NCT04025229

High Intensity Interval Training in Endometrial Cancer

Pre-operative Window Study of Interval Exercise Training as a Therapy for Endometrial Cancer

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: UNC Lineberger Comprehensive Cancer Center · Academic / Other
• Sex: Female
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This interventional trial recruits women with endometrial cancer to participate in high intensity interval training (HIIT) prior to their standard of care surgery. The study will evaluate tissue and blood to determine if HIIT training has anti-cancer effects. P

Detailed description

Primary Objectives: 1\. Determine the anti-proliferative effect of HIIT on the endometrium of women with endometrial cancer 2. Participants will undergo baseline testing, be taught how to perform personalized HIIT training prior to surgery, and repeat testing after surgery. Tissue specimens will be collected from standard of care biopsy (no extra biopsy needed) and during surgery. Blood will be collected twice during standard of care blood draws.

Conditions

• Endometrial Cancer

Interventions

Type	Name	Description
BEHAVIORAL	HIIT exercise	High intensity interval training (4 to 6 sessions) prior to surgery

Timeline

• Start date: 2019-09-23
• Primary completion: 2024-09-08
• Completion: 2024-09-08
• First posted: 2019-07-18
• Last updated: 2025-10-15
• Results posted: 2025-08-24

Locations

1 site across 1 country: United States