NCT05358340

Dual Perfusion Imaging for Characterizing Vascular Architecture of Brain Lesions

Combined Spin- and Gradient-Echo Perfusion Weighted Imaging for Characterizing Vascular Architecture of Brain Lesions

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University Health Network, Toronto · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objectives of the study are (1) to evaluate the feasibility of using a combined spin- and gradient- echo (SAGE) sequence in dynamic susceptibility contrast magnetic resonance imaging (DSC MRI) and (2) to determine quantitative estimates of vessel density and size to differentiate between areas of radiation necrosis and tumor recurrence.

Conditions

• Brain Tumor
• Brain Metastases

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Dynamic susceptibility contrast magnetic resonance imaging (DSC MRI)	A dye, known as a contrast agent, will be injected through a needle that is inserted into a vein in the arm or hand. Subsequent magnetic resonance imaging will follow.

Timeline

• Start date: 2021-09-24
• Primary completion: 2024-08-01
• Completion: 2024-08-01
• First posted: 2022-05-03
• Last updated: 2023-05-09

Locations

1 site across 1 country: Canada