Clinical Trials Directory

Trials / Sponsors / UNC Lineberger Comprehensive Cancer Center

UNC Lineberger Comprehensive Cancer Center

Academic / Other · 403 registered clinical trials93 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingArtificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation
Cancer, Prostate Cancer
N/A2026-07-01
SuspendedDara-RVd Induction for Newly Diagnosed Multiple Myeloma With Autologous Stem Cell Transplantation
Newly Diagnosed Multiple Myeloma, Multiple Myeloma, Autologous Stem Cell Transplantation
Phase 22026-07-01
Not Yet RecruitingThe PharmFIT Study
Colorectal Cancer
N/A2026-07-01
Not Yet RecruitingIncorporating Biometric Data for Patients Receiving Concurrent Chemotherapy & RT
Cancer
2026-05-15
Not Yet RecruitingH&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, H
Oral Cavity Squamous Cell Carcinoma, Head and Neck Cancer
Phase 22026-05-01
Not Yet RecruitingSURGIMEDIA: Utilization of Multimedia for Enhanced Surgical Consent
Pancreas Cancer
N/A2026-05-01
Not Yet RecruitingStudy on Treatment Outcome Patterns for Patients With CLL After Discontinuation of BTK Inhibitors
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Phase 22026-05-01
Not Yet RecruitingEvaluation of Impact of AI Assistance on Workload Associated w Preparation of Rare Tumor Case Repts
Cognitive Burden, Cognitive Symptom
N/A2026-05-01
Not Yet RecruitingTirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer
Endometrial Cancer, Endometrial Intraepithelial Neoplasia, Grade 1 Endometrial Endometrioid Carcinoma
Phase 22026-04-01
Not Yet RecruitingC-3002: Enhancing Cervical Cancer Screening Access and Follow-up Care at 'CASCADE' Clinical Sites in the Unite
Human Immunodeficiency Virus (HIV), Human Papillomavirus (HPV), Cervical Cancer
2026-04-01
Not Yet RecruitingUniting Trusted Community Messengers to Improve Access to Cervical Cancer Screening in Rural North Carolina
Cervix Cancer, Screen HPV-positive
N/A2026-04-01
Not Yet RecruitingLocal Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Sp
Thoracic Neoplasms, Lumbar Neoplasm
2026-03-20
RecruitingHomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Sy
Down Syndrome, Child Obesity
N/A2026-03-01
Not Yet RecruitingVirtual Testis Cancer Lay Support and Survivorship Aim 2
Testicular Cancer, Testis Cancer
N/A2026-03-01
Not Yet RecruitingOvercoming Barriers to Uptake of Cascade Screening
Lynch Syndrome
N/A2026-03-01
Not Yet RecruitingPreoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Tri
Breast Cancer, Triple Negative Breast Cancer (TNBC), HER2-Negative Breast Carcinoma
Phase 22026-03-01
RecruitingPREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease
Breast Cancer, Residual Disease, Triple Negative Breast Cancer (TNBC)
Phase 22026-02-26
Not Yet RecruitingTrial of a Personalized and Adaptive Neoantigen Dose-Adjusted Vaccine Concurrently With Pembrolizumab
Squamous Cell Lung Cancer, Squamous Non-small Cell Lung Cancer, Squamous Cell Carcinoma of Head and Neck
Phase 12026-02-22
RecruitingEvolutionary Clinical Trial for Novel Biomarker-Driven Therapies
Breast Cancer, Metastatic Breast Cancer, Triple Negative Breast Cancer
Phase 22026-02-16
RecruitingClinic vs Clinic+Community Outreach HPV Self-Collection to Increase Cervical Screening in Women With HIV
Cervix Cancer, HIV Infections, HPV Infection
N/A2026-02-03
RecruitingHyaluronic Acid-based Gel Spacers in Gynecologic Malignancies
Cervix Cancer
Phase 12026-02-02
Not Yet RecruitingTirzepatide in Obesity-Driven Endometrial Cancer
Endometrial Cancer, Obesity
EARLY_Phase 12026-02-01
RecruitingSparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia
Head and Neck Cancer
Phase 22026-01-28
RecruitingNutrition Awareness Among Women With Non-Metastatic Breast Cancer
Breast Cancer, Breast Cancer Metastatic
N/A2026-01-20
RecruitingFeasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase Exercise
Breast Cancer, Metastatic Breast Cancer
N/A2025-12-15
RecruitingMedically Tailored Meals for Kids
Pediatric Cancer
N/A2025-11-25
RecruitingTranslation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging
Breast Cancer, Kidney Neoplasms, Liver Neoplasms
Phase 22025-11-04
RecruitingUsing Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivo
Obesity, Cancer, Physical Activity
N/A2025-10-27
RecruitingConsumer Perceptions of Alcoholic Beverages
Health Behavior
N/A2025-10-10
RecruitingDissemination of BREASTChoice AIM1-B
Breast Cancer, Breast Neoplasms
N/A2025-10-01
RecruitingPerceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults
Vaping
N/A2025-10-01
RecruitingMolecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Brea
Breast Cancer, Lymph Node Metastasis
N/A2025-08-22
WithdrawnSparing Parotid Ducts Via MRI Sialography for Reduced Patient Reported Xerostomia
Oropharynx Cancer, Head and Neck Cancer, Xerostomia
N/A2025-08-08
RecruitingExpanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes
Cancer, Diabetes
N/A2025-07-03
RecruitingPROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival
Solid Tumor Malignancies, Metastatic Cancer, Breast Cancer
N/A2025-06-27
Active Not RecruitingmPATH-Cloud for Colorectal Cancer Screening
Colorectal Cancer
N/A2025-06-24
RecruitingXL092 and Cemiplimab in BRAF WT Thyroid Cancer
Anaplastic Thyroid Cancer, Thyroid Cancer, BRAF Mutation-Related Tumors
Phase 12025-06-03
RecruitingCombating Cancer-Related Fatigue: A Personalized Supportive Care Program
Indolent Lymphomas, Lymphoma, Chronic Lymphocytic Leukemia
N/A2025-06-03
RecruitingImplementation of an Oral Chemotherapy Adherence Intervention
Solid Tumor, Hematologic Malignancy
N/A2025-05-28
RecruitingMemantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline Dur
Breast Cancer, Locally Advanced Breast Cancer, Cognitive Impairment
Phase 22025-05-07
RecruitingDesigning Visual Tools to Enhance Cancer Surgeon Decision-making
Prostate Cancer, Kidney Cancer
N/A2025-04-24
CompletedPiloting a Reinforcement Learning Tool for Individually Tailoring Just-in-time Adaptive Interventions
Overweight and Obesity, Overweight, Obesity
N/A2025-04-12
RecruitingDigital Art Therapy for Young Cancer Survivors
Cancer, Pediatric Cancer, Pediatric Malignancies
N/A2025-04-07
RecruitingVisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biom
Breast Cancer
2025-03-07
RecruitingEffectiveness of Central Oncology Navigation and the Use of an ORN
Cancer, Malignant Tumor
N/A2025-03-03
RecruitingUltra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-S
Breast Cancer, Early-stage Breast Cancer, Ductal Carcinoma in Situ
Phase 22025-02-19
RecruitingBasal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel
Pancreatic Adenocarcinoma, Metastatic Pancreatic Cancer, Basal Cell Neoplasm
Phase 1 / Phase 22025-02-06
Active Not RecruitingFeasibility of Intravaginal Artesunate as Adjuvant HPV & Cervical Precancer Treatment in Kenya
Human Immunodeficiency Virus, Human Papillomavirus, Cervical Precancer
Phase 22025-01-22
RecruitingRehabilitation Outcomes Study
Cancer, Malignant Tumor
N/A2025-01-21
WithdrawnImmune Reconstitution Monitoring and Pneumococcal Vaccination in Patients Treated With CAR-T Cells
Malignancy, Cancer, Hematological Malignancies
Phase 1 / Phase 22025-01-20
RecruitingPromoting Resilience in Women With Breast Cancer (PRISM -MBC)
Breast Cancer, Metastatic Breast Cancer
N/A2025-01-01
Enrolling By InvitationStreamlined Resin Y90 Radiation Segmentectomy for Small HCC
Hepatocellular Carcinoma (HCC)
2024-11-06
CompletedVisR for Noninvasively Interrogating Stromal Collagen Organization as a Breast Cancer Biomarker: Evaluation of
Breast Cancer
2024-10-16
RecruitingMultimedia Aid for Genetic Testing in Gynecologic Oncology
Ovary Cancer, Endometrial Cancer
N/A2024-10-10
RecruitingBREAST Choice Decision Tool R21 - AIM2
Breast Cancer
N/A2024-10-10
RecruitingA Novel Approach Utilizing Organ Specific Age Proteomics
Breast Cancer
2024-10-10
CompletedEffective Ads for Quitting Smoking
Smoking Behaviors
N/A2024-09-05
Active Not RecruitingPhysical Activity Centers Empowerment
Colorectal Neoplasms
N/A2024-08-14
CompletedLittle Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Eye Tracking
Tobacco Use
N/A2024-08-14
RecruitingAutologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells
Ovary Neoplasm, Ovarian Cancer, Epithelial Ovarian Cancer
Phase 12024-07-29
RecruitingAutologous CAR-T Cells Targeting B7-H3 in PDAC
Pancreas Cancer, Relapse, Resistant Cancer
Phase 12024-07-18
CompletedLittle Cigar and Cigarillo Warnings for Youth
Little Cigars and Cigarillos (LCC) Use
N/A2024-07-18
RecruitingStudy of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells
Breast Cancer, Relapse, Resistant Cancer
Phase 12024-06-27
RecruitingDISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics
Hematologic Malignancies, Lymphoma, Multiple Myeloma
N/A2024-06-21
CompletedPharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya
Cervix Cancer, Cervix Intraepithelial Neoplasia Grade 3, Cervix; Intraepithelial Neoplasia, Grade I
Phase 12024-05-29
RecruitingBlood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Followi
Cervical Cancer
2024-05-03
RecruitingATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells
Hodgkin Lymphoma, Relapse, Refractory
Phase 1 / Phase 22024-04-25
RecruitingUNC Metastatic Cancer Radiation Therapy Registry
Cancer, Metastatic Cancer
2024-04-21
RecruitingAutologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
Head and Neck Cancer, Relapse, Recurrent
Phase 1 / Phase 22024-04-05
TerminatedAbequolixron (RGX-104) and Durvalumab in Lung Cancer
Non-Small Cell Lung Cancer
Phase 12024-04-01
CompletedArtesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya
Cervix Cancer, Cervix Neoplasm, Precancerous Conditions
Phase 12024-03-04
CompletedMobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors
Cancer, Physical Activity, Cancer Survivorship
N/A2024-03-01
Withdrawn18-fluorofuranylnorprogesterone (FFNP) PET/MRI as a Potential Biomarker of Response to Progesterone Therapy
Complex Atypical Hyperplasia, Endometrial Cancer
Phase 22024-02-15
CompletedImpact of E-Cigarette Prevention Messages on Adolescents
Vaping Behavior
N/A2024-02-05
RecruitingPromoting CT Engagement for Pancreatic Cancer With App
Pancreas Cancer
N/A2024-02-02
RecruitingThe Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study
Toxicity, Radiation Toxicity
Phase 1 / Phase 22023-12-15
Active Not RecruitingIsa-Pom-Dex in Elderly/Frail Subjects With RRMM
Multiple Myeloma, Relapse, Refractory
Phase 22023-12-05
RecruitingIntegrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast C
Breast Cancer, Breast Neoplasms
N/A2023-11-28
RecruitingImproving Thoracic Surgical Care Using Electronic Patient-Reported Outcomes (ePROS)
Thoracic
N/A2023-11-14
RecruitingGRID Therapy for Extremity Soft Tissue Sarcoma
Sarcoma
N/A2023-11-09
RecruitingThe Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer Treatment
Cancer, Breast Cancer, Colorectal Cancer
N/A2023-11-06
RecruitingONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer
Endometrial Cancer, Metastasis, Endometrioid Endometrial Cancer
Phase 12023-10-23
CompletedPhysical Activity and Healthy Eating Among Young Adult Cancer Survivors
Physical Activity, Neoplasms, Cancer
N/A2023-10-02
CompletedPhysical Therapy in Pre-cystectomy Patients
Bladder Cancer
2023-08-27
RecruitingBrain Slice Explants to Predict Drug Response in Brain Tumors
Central Nervous System Tumor
2023-07-27
RecruitingAutologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer
Lung Cancer, Small Cell Lung Carcinoma, Non Small Cell Lung Cancer
EARLY_Phase 12023-06-21
CompletedLittle Cigar and Cigarillo Warnings Among US Adults Who Use LCCs
Tobacco Use
N/A2023-05-22
CompletedenCompass Carolina: A Social Support and Coaching Program for Cancer Caregivers
Cancer
N/A2023-05-15
RecruitingUrine HPV Testing for Cervical Cancer Screening Among Women Living With HIV in South Africa
Cervical Cancer, CIN2, CIN3
N/A2023-05-11
Active Not RecruitingMeasuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
Cancer, Malignant Neoplasm
N/A2023-05-01
TerminatedIntervention to Address Psychosocial Needs Among Socially Disadvantaged Older Adults With Cancer
Hematological Disorder
N/A2023-04-28
Completed5-fluorouracil Following Cervical Intraepithelial Neoplasia Treatment Among HIV-positive Women in East Africa
CIN 2/3, HIV Infections
Phase 12023-04-26
Active Not RecruitingKaposi Sarcoma Chemotherapy and Research (KS-CARE)
Kaposi Sarcoma, HIV
2023-04-25
CompletedAcceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living
Cervical Cancer, CIN2, CIN3
N/A2023-03-22
RecruitingDisease Outcomes and Toxicities in Patients With Gastrointestinal and Sarcomatous Malignancies
Sarcoma, Gastrointestinal Cancer
2023-03-17
CompletedAssessing Functional Status Needs Via PRO Measures for Pts With Metastatic Breast Cancer
Breast Cancer, Metastasis
2023-03-17
CompletedRisk Stratification for Patients With Hospital-diagnosed Advanced Lung Cancer
Lung Cancer
2023-03-14
RecruitingComparison of CE-DBT and MRI in Patients With Known Breast Lesions
Breast Cancer
EARLY_Phase 12023-03-13
CompletedEngaging Clinical Champions to Improve HPV Vaccination
Human Papilloma Virus
N/A2023-03-08
Active Not RecruitingImpact of Financial Incentives
Human Papilloma Virus
N/A2023-02-28
CompletedImpact of E-cigarette Device Warnings
Vaping Behaviors
N/A2023-02-23
Active Not RecruitingImpact of Standing Orders Optimization
Human Papilloma Virus
N/A2023-02-22
RecruitingYoung Adult Infusion Space Experience Satisfaction Survey
Cancer
2023-02-20
TerminatedPolatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma
Diffuse Large B-cell Lymphoma
Phase 22023-02-17
RecruitingEvaluation of Child Care Staff Weight Management Program
Obesity
N/A2023-01-18
CompletedctDNA in Subjects With Muscle-invasive Bladder Cancer Treated With Trimodality Therapy
Bladder Cancer, Muscle-Invasive Bladder Carcinoma
2023-01-10
Active Not RecruitingLong-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary Treatment
Breast Cancer
2023-01-06
RecruitingAdaptation of a Values Assessment Tool
Cancer, Metastatic Breast Cancer
N/A2023-01-05
CompletedImpact of Physical and Occupational Therapy in New BMT Patients
Bone Marrow Transplantation, Bone Marrow Disease
2023-01-01
CompletedCD30 CAR for CD30+ NSGCT
Germ Cell Tumor, Nonseminomatous Germ Cell Tumor
Phase 22022-12-09
WithdrawnPSMA-PET/MRI Low- and Intermediate-Risk Prostate Cancer
Prostate Cancer
Phase 22022-11-29
CompletedPhysical Function During ARSI Treatment
Advanced Prostate Carcinoma
2022-10-13
RecruitingStudy of Trilaciclib and Lurbinectidin
Lung Cancer, Small-cell Lung Cancer
Phase 22022-10-12
CompletedMetastatic Breast Cancer-Specific Prognostic Tool
Metastatic Breast Cancer
2022-09-20
RecruitingAutologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc
Glioblastoma Multiforme
Phase 12022-09-02
Active Not RecruitingPembrolizumab Plus Olaparib in LA-HNSCC
Squamous Cell Carcinoma of Head and Neck
Phase 22022-09-02
CompletedFinding Barriers and Designing Solutions to Promote Women s Cancer Screening in South Africa
Cervical Cancer
2022-07-16
RecruitingEvaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Spec
Metastatic Breast Cancer, End of Life
2022-07-07
CompletedThe Families Addressing Cancer Together Intervention for Parents With Cancer
Neoplasms, Cancer, Parenting
N/A2022-07-05
Active Not RecruitingPatient Related Outcomes for Gynecologic Radiation Oncology
Gynecologic Cancer
2022-06-01
Terminated3-D Super Resolution Ultrasound Microvascular Imaging
Breast Cancer, Thyroid Cancer
Phase 22022-05-26
RecruitingCompare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
Breast Cancer, Quality of Life
Phase 22022-05-17
CompletedMobile Health App to Promote Participation of Black Women in Breast Cancer Clinical Trials
Breast Cancer
N/A2022-05-02
CompletedPre-Implementation Study of Improving Thoracic Surgical Care Using Electronic Patient-Reported Outcomes (ePROS
Thoracic Surgery
2022-04-07
CompletedUnderstanding What Matters Most to Patients: Establishing the Validity of a Best-Worst Scaling Survey
Hematologic Neoplasms
2022-03-21
CompletedConnecting Audio and Radio Sensing Systems to Improve Care at Home
Colorectal Cancer, Bladder Cancer, Ovarian Cancer
2022-03-21
Active Not RecruitingPRO-VISION: Patient Reported Outcomes-Based Monitoring of VEGF-Inhibitor Side Effects in ONcology
Renal Cell Carcinoma
N/A2022-03-18
RecruitingIsa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma
Multiple Myeloma, Cancer
Phase 22022-02-18
TerminatedPatient and Care Partner Experiences Living With Multiple Myeloma (PaCE-MM)
Multiple Myeloma
2022-02-08
CompletedFinancial Difficulty in Patients With Blood Cancer
Chronic Lymphocytic Leukemia, Multiple Myeloma
2022-01-27
RecruitingUNC Childhood, Adolescent, and Young Adult Cancer Cohort
Pediatric Cancer, Cancer, Cancer Metastatic
2021-12-17
CompletedGeriatric-assessment Interventions to Address Functional Deficits in Older Adults w Multiple Myeloma
Multiple Myeloma, Myeloma, Disability Physical
N/A2021-12-01
CompletedAddressing Cancer-Related Financial Toxicity in Rural Oncology Care Settings
Neoplasms, Carcinoma
N/A2021-11-11
CompletedRemote Monitoring of Lung Cancer Patient-Reported Outcomes Using Moovcare®
Lung Cancer, Neoplasms, Lung, Neoplasms, Pulmonary
N/A2021-09-01
WithdrawnNeoadjuvant Therapy for Localized Rectal Adenocarcinoma
Rectal Adenocarcinoma
Phase 22021-08-13
CompletedOvercoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study
Lynch Syndrome
N/A2021-08-01
CompletedImpact of Vaping Prevention Advertisements
Vaping
N/A2021-07-03
CompletedTransitioning Care: Perspectives of Older Women With Early Breast Cancer on Current Telemedicine Modalities
Breast Cancer Female, Breast Cancer
2021-07-02
CompletedCorrecting Public Misperceptions About Very Low Nicotine Content Cigarettes
Tobacco Use, Cigarette Use
N/A2021-07-01
Active Not RecruitingSafety and Efficacy of Rituximab for Treatment of Multicentric Castleman Disease in Malawi
Multicentric Castleman Disease
Phase 22021-06-22
CompletedMobile Coaching to Improve HPV Vaccine Delivery
HPV Vaccine, Provider Communication Practices, Vaccine Recommendation Practices
N/A2021-06-21
WithdrawnRelationship Between Circulating Tumor Cell Cultures' Treatment Response and Clinical Outcomes
Cancer, Metastasis Lung, Metastasis to Liver
2021-06-01
TerminatedDevelopment and Application of a Novel Digital Array PCR for Acute Myeloid Leukemia (AML)
Leukemia, Myeloid, Acute, Minimal Residual Disease
2021-05-28
Active Not RecruitingImmuno-Oncology Database and Bioregistry
Malignancy, Immune System Diseases, Autoimmune Diseases
2021-05-20
WithdrawnReverse Axillary Mapping in Breast Radiation Treatment Planning
Breast Cancer, Lymphedema
2021-05-01
CompletedTacrolimus in Allogeneic Hematopoietic Stem Cell Transplant (HCT)
Acute GVHD
2021-02-01
Active Not RecruitingPhase I Study of Autologous CAR T-Cells Targeting the B7-H3 Antigen in Recurrent Epithelial Ovarian
Epithelial Ovarian Cancer
Phase 12021-01-27
RecruitingProspective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associ
Oropharyngeal Squamous Cell Carcinoma, Carcinoma, Squamous Cell, Head and Neck Squamous Cell Carcinoma
2020-11-19
RecruitingStudy of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapse
Mantle Cell Lymphoma, Follicular Lymphoma, Splenic Marginal Zone Lymphoma
Phase 12020-11-12
CompletedChemotherapy-related Cognitive Impairment and Acute Leukemia
Acute Myeloid Leukemia
2020-11-03
CompletedFeasibility Testing of Patient Reported Outcomes - Informed Symptom Management System (PRISMS)
Colorectal Cancer, Bladder Cancer, Ovarian Cancer
N/A2020-11-02
Active Not RecruitingA Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas
Central Nervous System Lymphoma
Phase 22020-10-15
CompletedContrast-Enhanced Ultrasound for Kidney Cancer Subtyping and Staging
Kidney Cancer
Phase 22020-10-07
CompletedAn Evaluation of the Families Addressing Cancer Together (FACT) Intervention
Neoplasms, Cancer, Parenting
N/A2020-10-05
TerminatedPET/MR Characterization of Renal Cell Carcinomas
Renal Cell Carcinoma
N/A2020-10-01
Active Not RecruitingWindow of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer
Bladder Cancer
Phase 22020-09-23
CompletedRN-Led Palliative and Supportive Care Intervention
Acute Myeloid Leukemia
N/A2020-09-14
CompletedClinical Evaluation of Primary Sampling Scatter Correction for Chest Tomosynthesis
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
N/A2020-08-26
CompletedOlanzapine for Nausea/Vomiting Prophylaxis in Recipients of Hematopoietic Stem Cell Transplants
Chemotherapy-induced Nausea and Vomiting
Phase 32020-08-18
TerminatedPSMA-PET/MRI Unfavorable-Risk Target Volume Pilot Study
Prostate Cancer
Phase 22020-07-16
CompletedEffect of Incidental Findings Information on Lung Cancer Screening Intent
Neoplasm of Lung, Decision Support Techniques, Mass Screening
N/A2020-07-16
CompletedScaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)
Colorectal Cancer
N/A2020-07-07
CompletedHPV-Based Screen-and-Treat Demonstration Project in Lilongwe
HPV Infection, Cervical Cancer, HIV Infections
N/A2020-06-24
CompletedPatient-centered Communication About Healthy Weight in Early Breast Cancer
Breast Cancer
2020-06-15
WithdrawnParsaclisib in Newly Diagnosed Stage I-IIIC Triple Negative or HER2+ Breast Cancer
Breast Cancer, Breast Neoplasms, Triple Negative Breast Cancer
Phase 12020-06-01
CompletedThe HealthScore Health Coaching Program
Cancer, Survivorship, Quality of Life
N/A2020-05-11
CompletedImproving Quality of Life After Thoracic Surgery Using Patient-Reported Outcomes
Thoracic Surgery
N/A2020-04-30
CompletedLCCC1931:Post-treatment Intervention in Women With Breast Cancer (70y/o+)
Breast Cancer
2020-03-12
CompletedApplication of Plasma Circulating HPV DNA Testing to Management of Cervical Intraepithelial Neoplasia
Cervix Lesion, Cervical Cancer
2020-02-26
TerminatedEarly Intervention for Impairments Identified During Comprehensive Geriatric Assessment in Patients With Bladd
Bladder Cancer
N/A2020-01-21
RecruitingCirculating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma
Head and Neck Neoplasm, Carcinoma, Squamous Cell
2020-01-14
RecruitingMRI Biomarkers for Radiation-Induced Neurocognitive Decline Following SRS of Newly Diagnosed Brain Mets
Brain Metastases, Neurocognitive Deficit, White Matter Alterations
2019-12-04
TerminatedFathers and Mothers Invested in Lives of Their Youth (FAMILY) Study: A Pilot Intervention
Metastatic Breast Cancer, Parenting
N/A2019-10-30
Active Not RecruitingDurvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN
Larynx, Lip, Oral Cancer
Phase 22019-10-07
CompletedMemantine for Prevention of Cognitive Decline in Patients With Breast Cancer
Cognitive Decline, Chemo-brain
Phase 22019-09-25
CompletedHigh Intensity Interval Training in Endometrial Cancer
Endometrial Cancer
N/A2019-09-23
CompletedContrast-enhanced Ultrasound as a Screening Tool for Kidney Cancer in Patients With Von-Hippel Lindau
Von-Hippel Lindau, Kidney Disease, Chronic
Phase 22019-09-23
RecruitingCD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma
Peripheral T Cell Lymphoma
Phase 22019-09-17
Active Not RecruitingStudy of PD-1 Inhibitors After CD30.CAR T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma
Relapsed Hodgkin Lymphoma, Refractory Hodgkin Lymphoma
EARLY_Phase 12019-09-01
CompletedPrecision Dosing of Tyrosine Kinase Inhibitors in CML Patients
CML, Chronic Phase, CML (Chronic Myelogenous Leukemia, CML - Philadelphia Chromosome
2019-06-20
RecruitingTumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma (PDAC), Cancer of Pancreas, Pancreatic Cancer, Adult
Phase 22019-06-12
CompletedThe STEPP Study: Sensors To Evaluate Physical Performance
Oncology
N/A2019-04-24
TerminatedWindow of Opportunity Pilot Study of Pembrolizumab in Obesity-driven Endometrial Cancer
Endometrial Cancer, Uterine Cancer
EARLY_Phase 12019-03-29
CompletedAcademic-Industrial Partnership for Translation of Acoustic Angiography
Signs and Symptoms
Phase 42019-03-25
CompletedTesting the Utilization of a Mobile Health App for Patients Undergoing Cystectomy Surgery for Bladder Cancer
Invasive Bladder Cancer
N/A2019-03-25
CompletedAn Exploratory Study of Pembrolizumab Plus Entinostat in Non-Inflamed Stage III/IV Melanoma
Melanoma
Phase 22019-03-22
Active Not RecruitingAnti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma
Lymphoma, Lymphoma, B-Cell, Immune System Diseases
Phase 12019-03-12
TerminatedA Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion
Malignant Pleural Effusion, Stage IV Metastatic Cancer, Lung Cancer
Phase 1 / Phase 22019-03-06
RecruitingStudy of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/
Neuroblastoma, Osteosarcoma
Phase 12019-02-19
CompletedNovel MRI Sequence MR Fingerprinting in Breast MRI Feasibility Study
Breast Screening
N/A2019-02-18
Active Not RecruitingStudy of ATLCAR.CD138 Cells for Relapsed/Refractory Multiple Myeloma
Multiple Myeloma, Immune System Diseases
Phase 12019-01-14
Active Not RecruitingStudy of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL
Lymphoma, Immune System Diseases, Immunoproliferative Disorders
Phase 12018-12-12
TerminatedPET/MR in Surgical Planning for Breast CA Treated With Neoadj Chemo
Breast Cancer
N/A2018-12-05
TerminatedWindow of Opportunity Trial of Entinostat in Patients With Newly Diagnosed Stage I-IIIC,TNBC
Breast Cancer, Invasive Breast Cancer, ER-Negative PR-Negative HER2-Negative Breast Cancer
EARLY_Phase 12018-11-28
RecruitingHarnessing Analysis RNA Expression and Molecular Subtype to Optimize Novel TherapY MBCA
Breast Cancer
N/A2018-11-06
CompletedGRADE-SRM: Genomic Risk Assessment and Decisional Evaluation for Small Renal Masses
Small Renal Mass, Kidney Tumor
N/A2018-10-30
Active Not RecruitingBV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma
Lymphoma, Adult T-Cell Leukemia/Lymphoma, Lymphatic Diseases
Phase 22018-10-11
CompletedMultimedia Aid Gynecologic Counseling and Consent
Endometrium Cancer, Sentinel Lymph Node, Perioperative/Postoperative Complications
N/A2018-10-01
CompletedMOtiVating Endometrial Cancer Survivors With Activity Monitors and Tailored Feedback
Endometrial Cancer
N/A2018-09-28
CompletedDenosumab + PD-1 in Subjects With Stage III/ IV Melanoma
Melanoma Stage Iii, Melanoma Stage Iv, Melanoma
Phase 22018-09-10
CompletedPromoting Physical Activity in Young Adult Cancer Survivors Using mHealth and Adaptive Tailored Feedback Strat
Physical Activity, Neoplasms, Neoplasms by Site
N/A2018-08-23
CompletedEfficacy of a Couple-Focused mHealth Symptom Self-management Program
Prostate Cancer
N/A2018-05-30
CompletedARFI, VisR and DDAI Ultrasound for Improving Discrimination of Malignant and Unresponsive Breast Cancer
Breast Cancer
2018-05-10
CompletedTrial of Parotid Sparing Whole Brain Radiation
Xerostomia
N/A2018-05-09
CompletedPET/MR in Assessing Response to Neoadjuvant Radiation Therapy in the Tx of High Grade Sarcomas
Sarcoma
N/A2018-04-01
CompletedPalbociclib and Cetuximab in Metastatic Colorectal Cancer
Cancer of the Colon, Colon Cancer, Colon Neoplasms
Phase 22018-03-23
CompletedPhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC
Colon Cancer
Phase 22018-03-09
CompletedFunctional Sparing of Salivary Glands Using MRI Sialography for Patients Undergoing Definitive Radiation Thera
Head and Neck Cancer, Oropharynx Cancer, Xerostomia Due to Radiotherapy
N/A2018-03-08
CompletedPilot Evaluation of a Microfluidic Assay to Detect Minimal Residual Disease and Predict Relapse in AML Patient
Acute Myeloid Leukemia
2018-03-01
CompletedImpact of Home-based Aerobic and Strength Exercises During Chemotherapy for Early Breast Cancer on Biomarkers
Breast Cancer
N/A2018-02-28
CompletedmHealth Physical Activity Intervention for Survivors of Adolescent and Young Adult Cancers
Cancer, Physical Activity
N/A2018-02-28
CompletedAssessing the Feasibility of Screening and Treating Anxiety and Depression in the Bone Marrow Transplant Popul
Anxiety, Depression
2018-02-22
RecruitingRegistry for Adults With Plasma Cell Disorders (PCD's)
Multiple Myeloma, Amyloidosis, Cryoglobulinemia
2018-02-09
RecruitingUlixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors
Tumor, Solid, Pancreatic Cancer, Melanoma
Phase 12018-01-30
RecruitingUNC Pleural Fluid Registry
Lung Cancer, Lung Infection, Breast Cancer
2018-01-24
Active Not RecruitingCarboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Car
Carcinoma, Squamous Cell, Oral Cancer, Oropharynx Cancer
Phase 22017-12-19
CompletedFeasibility of an 8-week Tai Chi Chuan Intervention for Breast Cancer Survivors
Cancer, Breast, Cognitive Impairment
N/A2017-12-05
CompletedHigh Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplant
Hematopoietic Stem Cell Transplantation, Delirium, Thiamine Deficiency
Phase 22017-10-16
CompletedEnhancing Source Credibility in Tobacco Regulatory Communications
Cigarette Smoking Behavior
N/A2017-10-10
CompletedEnhancing Survivorship Care Planning for Patients With Localized Prostate Cancer Using A Couple-focused Web-ba
Prostate Cancer
N/A2017-08-03
CompletedA Culturally-adapted Colorectal Cancer Screening Decision Aid Designed for American Indians
Colorectal Cancer
N/A2017-08-01
CompletedHIV and Other Risk Factors for Esophageal Squamous Cell Carcinoma in Malawi
Esophageal Squamous Cell Carcinoma
2017-07-26
CompletedA Patient Portal Tool, E-assist, for Supporting CRC Screening
Colorectal Cancer
N/A2017-06-14
CompletedUsing PROMIS as Part of Routine Clinical Care for Racially Diverse Prostate and Bladder Cancer Patients
Prostate Cancer, Bladder Cancer
2017-05-08
CompletedPembrolizumab TX-naive Distant Mets Melanoma and Use of (C11-AMT) PET at Baseline as Imaging Biomarker
Melanoma
Phase 22017-04-19
CompletedSelective Image Guided Resection of Pathologically Documented Axillary Lymph Node Metastases
Breast Cancer
N/A2017-04-07
CompletedHome-based Exercise Intervention for Patients With Metastatic Prostate Cancer
Castration-resistant Prostate Cancer, Androgen Deprivation Therapy
N/A2017-04-01
CompletedGet REAL and HEEL Research Program
Breast Cancer
2017-03-20
WithdrawnPlasma Circulating Tumor DNA Analyses in ER+ Metastatic Breast Cancer
Metastatic Breast Cancer
2017-01-13
Terminated18-FLT PET/MR Imaging to Predict Graft Failure and GVHD in Bone Marrow Transplant Patients
Graft Vs Host Disease
EARLY_Phase 12017-01-01
CompletedP53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCC
Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms
Phase 22016-12-01
CompletedCancer Patients' Performance Status Assessed Using Cardiopulmonary Exercise Testing and Wearable Data Generati
Malignant Solid Tumor, Hematologic Malignancies
2016-11-01
CompletedStudy Of Single-dose Cyclophosphamide +Pembrolizumab In Patients With Metastatic Triple Negative Breast Cancer
Triple Negative Breast Cancer
Phase 22016-10-18
CompletedMailed Reminders Plus Fecal Immunochemical Testing
Colorectal Cancer Screening, Colorectal Cancer
N/A2016-10-01
TerminatedA Phase I Study of Alisertib + R-EPOCH for Treatment of Myc-Positive Aggressive B-cell Lymphomas
Diffuse Large B-cell Lymphoma, Follicular Lymphoma, Burkitt Lymphoma
Phase 12016-10-01
CompletedPhase II Trial of Sequential Consolidation With Pembrolizumab Followed by Nab-paclitaxel
Non Small Cell Lung Cancer
Phase 22016-09-13
CompletedInvestigating Chemotherapy Treatments, Response and Subsets of HIV-associated Kaposi Sarcoma in Malawi
Kaposi Sarcoma, HIV
2016-09-01
Active Not RecruitingStudy of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL
Lymphoma, Lymphoma, Non-Hodgkin, Immune System Diseases
Phase 1 / Phase 22016-08-26
CompletedHigh Dose Cytarabine Followed by Pembrolizumab in Relapsed/Refractory AML
Acute Myeloid Leukemia, in Relapse
Phase 22016-08-22
Active Not RecruitingAdministration of T Lymphocytes for Prevention of Relapse of Lymphomas
Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin
Phase 12016-06-07
CompletedPembrolizumab + Radiation for Locally Adv SCC of the Head and Neck (SCCHN) Not Eligible Cisplatin
Head and Neck Cancer
Phase 22016-05-16
CompletedPhase 2 Study of Pembrolizumab in Combination With Gemcitabine and Cisplatin as Neoadjuvant Therapy
Bladder Cancer
Phase 22016-05-01
CompletedGeriatric Assessment Reporting in Real Time (GARRT) in Non-electively Hospitalized Older Cancer Patients
Oncology
N/A2016-04-25
CompletedEffect of Human Papillomavirus Self-Collection on Cervical Cancer Screening in High Risk Women: My Body, My Te
Cervical Cancer, Uterine Cervical Neoplasms, Human Papillomavirus
N/A2016-04-01
CompletedCulture of Circulating Tumor Cells Isolated From Cancer Patients With Metastatic Disease
Circulating Tumor Cells
2016-04-01
CompletedRituximab Plus CHOP Chemotherapy for Diffuse Large B-cell Lymphoma
Diffuse Large B-cell Lymphoma, HIV
Phase 22016-03-01
CompletedAssessing Physical Fitness in Cancer Patients With Cardiopulmonary Exercise Testing and Wearable Data Generati
Malignant Solid Tumour, Hematologic Malignancies, Planned Hematopoietic Cell Transplantation
2016-02-01
TerminatedTrial of Pregabalin for Granulocyte Colony-stimulating Factor (GCSF)-Induced Bone Pain
Breast Cancer, Lymphoma, Pain
Phase 22016-01-27
CompletedA Pre-Op Window Study Evaluating Anti-Proliferative Effects of Atorvastatin on the Endometrium
Endometrial Cancer
EARLY_Phase 12015-11-01
CompletedDose-escalating AZD1775 + Concurrent Radiation + Cisplatin for Intermediate/High Risk HNSCC
Carcinoma, Squamous Cell of Head and Neck
Phase 12015-10-26
CompletedPhysical Activity to Maintain Quality of Life and Physical Function in Women With Metastatic Breast Cancer: a
Metastatic Breast Cancer
N/A2015-10-01
CompletedProspective Evaluation of Patient Reported Xerostomia After Whole Brain Radiation
Xerostomia
2015-10-01
CompletedFitness in Allogeneic Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation
N/A2015-09-01
CompletedPre-Post Study for Supporting Appropriate Implementation of Lung Cancer Screening
Lung Neoplasms, Early Detection of Cancer, Decision Support Techniques
N/A2015-05-01
TerminatedPhase II Trial of Palbociclib in Patients With Metastatic Urothelial Cancer After Failure of First-Line Chemot
Metastatic Urothelial Carcinoma (UC)
Phase 22015-03-17
TerminatedCisplatin and Nab-paclitaxel for (N2) Defined NSCLC
Stage IIIA Non-Small Cell Lung Cancer
Phase 22015-01-01
CompletedImpact of Physical Activity on Biomarker of Aging and Body Composition Among Breast Cancer Survivors Age 65 an
Breast Cancer, Aging, Physical Activity
N/A2014-10-01
CompletedDe-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study
Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms
Phase 22014-08-01
CompletedThe Ability of Electronic Patient Symptom Reporting to Reduce Symptom Burden During Hospitalization for Chemot
Stem Cell Transplantation, Hematopoietic
N/A2014-07-01
CompletedWeekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHN
Head and Neck Cancer, Squamous Cell Carcinoma of the Head and Neck
Phase 22014-06-16
CompletedThe CARE Program: CAncer REhabilitation Pilot Study for Older Adults
Cancer
N/A2014-06-01
CompletedThe Effect of Walking on Fatigue After Chemotherapy in Patients 65 and Older
Cancer, Geriatric, Fatigue
N/A2014-06-01
CompletedComparison of the Sensitivity and Specificity of Acoustic Angiography to the Sensitivity and Specificity of Co
Signs and Symptoms
N/A2014-06-01
CompletedPhysical Activity Intervention for Older Patients During Chemotherapy for Colorectal Cancer
Colorectal Cancer, Fatigue
N/A2014-06-01
WithdrawnFLT PET/MR for Evaluation of Pseudoprogression in Patients With Brain Lesions
Brain Lesions, Brain Metastasis, Brain Metastases
2014-05-07
CompletedGenotype-Directed Study Of Irinotecan Dosing In FOLFIRI + BevacizumabTreated Metastatic Colorectal Cancer
Colon Cancer
Phase 22014-05-06
CompletedInvestigation of Circulating Tumor Cells From Cancer Patients Undergoing Radiation Therapy
Circulating Tumor Cells
2014-05-01
WithdrawnExercise Intervention for Pts With Metastatic Castration-Resistant Prostate Cancer Receiving Abiraterone or En
Metastatic Castration Resistant Prostate Cancer (mCRPC)
N/A2014-04-01
CompletedThe Impact of a Physical Activity Program on Biomarkers of Aging During Chemotherapy for Breast Cancer
Breast Cancer, Aging
2014-03-01
CompletedMetformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperpla
Complex Atypical Hyperplasia, Endometrial Cancer
Phase 22014-02-27
CompletedEvaluation of the Lung Nodule Sensitivity of Stationary Chest Tomosynthesis in Patients With Known Lung Nodule
Signs and Symptoms
N/A2014-02-01
CompletedObservational Longitudinal Study of Pain in Men With Metastatic Castrate-Resistant Prostate Cancer
Metastatic Castrate-Resistant Prostate Cancer
2014-01-23
CompletedThe Use of Smart Scales for Weight Gain Prevention in African American Breast Cancer Survivors
Body Weight Changes, Breast Neoplasms
N/A2014-01-01
CompletedExercise and Quality of Life in Leukemia Patients
Acute Leukemia
N/A2014-01-01
TerminatedNeoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer
Rectal Cancer
Phase 1 / Phase 22013-12-01
TerminatedMonitoring of Oral Human Papillomavirus Infection (HPV) in HPV-positive Oropharyngeal Squamous Cell Carcinoma
Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms
N/A2013-12-01
CompletedImproving Survivorship Care Through Enhanced Communication and Coordination: Pilot Study
Cancer
N/A2013-12-01
TerminatedUsing Walk With Ease Walking Program With Men 65 and Older Being Treated for Prostate Cancer
Prostate Cancer
2013-10-01
CompletedRadiation Adherence/Toxicity in Patients With Non-Ovarian Gynecological Cancers
Non-ovarian Gynecological Cancers
2013-09-01
TerminatedPilot Study: Utilizing Manometry to Assess Radiation-Induced Changes in Esophageal Function
Lung Cancer
2013-09-01
CompletedDefining the HER2 Positive (+) Breast Cancer Kinome Response to Trastuzumab, Pertuzumab, Combination Trastuzum
Breast Neoplasms
EARLY_Phase 12013-08-05
No Longer AvailableSingle Subject Neratinib in Bladder Cancer (NRR)
Bladder Cancer
2013-07-01
CompletedSingle Arm on the Tolerability of Weekly Nab-paclitaxel
Non Small Cell Lung Cancer (NSCLC)
Phase 22013-06-25
CompletedEvaluation of Cardiorespiratory Performance After Interval Exercise Training Prior to Hematopoietic Cell Trans
Stem Cell Transplantation, Hematopoietic
N/A2013-06-01
CompletedEffect of Curcumin on Dose Limiting Toxicity and Pharmacokinetics of Irinotecan in Patients With Solid Tumors
Advanced Colorectal Cancer
Phase 12013-06-01
CompletedOpen-label Pilot Evaluating Renal Lesions w/ Contrast-enhaced US in Patients w/ Renal Cancer
Kidney Cancer
EARLY_Phase 12013-05-01
CompletedLCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in
Stage III Melanoma, Stage IV Melanoma, Unresectable Melanoma
Phase 22013-04-04
CompletedAssessment of Ability of Breath Hold for Left-sided Breast Cancer Radiation Therapy to Reduce Side Effects to
Breast Cancer
2013-03-01
CompletedPET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1)
Neurofibromatosis-1, Optic Glioma, Plexiform Neurofibroma
2013-01-16
CompletedMetformin for the Treatment of Endometrial Hyperplasia
Endometrial Hyperplasia, Endometrial Hyperplasia Without Atypia
EARLY_Phase 12013-01-10
CompletedComparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Known Breast Lesion
Breast Neoplasms
2013-01-01
CompletedStereotactic Radiosurgery or Other Local Ablation Then Erlotinib in Epidermal Growth Factor Receptor (EGFR)
Non Small Cell Lung Cancer
Phase 22012-12-11
RecruitingClinical Cohort of Lymphoma Patients in Malawi
Lymphoma, Hematologic Malignancies
2012-11-01
CompletedPredicting Tolerance to Radiation Therapy in Older Adults With Cancer
Pre-treatment Loss of Independent Activities of Daily Living
2012-11-01
CompletedPET/MRI as a Predictor of Response to Pre-op Chemoradiation in Resectable Rectal Cancer: a Pilot Study
Rectal Carcinoma
2012-10-01
CompletedFeasibility of an Evidence-based Walking Program in Cancer Pts 60+ During Chemotherapy
Breast Cancer, Colon Cancer, Lung Cancer
2012-10-01
CompletedHybrid PET/MR in the Therapy of Cervical Cancer
Cervix Carcinoma, Cervical Squamous Cell Carcinoma, Cervical Adenosquamous Carcinoma
2012-10-01
CompletedImaging Correlates of Renal Cell Carcinoma Biological Features
Renal Cell Carcinoma
N/A2012-08-01
CompletedPositron Emission Tomography (PET) Study for Staging of Muscle Invasive Bladder Cancer
Bladder Cancer
N/A2012-07-24
CompletedStudy of Outcomes After Surgery/Treatment to Treat Bladder Cancer
Bladder Cancer
2012-07-23
CompletedFinding Predictors of Side Effects to Chemoradiation Treatment in Elderly Patients With Head and Neck Cancer
Head and Neck Cancer
2012-07-01
CompletedLenalidomide as Consolidation and Maintenance in Adults >/= 60 Years of Age With AML Following Standard Induct
Acute Myeloid Leukemia
Phase 12012-06-28
CompletedPatient Preferences for Breast Reconstruction After Mastectomy
Breast Cancer
2012-06-01
CompletedMultimodality Risk Adapted Tx Including Induction Chemo for SCCHN Amenable to Transoral Surgery
Head and Neck Cancer, Squamous Cell Carcinoma of the Head and Neck
Phase 22012-06-01
CompletedCardiovascular Risk and Preventive Care in Prostate Cancer Patients Receiving Radiation and Hormone Therapy
Prostate Cancer
2012-06-01
CompletedBKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancer
Advanced Solid Tumors, Metastatic Colorectal Cancer, Metastatic Pancreatic Cancer
Phase 12012-05-01
WithdrawnStudy of Vorinostat With Doxil and Bortezomib for Patients With Relapsed/Refractory Multiple Myeloma
Multiple Myeloma
Phase 22012-04-01
WithdrawnCrossover Evaluation of Effect of Atorvastatin on PK of Irinotecan in CRC Patients Receiving FOLFIRI
Advanced Adenocarcinoma of the Colon or Rectum
Phase 12012-04-01
CompletedInduction Chemo w/ABVD Followed by Brentuximab Vedotin Consolidation in Newly Diagnosed, Non-Bulky Stage I/II
Hodgkin Lymphoma, Adult
N/A2012-04-01
Active Not RecruitingAdministration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refract
Acute Lymphoblastic Leukemia, Immune System Diseases, Immunoproliferative Disorders
Phase 1 / Phase 22012-03-22
CompletedDe-intensification of Radiation & Chemotherapy in Low-Risk Human Papillomavirus-related Oropharyngeal Squamous
Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms
Phase 22012-02-07
CompletedInduction Chemotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Head and Neck Cancer
Phase 22012-02-01
CompletedDefining the Triple Negative Breast Cancer Kinome Response to GSK1120212
Breast Cancer
EARLY_Phase 12012-01-01
TerminatedFOLFIRINOX for Unresectable Locally Advanced and Borderline Resectable Pancreatic Cancer
Pancreatic Cancer
Phase 22012-01-01
CompletedCirculating Tumor Cells in Solid Tumors
Solid Tumor, Adult
2011-12-09
WithdrawnSelective IMRT for Locally Advanced Head and Neck Carcinoma With Concurrent Panitumumab
Head and Neck Cancer
Phase 22011-12-01
CompletedEverolimus and Pasireotide (SOM230) in Patients With Advanced or Metastatic Hepatocellular Carcinoma
Advanced Adult Hepatocellular Carcinoma
Phase 22011-12-01
WithdrawnAdministration of T Lymphocytes for Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma (CART CD30)
Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma
Phase 12011-10-03
CompletedDevelopment of a Tumor Molecular Analyses Program and Its Use to Support Treatment Decisions
Neoplasm
N/A2011-09-01
CompletedA Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain Metastases
HER-2 Positive Breast Cancer
Phase 22011-09-01
CompletedStudy of BKM120 or BYL719 and Capecitabine in Patients With Metastatic Breast Cancer
Metastatic Breast Cancer
Phase 12011-08-01
CompletedNeoadjuvant Pazopanib in Renal Cell Carcinoma
Renal Cell Carcinoma
Phase 22011-06-01
WithdrawnOfatumumab In Older Patients With Untreated Low Or Intermediate Risk Indolent B-Cell Lymphomas
Lymphoma, Non-Hodgkin, Lymphoma, Follicular, Lymphoma, B-Cell, Marginal Zone
Phase 22011-06-01
CompletedPreoperative Window Study of Metformin for the Treatment of Endometrial Cancer
Endometrial Cancer
EARLY_Phase 12011-05-01
CompletedBavituximab Plus Carbo and Pemetrexed in Chemo-Naive Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Non Small Cell Lung Cancer (NSCLC)
Phase 12011-05-01
CompletedRegorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer
Colorectal Cancer Metastatic
Phase 22011-04-07
CompletedBendamustine + Rituximab in Older Patients With Previously Untreated Diffuse Large B-cell Lymphoma
Diffuse Large B-Cell Lymphoma, Lymphoma, Diffuse Large-Cell, Diffuse Large-Cell Lymphoma
Phase 22011-03-01
CompletedRetinal Oxygen Function After Radiation Therapy
A History of Radiation Therapy for a Tumor in the Vicinity of the Retina(s)
2011-03-01
CompletedReduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
Phase 22011-01-07
CompletedPilot Study to Evaluate Individualized Choice of Antidepressants in Patients With Cancer
Major Depressive Disorder, Neoplasms
EARLY_Phase 12011-01-01
CompletedNorth Carolina Prostate Cancer Comparative Effectiveness & Survivorship Study (NC ProCESS)
Cancer of Prostate, Cancer of the Prostate, Prostate Cancer
2011-01-01
CompletedStudy of the P16 Gene as a Predictor of Myelosuppression in Breast Cancer Patients
Breast Cancer
2010-12-01
CompletedPazopanib In Stage IIIB/IV NSCLC Lung Cancer After Progression on First Line Therapy Containing Bevacizumab
Lung Cancer
Phase 22010-12-01
CompletedPK Study of Oral and IV Clofarabine in High Risk Myelodysplasia+Acute Leukemias
Myelodysplastic Syndrome, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia
Phase 12010-09-01
TerminatedUse of Palliative Performance and Symptom Distress Scales in Older Patients With Advanced Ovarian Cancer
Ovarian Cancer
2010-06-01
TerminatedTrisenox® in Women With Metastatic Endometrial Cancer
Endometrial Carcinoma
Phase 22010-03-01
CompletedCarboplatin, Pemetrexed Disodium, and Bevacizumab for Patients With Stage III or IV Non-Small Cell Lung Cancer
Lung Cancer
Phase 22010-03-01
CompletedBiomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy
Colorectal Cancer, Diarrhea, Neutropenia
Phase 12010-02-01
CompletedBiomarkers in Blood Samples From Older Breast Cancer Survivors
Breast Cancer
2010-01-01
TerminatedTemsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft T
Brain and Central Nervous System Tumors, Neuroblastoma, Sarcoma
Phase 12009-11-01
RecruitingRegistry of Older Patients With Cancer
Chronic Myeloproliferative Disorders, Cognitive/Functional Effects, Leukemia
2009-09-01
CompletedSorafenib Tosylate and Chemoembolization With Doxorubicin Hydrochloride and Mitomycin in Treating Patients Wit
Liver Cancer
Phase 12009-07-22
RecruitingTissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
2009-07-01
WithdrawnCarboplatin, Ixabepilone, and Cetuximab in Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Prev
Lung Cancer
Phase 22009-07-01
CompletedSafety, Efficacy, and Dosing of Stereotactic Radiosurgery for Hepato-cellular Carc/Colo-rectal Liver Metastase
Liver Neoplasms, Colonic Neoplasms, Metastatic Cancer to Liver
N/A2009-04-01
CompletedBiomarkers Related to Thrombosis in Patients With Newly Diagnosed Multiple Myeloma Receiving Chemotherapy
Multiple Myeloma, Plasma Cell Neoplasm, Thromboembolism
2008-12-01
TerminatedVorinostat, Bortezomib, and Doxorubicin Hydrochloride Liposome in Treating Patients With Relapsed or Refractor
Multiple Myeloma and Plasma Cell Neoplasm
Phase 12008-10-01
TerminatedSorafenib in Treating Patients With Locally Advanced or Metastatic Liver Cancer and Cirrhosis
Liver Cancer
Phase 12008-10-01
CompletedDigital Breast Tomosynthesis Preference Study
Breast Cancer
2008-10-01
CompletedStudying Blood Samples From Women With Breast Cancer or Ductal Carcinoma In Situ Who Are Receiving Tamoxifen
Breast Cancer, Menopausal Symptoms
Phase 22008-06-18
TerminatedRadiation Induced Cardiopulmonary Injury in Humans
Thoracic, Pulmonary Injury, Heart Injuries
2008-06-01
CompletedEverolimus, Fluorouracil, Leucovorin, Panitumumab, and Oxaliplatin in Treating Patients With Tumors That Did N
Unspecified Adult Solid Tumor, Protocol Specific
Phase 12008-03-01
TerminatedClofarabine and Gemtuzumab in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Leukemia
Phase 12007-11-01
CompletedSorafenib Combined With Cisplatin and Etoposide or Carboplatin and Pemetrexed in Treating Patients With Metast
Unspecified Adult Solid Tumor, Protocol Specific
Phase 12007-09-01
TerminatedPh II of Vinflunine and Cetuximab in Second Line Treatment of NSCLC
Lung Cancer
Phase 22007-08-01
CompletedVisibility of Lesion Characteristics With Phase Contrast Mammography
Breast Cancer
N/A2007-04-01
TerminatedEfalizumab in Treating Patients With Graft-Versus-Host Disease of the Skin That Did Not Respond to Previous St
Graft Versus Host Disease
N/A2006-12-01
CompletedSorafenib in Treating Patients Undergoing Surgery for Stage II, Stage III, or Stage IV Kidney Cancer
Kidney Cancer
EARLY_Phase 12006-11-01
CompletedOxaliplatin, Capecitabine, and Cetuximab in Treating Patients With Advanced Liver Cancer
Liver Cancer
Phase 22006-10-01
CompletedVinflunine and Erlotinib or Pemetrexed in Treating Patients With Unresectable or Metastatic Solid Tumors
Unspecified Adult Solid Tumor, Protocol Specific
Phase 12006-08-01
CompletedPaclitaxel Albumin-Stabilized Nanoparticle Formulation and Gemcitabine in Treating Patients With Advanced Meta
Unspecified Adult Solid Tumor, Protocol Specific
Phase 12006-08-01
CompletedBortezomib, Rituximab, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Relapsed or Refractory
Lymphoma
Phase 12006-07-01
CompletedErlotinib Before and After Surgery in Treating Patients With Muscle-Invasive Bladder Cancer
Bladder Cancer
Phase 22006-05-01
CompletedLapatinib and Radiation Therapy in Treating Patients With Locally Recurrent or Chemotherapy-Refractory Locally
Breast Cancer
Phase 12006-04-01
TerminatedStudy of Abraxane and Carboplatin to Treat Small Cell Lung Cancer
Small Cell Lung Cancer
Phase 22006-04-01
CompletedPh II Gemcitabine, Erlotinib, and Gemcitabine With Erlotinib/Elderly Patients W/ IIIB/IV NSCLC
Lung Cancer
Phase 22006-03-01
CompletedLow Antioxidant Diet in Controlling Cachexia in Patients With Oropharyngeal Cancer Receiving Chemotherapy and
Cachexia, Head and Neck Cancer, Weight Changes
Phase 12006-02-01
CompletedIndividualized Exercise Programs for Patients Receiving Chemotherapy for Newly Diagnosed Acute or Relapsed Mye
Depression, Fatigue, Leukemia
N/A2006-02-01
CompletedCombination Chemotherapy, Bev, RT, and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cance
Lung Cancer
Phase 1 / Phase 22006-01-01
CompletedVaccine Therapy, Trastuzumab, and Vinorelbine in Treating Patients With Locally Recurrent or Metastatic Breast
Breast Cancer
Phase 22005-12-01
CompletedCetuximab + / - Carboplatin for Estrogen Receptor-Negative, Progesterone Receptor-Negative Metastatic Breast C
Breast Cancer
Phase 22005-11-01
CompletedLapatinib in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy
Prostate Cancer
Phase 22005-10-01
CompletedAllogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
Phase 1 / Phase 22005-10-01
TerminatedErlotinib in Treating Patients With Progressive Glioblastoma Multiforme
Brain and Central Nervous System Tumors
Phase 12005-09-01
CompletedEffect of Aprepitant on Cyclophosphamide Pharmacokinetics in Patients With Breast Cancer
Breast Cancer, Nausea and Vomiting
Phase 12005-08-01
CompletedDocetaxel, Androgen Ablation, and External-Beam Radiation Therapy in Patients With High-Risk Localized Prostat
Prostate Cancer
Phase 1 / Phase 22005-08-01
CompletedFludeoxyglucose F 18-PET Imaging for Early Detection of Residual Disease in Patients Undergoing Radiofrequency
Colorectal Cancer, Metastatic Cancer
N/A2005-07-01
CompletedOctreotide in Treating Patients With Locally Advanced or Metastatic Liver Cancer
Liver Cancer
Phase 22005-07-01
TerminatedWhole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lu
Lung Cancer, Metastatic Cancer
Phase 22005-05-01
WithdrawnUsing Magnetic Resonance Spectroscopy With MRI to Non-invasively Determine Breast Cancer Extent of Disease
Breast Cancer
N/A2005-03-01
CompletedIrinotecan, Cisplatin, and Radiation Therapy With or Without Celecoxib in Treating Patients With Stage II, Sta
Esophageal Cancer
Phase 22005-03-01
CompletedCarboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or M
Unspecified Adult Solid Tumor, Protocol Specific
Phase 12004-12-01
CompletedMammography Reminders for Encouraging Women to Undergo Regular Mammography Screenings for Breast Cancer
Breast Cancer
2004-09-01
CompletedOxaliplatin, Gemcitabine, Erlotinib, and Radiation Therapy in Treating Patients With Unresectable and/or Metas
Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Pancreatic Cancer
Phase 12004-08-01
CompletedPh II Adjuvant Carboplatin/Docetaxel in Curatively Resected Stage I-IIIA NSCLC
Lung Cancer
Phase 22004-05-01
CompletedGenistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal Women
Breast Cancer, Endometrial Cancer
Phase 12004-03-01
TerminatedVaccine Therapy, Trastuzumab, and Vinorelbine in Treating Women With Locally Recurrent or Metastatic Breast Ca
Breast Cancer
Phase 22004-01-01
CompletedBiomarkers in Patients With Rectal Cancer Undergoing Chemotherapy and Radiation Therapy
Colorectal Cancer
2003-12-01
CompletedInduction Chemotherapy Using Paclitaxel, Carboplatin, CPT-11 With Pegfilgrastim
Non Small Cell Lung Cancer
Phase 22003-11-01
TerminatedCelecoxib in Treating Patients With Relapsed Prostate Cancer Following Radiation Therapy or Radical Prostatect
Prostate Cancer
Phase 22003-04-01
CompletedBortezomib, Fluorouracil, and External-Beam Radiation Therapy in Treating Patients With Stage II, Stage III, o
Colorectal Cancer
Phase 12003-04-01
CompletedRadiation Therapy During Surgery in Treating Older Women With Invasive Breast Cancer
Breast Cancer
N/A2003-03-18
CompletedMolecular Marker Profiling of Axillary Lymph Nodes in Predicting Response in Patients With Locally Advanced or
Breast Cancer
Phase 22002-05-01
CompletedDoxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or M
Breast Cancer, Leukemia, Lymphoma
Phase 1 / Phase 22001-05-01
CompletedTrastuzumab and External Beam Radiation Therapy in Treating Women With Stage III or Stage IV Breast Cancer
Breast Cancer
Phase 22000-03-01
WithdrawnGenistein in Treating Patients With Stage II, Stage III, or Stage IV Prostate Cancer
Prostate Cancer
Phase 11999-12-01
CompletedCapecitabine, Paclitaxel, and Trastuzumab in Treating Patients With Metastatic Breast Cancer
Breast Cancer
Phase 1 / Phase 21999-08-01
RecruitingCorrelation of Molecular Markers With Response to Therapy and Breast Cancer Behavior
Breast Cancer
1998-12-01
CompletedMultimodality Treatment for Women With Stage II, Stage III, or Stage IV Breast Cancer
Breast Cancer
Phase 21998-12-01
CompletedHigh-Dose Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refract
Breast Cancer
Phase 21997-09-01
CompletedCombination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced or Metastatic Cancer of the
Esophageal Cancer
Phase 1 / Phase 21997-03-01
No Longer AvailableCompassionate Use of CAR T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Swit
Acute Lymphoblastic Leukemia, Immune System Diseases, Immunoproliferative Disorders
No Longer AvailableCompassionate Use Re-Infusion of ATLCAR.CD30
Hodgkin Lymphoma, Adult