NCT05659680

Achieving Conduction System Activation With Leadless Left Ventricular Endocardial Pacing

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (estimated)
• Sponsor: Guy's and St Thomas' NHS Foundation Trust · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this prospective non-randomised study is to test the feasibility of leadless conduction system pacing using the WiSE-CRT device in patients with an indication for Cardiac Resynchronisation Therapy. The main question\[s\] it aims to answer are: 1. What is the safety profile of leadless conduction system pacing? 2. What is the success rate of leadless conduction system pacing? 3. What are the electrical and haemodynamic effects of leadless conduction system pacing. Participants will undergo pre-procedural cardiac CT, and post-procedure electro-anatomical mapping and haemodynamic assessments.

Conditions

• Heart Failure

Interventions

Type	Name	Description
DEVICE	WiSE-CRT	Participants undergo pre-procedural CT, implantation of the WiSE-CRT system targeting the left bundle branch area, and post procedural non-invasive electro-anatomical mapping using electrocardiographic imaging and haemodynamic assessment.

Timeline

• Start date: 2023-01-01
• Primary completion: 2024-07-01
• Completion: 2025-01-01
• First posted: 2022-12-21
• Last updated: 2022-12-21