NCT06688994

Vitamin D Metabolites as Biomarkers for the Identification of Kidney Injury in Cardiac Surgery

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 46 (actual)
• Sponsor: University Health Network, Toronto · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators will be measuring vitamin D metabolites in blood samples drawn from patients undergoing cardiac surgery to determine the correlation with renal function as assessed by serum creatinine. The investigators will include 20 patients in each of the following 3 groups based on serum creatinine measured within 28-days of surgery: 1) normal kidney function (eGFR \> 60 mL/min, n=20), 2) moderate impaired kidney function, eGFR between 30 and 60 mL/min (n=20) and 3) severe kidney dysfunction eGFR \< 30 mL/min (n=20).

Conditions

• Acute Kidney Injuries
• Chronic Renal Diseases

Timeline

• Start date: 2024-12-02
• Primary completion: 2026-07-31
• Completion: 2026-12-31
• First posted: 2024-11-14
• Last updated: 2026-02-03

Locations

1 site across 1 country: Canada