NCT04644419

Chemotherapy-related Cognitive Impairment and Acute Leukemia

Chemotherapy-related Cognitive Impairment in Adults With Acute Leukemia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 25 (actual)
• Sponsor: UNC Lineberger Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is an ancillary study of an intervention study (NCT04570709). The parent study is a single institution, feasibility trial of 20 (10 control and 10 intervention) patients with the primary objective of assessing feasibility, acceptability, and change in pre and post measures of symptoms, function, and quality of life by administering the Palliative and Collaborative Care InTervention (PACT). We will further assess cognitive function in the patients who participate in the control of the parent study.

Detailed description

The study objective is to observe patient-reported and researcher-assessed cognitive function in adults with acute myeloid leukemia with chemotherapy treatment. We will assess cognitive function using a battery of neuropsychological assessments, patient-reported questionnaire, and semi-structured interviews among participants in control group only. The group assignment will be conducted through parent study (NCT04570709). Participating in this study will not affect participants' group assignment.

Conditions

• Acute Myeloid Leukemia

Interventions

Type	Name	Description
OTHER	none (observational study)	This is an observational study and does not include intervention delivery.

Timeline

• Start date: 2020-11-03
• Primary completion: 2022-10-15
• Completion: 2023-05-03
• First posted: 2020-11-25
• Last updated: 2023-05-06

Locations

1 site across 1 country: United States