Trials / Recruiting
RecruitingNCT06831032
Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response
A Phase I, Prospective, Single-Arm Feasibility Study: Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response (EASY)
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 26 (estimated)
- Sponsor
- University Health Network, Toronto · Academic / Other
- Sex
- Male
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This prospective, single-arm feasibility study will include patients with prostate cancer that have controlled local disease diagnosed with oligorecurrent para-aortic nodal disease and/or common iliac nodal disease detected by PSMA PET or conventional CT/MRI imaging, and these patients will undergo CT-guided online adaptive SBRT to the tumor and elective SBRT to adjacent at-risk nodal regions.
Conditions
- Prostate Adenocarcinoma
- Iliac Nodal Disease
- Para-aortic Lymph Node Metastasis
- Para-aortic Nodal Disease
- Oligorecurrence
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | Adaptive radiotherapy using SBRT | Adaptive External beam radiotherapy using SBRT 30-40Gy to the tumor nodal GTV volume(s) plus 25 Gy in 5 fractions ENI to PA nodes (+ common iliac nodes) |
Timeline
- Start date
- 2026-07-07
- Primary completion
- 2029-07-07
- Completion
- 2029-07-07
- First posted
- 2025-02-17
- Last updated
- 2026-03-23
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT06831032. Inclusion in this directory is not an endorsement.