Trials / Terminated
TerminatedNCT02259452
Radiation Induced Cardiopulmonary Injury in Humans
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 91 (actual)
- Sponsor
- UNC Lineberger Comprehensive Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the study is to assess the time, dose dependence, and fraction-size dependence of radiation (RT)-induced changes in regional lung and heart perfusion/function/structure following thoracic RT delivered using newer IMRT/conformal/radiosurgery techniques. The PI hopes to develop models to better relate and predict RT-induced changes in regional lung and heart perfusion/function/structure with changes in global cardiopulmonary function. Patients will undergo pre- and serial post-RT lung and heart assessments to better understand RT-induced regional heart/lung changes.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | SPECT Lung Perfusion Scan | |
| PROCEDURE | SPECT Heart Perfusion Scan | |
| PROCEDURE | Pulmonary Function Tests |
Timeline
- Start date
- 2008-06-01
- Primary completion
- 2018-04-13
- First posted
- 2014-10-08
- Last updated
- 2020-02-26
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02259452. Inclusion in this directory is not an endorsement.