NCT05589701

Comparing SBRT to CRT in Patients With Spinal Metastases

Prospective Registry Trail COMparing Stereotactic Body Radiotherpy (SBRT) to Conventional PAlliative RadioTherapy (CRT) in Patients With Spinal Metastases

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University Health Network, Toronto · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

This is a single institutional registry-based, prospective, observational study to describe radiation oncologists' decision making during evaluation of patients and to compare real-world outcomes of SBRT vs CRT. A registry-based trial involves observing the effect of something without manipulating it.

Detailed description

The purpose of this study is to study the differences between CRT and SBRT. The investigator's are assessing radiation oncologists' decision-making during the evaluation of patients with spinal metastases by requesting radiation oncologists complete a questionnaire. Additionally, the investigator's will compare outcomes, including local progression, pain response and overall survival between SBRT and CRT. By collecting this information, the investigator's will develop an evidence-based algorithm that may be used to support medical decision-making for others with spinal metastases in the future.

Conditions

• Spinal Metastases

Interventions

Type	Name	Description
RADIATION	Radiotherapy	Standard of care radiotherapy administered as per institutional guidelines.

Timeline

• Start date: 2022-12-12
• Primary completion: 2027-12-01
• Completion: 2027-12-01
• First posted: 2022-10-21
• Last updated: 2026-03-05

Locations

1 site across 1 country: Canada