NCT05414097

Finding Barriers and Designing Solutions to Promote Women s Cancer Screening in South Africa

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 348 (actual)
• Sponsor: UNC Lineberger Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The primary aim of the study explore drivers of cervical cancer screening and barriers contributing to low screening coverage among women in South Africa. Secondary aims are determining preferences for cervical cancer prevention services using a discrete choice experiment and developing a multi-level package of interventions that will address barriers to cervical cancer screening and improve engagement in care among women.

Detailed description

Cervical cancer is a leading cause of cancer death among South African women. Despite a comprehensive national cancer control policy, cervical screening coverage is low and attrition during on-ward referrals for diagnostic confirmation and treatment remains common. This study uses a sequential mixed-methods design: Phase 1) A qualitative exploratory phase using focus groups and in-depth interviews with women, men, other stakeholders will inform our design and interpretation of quantitative findings from a multi-cohort DCE. Phase 2) Women will be recruited to participate in the DCE and determine their preferences for cancer screening services. Phase 3) Design Thinking to co-create an intervention package for cervical cancer screening and enhanced linkage between screening, diagnosis, and treatment will be created.

Conditions

• Cervical Cancer

Interventions

Type	Name	Description
OTHER	Semi-structured focus group discussions - Women	Semi-structured focus group discussions to explore women's experiences with cervical cancer screening and treatment.
OTHER	semi-structured focus groups discussions - Men	Semi-structured focus group discussions to explore partner dynamics related to women's ability to access cancer screening.
OTHER	In-depth key stakeholders interviews	In-depth interviews to contextualise findings from women and men focus group discussions.
OTHER	Discrete Choice Experiment - Women	Discrete Choice Experiment to determine preferences to different cancer screening models.
OTHER	Development and User Pre-testing Workshops	Development and User Pre-testing Workshops to explore acceptability and feasibility of proposed interventions designed using findings from Phases 1 \&2.

Timeline

• Start date: 2022-07-16
• Primary completion: 2023-10-20
• Completion: 2023-10-20
• First posted: 2022-06-10
• Last updated: 2024-04-15

Locations

1 site across 1 country: South Africa