NCT06182995

Anticipating Decline and Providing Therapy

Anticipating Decline and Providing Therapy (ADAPT): Post-ICU Cognitive Screening Pilot and Feasibility Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 109 (actual)
• Sponsor: Wake Forest University Health Sciences · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

This pilot feasibility study will be a randomized control trial of usual care following Intensive Care Unit (ICU) discharge compared to the Anticipating Decline and Providing Therapy (ADAPT) screening and support intervention. The trial aims to enroll 120 older adults (age 60 or older).

Detailed description

Anticipating Decline and Providing Therapy (ADAPT) is a program designed to support the implementation of a routine post-ICU cognitive impairment screening and support intervention. The program includes a routine validated cognitive screen for high-risk older adults at 6 weeks and 6 months post-ICU discharge. Patients with a screening assessment that may be consistent with cognitive impairment or dementia will receive additional resources including a specialized care plan developed by the Sticht Center for Healthy Aging and Alzheimer's Prevention. The specialized care plan is adapted from a health system-based dementia care intervention and designed to support post-ICU cognitive concerns. It was adapted with input from geriatrics, intensive care, and outpatient primary care clinicians. Also conducted are semi-structured interviews with 22 older adult ICU survivors and 6 primary care physicians to elicit preferences and the intervention was further adapted based on these results.

Conditions

• Cognitive Impairment
• Dementia
• Post ICU Syndrome
• Critical Illness
• Cognitive Impairment, Mild

Interventions

Type	Name	Description
BEHAVIORAL	Usual Care post-Intensive Care Unit (ICU)	routine clinic visits
BEHAVIORAL	Anticipating Decline and Providing Therapy (ADAPT)	routine validated cognitive screen for high-risk older adults at 6 weeks and 6 months post-ICU discharge

Timeline

• Start date: 2024-03-08
• Primary completion: 2026-03-01
• Completion: 2026-03-01
• First posted: 2023-12-27
• Last updated: 2026-04-01

Locations

1 site across 1 country: United States