NCT04371172

Impact of TAVI on Cognition, Mood and Health-related Quality of Life

The Impact of Transcatheter Aortic Valve Implantation on Cognition, Mood and Health-related Quality of Life - an Explorative Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 128 (estimated)
• Sponsor: Medical University of Graz · Academic / Other
• Sex: All
• Age: 19 Years – 90 Years
• Healthy volunteers: Accepted

Summary

In the proposed study, patients with and without embolic protection devices during Transcatheter Aortic Valve Implantation will be repeatedly examined with a comprehensive psychiatric and cognitive test battery over a post-interventional period of 6 months after TAVI, with regard to the effects on mood, cognitive Performance and health-related Quality of life.

Detailed description

The percutaneous aortic valve replacement (TAVI, Transcatheter Aortic Valve Implantation) enables the implantation of a new biological aortic valve at the beating heart. The procedure is performed under local anaesthesia and is a gold standard in the therapy of aortic stenosis, especially in patients with a too high health risk for cardiovascular surgery. In the proposed study, patients with and without embolic protection devices during TAVI will be repeatedly examined with a comprehensive psychiatric and cognitive test battery over a post-interventional period of 6 months after TAVI, with regard to the effects on mood, cognitive Performance and health-related quality of life.

Conditions

• Cognitive Impairment

Interventions

Type	Name	Description
OTHER	cognitive research battery, MRI, laboratory values	cognitive research battery, MRI, laboratory values

Timeline

• Start date: 2023-02-20
• Primary completion: 2025-05-29
• Completion: 2025-05-29
• First posted: 2020-05-01
• Last updated: 2023-01-11

Locations

1 site across 1 country: Austria