NCT01137643

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

Tissue Procurement For Hematolymphoid Conditions

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 15,000 (estimated)
• Sponsor: UNC Lineberger Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years – 120 Years
• Healthy volunteers: Not accepted

Summary

RATIONALE: Collecting and storing samples of tissue, blood, and body fluid from patients with cancer to study in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting and storing blood and tissue samples from patients being evaluated for hematologic cancer.

Detailed description

OBJECTIVES: * Provide source of patient tissue, blood, and body fluid samples for ongoing diagnostic, prognostic, or immune-monitoring studies. * Support and enhance translational, clinical and basic research for Lineberger Comprehensive Cancer Center (LCCC) members (and non-members who have an LCCC member as sponsor and collaborator) with IRB-approved studies. * Maintain responsible and appropriate policies and procedures that ensure good patient care and responsible conduct of research. * Address medical and legal issues, and protect participant and patient privacy and confidentiality. * Provide a responsible and uniform mechanism for the integrated coordination of the hemato-pathologist and surgeon or hematology/oncology staff, researcher, and protocol office to obtain appropriate specimens for researchers. * Support young investigators to obtain pilot data for grant funding. OUTLINE: Patients undergo tissue, blood, and body fluid collection during diagnostic or routine procedures for future correlative studies. Tissue samples may include, but are not limited to, lymph node or non-nodal biopsies, bone marrow biopsy and/or aspirate, blood and serum, and buccal swabs for germline DNA analysis.

Conditions

• Chronic Myeloproliferative Disorders
• Leukemia
• Lymphoma
• Lymphoproliferative Disorder
• Multiple Myeloma and Plasma Cell Neoplasm
• Myelodysplastic Syndromes
• Myelodysplastic/Myeloproliferative Neoplasms
• Nonmalignant Neoplasm

Interventions

Type	Name	Description
OTHER	biologic sample preservation procedure	All samples collected during routine clinical care.
OTHER	cytology specimen collection procedure	All Samples collected during routine clinical care.

Timeline

• Start date: 2009-07-01
• Primary completion: 2040-07-01
• Completion: 2040-07-01
• First posted: 2010-06-04
• Last updated: 2025-10-27

Locations

1 site across 1 country: United States