Trials / Completed
CompletedNCT03648320
The Grown Up Peanut Immunotherapy Study
A Single Arm Phase II Efficacy Study of Peanut Oral Immunotherapy in Adults
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 33 (actual)
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust · Academic / Other
- Sex
- All
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
To determine efficacy and safety of peanut oral immunotherapy in adults with peanut allergy.
Detailed description
25 adults with peanut allergy, as confirmed by double blind placebo controlled food challenge (DBPCFC), will undergo peanut oral immunotherapy (OIT) with peanut flour. An additional 15 untreated peanut allergic adults will be recruited as comparator group for skin prick tests and mechanistic studies/immunological assays.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Peanut oral immunotherapy | Daily doses of peanut flour (with 2-weekly incremental interval) |
Timeline
- Start date
- 2018-10-15
- Primary completion
- 2021-05-21
- Completion
- 2022-05-19
- First posted
- 2018-08-27
- Last updated
- 2024-05-29
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT03648320. Inclusion in this directory is not an endorsement.