney Failure, Frailty
N/A2026-02-02
Not Yet RecruitingImproving Genetic Medicine for Ethnic Minority Groups
Genetic Testing
2026-01-30
RecruitingExploring if Patients Can Safely and Easily Swab Their Own Surgical Wounds at Home
Cardiac Surgery, Infection, Soft Tissue, Wound Healing
N/A2026-01-06
Not Yet RecruitingLifting the Impacted Fetal Head; the Fetal Pillow and Tydeman Tube Trial
Impacted Fetal Head, Full Dilatation Caesarean Section
N/A2026-01-01
Not Yet RecruitingThe Use of Urinary Dickkopf 3 (u DKK3) as a New Biomarker Which Can Identify Patients at High Risk of Renal Al
Renal Transplant Failure
2026-01-01
Not Yet RecruitingReal-world Exploration of Digital iNnovation in the Management of Excess Weight
Obesity
N/A2025-12-08
Not Yet RecruitingInflammation-resolution Therapy in MINST of Periodontal Intrabony Defect: a Pilot Randomised Controlled Trial
Periodontal Diseases, Periodontitis
N/A2025-11-01
RecruitingOptimising the Delivery of Diabetes Distress Informed Care for Its Prevention, Detection, and Management in Ad
Diabetes Type 1
N/A2025-10-31
Not Yet RecruitingMechanistic Study of Anti-Platelet Therapy in Atherosclerosis
Peripheral Arterial Disease, Silent Atherosclerosis
N/A2025-10-01
Not Yet RecruitingMultIple Long-term Conditions in Pregnancy and Experiences of Midwifery Care
How Pregnant and Postnatal Women With Two or More Long-term Health Conditions Experience Midwifery Care as Part of Multi-disciplinary Maternity Care
2025-10-01
Not Yet RecruitingEvaluation of Seismocardiography(SCG) for Assessing Fitness and Predicting Outcomes in Oesophageal Cancer Surg
Oesophageal Cancer, Oesophageal Adenocarcinoma, Prehabilitation
2025-09-15
Not Yet RecruitingIdentifying Fundamental Mechanisms of Skeletal Muscle Ageing in Older Men Undergoing Androgen Deprivation Ther
Sarcopenia, Prostate Cancer, Muscle Atrophy
2025-09-01
Not Yet RecruitingNutcracker: Can Almond Nut Consumption Improve Nocturnal Glycaemic Control in Women With Gestational Diabetes
Gestational Diabetes
N/A2025-07-01
Not Yet RecruitingImproving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol
Intensive Care Medicine, Respiratory Distress Syndrome (RDS), Sedation and Analgesia
2025-06-30
RecruitingAssessing the Efficacy of Photodynamic Therapy for Preventing Surgical Site Infections
Surgery, Nasal Disease, Light; Therapy, Complications
N/A2025-06-04
RecruitingFasting Induced Hypoglycaemia in Anaesthetised Paediatric Patients
Hypoglycemia; Iatrogenic, Anesthesia, Pediatrics
2025-05-12
Not Yet RecruitingEffects of Vibrating Mesh Nebulisation in Patients With COPD During Non-invasive Ventilation (VMN-NIV)
COPD (Chronic Obstructive Pulmonary Disease), Non-invasive Ventilation
N/A2025-03-21
Not Yet RecruitingEffects of Vibrating Mesh Nebulisation in Patients on Long-term Tracheostomy Ventilation: a Pilot Randomised C
Long-term Tracheostomy Ventilated Patients
N/A2025-03-01
RecruitingAssessing Cancer Treatment Response to Therapy Using 18F-FSPG PET
Cancer, Diagnosis, Resistant Cancer
2025-02-19
RecruitingWISDOM UK: Low Dose-intensity Versus Standard Dose-intensity CRRT in Critically Ill Patients
Acute Kidney Injury (Nontraumatic), Dialysis; Complications
N/A2025-02-15
RecruitingSupported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease
COPD, COPD Exacerbation
Phase 32025-01-30
Not Yet RecruitingUltrasound Prediction of Successful Balloon Assisted AVF Maturation
End Stage Renal Disease (ESRD), Chronic Kidney Disease Requiring Hemodialysis
2025-01-13
RecruitingInvEstigating oeStrogen Signalling and the Effect upoN the exTracelluar Matrix In pAtients With Obstructive Lu
Chronic Obstructive Lung Disease, Respiratory Ilness, Estrogen Deficiency
2024-12-01
Not Yet RecruitingScintigraphy for Prediction In Rheumatoid Intentional Therapy Tapering
Rheumatoid Arthritis
2024-12-01
Not Yet RecruitingThe Inflammatory Profile of Exacerbations in Patients With Severe Asthma Receiving Tezepelumab: The TezEx Stud
Severe Asthma
2024-12-01
CompletedExploring the User Experience of CGA-Q
CGA, Comprehensive Geriatric Assessment, Person Centred Care
2024-11-04
UnknownBarriers to Rectal Irrigation in Defaecatory Dysfunction
Defecation Disorder, Constipation - Functional, Constipation by Outlet Obstruction
2024-10-01
CompletedUsing AI Within Digital Wound Monitoring of Surgical Wounds to Prioritise Non-healing Wounds for Urgent Review
Surgical Wound, Wound Healing Delayed, Heart; Surgery, Heart, Functional Disturbance as Result
N/A2024-08-24
Not Yet RecruitingPrescription-based Fluid Management Versus Usual Care in Critically Ill Patients on KRT Trial in UK
Acute Renal Failure on Dialysis (Disorder)
N/A2024-08-01
Not Yet RecruitingThe PICM Risk Prediction Study - Application of AI to Pacing
Heart Failure, Pacemaker-Induced Cardiomyopathy, Pacemaker Complication
2024-07-30
Not Yet RecruitingMechanistic Insights From Temporary Pacing in HFpEF
Heart Failure Preserved Ejection Fraction, Pacing
N/A2024-07-01
Not Yet RecruitingLeft Bundle Branch Area Pacing 3D Guidance System
Left Bundle Branch Pacing, Heart Failure, Bradycardia
2024-07-01
Not Yet RecruitingUK ANDROMEDA-Shock-2 RCT
Septic Shock
N/A2024-07-01
Not Yet RecruitingFIBRotic Interstitial Lung Disease With Nocturnal hypOXaemia and EXercise Induced desaTuRAtion
Interstitial Lung Disease, Fibrosis Lung, Pulmonary Hypertension
2024-07-01
Not Yet RecruitingThe A D A G I O Study
Open Angle Glaucoma, Ocular Hypertension
2024-06-01
Not Yet RecruitingICP & Outflow Study
Eye Change, Idiopathic Intracranial Hypertension
2024-06-01
RecruitingThe ReVo Study: Low-volume vs High-volume Rectal Irrigation
Constipation - Functional, Constipation, Constipation by Outlet Obstruction
N/A2024-05-10
Not Yet RecruitingPredicting Outcomes in Atrial Fibrillation and Heart Failure
Atrial Fibrillation, Heart Failure
2024-05-01
RecruitingThe COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls
REM Sleep Behavior Disorder, Concussion, Brain
2024-04-23
Active Not RecruitingRole of 3D Echocardiography Knowledge-based Reconstruction in ACHD
Tetralogy of Fallot
2024-04-11
RecruitingAssessment of Volume-targeted Ventilation in Patients With Neuromuscular Disease
Neuromuscular Diseases
Phase 22024-04-09
Not Yet RecruitingA Prospective Patient Reported Outcomes and Wearables Study in Myeloproliferative Neoplasms
Myeloproliferative Neoplasm
2024-04-01
UnknownDeveloping Better Computerised Vision Tests (CVTV)
Visual Impairment, Amblyopia, Macular Degeneration
2024-04-01
UnknownAssess the Clinical Effectiveness in AI Prioritising CT Heads
Trauma, Brain, Mass Lesion, Skull Fractures
2024-03-27
UnknownIMV to Accelerate Recovery of Lung Function in Veno-venous Extracorporeal Membrane Oxygenation; Lung Rest Or M
ARDS
N/A2024-02-22
RecruitingStudy of Inflammatory and Physiological Profiles of Healthy and Diseased Lung
COPD, Asthma, Airway Disease
2024-02-08
UnknownThe Effect of CRT on the Frank Starling Mechanism
Pacemaker, Heartfailure
N/A2024-01-15
Not Yet RecruitingMBCT-vision VSS RCT
Visual Snow Syndrome
N/A2024-01-01
UnknownObsErvational Study of the Practical Cinical UTility of the NuQ.® H3.1 Nucleosome Levels in Adult Patients Wit
Sepsis
2023-12-18
UnknownDetermination of Utility of Intergluteal Cleft as Landmark for Neuraxial Midline in Obstetrics
Obstetric Anesthesia Problems
2023-12-07
UnknownPhysical Activity and Exercise in Cancer Immunotherapy Treatment
Cancer
2023-12-04
UnknownContinuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Ef
Pleural Effusion
2023-11-15
UnknownVolatile Sedation for Patients With the Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome, Mechanical Ventilation Complication, Sedation Complication
Phase 2 / Phase 32023-11-01
UnknownIn Silico Pace Mapping To Optimise Ventricular Tachycardia Ablation
Ventricular Tachycardia
2023-10-01
Not Yet RecruitingOutcome Prediction in Patients With Aortic Stenosis After TAVI
Aortic Stenosis, Severe
2023-10-01
RecruitingStructured Exercise Versus Endovascular Reconstruction in Post Thrombotic Syndrome
Post Thrombotic Syndrome
N/A2023-09-05
UnknownA Pilot Observational Study to Assess the Ability of Continuous 'Home' EEG to Accurately Diagnose Narcolepsy a
Narcolepsy Type 1, Hypersomnia
2023-09-01
UnknownEvaluation of the Implementation of Personalised Follow-up in Head and Neck Cancer
Head and Neck Cancer
2023-08-08
UnknownImprovement of RARP Outcomes Via 3D Printed/Virtual Prostate Models
Prostate Cancer
N/A2023-07-31
RecruitingBEARS Training Package to Maximise Hearing Abilities in Older Children and Teenagers With Bilateral Cochlear I
Hearing Loss, Sensorineural, Hearing Loss, Deafness
N/A2023-07-27
Active Not RecruitingENHANCE - Evaluating the Implementation of Head and Neck Cancer E-health
Head and Neck Neoplasms
2023-06-14
UnknownArtificial Intelligence Diagnostic Aid
Wet Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion
2023-06-01
UnknownBeyond the Eosinophil: Understanding the Impact of Eosinophil Depletion on T2 Inflammation. (BEUTI)
Asthma
2023-05-22
RecruitingPredicting the Risk of Non-culprit Coronary Artery Disease After a Heart Attack
Coronary Artery Disease, ST Elevation Myocardial Infarction, Ischemic Heart Disease
2023-04-25
CompletedValidating the 'Sexual Minorities and Prostate Cancer Scale' to Gold Standard Questionnaires
Prostate Cancer, Incontinence, Erectile Dysfunction Following Radical Prostatectomy
2023-03-15
UnknownIdentification of Patients at Risk of CKD After AKI
Acute Kidney Injury, Kidney Diseases
2023-03-01
UnknownDetermining Cost of Explant of Neurmodulation Device Due to Infection
Neuropathic Pain, Infections, Device Related Sepsis
2023-03-01
UnknownAchieving Conduction System Activation With Leadless Left Ventricular Endocardial Pacing
Heart Failure
N/A2023-01-01
UnknownPatient Perspectives on Artificial Intelligence in Radiology
Patients Waiting for Radiology Exams
2022-11-01
UnknownComparison of Two Aspheric Intraocular Lenses for Micro-monovision
Cataract, Presbyopia, Pseudophakia
N/A2022-10-01
UnknownComparison of Aspheric Toric Intraocular Lenses for Micro-monovision
Cataract, Presbyopia, Astigmatism
N/A2022-09-01
CompletedComparison of Unilateral CI vs. Bimodal Stimulation in Prosodic Perception
Cochlear Hearing Loss
2022-08-30
UnknownPatient Engagement With Digital Health Tools in Rheumatology
Rheumatic Disease, PROM
2022-07-01
UnknownUse of Alexa as a Cognitive Aid for Emergency Front Of Neck Access (FONA)
Intubation; Difficult or Failed
N/A2022-06-30
UnknownInGReS: Intra-treatment Image Guided Adaptive Radiotherapy Dose-escalation Study
Head and Neck Cancer
N/A2022-06-17
UnknownHaemodynamics of Mitral Regurgitation Reduction
Mitral Regurgitation
2022-06-06
UnknownPROSAIC-DS Study (PROState AI in Cancer - Decision Support)
Prostate Cancer
N/A2022-06-01
UnknownA Longitudinal Study to Analyse the Correlation Between CAI and Bilirubin
Hemolysis Neonatal
2022-06-01
Not Yet RecruitingDual-Energy Computed Tomography for Improving Imaging Assessment of Multiple Myeloma
Myeloma
2022-06-01
UnknownHospital Acquired Pneumonia in Temporary Tracheostomy
Head and Neck Cancer, Tracheostomy Complication, Hospital-acquired Pneumonia
2022-06-01
UnknownSOTO: Treatment Sensitivity of Organoids to Predict Treatment Outcome
Head and Neck Squamous Cell Carcinoma, Head and Neck Cancer
2022-06-01
CompletedMalignant Pleural Effusions: Evaluating the psYchosocial Impact of Indwelling Pleural Catheters on Patients
Malignant Pleural Effusion, Indwelling Pleural Catheter
2022-05-09
UnknownReal World Outcomes Using Novel Agents for AML in the UK
Acute Myeloid Leukemia
2022-05-01
UnknownLeaving Nobody Out
HIV Infections
2022-05-01
UnknownIntra-articular Injection of Lidocaine in Inflammatory Arthritis
Inflammatory Arthritis
N/A2022-04-18
UnknownBOOST Workshop Versus Traditional 1-1 Physiotherapy for Back Pain
Back Pain
N/A2022-04-01
RecruitingThe South London Stroke Register: Improving the Lives of Stroke Survivors With Data
Stroke, Subarachnoid Hemorrhage, Intracranial Hemorrhages
2022-04-01
CompletedRemote Monitoring to Improve Low Adherence in Non-invasive Ventilation
Hypercapnic Respiratory Failure, Sleep Disordered Breathing, COPD
N/A2022-03-28
UnknownSiderophores for Imaging Infection Using 68Ga-DFO
Vascular Graft Infection
2022-03-15
UnknownRemimazolam vs Midazolam Cognitive and Motor Recovery After Intravenous Conscious Sedation for Dental Extracti
Tooth Extraction
Phase 32022-03-09
UnknownImpact of Cold Exposure on Metabolic Regulation in Children With Non Alcoholic Fatty Liver Disease (NAFLD)
Non-Alcoholic Fatty Liver Disease
N/A2021-10-23
RecruitingRate or Rhythm Control in CRT: the RHYTHMIC Study
Atrial Fibrillation, Heart Failure
N/A2021-10-19
Active Not RecruitingUrine Alkalinisation in COVID-19
Covid19, Acute Kidney Injury
N/A2021-10-15
CompletedQuality of Recovery From Obstetric Anaesthesia - a Multicentre Study
Obstetric Anesthesia Problems, Anesthesia Morbidity, Quality of Life
2021-10-11
UnknownHyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage?
Cervical Incompetence in Pregnancy as Antepartum Condition
Phase 42021-08-27
CompletedOptimisation of ASthma In Those With Uncontrolled Symptoms (OASIS)
Asthma, Asthma Attack, Asthma Persistent
N/A2021-08-09
Active Not RecruitingControlled Trial of High-risk Coronary Intervention With Percutaneous Left Ventricular Unloading
Ischemic Heart Disease, Coronary Artery Disease
Phase 32021-08-06
UnknownUrine Alkalinisation to Prevent AKI in COVID-19
Covid19
Phase 32021-07-19
CompletedThinking Outside the Box
Medication Compliance, Medication Adherence, Caregivers
2021-07-07
UnknownLow Intensity Shock-wave Therapy (Li-ESWT) in Penile Rehabilitation After Radical Prostatectomy
Erectile Dysfunction Following Radical Prostatectomy
N/A2021-06-01
UnknownMagnetic Resonance Imaging and Thermal Imaging of Adiposity in Neonates of Women With Metabolic Diseases
Diabetes Mellitus, Intrahepatic Cholestasis of Pregnancy, Metabolic Disease
2021-06-01
SuspendedEfficacy of an Advanced Auto-titrating NIV in COPD
Chronic Obstructive Pulmonary Disease Severe
N/A2021-05-04
UnknownAdjunctive Laser for Periodontal Intrabony Defects
Periodontitis
N/A2021-04-01
UnknownThe MONACO Cell Therapy Study: Monocytes as an Anti-fibrotic Treatment After COVID-19
Pulmonary Fibrosis, Interstitial Lung Disease, Covid19
Phase 1 / Phase 22021-03-08
UnknownAerosolisation During Respiratory Procedures
Healthy, Respiratory Tract Infections, Lung Infection
2021-03-01
UnknownHydroxychloroquine in ANCA Vasculitis Evaluation
ANCA Associated Vasculitis, Microscopic Polyangiitis, Churg-Strauss Syndrome
Phase 42020-12-17
CompletedAccuracy of Peak Cough Flow Measurements Using a Mechanical Insufflator-exsufflator
Neuromuscular Diseases
2020-12-04
UnknownAtrial CMR in Patients With CVA of Unknown Source and no Known AF
Stroke, Ischemic, Atrial Fibrillation
2020-10-01
CompletedVitamin D Status and Immune-inflammatory Status in Different UK Populations With COVID-19 Infection
Covid19
2020-09-01
UnknownAKI Biomarkers in Coronavirus(COVID)-19
COVID, Acute Respiratory Failure, Acute Kidney Injury
2020-08-20
UnknownEndothelial Function, Inflammation and Organ Dysfunction in COVID-19
COVID, Shock
2020-08-05
UnknownStudy of the Treatment and Outcomes in Critically Ill Patients With COVID-19 and High Risk of Acute Kidney Inj
COVID, Acute Kidney Injury, Critical Illness
2020-06-20
UnknownEfficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Dis
COVID, Acute Respiratory Distress Syndrome
2020-06-01
CompletedStudy for Testing and Reviewing Improvised PPE Effectiveness 3 (STRIPE-3)
Healthy
2020-05-01
UnknownComparing the Effectiveness of Phacoemulsification + ECP Laser and Phacoemulsification Alone for Glaucoma Pati
Glaucoma Open-Angle Primary, Cataract
Phase 42020-03-15
UnknownPD-L1 Expression in Cancer (PECan Study).
Non-small Cell Lung Cancer, Melanoma
N/A2020-03-11
UnknownOn the Road to Recovery After Critical Illness
Post Intensive Care Syndrome
N/A2020-02-26
CompletedLubricating Eye Drops After Routine Cataract Surgery
Dry Eye, Cataract
N/A2020-02-24
CompletedPersonalised Simulation Technologies for Optimising Treatment in the Intensive Care Unit
Respiratory Distress Syndrome, Adult, Respiratory Insufficiency
2020-02-20
CompletedPregnancy Dating Test - The Fall of hPL in Urine Over Time
Abortion, Complete, Miscarriage Threatening
2020-02-19
UnknownSphingosine-1-phosphate in Asthma
Asthma
N/A2020-02-04
UnknownMinimally-invasive Non-surgical Treatment in Teeth With Unfavourable Prognosis
Periodontitis
N/A2020-02-01
CompletedMindfulness Based Cognitive Therapy Modified for Visual Symptoms (MBCT-vision)
Visual Snow Syndrome, Trailing Phenomenon, Photophobia
N/A2020-01-09
UnknownInvestigating Health Related Quality of Life in Patients With Chronic Respiratory Failure
Chronic Obstructive Pulmonary Disease, Respiratory Failure, Neuromuscular Diseases
2019-12-19
UnknownOptimisation of Mechanical Insufflation:Exsufflation
Neuromuscular Diseases
N/A2019-12-19
UnknownAppointment Intervals and Orthodontic Tooth Movement
Orthodontic Treatment
N/A2019-12-01
UnknownReliability of Functional Outcome Measures in Neurofibromatosis 1: Test- Retest
Neurofibromatosis Type 1
2019-11-30
CompletedMicronutrients in Critically Ill Patients
Nutrition, Critical Illness, Vitamin Supplementation
2019-11-18
CompletedPOWER: PrehabilitatiOn Workshop and Mentored Exercise Programme in Patients Having Elective Aortic Aneurysm Re
Vascular Surgery
N/A2019-11-15
CompletedHow do Individuals Respond to a Diagnosis of 3PD
Persistent Postural Perceptual Dizziness, Vestibular Disease, Chronic Dizziness
2019-11-08
CompletedNAVA in Infants With Acute Viral Bronchiolitis: A Feasibility Study
Acute Viral Bronchiolitis
N/A2019-11-05
UnknownUse of Prophylactic Lubricating Drops After Cataract Surgery
Dry Eye, Cataract Surgery, Patient Related Outcome Measures
N/A2019-10-14
UnknownPosterior Capsular Opacification and Glistenings in Hydrophobic and Hydrophilic Intraocular Lenses
Cataract, Intraocular Lens Opacification
N/A2019-10-14
UnknownToric Intraocular Lenses for Cataract Patients in the NHS
Cataract, Astigmatism, Cornea
N/A2019-10-14
UnknownCerclage After Full Dilatation Caesarean Section
Preterm Birth, Preterm Premature Rupture of Membrane, Preterm Spontaneous Labor With Preterm Delivery
N/A2019-10-02
WithdrawnFactors Affecting Outcome of Vestibular Rehabilitation
Chronic Dizziness, Vestibular Disease
2019-09-26
UnknownEXERT: Exercise Physiology After Thrombosis
Venous Thrombosis Deep (Limbs), Post Thrombotic Syndrome
2019-09-20
Active Not RecruitingProstate Cancer Active Surveillance Trigger Trial (PCASTT-UK): Comparing Current Practice for Men With Prostat
Prostate Cancer
N/A2019-09-19
UnknownCardiac Resynchronisation Therapy In Patients With Heart Failure: Mechanistic Insights From Cardiac MRI And El
Heart Failure
N/A2019-09-01
RecruitingA Prospective Randomised Multi-centre Trial Comparing cArdiac MRI Guided CRT Versus Conventional CRT Implantat
Cardiovascular Diseases
N/A2019-07-05
UnknownInvestigation of the Faecal Loss of Vedolizumab and Its Role in Influencing Serum Drug Levels, Outcomes and Re
Ulcerative Colitis
Phase 42019-07-01
UnknownPathophysiology of Hypoventilation in Obesity and Effects of Bariatric Intervention
Obesity Hypoventilation Syndrome (OHS)
2019-06-20
CompletedThe Role of HNHF to Improve Clinical Outcomes Following Severe AECOPD
Chronic Obstructive Pulmonary Disease
N/A2019-06-17
UnknownUnderstanding Abdominal Pain in IBD and IBS
Abdominal Pain, Inflammatory Bowel Diseases, Irritable Bowel Syndrome
2019-05-20
UnknownTAPS2 Transfusion Antenatally in Pregnant Women With SCD
Sickle Cell Disease, Pregnancy, High Risk, Blood Transfusion Complication
Phase 22019-05-02
UnknownContemporary Endovascular Therapies in Treatment of Acute Iliofemoral Deep Vein Thrombosis
Thrombolysis, Deep Vein Thrombosis
2019-03-29
UnknownImproving Treatment of Glioblastoma: Distinguishing Progression From Pseudoprogression
Glioblastoma
2019-03-21
CompletedPercutaneous Mitral Valve Intervention: Predicting Improvements in Left Ventricular Performance
Mitral Regurgitation, Mitral Valve Insufficiency
2019-03-20
TerminatedIdentifying Biomarkers and Changes in Cerebrospinal Fluid Collected Pre and Post Spinal Cord Stimulation in Su
Neuropathic Pain
N/A2019-03-19
UnknownA Study Into the Future Cardiovascular Disease (CVD) Risk of Phenylketonuria (PKU) Patients on a Low Phenylala
Phenylketonurias, Cardiovascular Diseases
2019-02-23
CompletedExercise Intervention for Sleep in Neurodevelopmental Disorders
Neurodevelopmental Disorders, Sleep Disorder
2019-02-14
UnknownPreoperative Paravertebral Block in Cancer Surgery of the Lung
Thoracic Neoplasm, Chronic Pain Post-Procedural, Acute Post-thoracotomy Pain
Phase 2 / Phase 32019-02-01
UnknownElectrocochleography Function for Monitoring Residual Hearing
Hearing Loss, Cochlear
N/A2019-01-24
CompletedCleft Palate Surgical Simulator: Improvement in Surgical Trainees' Knowledge and Confidence.
Cleft Palate Lip
N/A2019-01-01
CompletedFIBRotic Interstitial Lung Disease and Nocturnal OXygen
Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea, Sleep Disturbance
2018-12-17
UnknownPromote Food. Improving Food-related Quality of Life in Inflammatory Bowel Disease
Quality of Life, Inflammatory Bowel Diseases
N/A2018-12-16
CompletedOesophageal Acid Exposure in Healthy Subjects Over 96 Hours
Gastroesophageal Reflux
N/A2018-10-16
CompletedThe Grown Up Peanut Immunotherapy Study
Peanut Allergy
N/A2018-10-15
CompletedCT Guided WiSE-CRT
Heart Failure
N/A2018-08-31
UnknownDRy Eye Outcome and Prescription Study
Dry Eye, Dry Eye Syndrome, Blepharitis
2018-08-23
TerminatedSham-Controlled RCT on 10kHz High-Frequency Spinal Cord Stimulation for Chronic Neuropathic Low Back Pain (Mod
Chronic Low Back Pain, Neuropathic Pain, Refractory Pain
N/A2018-08-14
CompletedPneumococcal Vaccination to Accelerate Immune Recovery in Sepsis Survivors
Sepsis
Phase 42018-08-02
UnknownA Study to Investigate the Effect of HMB on Skeletal Muscle Wasting in Early Critical Illness
Critical Illness
Phase 22018-06-18
CompletedDomiciliary Transcutaneous Electrical Stimulation in Obstructive Sleep Apnoea
Obstructive Sleep Apnea
N/A2018-06-18
TerminatedTransGrade Multimodal Neuromodulation of the Dorsal Root Ganglion Ensemble for Refractory Neuropathic Pain
Neuropathic Pain, Pain, Chronic
N/A2018-06-12
CompletedStructured Light Plethysmography in Obstructive Airways Disease
Pediatric Respiratory Diseases
2018-06-11
UnknownPersonalised Responses to Dietary Composition Trial
Diabetes, Heart Diseases, Diet Habit
N/A2018-06-04
WithdrawnEffect of PEEP on Lung Recruitment and Homogeneity Over Time in Moderate to Severe ARDS
ARDS, Critical Illness, Ventilator-Induced Lung Injury
2018-06-01
UnknownBalloon Inflation and Plaque Morphology in Revascularisation (BURST)
Coronary Artery Disease, Atherosclerosis
2018-06-01
UnknownOmega 3 and Fibre Intervention Study to Improve Metabolic Health
Metabolic Disease, Immune Function, Cardiovascular Diseases
N/A2018-05-31
WithdrawnA Trial of Mindfulness Meditation for Chronic Insomnia
Insomnia
N/A2018-05-01
CompletedHOT HMV 2: A Phase 4 Study
COPD Exacerbation
2018-05-01
CompletedCYPHP Evelina London Evaluation
Asthma, Eczema, Constipation
N/A2018-04-09
CompletedOSA Recurrence in CPAP Withdrawal
OSA
N/A2018-04-09
UnknownComparison of Efficacy of Three Orthodontic Appliances
Malocclusion, Angle Class II
N/A2018-04-01
UnknownOverhead Perturbation Training for Glenohumeral Joint Instability
Exercise Movement Techniques, Shoulder Pain, Glenohumeral Subluxation
N/A2018-04-01
CompletedXPAND Trial: Enhancing XP Photoprotection Activities - New Directions
Xeroderma Pigmentosum
N/A2018-03-30
CompletedCorrelations Between Wireless pH Monitoring and Variation in Reflux Symptom Questionnaire, 7 Day Recall
Gastroesophageal Reflux
2018-03-20
UnknownRadiofrequency Ablation vs Sham Procedure for Symptomatic Cervical Inlet Patch
Barrett Esophagus
N/A2018-03-06
CompletedPhysiological Predictors of Clinical Outcomes After Anti-reflux Surgery
Gastroesophageal Reflux
2018-03-05
CompletedNRD to Predict COPD Exacerbations at Home
Chronic Obstructive Pulmonary Disease
2018-02-13
CompletedA Study Comparing Two Monofocal, Aspheric, Hydrophobic Acrylic Intraocular Lenses: the Alcon CLAREON® and the
Cataract Extraction, Phacoemulsification, Glistenings
N/A2018-02-06
CompletedA Randomised Trial of Expedited Transfer to a Cardiac Arrest Centre for Non-ST Elevation Out-of-hospital Cardi
Out-Of-Hospital Cardiac Arrest
N/A2018-02-02
UnknownMonitoring Ovarian Cysts in Pregnancy
Ovarian Cysts
2018-02-01
UnknownTrial of Cardiac CT in Acute Chest Patients With Intermediate Level Initial High-sensitivity Cardiac Troponin
Chest Pain, Coronary Artery Disease, Acute Coronary Syndrome
N/A2018-01-12
CompletedThe Role of Home Packs of HIV PEPSE in High Risk Individuals
HIV-1-infection
Phase 42018-01-01
UnknownMinimally Invasive Kidney Transplantation
Transplant;Failure,Kidney
2017-12-01
UnknownAnalysis of the Variation in Caspase-8 Availability and Cleavage in Oral Squamous Cell Carcinoma
Oral Cancer
2017-11-11
UnknownMotivating Structured Walking Activity in Intermittent Claudication
Peripheral Arterial Disease, Intermittent Claudication, Peripheral Vascular Disease
N/A2017-11-10
CompletedPatient Experience of Acute Rehabilitation After Hip Fracture
Hip Fractures, Fracture of Hip, Fractured Hip
2017-10-06
UnknownPatient Reported Outcomes Following Parotid Resections
Parotidectomy, Patient-reported Outcomes
2017-10-01
CompletedTime to Protection and Adherence Requirements of Raltegravir With or Without Lamivudine in Protection From HIV
Hiv
Phase 42017-09-19
CompletedStudy of the Golimumab Exposure-Response Relationship Using Serum Trough Levels
Ulcerative Colitis
Phase 42017-09-05
UnknownINTERVAL - Intense Exercise Trial for Men With Metastatic Castrate-Resistant Prostate Cancer
Prostate Cancer
N/A2017-09-01
UnknownThe Effectiveness of Electronic Reminders in Improving Elastic Compliance in Orthodontic Patients
Malocclusion, Compliance, Patient
N/A2017-07-01
CompletedClearance of Inflammatory Cytokines During Renal Replacement Therapy Using the EMIC®2 Filter
Acute Renal Failure
2017-07-01
CompletedThe Use of Computed Tomography (CT) to Measure Skeletal Muscle Quantity and Quality in Patients Receiving ECMO
Critical Illness, Muscle Atrophy
2017-06-20
CompletedBond Failure of Two Types of Molar Buccal Tubes
Orthodontic Appliance Complication
N/A2017-05-08
CompletedProof of Concept Study for a Dressing Glove
Epidermolysis Bullosa Dystrophica
2017-05-03
UnknownInfluence of Body Positioning on the Identification of Tuffier's Line Using the Palpation Method: An Ultrasoun
Pregnant Women
2017-04-14
UnknownMR-simulation in Radiotherapy for Prostate Cancer
Cancer of the PROSTATE
N/A2017-03-01
CompletedThe Relationship Between Arterial Stiffness and Respiratory Failure in Motor Neurone Disease
Motor Neurone Disease, Hypoxemia and/or Hypercapnia
2017-02-21
UnknownPaternally Inherited Phenotypes in Cholestasis
Cholestasis, Primary Sclerosing Cholangitis, Primary Biliary Cirrhosis
2017-02-08
UnknownPre-pectoral Breast Reconstruction PART 2
Breast Cancer
Phase 32017-01-01
UnknownPre-pectoral Breast Reconstruction PART 1
Breast Cancer
Phase 32017-01-01
CompletedA Comparison of the VBM Intubating Laryngeal Tube and the I-Gel
Airway Management
N/A2017-01-01
UnknownTissue Stresses of Cancer (Force Horizon 2020)
Breast Cancer Female
Phase 1 / Phase 22016-11-01
CompletedCharacterising Changes in Muscle Quantity and Quality in Patients Requiring ECMO Oxygen During Critical Illnes
Critical Illness, Intensive Care Units, Extracorporeal Membrane Oxygenation
2016-11-01
UnknownPrehabilitation of Patients With oEsophageal Malignancy Undergoing Peri-operative Treatment
Oesophageal Adenocarcinoma, Chemotherapy Effect, Surgery
N/A2016-11-01
CompletedReliability of Functional Outcome Measures in Neurofibromatosis 2
Neurofibromatosis 2
2016-09-07
CompletedSymptomatic Treatment of Excessive Dynamic Airway Collapse Using Daytime Portable Continuous Positive Airway P
Excessive Dynamic Airway Collapse, Tracheobronchomalacia
N/A2016-09-01
UnknownSurgical Approaches in Treating Uncontrolled Glaucoma in Black African and African-Caribbeans
Primary Open Angle Glaucoma
N/A2016-08-01
CompletedFemtosecond Laser Assisted Cataract Surgery in The NHS
Cataract, Surgery
N/A2016-08-01
CompletedChanges in Regional Lung Ventilation Following Mechanical Insufflation-Exsufflation
Neuromuscular Diseases
N/A2016-08-01
CompletedThe Feasibility of Measuring Energy Expenditure During Physical Rehabilitation In Critically Ill Patients
Intensive Care
2016-07-01
UnknownAqueous Dynamics and Glaucoma Surgeries
Glaucoma, Ocular Hypertension
2016-07-01
UnknownLabour Epidural Top-up With Warmed Ropivacaine
Epidural Top-up, Labour, Caesarian Section
N/A2016-07-01
UnknownCT Colonography as the Initial Diagnostic Imaging Tool for Patients With Suspected Colorectal Cancer
Colorectal Cancer
2016-06-14
UnknownThe Use of MRI in the Assessment of Suspected Scaphoid Fracture With Negative Findings on the Initial Plain Ra
Scaphoid Fracture
N/A2016-06-06
CompletedEIT Study With COPD and OHS Patients (EIT Step 2)
OHS, COPD
N/A2016-05-01
CompletedVitamin D in Critically Ill Patients With Acute Kidney Injury
Acute Kidney Injury
2016-04-01
CompletedPET/MR in Radiotherapy for Head and Neck Cancer Pilot
Head and Neck Cancer
N/A2016-04-01
CompletedEIT Study With Healthy Patients
Healthy Participants
Phase 12016-04-01
CompletedEvaluating Thromboelastography (TEG) and ETP in Sickle Adults
Sickle Cell Disease
2016-04-01
UnknownDirect Access to MRI and Neurology Referrals for the Management of Patients With Chronic Headache.
Chronic Headache
2016-04-01
CompletedEvaluation of Electrical Impedance Tomography for the Diagnosis of Chronic Rejection in Lung Transplants Recip
Transplantation, Heart-Lung, Chronic Lung Allograft Dysfunction, Bronchiolitis Obliterans Syndrome
N/A2016-04-01
CompletedEMG in COPD - Factor Analysis
COPD
2016-01-01
UnknownPrevalence of COPD in Our Lung Cancer Population, Compared to Controls
COPD, Lung Cancer, Smoking
2015-12-01
UnknownFeasibility Studies to Inform Novel Proposals to Avert Community-Based Antimicrobial Resistance Spread
Gram-Negative Bacterial Infections
2015-12-01
UnknownHEAD-US SCORING SYSTEM: Assessment of the Real-world Impact of Ultrasound
Moderate and Severe Haemophilia
N/A2015-12-01
CompletedECCO2R as an Adjunct to NIV in AECOPD
Chronic Obstructive Pulmonary Disease
N/A2015-12-01
CompletedVitamin D and Immunity: Photosynthesis Versus Supplementation
Vitamin D Deficiency
N/A2015-11-19
TerminatedPilot Study to Test the Feasibility of the Use of MRI in Suspected Scaphoid Fractures
Scaphoid Fracture
Phase 32015-11-01
CompletedCardiac and Respiratory Function With Non-invasive Ventilation
OHS, Hypercapnic Respiratory Failure
2015-11-01
WithdrawnBlood/Urine Markers for Drug Discovery for Renal Disease in Diabetes
Diabetes Complications
2015-09-01
UnknownStandard Care Versus Triventricular Pacing in Heart Failure
Heart Failure
Phase 32015-08-01
CompletedOut Patient Talc Slurry Via Indwelling Pleural Catheter for Malignant Pleural Effusion Vs Usual Inpatient Mana
Pleural Effusion, Malignant
N/A2015-08-01
UnknownMetformin And Longevity
Prostate Cancer
Phase 42015-07-01
CompletedReliability of Functional Outcome Measures in Neurofibromatosis 1
Neurofibromatosis 1, NF1
2015-06-01
UnknownVitamin K as Additive Treatment in Osteoporosis
Post-menopausal Osteoporosis
Phase 2 / Phase 32015-04-01
UnknownSelective Coronary Vein Sampling in Left Bundle Branch Block and CRT
Heart Failure
N/A2015-04-01
TerminatedA Multicentre randomiSed Controlled TRial of IntraVEnous Immunoglobulin Versus Standard Therapy for Transverse
Myelitis, Transverse, Neuromyelitis Optica
Phase 32015-03-01
CompletedCost Effectiveness of Outpatient Set-up of Automated NIV in Obese Patients With Chronic Respiratory Failure
Obesity Hypoventilation Syndrome, Chronic Respiratory Failure
Phase 32015-03-01
UnknownBile Acid Effects in Fetal Arrhythmia Study
Cholestasis of Pregnancy, Intrahepatic Cholestasis of Pregnancy, Obstetric Cholestasis
2015-02-27
UnknownGenetic Predictors of Responsiveness to Radiofrequency Denervation in Chronic Low Back Pain
Chronic Low Back Pain
2015-02-01
CompletedIntermittent Versus Continuous Feeding in ICU Patients
Intensive Care (ICU) Myopathy
Phase 22015-02-01
CompletedPSG Versus Oxim-capnography to Setup Home NIV
COPD, OSA
Phase 22015-01-01
CompletedRole of Anti-IgE in Severe Childhood Eczema
Atopic Eczema, Atopic Dermatitis, Child
Phase 42014-12-01
CompletedOutcome After 24 Months of Participants in the TOBY Xenon Study
Perinatal Asphyxia, Encephalopathy
2014-08-01
CompletedEffect of Citrate on the Coagulation System in Patients Receiving CRRT
Acute Kidney Failure
2014-06-01
CompletedSafety and Efficacy Study of Regulatory T Cell Therapy in Liver Transplant Patients
End-stage Liver Disease
Phase 1 / Phase 22014-06-01
CompletedThe ONE Study UK Treg Trial
End-stage Renal Failure
Phase 1 / Phase 22014-04-01
TerminatedCRT In Narrow QRS Heart Failure: Mechanistic Insights From Cardiac MRI And Electroanatomical Mapping
Heart Failure
N/A2014-04-01
UnknownFibrillatory Factor in Ventricular Tachycardia
Ventricular Tachycardia
N/A2013-11-01
CompletedAqueous Humor Dynamics and Hypertensive Uveitis
Uveitic Glaucoma, Anterior Uveitis
2013-08-01
CompletedEssential Nutrients in Critically Ill Patients With Severe AKI Treated With and Without CRRT
Acute Kidney Failure
2013-08-01
Active Not RecruitingImmune Function in Acute Kidney Injury
Acute Kidney Failure
2013-06-01
CompletedContinuous Transcutaneous Electrical Stimulation in Sleep Apnoea
Obstructive Sleep Apnoea
N/A2013-03-01
Completed18F-FDG-PET Guided Dose-Painting With Intensity Modulated Radiotherapy in Oropharyngeal Tumours
Oropharyngeal Cancer
Phase 12013-02-01
CompletedFeasibility And Efficacy Of Continuous In-Hospital Patient Monitoring
Monitoring of Patients Following Surgery
N/A2012-12-01
UnknownThe Use of Subcutaneous Implantable Cardiac Defibrillators (ICDs) Following Extraction of Conventional ICDs
Use of Subcutaneous ICDs Following Infection
N/A2012-11-01
UnknownPressure Wire Guided Cardiac Resynchronisation Therapy
Heart Failure
Phase 2 / Phase 32012-09-01
WithdrawnRopivacaine 0.75% Versus Levobupivacaine 0.5% for Conversion of Labour Epidural
Caesarean Section
Phase 42012-08-01
CompletedProphylaxis Of Wound Infections- Antibiotics in Renal Donation
Infection
Phase 42012-07-01
CompletedValidation of Respiration Rate Algorithms
Respiratory Rate, Pulse Oximetry
2012-06-01
CompletedA Study to Investigate the Effects of Heated Humidification During Non-Invasive Ventilation
Chronic Obstructive Pulmonary Disease, Chronic Respiratory Hypercapnic Failure, Neuromuscular Disease
N/A2012-02-01
CompletedDoes Adding Milk to Tea Delay Gastric Emptying?
Gastric Emptying
N/A2011-11-01
CompletedA Trial of Rehabilitation in Obesity Hypoventilation Syndrome (OHS)
Obesity Hypoventilation Syndrome
N/A2011-11-01
UnknownPRISM Cardiac Resynchronisation Therapy (CRT) Randomised Controlled Trial
Heart Failure
Phase 2 / Phase 32011-10-01
CompletedThe Post-Operative Pain in Cerebral Palsy (POPPIES) Trial
Cerebral Palsy, Post-operative Pain
Phase 32011-10-01
CompletedMyotrace: An Evaluation of a Novel Critical Illness Monitoring System
Chronic Obstructive Pulmonary Disease
2011-01-01
UnknownRituxiMab INDuction in Renal Transplantation
Function of Renal Transplant
Phase 42010-11-01
CompletedAssessment of Gastro-esophageal Reflux Using Endo-Flip vs Bravo
Heartburn, Gastro-esophageal Reflux
2010-09-01
CompletedRehabilitation Following Critical Illness
Critical Illness Myopathy
N/A2009-11-01
UnknownComparison of Pressure Support and Pressure Control Ventilation in Chronic Respiratory Failure
COPD, Chest Wall Disease, Neuromuscular Disease
Phase 42009-08-01
CompletedPrimary Angle Closure Glaucoma and Aqueous Dynamics
Primary Angle Closure
N/A2008-07-01
TerminatedvMII for Measurement of Oesophageal Bolus Transport and Reflux
Achalasia, GORD
N/A2007-11-01
CompletedCoordination Versus Pressure in Oesophageal Peristalsis
Gastroesophageal Reflux
2007-10-01
CompletedMycophenolate Mofetil in Systemic Lupus Erythematosus (MISSILE)
Systemic Lupus Erythematosus, Atherosclerosis
Phase 42006-03-01