NCT05743426

Disease Outcomes and Toxicities in Patients With Gastrointestinal and Sarcomatous Malignancies

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 180 (estimated)
• Sponsor: UNC Lineberger Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This prospective, single-institution, observational study explores disease outcomes and toxicities in subjects with gastrointestinal malignancies and sarcoma (bone and soft tissue) who are being treated with standard-of-care therapies including radiotherapy. Recent advances in treatment approaches affected disease outcomes and toxicities. Prospective monitoring of disease outcomes and toxicities using standardized assessments will provide information about recent changes in the standard of care and further refine treatment approaches and prospective clinical trial design.

Conditions

• Sarcoma
• Gastrointestinal Cancer

Interventions

Type	Name	Description
OTHER	Survey	Patient Reported Outcome (PRO) questionnaire
OTHER	Toxicity Assessments	Toxicity Assessments will be performed using the National Cancer Institute Common Terminology Criteria (NCI-CTCAE).

Timeline

• Start date: 2023-03-17
• Primary completion: 2036-01-01
• Completion: 2036-01-01
• First posted: 2023-02-24
• Last updated: 2026-03-30

Locations

1 site across 1 country: United States