| Recruiting | Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response Prostate Adenocarcinoma, Iliac Nodal Disease, Para-aortic Lymph Node Metastasis | N/A | 2026-07-07 |
| Withdrawn | Antimicrobial Resistant Organism Decolonization After Microbiome Perturbation Gram-negative Bacteremia, Microbial Colonization, Antibiotic Resistant Infection | Phase 2 | 2026-07-01 |
| Not Yet Recruiting | Pneumonitis Prevention Protocol Using Pentoxifylline and α-tocopherol In Stage III Non-Small Cell Lung Cancer Non-Small Cell Lung Cancer, Radiation Induced Lung Injury (RILI) | Phase 2 | 2026-05-30 |
| Not Yet Recruiting | Clinical Trial to Test Efficacy of Targeting Hypoxia Combined With ARSI After First-line ARSI Therapy for Cast Castration Resistant Prostate Cancer | Phase 2 | 2026-05-27 |
| Not Yet Recruiting | Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvo Prostate Cancer (Adenocarcinoma) | Phase 2 | 2026-05-01 |
| Not Yet Recruiting | Fecal Microbiota Transplantation in Patients Undergoing Chimeric Antigen Receptor T-cell Therapy and Allogenei Lymphoma Receiving CAR-T Therapy | N/A | 2026-04-15 |
| Recruiting | Hypersight and Ethos In Pediatric Radiotherapy Cancer | N/A | 2026-04-14 |
| Not Yet Recruiting | Spinal Cord Stimulation for Refractory Pain Randomized Controlled Trial: the PAcStim RCT Chronic Pain Syndrome | N/A | 2026-04-01 |
| Not Yet Recruiting | ctDNA-Guided CURB for OPD mNSCLC on TKI (CURB-TKI) Metastatic NSCLC - Non-Small Cell Lung Cancer, OligoProgressive Metastatic Disease | Phase 2 | 2026-04-01 |
| Not Yet Recruiting | Cervicothoracic Sympathetic Block Evaluation for Post COVID Condition Autonomic Dysfunction | Phase 4 | 2026-04-01 |
| Not Yet Recruiting | Heart Rate VAriability as a MaRker for tItrATing hIgh flOw Nasal Cannula Therapy Respiratory Failure, Heart Rate Variability (HRV), High Flow Nasal Cannula | — | 2026-04-01 |
| Not Yet Recruiting | Clinical Trial to Observe the Effects of Tamoxifen on Testosterone Recovery in Medically Castrated Prostate Ca Hypogonadism, Prostate Cancer | Phase 2 | 2026-04-01 |
| Recruiting | Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and In Breast Cancer, Lung Cancer, Melanoma | — | 2026-03-31 |
| Not Yet Recruiting | Trial of a Virtual Exercise-based Rehabilitation Program to Treat Persistent Chemotherapy-Induced Peripheral N Chemotherapy-induced Peripheral Neuropathy (CIPN) | Phase 3 | 2026-03-30 |
| Not Yet Recruiting | BOLD-100 Plus Doxorubicin in Advanced Soft Tissue Sarcomas Sarcoma, Soft-tissue, Sarcoma, Sarcoma,Soft Tissue | Phase 1 | 2026-03-30 |
| Not Yet Recruiting | Renal Ex Vivo SYN002 Perfusion to Eliminate CMV Transmission Cytomegalovirus (CMV) Infection, Kidney Transplant Recipient | EARLY_Phase 1 | 2026-03-16 |
| Not Yet Recruiting | Ted Rogers Understanding of Exacerbations in Heart Failure 2: Monitor Heart Failure, Heart Failure - NYHA II - IV, Heart Failure Patients | — | 2026-03-16 |
| Not Yet Recruiting | Study of the Safety and Usefulness of Liposomal Curcumin in Multiple Myeloma Multiple Myeloma Refractory, Multiple Myeloma in Relapse | Phase 1 | 2026-03-02 |
| Not Yet Recruiting | Trauma-Focused Managing Cancer And Living Meaningfully (CALM-TF) for Newly Diagnosed and Recurrent Ovarian Can Ovarian Cancer (OvCa), Recurrent Ovarian Cancer | Phase 3 | 2026-03-01 |
| Recruiting | Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanom Cutaneous Melanoma, Melanoma Stage IV, Mucosal Melanoma | Phase 2 | 2026-02-27 |
| Recruiting | Efficacy of Biofeedback Training for Glaucoma Glaucoma, Biofeedback Training | N/A | 2026-02-10 |
| Not Yet Recruiting | Radiofrequency Ablation for Curative Treatment of Small Low-Risk Papillary Thyroid Cancer: Pilot Study Thyroid Papillary Carcinoma | N/A | 2026-02-05 |
| Not Yet Recruiting | A Comprehensive Multiomic Biomarker Evaluation Across Two Single-arm Cohorts to Elucidate Mechanisms of Respon Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma | Phase 2 | 2026-02-02 |
| Not Yet Recruiting | STEP2 vs. Routine Early Palliative Care: Randomized Noninferiority Trial Oncology | N/A | 2026-02-01 |
| Recruiting | Cannabinoids for Osteoarthritis Pain Effectiveness Trial Osteoarthritis of Knee, Osteoarthritis Hip | N/A | 2026-01-29 |
| Recruiting | Feasibility of a Cognitive Stepped Care Program for Adults With Brain Metastases Brain Metastases, Brain Metastasis | N/A | 2026-01-09 |
| Not Yet Recruiting | Semaglutide for the Prevention Of Post-Transplant Diabetes Mellitus Kidney Transplant Recipient | Phase 2 / Phase 3 | 2026-01-05 |
| Recruiting | Feasibility and Safety of a Combined Augmented Reality and Functional Electrical Stimulation System Cervical Spinal Cord Injury | EARLY_Phase 1 | 2026-01-01 |
| Recruiting | Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine Trial - Effect of Hyperbaric Oxygen Long COVID, Post Acute Sequelae of COVID-19, Post-COVID-19 Condition | N/A | 2026-01-01 |
| Recruiting | Innovative Approaches to Enhance Balance and Neuroplasticity in Multiple Sclerosis Multiple Sclerosis, Mobility Limitation, Balance; Distorted | N/A | 2025-12-30 |
| Recruiting | Combination Letermovir and Standard of Care Antiviral for Enhanced Antiviral Response in Cytomegalovirus Infec CMV, Lung Transplant Recipient | Phase 4 | 2025-12-24 |
| Recruiting | LIFUS For Neurological Disorders Parkinson's Disease (PD), Essential Tremor, Orthostatic Tremor | N/A | 2025-12-02 |
| Not Yet Recruiting | Virtual Vs Telephone Education in Radiotherapy Patient Education, Radiotherapy | N/A | 2025-12-01 |
| Recruiting | Lattice Radiation Therapy Versus Conventional Radiation Therapy for the Palliation of Large Tumors Histopathologically or Cytologically Confirmed Solid Tumor Who Require Palliation Radiation Therapy to a Lesion ≥5cm | Phase 3 | 2025-11-18 |
| Recruiting | Study to Assess the Safety and Effects of Porphysome Nanoparticles for Imaging in Gynaecological Cancers Gynecological Cancers | Phase 1 | 2025-11-18 |
| Recruiting | Pandemic Influenza Vaccine in Organ Transplantation (PIVOT Trial) Influenza (Pandemic), Avian Influenza, Vaccination | Phase 3 | 2025-11-03 |
| Not Yet Recruiting | Prospective Reduction Of Transplant Complications Through Enhanced Preservation Therapy to Prevent Primary Gra Primary Graft Dysfunction | N/A | 2025-11-01 |
| Recruiting | Intraoperative Navigation for Surgically Precise Resection of the Chest (INSPIRE) Thoracic Wall | N/A | 2025-11-01 |
| Recruiting | Phase II Study of Daily Adaptive Radiotherapy for Submandibular Gland-sparing in Head and Neck Cancer Squamous Cell Cancer of Head and Neck (SCCHN) | N/A | 2025-10-15 |
| Not Yet Recruiting | 68Ga-FAPI PET/CT in the Staging of High-Grade Epithelial Ovarian Cancers: A Pilot Study High Grade Serous Ovarian Cancer (HGSOC) | N/A | 2025-09-25 |
| Recruiting | Combined Light, ExVivo, and Antivirals for Recipients of Lungs From HBV Donors Hepatitis B Virus (HBV), Lung Transplant Recipient | Phase 4 | 2025-09-24 |
| Recruiting | AI and Safety in Laparoscopic Cholecystectomy: A Randomized Controlled Trial Laparoscopic Cholecystectomy | Phase 3 | 2025-09-17 |
| Not Yet Recruiting | OMERACT SLE Delphi SLE - Systemic Lupus Erythematosus | — | 2025-09-15 |
| Recruiting | A Trial of ABSK043, an Oral PD-L1 Inhibitor, in Patients With Angiogenic Sarcomas Sarcoma | Phase 2 | 2025-09-09 |
| Recruiting | Sentinel lympH Node Biopsy With Indocyanine Green in Breast Cancer After NEoadjuvant Chemotherapy (SHINE) Breast Cancer | N/A | 2025-09-03 |
| Not Yet Recruiting | Autologous Cold-stored Apheresis Platelets Bleeding, Platelets, Cardiopulmonary Bypass | Phase 2 / Phase 3 | 2025-09-01 |
| Not Yet Recruiting | Modafinil and Exercise for Post Stroke Fatigue Stroke, Fatigue, Modafinil | Phase 3 | 2025-09-01 |
| Not Yet Recruiting | Peri-procedural Management of Direct Oral Anticoagulants for Central VENOus Catheters in CAncer Patients With Anticoagulant-induced Bleeding, Direct Oral Anticoagulant, Cancer | N/A | 2025-09-01 |
| Recruiting | Study of How Safe and Effective Tarlatamab is in Brain Cancers Astrocytic Tumor, Oligodendroglial Tumor | Phase 2 | 2025-08-18 |
| Recruiting | Effect of Hi-OxSR for the Treatment of Post COVID Condition Long COVID, Post COVID-19 Condition, Post Acute Sequelae of COVID-19 | N/A | 2025-08-01 |
| Not Yet Recruiting | Weight-loss Drug for Fertility-Sparing Treatment of Atypical Hyperplasia and Low-grade Cancer of the Endometri Endometrial Cancer, Atypical Hyperplasia | Phase 2 | 2025-08-01 |
| Recruiting | Consolidative Use of Radiotherapy to Block Oligoprogression in Patients With Metastatic Melanoma Metastatic Melanoma, OligoProgressive Metastatic Disease | N/A | 2025-07-24 |
| Recruiting | Stereotactic Body Radiotherapy or Standard of Care for Prostate Oligoprogressive Cancer Castrate Resistance Prostate Cancer, OligoProgressive Metastatic Disease | Phase 2 | 2025-07-08 |
| Not Yet Recruiting | Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Adv Caregiver Distress | Phase 2 | 2025-07-02 |
| Not Yet Recruiting | Time-effect of FEST+TST in the Upper-extremity Rehabilitation of Individuals with Traumatic SCI Spinal Cord Injuries | N/A | 2025-07-01 |
| Not Yet Recruiting | Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane Oxygenation Respiratory Failure | N/A | 2025-07-01 |
| Recruiting | To Assess Safety of Mitapivat and Provide Proof of Concept of the Efficacy of the Drug in Patients With RBC Me Anemia | Phase 2 | 2025-06-26 |
| Recruiting | Study of NABPLAGEM vs. Nab-Paclitaxel/Gemcitabine in BRCA1/2 or PALB2 Pancreatic Cancer Pancreatic Cancer, Advanced or Metastatic, BRCA1/2 Mutation, PALB2 Gene Mutation | Phase 2 / Phase 3 | 2025-06-10 |
| Recruiting | A Study to Evaluate Zanubrutinib and Tislelizumab in Progressive Lymphoma Post CAR-T Large B-cell Lymphoma | Phase 2 | 2025-06-04 |
| Not Yet Recruiting | Buccal Fat for Transoral Robotic Lateral Oropharyngectomy Defects to and Postoperative Pain Tonsil Neoplasm, Oropharynx Neoplasm, Transoral Robotic Surgery | Phase 2 | 2025-06-01 |
| Recruiting | Canada-wide Implementation of a Virtual Sexual Health and Rehabilitation eClinic (SHAReClinic) for Prostate Ca Prostate Cancer, Sexual Dysfunction, Physiological, Sexual Dysfunction, Psychological | — | 2025-06-01 |
| Active Not Recruiting | Validation of Fitbit Measurements in Hospitalized General Medicine Patients GIM Diagnosis, Medicine, Admission to GIM | — | 2025-06-01 |
| Recruiting | Psychoeducation for AlloHCT Caregivers Cancer, Caregivers, Stem Cell Transplant | N/A | 2025-05-21 |
| Recruiting | Stimulating Postural Control to Augment Rehabilitation After Cerebral Stroke (SPARC): a Pilot Trial Stroke | N/A | 2025-05-21 |
| Recruiting | Chemoimmunotherapy Followed by Surgery for Oligometastatic Esophagogastric Cancer: (TORO Protocol) Esophageal Cancer, Gastric Cancer, Oligometastatic Disease | N/A | 2025-05-09 |
| Recruiting | Deep Brain Stimulation of the Pedunculopontine Nucleus for Alzheimer's Disease Alzheimer Disease | N/A | 2025-05-01 |
| Recruiting | Micro-ultrasound-Guided Focal Laser Ablation for Intermediate-Risk Prostate Cancer: Safety & Effectiveness Prostate Cancer (Adenocarcinoma), Low and Intermediate Risk Prostate Cancer | N/A | 2025-04-30 |
| Recruiting | PET/MR Scan With [68Ga]Ga-PentixaFor (CXCR4) vs Standard of Care (SOC) for Initial Staging and Follow up in Mu Multiple Myeloma | N/A | 2025-04-22 |
| Recruiting | HN-BIO 02: A Phase II Randomized Study of the Effects of Delayed Elective Radiotherapy on Head and Neck MRI an Squamous Cell Carcinoma of Head and Neck | N/A | 2025-04-17 |
| Recruiting | EXtubation Related Complications - the EXTUBE Study (EXTUBE) Extubation | — | 2025-04-14 |
| Recruiting | Dual PSMA and FDG PET Imaging for Patients With Advanced Prostate Cancer Advanced Prostate Cancer | N/A | 2025-04-03 |
| Recruiting | Post-operative Intravenous Iron to Treat Iron-deficiency Anemia in Patients Undergoing Cardiac Surgery Chronic Iron Deficiency Anaemia, Cardiac Surgery | Phase 2 | 2025-04-03 |
| Completed | Pilot Trial of Virtual and In-person STEP2 Oncology | N/A | 2025-03-27 |
| Not Yet Recruiting | Relationship of Point-of-care Coagulation Assays with Clinical Outcomes in Cardiac Surgery: a Retrospective Co Cardiac Surgery Requiring Cardiopulmonary Bypass | — | 2025-03-15 |
| Recruiting | A Study of High Dose Radiation Therapy for Locally Advanced Pancreatic Cancer That Responded to Initial Chemot Locally Advanced Pancreatic Adenocarcinoma | Phase 2 | 2025-03-12 |
| Withdrawn | IL-1 Inhibition in Early TNBC Early Stage Triple Negative ER Low Breast Cancer | Phase 2 | 2025-03-05 |
| Not Yet Recruiting | Topical TRanexamic Acid Vs. Placebo on Acute Postoperative Pain Following DRF Fixation Distal Radius Fractures | Phase 4 | 2025-03-01 |
| Not Yet Recruiting | Using Tumor Models to Determine Treatments Pancreatic Ductal Carcinoma, Advanced Cancer, Epithelial Tumor | Phase 2 | 2025-02-17 |
| Recruiting | Emotion and Symptom-Focused Engagement (EASE) for Caregivers Trauma and Stressor Related Disorders, Pediatric Cancer, Caregiver Burden | N/A | 2025-02-14 |
| Recruiting | VR&R: Providing Caregiver Respite by Managing BPSDs and Improving QoL in People with Dementia Using Immersive Dementia | N/A | 2025-02-12 |
| Recruiting | Is Adaptive SBRT for Prostate vs Image-guided Radiotherapy a True Evolution (ASPIRE) Localized Prostate Cancer, Stereotactic Body Radiotherapy | Phase 3 | 2025-02-04 |
| Not Yet Recruiting | Effectiveness of AV-stimulation in Immersive VR to Improve Visual Perception and Driving Performance Stroke, Visual Impairment, Low Vision | N/A | 2025-02-01 |
| Recruiting | BAL Fluid Biomarkers in Sarcoma Soft Tissue Sarcoma (STS), Bronchoalveolar Lavage (BAL), Bronchoalveolar Lavage Fluid | Phase 2 | 2025-01-29 |
| Recruiting | Feasibility Trial of Glofitamab in a Response Adapted Approach Incorporating Interim FDG PET and ctDNA to Opti Diffuse Large B Cell Lymphoma (DLBCL) | Phase 2 | 2025-01-24 |
| Not Yet Recruiting | Preventing Delayed Graft Function in Kidney Transplant Patients Kidney Transplant, Kidney Failure, Kidney Injury | N/A | 2025-01-15 |
| Not Yet Recruiting | Point of Care Ultrasound in Pregnant Women (PoCUS-OB) Obstructive Sleep Apnea (OSA) | — | 2025-01-15 |
| Enrolling By Invitation | EXercise Enhancement After RadioTherapy for Bone Metastases Bone Metastases | N/A | 2025-01-13 |
| Recruiting | Improving Patient Sleep Prior to Elective Surgery Surgery | N/A | 2025-01-03 |
| Recruiting | Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA Osteoarthritis, Knee | Phase 2 / Phase 3 | 2025-01-01 |
| Not Yet Recruiting | Validation of a Novel Handheld Device for Accurate Cricoid Pressure in Healthy Volunteers Cricoid Pressure | — | 2025-01-01 |
| Recruiting | Dose Efficacy in Adhesive Capsulitis Adhesive Capsulitis of the Shoulder | Phase 3 | 2024-12-20 |
| Not Yet Recruiting | Gemcitabine/Cisplatin/Nab-Paclitaxel and Rilvegostomig in Resectable iCCA Cholangiocarcinoma Resectable | Phase 2 | 2024-12-15 |
| Recruiting | Belimumab in Autoimmune Hepatitis Autoimmune Hepatitis | Phase 2 | 2024-12-11 |
| Recruiting | Radialis PET Imager for the Assessment of Neuritic Amyloid Plaque Burden Cognitive Impairment | N/A | 2024-12-06 |
| Recruiting | Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fra Liver Metastases | Phase 3 | 2024-12-05 |
| Active Not Recruiting | Vitamin D Metabolites as Biomarkers for the Identification of Kidney Injury in Cardiac Surgery Acute Kidney Injuries, Chronic Renal Diseases | — | 2024-12-02 |
| Recruiting | Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before Transplant Hepatocellular Carcinoma (HCC), Macrovascular Invasion, Liver Transplant Surgery | Phase 1 / Phase 2 | 2024-12-01 |
| Recruiting | Comparing Moderately Ultra Hypofractionated Radiation Treatments for Prostate Cancer Post-Operative Prostate Cancer | Phase 2 | 2024-11-26 |
| Recruiting | Plan Development for Giving Teclistamab in the Outpatient Setting Multiple Myeloma, Relapsed Cancer, Refractory Cancer | Phase 4 | 2024-11-19 |
| Recruiting | Evaluation of a Supportive Housing Program for Adults Who Are Unhoused and Have Complex Health Needs Homeless Persons | N/A | 2024-11-06 |
| Recruiting | Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression Bipolar Depression | Phase 1 | 2024-10-09 |
| Recruiting | RSV Vaccine in Transplant Recipients Vaccine Response Impaired, Respiratory Syncytial Virus Infections, Immune Suppression | Phase 3 | 2024-10-01 |
| Completed | FES Implementation Pediatrics Cerebral Palsy (CP) | N/A | 2024-10-01 |
| Terminated | --SuPERIOR Trial-- Non-Small Cell Lung Cancer (NSCLC), Clinical Staging T2b-3 N0-1 M0 | Phase 2 | 2024-09-28 |
| Not Yet Recruiting | Feasibility of a Telemonitoring Program for Pregnant Women at High-Risk for Preeclampsia in Pakistan Preeclampsia, Pregnant With Complication | N/A | 2024-09-01 |
| Recruiting | meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis Peritoneal Dialysis Complication, End Stage Kidney Disease, Sodium-glucose Co-transporter-2 Inhibitors | Phase 3 | 2024-09-01 |
| Recruiting | Digital Peer Navigation for Adolescents and Young Adults With Cancer Lymphoma, Breast Cancer, Testicular Cancer | N/A | 2024-08-27 |
| Recruiting | Cognitive Health Awareness Program in Surgical Patients Dementia, Cognitive | N/A | 2024-08-12 |
| Recruiting | Salvage MR-guided High-Dose-Rate Brachytherapy for Prostate Bed Recurrence After Radiotherapy in the PSMA PET Prostate Cancer Recurrent, Prostate Cancer | N/A | 2024-08-08 |
| Recruiting | Inspiratory Muscle Training in Lung Transplant Candidates Inspiratory Muscle Training | N/A | 2024-08-06 |
| Recruiting | COgnitive-somatoSensory-MOtor Training to Improve Arm and Hand Function After Stroke (iCOSMO) Stroke, CVA, Cerebrovascular Accident | N/A | 2024-08-01 |
| Recruiting | Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy Myelodysplastic Syndrome, Acute Myeloid Leukemia | — | 2024-08-01 |
| Recruiting | Greater Occipital Nerve Block for Spontaneous Intracranial Hypotension Spontaneous Intracranial Hypotension | — | 2024-08-01 |
| Recruiting | Long Term Cardiovascular Disease Event Risk for Patients Undergoing Major Non-Cardiac Surgery Cardiovascular Diseases, Risk Reduction Behavior | — | 2024-08-01 |
| Active Not Recruiting | Hypobaric L5-S1 Study Anesthesia, Anesthesia, Local | — | 2024-07-22 |
| Recruiting | Diagnosis of Graft Pathology by TruGraf Acute Graft Rejection | — | 2024-07-20 |
| Recruiting | Early Palliative Care for Patients With Multiple Myeloma and Aggressive Lymphoma Multiple Myeloma in Relapse, Multiple Myeloma, Refractory, Multiple Myeloma Stage III | N/A | 2024-07-18 |
| Active Not Recruiting | PASS Pain After Surgery Analgesia | — | 2024-07-11 |
| Not Yet Recruiting | Study of Radiation Therapy in Combination With Darolutamide + Degarelix in Intermediate Risk Prostate Cancer Prostate Cancer | Phase 2 | 2024-07-02 |
| Recruiting | A Study to Test the Benefit of Vitamin B5 in Patients With Melanoma Melanoma (Skin) | Phase 1 | 2024-06-24 |
| Active Not Recruiting | Albumin Utilization in Adult Cardiac Surgical Patients : A Multicentre Prospective Cohort Study Antithrombin III Levels, Albumin Levels | — | 2024-06-11 |
| Recruiting | Feasibility of CALM in Patients With Ovarian Cancer Patient Satisfaction, Ovarian Cancer | N/A | 2024-06-10 |
| Active Not Recruiting | Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer Advanced Cancer, Stage IV Solid Tumor Cancer, Stage IV Sarcoma of Bone | Phase 2 | 2024-06-06 |
| Recruiting | Delayed Cold-Stored Platelets -PLTS-1 Platelets, Bleeding, Cardiopulmonary Bypass | Phase 2 | 2024-06-05 |
| Not Yet Recruiting | TRanEXamic Acid to Decrease Heavy Menstrual Bleeding in Individuals Anticoagulated for Venous Thromboembolism Venous Thromboembolism, Venous Thromboses, Heavy Menstrual Bleeding | Phase 4 | 2024-06-01 |
| Not Yet Recruiting | Azoles Targeting Recurrent High Grade Gliomas Brain Tumor, Recurrent, Cancer, Advanced, Glioma of Brain | EARLY_Phase 1 | 2024-06-01 |
| Not Yet Recruiting | Visual Telerehabilitation in Children, Adolescents and Young Adults With Hemianopsia Consecutive to a Brain Tu Hemianopsia | N/A | 2024-06-01 |
| Completed | Evaluating the Impact of Virtual Reality Exposure Therapy on Epilepsy/Seizure-Specific Interictal Anxiety Epilepsy, Anxiety Disorders | N/A | 2024-05-24 |
| Completed | Peer Support Group for Adolescent and Young Adult (AYA) Allogeneic Stem Cell Transplant Recipients Cancer, Leukemia, Stem Cell Transplant | N/A | 2024-05-24 |
| Active Not Recruiting | Albumin Utilization in Adult Cardiac Surgical Patients: Retrospective Cardiovascular Surgical Procedures, Albumin | — | 2024-05-23 |
| Recruiting | A Pan-Canadian, Investigator Initiated Clinical Trial With Focal IRE Directed to Intermediate-Risk Prostate Ca Prostate Cancer | N/A | 2024-05-16 |
| Recruiting | M. Avium WGS During Mav-PD Treatment Mycobacterium Avium, Mycobacterium Infections, Nontuberculous, Mycobacterium Infections | — | 2024-05-13 |
| Not Yet Recruiting | EASE-SOT Pilot Study Transplant;Failure,Kidney, Transplant; Failure, Heart, Transplant; Failure, Liver | N/A | 2024-05-01 |
| Active Not Recruiting | Exercise-based Rehabilitation to Treat Persistent Chemotherapy Induced Peripheral Neuropathy (CIPN) Chemotherapy-induced Peripheral Neuropathy | Phase 1 | 2024-04-25 |
| Recruiting | CfDNA in Hereditary And High-risk Malignancies 2 Hereditary Cancer Syndrome | — | 2024-04-19 |
| Recruiting | Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty Chronic Pain, Knee Pain Chronic, Post Operative Pain | Phase 2 | 2024-04-16 |
| Recruiting | Remote Monitoring of Patient Reported Outcomes to Improve the Efficacy of the Acute Phase Radiotherapy Review Prostate Cancer, Breast Cancer | N/A | 2024-04-09 |
| Withdrawn | Optimizing Lymphodepletion to Improve Outcomes in Patients Receiving Cell Therapy With Kymriah Lymphoma, Large B-Cell, Diffuse | Phase 1 | 2024-04-05 |
| Not Yet Recruiting | Acellular Dermal Allograft for Chronic Diabetic Wounds Wound Heal, Diabetic Foot Ulcer | N/A | 2024-04-01 |
| Unknown | RCT of Gut-directed Hypnotherapy in Ehlers-Danlos Syndromes and Generalized Hypermobility Spectrum Disorders Ehlers-Danlos Syndrome, Irritable Bowel Syndrome, Hypermobility Syndrome | N/A | 2024-04-01 |
| Active Not Recruiting | The Semaglutide Study Fasting | — | 2024-03-25 |
| Active Not Recruiting | Phase 1 Study of RP-6306 With Carboplatin and Paclitaxel in TP53 Ovarian and Uterine Cancer Recurrent Ovarian Cancer, Recurrent Uterine Cancer, Metastatic Cancer | Phase 1 | 2024-03-20 |
| Recruiting | Vaccinal Effect of HBsAg Monoclonal Ab VIR-3434 in Chronic Hepatitis B Infection [VISION] Hepatitis B, Chronic | Phase 2 | 2024-03-13 |
| Active Not Recruiting | Margin Intraoperative CT Feedback Feedback Study Lung Cancer (Diagnosis) | N/A | 2024-03-06 |
| Recruiting | IVIM & OLINK in Sarcoma Soft Tissue Sarcoma | Phase 2 | 2024-03-05 |
| Recruiting | Older Adults With Cognitive Impairment Doing Sit to Stands, Walking in Transitional Care Programs: A Feasibili Cognitive Impairment, Dementia, Delirium | N/A | 2024-03-01 |
| Unknown | Sleep Apnea in Paralympic Ontario-Resident aThletes With Spinal Cord Injury (SPORTS) Study Sleep Apnea, Breathing Disorder During Sleeping, Sleep Disorder | N/A | 2024-02-20 |
| Recruiting | Emotion and Memory in Chronic Neuropathic Pain Trigeminal Neuralgia, Facial Pain | — | 2024-02-12 |
| Recruiting | Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psiloc Major Depressive Disorder, Depression, Treatment-Resistant Depression | Phase 2 | 2024-02-05 |
| Recruiting | Umbrella Study for Single Patient Treatments in Oncology Advanced Cancer, Rare Diseases | — | 2024-02-01 |
| Unknown | Pilot Study on Trametinib for Surgical Unruptured AVMs Arteriovenous Malformations | Phase 2 | 2024-01-30 |
| Recruiting | A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers Squamous Cell Carcinoma of Head and Neck | N/A | 2024-01-29 |
| Completed | Online Psychology Program for Chronic Pain After Surgery Post-surgical Pain, Pain, Acute, Pain, Chronic | N/A | 2024-01-20 |
| Withdrawn | Non-linear Multimodal Microendoscopy for Lung Cancer Pathology Lung Cancer | — | 2024-01-11 |
| Recruiting | i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Cl Major Depressive Disorder, Suicide, Treatment Resistant Depression | Phase 2 | 2024-01-02 |
| Recruiting | Feasibility of Reducing Respiratory Drive Using the Through-flow System Respiratory Insufficiency, Diaphragm Injury, Lung Injury | N/A | 2024-01-01 |
| Enrolling By Invitation | Conversion of Maintenance Prograf to Envarsus in Liver Transplant Recipients Liver Transplant Rejection, Immune System Suppression | Phase 4 | 2024-01-01 |
| Recruiting | The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A M Heart Failure, Cardiotoxicity, Cancer | N/A | 2024-01-01 |
| Recruiting | ODYSSEE Kidney Health Trial Chronic Kidney Diseases | N/A | 2023-12-13 |
| Recruiting | Feasibility of Early Swallowing and Speech Intervention for Head and Neck Cancer Patients Treated SURGically Dysphagia, Head and Neck Cancer | N/A | 2023-12-01 |
| Recruiting | Study to Investigate an Association Between Brain Activity and Tidal Volume in Humans (BATMAN) Ventilation Therapy; Complications | N/A | 2023-11-30 |
| Recruiting | Durvalumab and Oleclumab in Resectable PDAC Pancreatic Ductal Adenocarcinoma | Phase 2 | 2023-11-29 |
| Recruiting | Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Dementia, Alzheimer Disease, Dementia With Lewy Bodies | — | 2023-11-11 |
| Recruiting | Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms Myeloproliferative Neoplasm | Phase 2 | 2023-11-08 |
| Completed | A Novel Combined Neuromodulation Therapy to Enhance Balance and Neuroplasticity Spinal Cord Injuries, Muscle Pareses, Fall | N/A | 2023-11-05 |
| Terminated | Re:Garde Program - Training and Maintaining Visual Perception in Older Adults Vision, Low, Visual Impairment | N/A | 2023-10-26 |
| Recruiting | Durvalumab and Tremelimumab in Resectable HCC Hepatocellular Carcinoma | Phase 2 | 2023-10-26 |
| Recruiting | The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Recept Kidney Transplant Recipients | Phase 2 | 2023-10-24 |
| Recruiting | Short Antibiotic Treatment in High Risk Febrile Neutropenia Febrile Neutropenia | N/A | 2023-10-01 |
| Withdrawn | A Study of Adaptive Radiation Therapy for Pelvic Genitourinary Cancer Prostate Cancer, Bladder Cancer | N/A | 2023-10-01 |
| Recruiting | MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach Anal Squamous Cell Carcinoma | Phase 2 | 2023-09-29 |
| Recruiting | Positron Emission Mammography and Liquid Biopsy in Women With High-risk Breast Screenings Breast Cancer | N/A | 2023-09-21 |
| Unknown | Pain Phenotyping in Knee OA: a Pilot Trial Osteo Arthritis Knee, Chronic Post-operative Pain | — | 2023-09-18 |
| Recruiting | CHARM-COPD Program of Care Chronic Obstructive Pulmonary Disease | N/A | 2023-09-15 |
| Active Not Recruiting | Detect CI (Cognitive Impairment) Study Cognitive Impairment (CI) | — | 2023-09-15 |
| Unknown | Sleeve Gastrectomy for Morbid-Obesity Sequelae After Transplantation Liver Transplantation, Obesity | N/A | 2023-09-01 |
| Recruiting | Comparing Menghini-type Needle and Franseen-type Needle in EBUS-TBNA for Sarcoidosis Suspected Sarcoidosis | N/A | 2023-08-18 |
| Unknown | Conventional-therapy & FES-therapy In-Veritas Effects Study C5 Palsy | N/A | 2023-08-16 |
| Active Not Recruiting | Study of Hydroxychloroquine With FOLFIRI and Bevacizumab in DTP-high Metastatic Colorectal Cancer Metastatic Colorectal Cancer | Phase 2 | 2023-08-09 |
| Recruiting | Consolidative Prostate Radiotherapy in Metastatic Prostate Cancer Prostate Metastases | Phase 2 | 2023-08-09 |
| Active Not Recruiting | Towards Noninvasive DBS of the Basal Ganglia in Parkinson's Disease Using TUS Parkinson Disease, Dystonia | N/A | 2023-08-01 |
| Recruiting | Toronto Western Hospital (TWH) Waste Audit Audit of Medical Waste Disposal | — | 2023-07-27 |
| Recruiting | HN-QUEST: A Study of Head and Neck Imaging Biomarkers Head and Neck Squamous Cell Carcinoma | N/A | 2023-07-26 |
| Recruiting | Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small Lymphocytic Lymphoma | Phase 1 | 2023-07-26 |
| Active Not Recruiting | Comprehensive Health Assessment for my Cancer Treatment Plan Cancer, Older Adults | N/A | 2023-07-24 |
| Recruiting | Optimizing lymphoDepletion to Improve Outcomes In Patients Receiving Cell Therapy With Yescarta DLBCL - Diffuse Large B Cell Lymphoma | Phase 1 | 2023-07-14 |
| Recruiting | Molecular Residual Disease Interception in Locoregionally-Advanced High Risk HPV+ and HPV- HNSCC Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA-HNSCC) | Phase 2 | 2023-07-12 |
| Unknown | Patent Foramen Ovale (PFO) and Risk of Perioperative Stroke Patent Foramen Ovale | — | 2023-07-07 |
| Recruiting | Virtual Rehabilitation for Cancer Survivors Breast Cancer, Stage 0, Colorectal Cancer Stage I, Head and Neck Cancer Stage I | N/A | 2023-07-07 |
| Withdrawn | Nurse-performed Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax. Pneumothorax, Cardiac Surgery | — | 2023-07-01 |
| Recruiting | Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE) Breast Cancer, Breast Cancer Recurrent | N/A | 2023-06-27 |
| Recruiting | At-home Breast Oncology Care Delivered With E-health Solutions Patient Engagement, Patient Activation, Patient Reported Outcome Measures | N/A | 2023-06-22 |
| Recruiting | Effectiveness of Digital Cognitive Behavioral Therapy for Insomnia in Frontline Health Care Workers (The HCW-C Insomnia, Post Traumatic Stress Disorder, Anxiety Disorders | N/A | 2023-06-16 |
| Unknown | Effects of Peripheral Electrical Stimulation With Focused Ultrasound on Motor Symptoms in Parkinson's Patients Parkinson Disease | N/A | 2023-06-13 |
| Completed | Spinal Hypobaric Local Anesthetic Study Anesthesia, Local | — | 2023-06-09 |
| Active Not Recruiting | 10°C vs 4°C Lung Preservation RCT Lung Transplant, Organ Preservation | N/A | 2023-06-09 |
| Recruiting | Seronegative Myasthenia Gravis - Efgartigimod IV Efgartigimod, Generalized Myasthenia Gravis | Phase 3 | 2023-06-01 |
| Completed | RECLAIM: Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine Long COVID, Post COVID Condition, Post Acute Sequelae of COVID-19 | Phase 2 / Phase 3 | 2023-05-31 |
| Recruiting | Duration of Androgen Receptor Pathway Inhibitor and ADT With Metastasis Directed Therapy in Oligometastatic Ca Metastatic Prostate Cancer | Phase 2 | 2023-05-24 |
| Recruiting | TOward a comPrehensive Supportive Care Intervention for Older Men With Metastatic Prostate Cancer Metastatic Prostate Cancer | N/A | 2023-05-23 |
| Unknown | Investigating LFP Correlates of TUS in Patients With Movement Disorders Parkinson Disease, Essential Tremor, Dystonia | N/A | 2023-05-18 |
| Completed | Virtual Sport for Adults ≥ 50 Years With Spinal Cord Injury Spinal Cord Injury | N/A | 2023-05-05 |
| Recruiting | Platform of Randomized Adaptive Clinical Trials in Critical Illness Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High | N/A | 2023-04-30 |
| Recruiting | Respiratory Muscle Structure and Function in Mechanically Ventilated Patients and Long-term Outcomes Mechanical Ventilation Complication, Diaphragm Injury, Lung Injury | — | 2023-04-27 |
| Recruiting | The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer Thyroid Nodule, Thyroid Cancer | N/A | 2023-04-20 |
| Active Not Recruiting | Symptom Management in Patients on Dialysis End-stage Kidney Disease | N/A | 2023-04-19 |
| Unknown | REmote moBile Outpatient mOnitoring in Transplant 2.0 Solid Organ Transplant, Heart Transplant, Liver Transplant | N/A | 2023-04-01 |
| Completed | Evaluation of FES+VFBT With Individuals With Lived Experience Spinal Cord Injuries, Stroke | N/A | 2023-04-01 |
| Recruiting | PET-MRI Esophagus Feasibility Study Esophagogastric Cancer | N/A | 2023-03-28 |
| Completed | Pilot to Evaluate VR-Therapy on People With Epilepsy and Related Anxiety Epilepsy, Anxiety Disorders and Symptoms | N/A | 2023-03-24 |
| Recruiting | End-on Versus Parallel Radiofrequency Lesioning for Neurotomy of the Cervical Medial Branch Nerves Neck Pain, Zygapophyseal Joint Arthritis | N/A | 2023-03-10 |
| Active Not Recruiting | Province of Ontario Strategy for Personalized Management of Pancreatic Cancer Trial Pancreas Cancer | — | 2023-03-06 |
| Recruiting | Cerebellar Deep Brain Stimulation for the Treatment of Ataxia Ataxia, Gait | N/A | 2023-03-02 |
| Unknown | Quantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Trans Hypertrophic Obstructive Cardiomyopathy | Phase 4 | 2023-03-01 |
| Unknown | Using Genetic Profile to Determine the Treatment for Patients With Ovarian Cancer Who Previously Received a PA Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer | Phase 2 | 2023-02-23 |
| Recruiting | In Vivo Lung Perfusion (IVLP) for Colorectal Cancer Metastatic to Lung Lung Metastases, Colorectal Cancer Metastatic, Colorectal Cancer | Phase 1 | 2023-02-06 |
| Active Not Recruiting | MR-guided Tumour Boost Prostate Cancer | N/A | 2023-02-06 |
| Completed | Feasibility of Transvenous Phrenic Nerve Stimulation for Diaphragm Protection in Acute Respiratory Failure Acute Hypoxemic Respiratory Failure, Diaphragm Injury, Lung Injury | N/A | 2023-02-04 |
| Completed | Effectiveness of Rehabilitation in Adults Suffering From Persistent Concussion Symptoms Postconcussion Syndrome, Mild Traumatic Brain Injury | N/A | 2023-01-30 |
| Active Not Recruiting | The Use of Indocyanine Green to Visualize Blood Flow to the Gastrojejunostomy During Bariatric Surgery. Ulcer, Gastric, Obesity, Morbid | Phase 4 | 2023-01-25 |
| Recruiting | The Lullaby Project as a Musical Intervention for Pregnant Individuals With Epilepsy Epilepsy, Pregnancy Related | N/A | 2023-01-23 |
| Recruiting | Intravenous vs Oral Acetaminophen in Postoperative Hip Fracture Adult Patients Hip-fracture, Surgery | Phase 4 | 2023-01-23 |
| Active Not Recruiting | Blood Salvage in Orthotopic Liver Transplantation With HCC Hepatocellular Carcinoma, Surgery | N/A | 2023-01-21 |
| Unknown | Subgenual Cingulate Deep Brain STIMulation for Apathetic Behavioral Variant FRONtotemporal Dementia Frontotemporal Dementia, Deep Brain Stimulation | N/A | 2023-01-12 |
| Terminated | Sentry Study: Raman Spectroscopy on Ex Vivo Lungs Lung Cancer | N/A | 2023-01-09 |
| Withdrawn | Study to Measure and Enhance the Health Related Quality Of Life in Cancer Patients Cancer | N/A | 2023-01-01 |
| Completed | Preoperative Survey Cognitive Impairment | — | 2022-12-15 |
| Recruiting | Comparing SBRT to CRT in Patients With Spinal Metastases Spinal Metastases | — | 2022-12-12 |
| Unknown | Fenfluramine for Adult Dravet Patients Dravet Syndrome, Dravet Syndrome, Intractable | Phase 3 | 2022-12-10 |
| Recruiting | Kadcyla And Neratinib for Interception of HER2+ Breast Cancer With Molecular Residual Disease Breast Cancer, HER2-positive Breast Cancer | Phase 2 | 2022-12-06 |
| Completed | TorEx Lung Perfusion System Lung Transplant, Ex Vivo Lung Perfusion | N/A | 2022-12-06 |
| Completed | Rehabilitation for People With Advanced Cancer Advanced Breast Cancer, Advanced Colorectal Cancer, Cancer Rehabilitation | N/A | 2022-12-02 |
| Completed | Feasibility of a Virtual Smoking Cessation Program Smoking, Smoking Cessation, Smoking Reduction | N/A | 2022-12-01 |
| Completed | Pilot Open Label Use of the Hi-OXSR for the Treatment of Post COVID-19 Cognitive Dysfunction Post COVID-19 Condition | Phase 1 | 2022-11-29 |
| Recruiting | Patient Reported Outcomes/Metrics Program Trial Metastatic Cancer, Palliative | — | 2022-11-24 |
| Unknown | Comparison of Devices for Atrial Septal Defects Closure: A Pilot Study Atrial Septal Defect | N/A | 2022-11-23 |
| Completed | Improving Pain Disability With the Use of Oral Cannabinoids Chronic Pain, Opioid Use, Cannabis | N/A | 2022-11-22 |
| Active Not Recruiting | A Virtual Reality at Home Intervention for People Living With Dementia Dementia | N/A | 2022-11-17 |
| Enrolling By Invitation | Reference Values for Videofluoroscopic Measures of Swallowing Dysphagia, Oropharyngeal | N/A | 2022-11-15 |
| Unknown | Testing of a New Computer Screen for Patients With Persistent Concussion Symptoms (PCS). Post-Concussion Symptoms | N/A | 2022-11-07 |
| Completed | Prehab for Adult Spinal Deformity Surgery Spinal Deformity | N/A | 2022-11-03 |
| Unknown | Characterization of Bleeding Disorders in EDS Ehlers-Danlos Syndrome, EDS, Classical Ehlers-Danlos Syndrome | — | 2022-11-01 |
| Unknown | Ultrastructural Collagen Markers in Ehlers Danlos Syndromes Ehlers-Danlos Syndrome, Classical Ehlers-Danlos Syndrome, Hypermobile EDS (hEDS) | — | 2022-10-31 |
| Unknown | Paresthesia-free Peripheral Nerve Field Stimulation for Trigeminal Neuralgia (FreeST Trial) Trigeminal Neuralgia, Facial Pain | Phase 1 / Phase 2 | 2022-10-28 |
| Enrolling By Invitation | Semaglutide vs Sitagliptin Liver Transplant; Complications, Diabetes Mellitus, NASH - Nonalcoholic Steatohepatitis | Phase 4 | 2022-10-26 |
| Unknown | Evaluation of Nurse-led Integrated Care of Complex Patients Facilitated By Telemonitoring: The SMaRT Study Heart Failure，Congestive, Mental Health (Depression), Diabetes Mellitus | N/A | 2022-10-17 |
| Recruiting | Activity-Based Therapy and Transcutaneous Spinal Cord Stimulation After Spinal Cord Injury (ABT-TCSCS) Spinal Cord Injuries, Spinal Cord Injury Cervical | N/A | 2022-10-07 |
| Unknown | Tele-BARICARE to Manage COVID-19-Related Distress Obesity, Bariatric Surgery Candidate, Mental Health Disorder | N/A | 2022-10-06 |
| Unknown | My Cardiac Recovery (MyCaRe): A Pilot RCT. Postoperative; Dysfunction Following Cardiac Surgery | N/A | 2022-10-01 |
| Recruiting | Targeted Deprescribing in Patients on Hemodialysis End Stage Renal Disease on Dialysis (Diagnosis) | — | 2022-10-01 |
| Enrolling By Invitation | Combined Bariatric Surgery and Pancreas After Kidney Transplantation for Type II Diabetics Diabetes Mellitus, Type 2, Overweight | N/A | 2022-09-23 |
| Active Not Recruiting | Circulating Tumor DNA Collection From Patients With High Grade Gliomas High Grade Glioma | — | 2022-09-02 |
| Not Yet Recruiting | HPV-SAVE_Merck_Sub-Study for Preventing Recurrence of HSIL Anal Intraepithelial Neoplasia, Anal Cancer, Human Papilloma Virus | Phase 2 | 2022-09-01 |
| Recruiting | Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvo Prostate Cancer | N/A | 2022-08-23 |
| Recruiting | Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI (OPTIMISE SCI Trial) Spinal Cord Injuries, Spine Disease | N/A | 2022-08-15 |
| Unknown | Thrombin in Cardiac Surgery Thrombin, Hemostatic Disorder, Surgical Blood Loss | — | 2022-08-10 |
| Completed | PRehab tO PreparE Living Liver Donors for Enhanced Recovery Living Donor Liver Transplantation | N/A | 2022-08-04 |
| Unknown | Health Technology to Improve Exercise in axSpA Axial Spondyloarthritis | N/A | 2022-07-21 |
| Recruiting | Clinical Outcomes of Pregnant Individuals With Epilepsy - Prospective Study Epilepsy | — | 2022-07-20 |
| Recruiting | Non-Invasive Artificial Intelligence-Based Platform MonIToring Program (NIP IT!) Breast Cancer, Melanoma, Gastrointestinal Neuroendocrine Tumor | — | 2022-07-20 |
| Completed | Prediction of Muscle Responsiveness to FES Therapy Spinal Cord Injury Cervical | N/A | 2022-07-20 |
| Recruiting | Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer Prostate Cancer | N/A | 2022-07-18 |
| Unknown | Diabetic Foot Care and Limb Preservation Pathway: Developmental Evaluation Study Diabetic Foot, Lower Limb Wound, Diabetes | — | 2022-07-15 |
| Recruiting | A2 to O Lung Transplants Lung Transplant, ABO Incompatibility | N/A | 2022-07-14 |
| Recruiting | Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O) Breast Cancer, Colorectal Cancer, Pancreas Cancer | — | 2022-06-23 |
| Terminated | THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS) Sickle Cell Disease, Central Venous Catheter Thrombosis, Venous Thromboembolism | Phase 3 | 2022-06-07 |
| Recruiting | Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches Chronic Daily Headache | Phase 3 | 2022-06-01 |
| Completed | Luspatercept in Metastatic AGCT of the Ovary Adult Granulosa Cell Tumor of the Ovary | N/A | 2022-05-30 |
| Completed | Erdafitinib in Metastatic Steroid-cell Ovarian Cancer Ovarian Cancer, Steroid Cell Tumor, Malignant | N/A | 2022-05-30 |
| Completed | A Web-based Peer Navigation Program for Men With Prostate Cancer Prostate Cancer | N/A | 2022-05-13 |
| Completed | VRx@Home: Study to Evaluate VR-therapy for PwD Living at Home Dementia | N/A | 2022-05-10 |
| Completed | ......SMARTEST Trial...... Mesothelioma, Malignant | Phase 2 | 2022-05-03 |
| Unknown | Vision-based Assessment of Joint Extensibility in Ehlers Danlos Syndrome Ehlers-Danlos Syndrome | — | 2022-04-26 |
| Completed | Integrated Pulmonary Index for Nurse-administered Procedural Sedation Conscious Sedation, Nursing, Anaesthesia | N/A | 2022-04-22 |
| Unknown | HCV Treatment Initiation During Acute Psychiatric Admission Hepatitis C | Phase 4 | 2022-04-19 |
| Unknown | Pharmacist-led Hepatitis C Management Hepatitis C Virus Infection | Phase 4 | 2022-04-13 |
| Completed | Emotion and Symptom-focused Engagement for Caregivers (EASE-CG) Pilot Study Leukemia, Acute | N/A | 2022-04-12 |
| Completed | The Harmonized Interventions to Maintain Health Via Appropriate Risk Factor Modification and Lifestyle Changes Heart Failure, Cardiotoxicity, Cancer | N/A | 2022-04-01 |
| Recruiting | Using ctDNA to Determine Therapies for Lung Cancer Non Small Cell Lung Cancer, Complete Surgical Resection, Circulating Tumor DNA | Phase 2 | 2022-03-28 |
| Completed | Timing of Post-prostatectomy PSMA Imaging Prostate Cancer, Prostatectomy | Phase 2 | 2022-03-22 |
| Active Not Recruiting | Impact of Cultural and Linguistic Backgrounds on Patient Care and Experience of Women With Gynecologic Maligna Gynecologic Cancer | — | 2022-03-15 |
| Completed | Effortful Swallow Maneuver for Swallowing Impairment in People With Parkinson Disease Parkinson Disease, Dysphagia | N/A | 2022-03-09 |
| Completed | Cognitive and Physical Training in Patients With Chronic Obstructive Pulmonary Disease Patients Pulmonary Disease, Chronic Obstructive | N/A | 2022-03-01 |
| Withdrawn | Mapping 3D Bladder Bladder Cancer | — | 2022-03-01 |
| Recruiting | R-RPLND as First-line Treatment for Clinical Stage IIA/B Testicular Seminoma Lymphadenopathy Retroperitoneal, Stage II Testicular Seminoma | N/A | 2022-02-23 |
| Completed | Contactless Vital Signs Measurement Blood Pressure, Heart Rate, Respiratory Rate, Heart Rate Variability, Stress Index, Vital Signs Monitoring, Vital Signs Monitoring | — | 2022-02-11 |
| Completed | Prehabilitation to Improve Cancer Surgery Outcomes in AYA Patients With Extremity Sarcomas Sarcoma,Soft Tissue, Osteosarcoma | N/A | 2022-02-02 |
| Enrolling By Invitation | Project Open - Use of Administrative Health Data to Increase Diabetic Retinopathy Screening Diabetes, Diabetic Retinopathy | — | 2022-02-01 |
| Recruiting | Visualization of Neural Targets With 3T MRI Neuro-Degenerative Disease | — | 2022-01-29 |
| Terminated | Study of Nivolumab-Ipilimumab and cfDNA in Lung Cancer Non Small Cell Lung Cancer | Phase 2 | 2022-01-24 |
| Completed | IMPROV-ing The Impostor Phenomenon Impostor Phenomenon | N/A | 2022-01-17 |
| Unknown | MIRA Clinical Learning Environment (MIRACLE): Lung Lung Cancer | — | 2022-01-01 |
| Recruiting | Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility Study Anesthesia, Brain Cancer, Survival | N/A | 2022-01-01 |
| Unknown | Assessment of Oxygen Delivery as an Early Predictor of Postoperative Pulmonary Complications During One-lung P Postoperative Pulmonary Complications | N/A | 2022-01-01 |
| Active Not Recruiting | A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to Graft Vs Host Disease | Phase 2 | 2021-12-22 |
| Recruiting | Study of Pembrolizumab With Bendamustine in Hodgkin Lymphoma Classical Hodgkin Lymphoma, Relapsed Cancer, Refractory Cancer | Phase 2 | 2021-12-20 |
| Recruiting | StereoTactic Ablative RadioTherapy of Cardiac Arrhythmias Cardiac Arrhythmia | N/A | 2021-12-14 |
| Recruiting | Biofeedback Training for Hemianopia Hemianopia, Brain Injuries | N/A | 2021-12-08 |
| Unknown | Pembrolizumab in Small Cell Carcinoma of Ovary - Hypercalcemic Type Patient Small Cell Carcinoma, Hypercalcaemic Type, Ovarian Cancer | N/A | 2021-12-06 |
| Recruiting | Biofeedback for Hemianopia Vision Rehabilitation Hemianopsia, Homonymous, Brain Injury, Stroke | N/A | 2021-12-01 |
| Withdrawn | LIpitor and biGuanide to Androgen Delay Trial Prostate Cancer | Phase 2 | 2021-12-01 |
| Unknown | Biologic Tapering Study of TNF Inhibitors in Axial Spondyloarthritis Axial Spondyloarthritis | Phase 4 | 2021-12-01 |
| Recruiting | Evaluating the Effectiveness of the Nurse Ned Clinic Prostate Cancer | N/A | 2021-11-15 |
| Recruiting | Hypopharynx ICG to Reduce the Fistula Rate in Patients Undergoing Salvage Laryngectomy Surgery Site Fistula | Phase 2 | 2021-11-11 |
| Active Not Recruiting | COVID-19 Burnout Study Stress | N/A | 2021-11-01 |
| Terminated | Functional Electrical Stimulation for Facial Muscles Facial Nerve Paresis | N/A | 2021-11-01 |
| Completed | ODYSSEE-vCHAT Pilot Trial for Heart Failure Heart Failure | N/A | 2021-10-25 |
| Unknown | RESTORE in Patients Who Had COVID-19 and Close Others Mental Health, PTSD, Anxiety | N/A | 2021-10-22 |
| Recruiting | Digital Technology for Sleep and Homelessness Sleep Apnea, Sleep Disorder, Sleep Deprivation | N/A | 2021-10-20 |
| Active Not Recruiting | Phase II RCT of an Internet-adaptation of Managing Cancer and Living Meaningfully (iCALM) Advanced Cancer | N/A | 2021-10-13 |
| Unknown | Effect of Diet Induced Ketosis on LDL Turnover Rates Ketosis, Metabolic | N/A | 2021-10-12 |
| Unknown | Brain Insulin Resistance in Mood Disorders Major Depressive Disorder, Bipolar Disorder, Anhedonia | Phase 1 / Phase 2 | 2021-10-06 |
| Completed | Semaglutide for the Treatment of Cognitive Dysfunction in Major Depressive Disorder Major Depressive Disorder | Phase 2 | 2021-10-06 |
| Recruiting | Brain Imaging Biomarkers in Patients With Brain Metastasis Brain Metastases, Adult | Phase 2 | 2021-10-05 |
| Unknown | Patient Perspectives on Advance Care Planning Discussions Prior to Cardiac Surgery Cardiac Surgery | — | 2021-10-01 |
| Completed | Immune Response to COVID-19 Vaccine in Immunotherapy (IO) and Non-IO Treated Cancer Patients COVID-19, Cancer | — | 2021-09-28 |
| Enrolling By Invitation | International CR Registry Acute Coronary Syndrome, Heart Failure, Coronary Artery Disease | — | 2021-09-27 |
| Completed | Losing Balance to Prevent Falls After Spinal Cord Injury (RBT+FES) Spinal Cord Injuries | N/A | 2021-09-27 |
| Completed | Photovoice for Spinal Cord Injury to Prevent Falls Spinal Cord Injuries | N/A | 2021-09-27 |
| Unknown | Dual Perfusion Imaging for Characterizing Vascular Architecture of Brain Lesions Brain Tumor, Brain Metastases | N/A | 2021-09-24 |
| Recruiting | Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN) Post-mastectomy Pain Syndrome, Breast Cancer, Pain, Postoperative | Phase 3 | 2021-09-22 |
| Unknown | ODYSSEE-vCHAT Mental Health Program for Heart Failure and Kidney Disease Patients Chronic Heart Failure, Chronic Kidney Diseases | — | 2021-09-14 |
| Completed | Study of Lymphatic Drainage Mapping in Oropharyngeal Cancers Oropharynx Cancer | N/A | 2021-09-13 |
| Completed | Cancer Rehab Program for Allogenic Bone and Marrow Transplant Patients - CaRE-4-alloBMT Allogeneic Disease, Hematologic Cancer, Cancer Rehabilitation | N/A | 2021-09-08 |
| Unknown | Adverse Childhood Experiences in Patients With Coronary Artery Disease Pilot Adverse Childhood Experiences, Coronary Artery Disease | N/A | 2021-09-01 |
| Unknown | TOGETHER - Toronto: Trial to Evaluate the Effect of Peginterferon Lambda for the Treatment of COVID-19 Sars-CoV2, Covid19 | Phase 3 | 2021-08-27 |
| Completed | Feasibility of a Home Exercise Program to Manage Post-transplant Metabolic Syndrome Metabolic Syndrome | N/A | 2021-08-19 |
| Completed | Dyspnea in Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorder Hypermobile EDS (hEDS), Hypermobility Syndrome | N/A | 2021-08-16 |
| Active Not Recruiting | Myocardial Injury and Outcomes Following COVID-19 Vaccination (MYOVAX Study) Myocardial Injury, Myocarditis, COVID-19 Vaccination | N/A | 2021-08-05 |
| Unknown | Deoxyhemoglobin Concentration Changes and Cerebral Perfusion Imaging Stenosis, Carotid, Stroke, Neurovascular Disorder | N/A | 2021-08-01 |
| Active Not Recruiting | Erector Spinae Plane (ESP) Block Volunteer Study Pain Management | N/A | 2021-07-28 |
| Completed | Post-operative Functional Disability in Unrecognized Cognitive Impairment (POF) Study Cognitive Impairment (CI) | — | 2021-07-23 |
| Unknown | NIVIA-Hemodynamics Cardiogenic Shock, Heart Failure, Shock | — | 2021-07-17 |
| Withdrawn | Maintenance Treatment With Bevacizumab and Atezolizumab for Ovarian Cancer Ovarian Endometrioid Tumor, Fallopian Tube Cancer, Primary Peritoneal Cancer | Phase 2 | 2021-07-16 |
| Completed | Efficacy, Mechanisms and Safety of SGLT2 Inhibitors in Kidney Transplant Recipients Kidney Transplant Recipients, Post-transplant Diabetes Mellitus, Type 2 Diabetes | Phase 3 | 2021-07-15 |
| Unknown | The Relationship Between Cannabis Use, Biomarkers, Tissue Cannabinoid Levels and Clinical Outcomes in Patients Osteo Arthritis Knee | — | 2021-07-13 |
| Completed | Treatment of Bipolar Depression With Pentoxifylline Bipolar Depression | EARLY_Phase 1 | 2021-07-12 |
| Recruiting | Using ctDNA to Detect Minimal Residual Disease After Lung Cancer Resection Non Small Cell Lung Cancer | — | 2021-07-06 |
| Recruiting | MCID and PASS for Acute Pain and Quality of Recovery After Orthopedic Surgery Pain Management | — | 2021-06-21 |
| Recruiting | Fabry Cardiomyopathy: Identification of Early Myocardial Structural and Tissue Abnormalities Using Multiparame Fabry Disease | N/A | 2021-06-15 |
| Active Not Recruiting | BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial Brain Neoplasms, Liquid Biopsy | N/A | 2021-06-10 |
| Completed | Implementing Peri-operative Mobile Application for Contactless Vital Signs Blood Pressure, Heart Rate, Breathing Rate and Oxygen Level | — | 2021-06-04 |
| Active Not Recruiting | An Exploratory Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma and Non-Small Cell Lung Cance Hepatocellular Carcinoma, Non-small Cell Lung Cancer Metastatic, Liver Metastases | Phase 2 | 2021-06-04 |
| Recruiting | PET/MR Pre- and Post Radiotherapy for Cardiopulmonary Dysfunction Evaluation Pulmonary Hypertension | N/A | 2021-06-01 |
| Completed | Third Dose of Moderna COVID-19 Vaccine in Transplant Recipients Vaccine Response Impaired, Immune Suppression, Covid19 | Phase 4 | 2021-05-25 |
| Active Not Recruiting | Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity Low Intensity Focussed Ultrasound | EARLY_Phase 1 | 2021-05-25 |
| Active Not Recruiting | FAZA PET/MRI Pancreas Pancreatic Adenocarcinoma Non-resectable, Locally Advanced Pancreatic Adenocarcinoma, Unresectable Pancreatic Cancer | N/A | 2021-05-18 |
| Recruiting | Bariatric Surgery for Fertility-Sparing Treatment of Atypical Hyperplasia and Grade 1 Cancer of the Endometriu Endometrial Cancer, Atypical Hyperplasia, Bariatric Surgery Candidate | N/A | 2021-05-14 |
| Unknown | SafeTy and Efficacy of Preventative CoVID Vaccines COVID-19 Virus Infection, Vaccine Response | — | 2021-05-06 |
| Terminated | Can INSTI-associated Weight Gain be Halted or Reversed With a Switch to Doravirine/Lamivudine/Tenofovir DF? Hiv, Weight Gain | Phase 4 | 2021-04-26 |
| Completed | Effect of Soundscape on People With Dementia. Dementia, Behavioural and Psychiatric Symptoms of Dementia | N/A | 2021-04-21 |
| Unknown | Factor In the Initial Resuscitation of Severe Trauma 2 Patients Traumatic Hemorrhage, Coagulopathy, Massive Hemorrhage | Phase 4 | 2021-04-01 |
| Completed | A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients Soft Tissue Sarcoma, Malignant Peripheral Nerve Sheath Tumor (MPNST), Leiomyosarcoma | Phase 1 | 2021-03-29 |
| Completed | Further Development and Initial Testing of RESTORE in Frontline Workers Mental Health, PTSD, Anxiety | N/A | 2021-03-23 |
| Completed | Decidual Stromal Cells to Treat Graft-vs-Host Disease After Stem Cell Transplant for Myelodysplastic Syndrome/ Myelodysplastic/Myeloproliferative Neoplasm, Steroid Refractory GVHD, Allogeneic Hematopoietic Cell Transplant | Phase 2 | 2021-03-11 |
| Active Not Recruiting | Modulating Cerebellar Activity With Low-intensity Focused Ultrasound Stimulation for Primary Orthostatic Tremo Orthostatic Tremor | N/A | 2021-03-08 |
| Unknown | Thrombin Generation in Liver Transplant Surgery Liver Transplantation, Thrombin, Hemostasis, Surgical | — | 2021-03-08 |
| Active Not Recruiting | Dual Tracer (68Ga-DOTATATE and 18F-FDG) PET Imaging in G2 & G3 Gastroenteropancreatic Neuroendocrine Tumors Neuroendocrine Tumors | N/A | 2021-03-04 |
| Active Not Recruiting | Implementation and Evaluation of a Stepped-Care Mental Health Treatment Program for Patients With Chronic Pain Chronic Pain | — | 2021-03-01 |
| Recruiting | Acalabrutinib With R-CHOP in Previously Untreated Mantle Cell Lymphoma Mantle Cell Lymphoma | Phase 2 | 2021-03-01 |
| Unknown | Post Concussion Symptoms Risk Stratification Tool Post-Concussion Syndrome | N/A | 2021-02-17 |
| Unknown | DOTATATE PETMRI AAA Study Abdominal Aortic Aneurysm | N/A | 2021-02-15 |
| Recruiting | Neoadjuvant Upper Tract Invasive Cancer Trial (NAUTICAL) Bladder Cancer, Bladder Urothelial Carcinoma | Phase 3 | 2021-02-08 |
| Active Not Recruiting | Active Surveillance and Surgery Outcomes in Low Risk Papillary Thyroid Cancer Papillary Thyroid Cancer, Papillary Thyroid Carcinoma, Papillary Microcarcinoma of the Thyroid | — | 2021-02-03 |
| Active Not Recruiting | Accelerating Lung Cancer Diagnosis Through Liquid Biopsy Non-small Cell Lung Cancer | — | 2021-01-14 |
| Unknown | Virtual Assistant for COVID-19 PPE COVID-19 | N/A | 2021-01-02 |
| Withdrawn | A Multi-Cancer, Multi-State, Platform Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Pancreatic Ad Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer, Squamous Cell Carcinoma of Head and Neck | Phase 2 | 2021-01-01 |
| Unknown | Fluorescence Image-Guided Healing Trial Diabetic Foot Ulcer | Phase 4 | 2021-01-01 |
| Completed | Swallowing Impairment After COVID-19 Infection Covid19 | — | 2021-01-01 |
| Withdrawn | Post-Concussion Aerobic Exercise Concussion, Mild, Mild Traumatic Brain Injury | N/A | 2021-01-01 |
| Withdrawn | A Phase 2 Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Multi-Cancer Populations With Correlation Non Small Cell Lung Cancer, Renal Cell Carcinoma | Phase 2 | 2021-01-01 |
| Unknown | Platelet Rich Plasma Eye Drops for Treatment of Ocular Surface Disease Ocular Surface Disease, Dry Eye Syndromes | Phase 4 | 2021-01-01 |
| Unknown | Enhanced Hood PPE to Minimize COVID-19 Transmission to Front-line Health Care Workers Covid19 | N/A | 2020-12-07 |
| Unknown | Cannabis Oil for Pain in Parkinson's Disease Parkinson Disease | Phase 2 | 2020-12-01 |
| Unknown | Apple-CPET Ted Rogers Understanding Exacerbations of Heart Failure Heart Failure, Heart Failure, Systolic, Heart Failure, Diastolic | — | 2020-12-01 |
| Recruiting | LANDscape MApping of Epitopes and T Cell Receptors for Selected Cancers Solid Tumor | — | 2020-11-30 |
| Terminated | A Study of Various Treatments in Serous or p53 Abnormal Endometrial Cancer Endometrial Carcinoma, P53 Mutation, Serous Carcinoma | Phase 2 / Phase 3 | 2020-11-17 |
| Completed | The Ketamine for Acute Postoperative Analgesia (KAPA) Trial Postoperative Pain | Phase 3 | 2020-11-17 |
| Unknown | Atherectomy and Drug Coated Balloon for the Treatment of Arterio-Venous Graft Stenosis Dysfunctional Arterial-venous Grafts | N/A | 2020-11-12 |
| Terminated | Study of Enasidenib and Venetoclax in IDH2-Mutated Blood Cancers Acute Myeloid Leukemia, Relapsed Cancer, Refractory Cancer | Phase 1 / Phase 2 | 2020-11-05 |
| Completed | At Home Monitoring for Patients With Covid19 Coronavirus | N/A | 2020-11-01 |
| Completed | Study of Circulating Tumor DNA (ctDNA) Kinetics in Immuno-oncology (IO-KIN) Head and Neck Cancer, Advanced Cancer, Metastatic Cancer | — | 2020-10-19 |
| Active Not Recruiting | Real-time Detection of ctDNA and/or HPV DNA in High-risk Locally-advanced Head and Neck Squamous Cell Carcinom Cancer, Head and Neck Squamous Cell Carcinoma, Head and Neck Cancer | — | 2020-10-15 |
| Completed | Pancreatic Adenocarcinoma Signature Stratification for Treatment Pancreatic Cancer Metastatic, Pancreatic Ductal Adenocarcinoma, Advanced Pancreatic Cancer | Phase 2 | 2020-10-14 |
| Recruiting | Talazoparib and Thoracic RT for ES-SCLC Lung Cancer, Small-Cell Lung Cancer | Phase 1 | 2020-10-05 |
| Completed | An Impact Assessment of a Culturally Tailored Online Psychosocial Program for Chinese Immigrant Women With Bre Breast Cancer | N/A | 2020-10-01 |
| Recruiting | Partial Neuromuscular Blockade in Acute Hypoxemic Respiratory Failure Respiratory Insufficiency, Neuromuscular Blockade, Mechanical Ventilation | N/A | 2020-10-01 |
| Completed | Development and Validation of an Online Independent Training Program for TOR-BSST© Dysphagia Screeners Dysphagia, Stroke | N/A | 2020-10-01 |
| Active Not Recruiting | FLT-PET / MRI Brain Mets Brain Metastases, Radionecrosis | — | 2020-10-01 |
| Completed | Study of Decidual Stromal Cells to Treat COVID-19 Respiratory Failure COVID-19, Acute Respiratory Distress Syndrome | N/A | 2020-09-25 |
| Recruiting | FAZA PETMRI Gastro-Oesophageal Study Metastasized Gastro-Oesophageal Cancer | N/A | 2020-09-15 |
| Completed | High Dose Inhaled Nitric Oxide for COVID-19 (ICU Patients) COVID-19 | Phase 1 | 2020-09-02 |
| Completed | Perfexion Registration Using CBCT Brain Metastases | — | 2020-09-01 |
| Completed | Untreated Sleep Apnea as an Aggravating Factor for Other Secondary Medical Conditions After Spinal Cord Injury Sleep Apnea, Spinal Cord Injuries, Spasticity, Muscle | — | 2020-09-01 |
| Withdrawn | Radiotherapy Versus no Intervention in Adult Patients With Hepatocellular Carcinoma Not Eligible for Transarte Hepatocellular Carcinoma | N/A | 2020-09-01 |
| Recruiting | Inspiratory Work of Breathing Before and After Extubation Lung Transplant; Complications, Ventilator-Induced Lung Injury, Ventilator Associated Pneumonia | — | 2020-09-01 |
| Completed | Subcutaneous Immunoglobulin for Myasthenia Gravis Myasthenia Gravis | Phase 2 | 2020-08-28 |
| Unknown | Testing Efficacy of VR in Medical Education Virtual Reality and Medical Education | N/A | 2020-08-28 |
| Unknown | Immune Resistance Interrogation Study Cancer, Solid Tumor, Metastatic Cancer | — | 2020-08-26 |
| Completed | Planned Semi-Elective Lung Tx Study Lung Transplantation | N/A | 2020-08-26 |
| Active Not Recruiting | GATA6 Expression as a Predictor of Response to Peri-Operative Chemotherapy in Resectable Pancreatic Adenocarci Resectable Pancreatic Cancer | N/A | 2020-08-21 |
| Completed | Evaluation of a Brachytherapy Discharge Education Program to Improve Patient Care Gynecologic Cancer | N/A | 2020-08-19 |
| Unknown | Expert Behaviors USGRA Anesthesia Education | — | 2020-08-15 |
| Active Not Recruiting | The Person-centered Evolution of Radiotherapy Services in Ontario Study Breast Cancer, Quality of Life | N/A | 2020-08-13 |
| Completed | Covid-19 Airway Management Covid-19_airways Management | — | 2020-08-10 |
| Recruiting | Cabozantinib to Treat Recurrent Liver Cancer Post Transplant Hepatocellular Carcinoma, Recurrent Cancer, Liver Transplant | Phase 2 | 2020-08-07 |
| Active Not Recruiting | Study of Stem Cell Transplant vs. Non-Transplant Therapies in High-Risk Myelofibrosis Myelofibrosis, High-Risk Cancer, Bone Marrow Cancer | — | 2020-08-05 |
| Enrolling By Invitation | Ex-Vivo COF Study for Lung Cancer Observation Lung Cancer | — | 2020-08-05 |
| Unknown | The Açaí Berry COVID-19 Anti-Inflammation Trial COVID | Phase 2 | 2020-08-04 |
| Recruiting | Real-World Evidence in Patient-Reported Outcomes for Medical Cannabis (MC-RWE) Pain, Sleep, Anxiety | — | 2020-07-15 |
| Completed | Sleep Health Program for Patients With Chronic Pain Sleep Disordered Breathing, Chronic Pain, Sleep | N/A | 2020-07-09 |
| Active Not Recruiting | Bilateral Essential Tremor Treatment With FUS Essential Tremor | N/A | 2020-07-08 |
| Unknown | Ex-vivo Delivery of Rituximab to Prevent PTLD in EBV Mismatch Lung Transplant Recipients: A Pilot Trial Epstein-Barr Virus Infections, Post-transplant Lymphoproliferative Disorder | Phase 1 / Phase 2 | 2020-07-07 |
| Completed | A Study to Desensitize Allergic Reactions to Treatments for Blood Disorders Multiple Myeloma, Amyloidosis | Phase 2 | 2020-07-03 |
| Unknown | Cardiovascular Disease and Outcomes Among Patients With SARS-CoV-2 Infection (COVID-19) COVID-19 Respiratory Infection | — | 2020-07-01 |
| Unknown | Trials of Ventilation Assisted Substance Elimination Via the Lung - Ethanol (VASEL - Ethanol) Alcohol Intoxication | N/A | 2020-07-01 |
| Completed | Efficacy and Safety of VPM1002 in Reducing SARS-CoV-2 (COVID-19) Infection Rate and Severity SARS-CoV-2 Infection | Phase 3 | 2020-06-24 |
| Active Not Recruiting | The Canadian COVID-19 Prospective Cohort Study Covid19 | — | 2020-06-17 |
| Unknown | Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine Supplementation Thalassemia Major | N/A | 2020-06-01 |
| Withdrawn | Study of Sodium Bicarbonate in Restoring Blocked Catheters Cancer, Central Venous Catheterization | Phase 2 | 2020-06-01 |
| Completed | Medical Safety Huddles - a Multi-site QI Project Patient Safety | N/A | 2020-06-01 |
| Terminated | Study of the Efficacy and Safety of Ruxolitinib to Treat COVID-19 Pneumonia COVID-19, Pneumonia | N/A | 2020-05-21 |
| Completed | Mental Health Outcomes in Healthcare Workers During COVID-19 Mental Health Wellness 1, PTSD, Anxiety | — | 2020-05-14 |
| Completed | Interferon Lambda for Immediate Antiviral Therapy at Diagnosis in COVID-19 Sars-CoV2, Covid-19 | Phase 2 | 2020-05-13 |
| Terminated | Screening of Cancer Patients to Assess Impact of COVID-19 Covid-19, Cancer | — | 2020-05-11 |
| Completed | A Research Platform to Screen Healthcare Workers- Coordinated Approach to Pandemic Trials of COVID-19 Healthcare Worker, Covid19 | — | 2020-04-16 |
| Completed | Enhanced Triage for COVID-19 COVID-19, SARS-CoV 2 | — | 2020-04-01 |
| Not Yet Recruiting | Canadian Adult Congenital Heart Disease Intervention Registry Atrial Septal Defect, Patent Foramen Ovale, Tetralogy of Fallot | — | 2020-04-01 |
| Unknown | Multicenter Validation of a Predictor Model of ACHD Patients and Cardiac Surgery Adult Congenital Heart Disease, Cardiac Surgery | — | 2020-03-10 |
| Unknown | A Longitudinal Quantitative Assessment of the Effectiveness of Metatarsal Pads on Plantar Pressures Forefoot Callus, Podiatry, Foot Dermatoses | N/A | 2020-03-06 |
| Unknown | Breathomics as Predictive Biomarker for Checkpoint Inhibitor Response NSCLC, Melanoma, Kidney Cancer | — | 2020-02-24 |
| Recruiting | Effect of Erector Spinae (ESP) Block on Opioid Reduction and Enhanced Recovery After Posterior Cervical Spine Postoperative, Pain | N/A | 2020-02-17 |
| Recruiting | FIGO 2018 Stage IB2 Cervical Cancer Treated With Neoadjuvant Chemotherapy Followed by Fertility Sparing Surger Cervical Cancer | N/A | 2020-02-11 |
| Completed | Incidence, Risk Factors and Outcomes of Diaphragm Dysfunction After Lung Transplantation Diaphragm Injury, Lung Transplant; Complications, Mechanical, Respiratory Failure | — | 2020-02-10 |
| Unknown | DAPAgliflozin Sodium Water glucosE EffecTs in Patients at High Cardiovascular Risk Cardiovascular Risk Factor | Phase 2 | 2020-02-10 |
| Completed | Fitness Training Using WBEMS Among Individuals With SCI Spinal Cord Injuries | N/A | 2020-02-01 |
| Recruiting | CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS) Cancer, Malignancies Multiple, Malignant Solid Tumor | — | 2020-01-17 |
| Completed | The PET- Retroperitoneal Sarcoma Study Retroperitoneal Sarcoma | N/A | 2020-01-03 |
| Withdrawn | Molecular Profiling of Advanced Biliary Tract Cancers Biliary Tract Cancer | N/A | 2020-01-01 |
| Suspended | Spinal Morphine for Patients With Obstructive Sleep Apnea Obstructive Sleep Apnea | N/A | 2020-01-01 |
| Recruiting | Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors Glioma, Cholangiocarcinoma, Solid Tumor | Phase 2 | 2019-12-31 |
| Completed | Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation Study Major Depressive Disorder | Phase 3 | 2019-12-23 |
| Completed | Evaluating Positron Emission Mammography Imaging of Suspicious Breast Abnormalities Breast Cancer | N/A | 2019-12-17 |
| Enrolling By Invitation | Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma Cholangiocarcinoma, Intrahepatic | N/A | 2019-12-10 |
| Active Not Recruiting | Magnetic Resonance-Guided Adaptive Radiotherapy (MRgART) Using an Integrated Magnetic Resonance Linear Acceler Cancer | — | 2019-12-09 |
| Recruiting | Study of Crizotinib for ROS1 and MET Activated Lung Cancer Non-squamous Non-small-cell Lung Cancer, Stage IV Non-small Cell Lung Cancer, ROS1 Gene Rearrangement | Phase 2 | 2019-12-03 |
| Unknown | The Safety and Feasibility of Transoral Endoscopic Thyroidectomy Vestibular Approach Thyroid Diseases, Surgery | Phase 1 | 2019-12-01 |
| Completed | Survey of the Facial Bacteriome Understanding Skin Health and the Microbiome, Microbial Colonization | — | 2019-11-25 |
| Recruiting | Molecular Characteristics of Gastroesophageal Adenocarcinoma (MOCHA): A Prospective Feasibility Study Esophagogastric Adenocarcinoma | — | 2019-11-14 |
| Withdrawn | Comparison of OpeN VErsus RoboTic Partial Nephrectomy Renal Masses | N/A | 2019-11-01 |
| Suspended | Surgical and Patient Reported Outcomes of Robotic Nipple-Sparing Mastectomy Breast Cancer, Surgery--Complications, Genetic Predisposition to Disease | N/A | 2019-11-01 |
| Completed | Motion of Kids on Radiation Treatment Observational Study | — | 2019-10-29 |
| Completed | Toward a Comprehensive Supportive Care Intervention for Older or Frail Men With mCRPC Metastatic Prostate Cancer | — | 2019-10-25 |
| Completed | IPACK Study in Total Knee Arthroplasty Patients Knee Replacement Arthroplasty | Phase 4 | 2019-10-24 |
| Completed | Nasal High Flow Therapy in Surgical Patients with Unrecognized Obstructive Sleep Apnea Obstructive Sleep Apnea, Sleep Disordered Breathing | N/A | 2019-10-01 |
| Unknown | Does a Theory-Based Intervention to Improve Accountability Reduce Low-Value Preoperative Investigations in Pat Low-value Pre-operative Investigations | N/A | 2019-10-01 |
| Recruiting | Psychosocial, Cognitive, and Behavioral Consequences of Sleep-disordered Breathing After SCI Spinal Cord Injuries, Sleep Apnea | N/A | 2019-09-27 |
| Completed | 3D Printed Mask for GBM and Brain Mets Brain Cancer | N/A | 2019-09-26 |
| Unknown | Factor Replacement in Surgery Bleeding in Cardiac Surgery | Phase 2 | 2019-09-24 |
| Recruiting | Study of Binimetinib in Combination With Pembrolizumab in Advanced Non-Small Cell Lung Cancer Non-small Cell Carcinoma | Phase 1 | 2019-09-20 |
| Completed | Pain Management for Cystoscopy: A Prospective Randomized Study Focused on Understanding the Role of the "Bag S Pain, Procedural | N/A | 2019-09-16 |
| Completed | Chewing and Oral Processing of Solid Food Dysphagia | — | 2019-09-13 |
| Recruiting | The Role of Stereo-tActic BoDy RadIotherApy iN Oligo-Progressive MalignanT Disease Malignancy, Breast Cancer Metastatic, Genito-urinary | N/A | 2019-09-11 |
| Active Not Recruiting | A Feasibility Study Evaluating Surgery for Mesothelioma After Radiation Therapy Using Extensive Pleural Resect Mesothelioma; Lung | N/A | 2019-09-05 |
| Recruiting | Prospective Analysis of Intestinal Microbiome and Autoimmune Panels as Predictors of Toxicity in ImmunOncology Solid Tumor | — | 2019-09-05 |
| Completed | Augmenting Reactive Stepping With FES After SCI Spinal Cord Injuries | N/A | 2019-09-01 |
| Recruiting | FAZA PET/MRI in CLI Patients Pre and Post Revascularization Critical Limb Ischemia | N/A | 2019-08-31 |
| Completed | Carotid PET/MRI With DOTATATE in Patients Post Head and Neck Radiation Therapy Head & Neck Cancer | N/A | 2019-08-22 |
| Terminated | Symptom Screening With Targeted Early Palliative Care (STEP) Versus Usual Care for Patients With Advanced Canc Cancer | N/A | 2019-08-08 |
| Completed | High Flow Nasal Oxygen During Sedation Anesthesia, Cardiac Disease | N/A | 2019-08-07 |
| Completed | Diagnostic Accuracy Study of Indocyanine Green for Parathyroid Perfusion Assessment Thyroid Cancer, Thyroid Goiter, Graves Disease | Phase 4 | 2019-08-06 |
| Terminated | The Impact of Fluid Volume Shifts on Upper Airway Collapse and Obstructive Sleep Apnea in Surgical Patients Obstructive Sleep Apnea | — | 2019-07-22 |
| Unknown | Decreased Empathy and Emotion Recognition in Patients With Neurodegenerative Disease Neuro-Degenerative Disease, Dementia, Caregiver Burnout | N/A | 2019-07-22 |
| Unknown | Comparison of Carbon Dioxide and Saline Flush to Saline Flush in TEVAR and TAVI Procedures to Reduce Cerebral Thoracic Aortic Aneurysm, Aortic Stenosis Symptomatic, Stroke, Complication | Phase 1 | 2019-07-20 |
| Active Not Recruiting | Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma 2 Head and Neck Squamous Cell Carcinoma | N/A | 2019-07-02 |
| Completed | A Wearable and a Self-management Application for Chronic Obstructive Pulmonary Disease (COPD) Patients at Home Pulmonary Disease, Chronic Obstructive | — | 2019-06-29 |
| Terminated | Global CALM Implementation Study Depression | — | 2019-06-17 |
| Completed | Use of Wearables in Hospitalized General Medicine Patients Hospitalizations | N/A | 2019-06-12 |
| Terminated | Self-Management and Activation to Reduce Treatment-Related Toxicities (SMARTCare) Lymphoma, Lung Cancer, Colo-rectal Cancer | N/A | 2019-06-11 |
| Active Not Recruiting | Binimetinib and Encorafenib for the Treatment of Advanced Solid Tumors With Non-V600E BRAF Mutations Solid Tumor | Phase 2 | 2019-06-07 |
| Completed | Identification of Patients Admitted With COPD Exacerbations and Predicting Readmission Risk Using Machine Lear Copd Exacerbation Acute, Readmission, Machine Learning | — | 2019-06-01 |
| Completed | Micro-Ultrasound/Magnetic Resonance Imaging 001 Diagnoses Disease | — | 2019-05-24 |
| Completed | Surgical Patient Knowledge and Safe Use of Opioids Opioid Use | N/A | 2019-05-23 |
| Recruiting | Mechanisms and Outcome-Prognostication for Paresthesia-based and -Free Spinal Cord Stimulation Neuropathic Pain, Chronic Pain | N/A | 2019-05-16 |
| Withdrawn | Early Flu Shots in SOT Influenza, Solid Organ Transplant | — | 2019-05-07 |
| Terminated | Evaluating the Impact of VR-therapy on BPSD and QoL of Individuals With Dementia Admitted to Hospital Dementia, Delirium Superimposed on Dementia | N/A | 2019-05-06 |
| Completed | Renal Cell Carcinoma Microenvironment Discovery Project Renal Cell Carcinoma | — | 2019-05-06 |
| Unknown | Effects of Oral Glucose and Teduglutide on Plasma Lipoproteins Hyperlipidemias | Phase 2 / Phase 3 | 2019-05-01 |
| Withdrawn | Dosing Intervals of Opioid Medication for Chronic Pain Chronic Pain | Phase 4 | 2019-05-01 |
| Recruiting | FDG-PET and Circulating HPV in Patients With Cervical Cancer Treated With Definitive Chemoradiation (II) Cervical Cancer | N/A | 2019-04-23 |
| Active Not Recruiting | Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors Mismatch Repair Proficient Colorectal Cancer, Pancreatic Adenocarcinoma, Leiomyosarcoma | Phase 2 | 2019-04-08 |
| Completed | Yoga for Persistent Pain Related to Oncology Surgery Persistent Postoperative Pain | N/A | 2019-04-01 |
| Terminated | Tongue Pressure Resistance Training for Swallowing Impairment Post-Stroke Stroke, Dysphagia | N/A | 2019-04-01 |
| Completed | 18F-DCFPyL PET/CT in High-grade Epithelial Ovarian Cancer (PET HOC) Stage III Ovarian Cancer, Stage IV Ovarian Cancer | N/A | 2019-04-01 |
| Recruiting | Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant Diaphragm Injury, Respiratory Failure, Mechanical Ventilation Complication | — | 2019-04-01 |
| Unknown | PRG With and Without Gastropexy Gastrostomy, Gastrostomy Complications | N/A | 2019-04-01 |
| Unknown | Use of Tetrasodium EDTA Catheter Lock Solution for Patients on HTPN Catheter Complications | N/A | 2019-04-01 |
| Completed | 68Ga-DOTATATE PET for Management of Neuroendocrine Tumors Neuroendocrine Tumors | N/A | 2019-03-28 |
| Unknown | Repetitive Transcranial Magnetic Stimulation Trajectory of Outcomes Study Depressive Disorder | N/A | 2019-03-18 |
| Unknown | Therapy With High-flow Oxygen by Nasal Cannula vs Noninvasive Ventilation in Patients With Acute Hypoxemic Res Hypoxemia | N/A | 2019-03-15 |