| Not Yet Recruiting | Cholinergic Enhancement of Theta NCT07228338 | University of Texas Southwestern Medical Center | EARLY_Phase 1 |
| Enrolling By Invitation | Low-intensity Hippocampal Transcranial Ultrasound Stimulation for Managing Cognitive and Sleep Dysfunction in NCT07298876 | Chinese University of Hong Kong | N/A |
| Recruiting | Cognitive Assessment And Post-Operative Complications After Surgery: Linking Anaesthesia And Risk NCT07470216 | University of Edinburgh | — |
| Recruiting | Depressive Symptoms, Cognitive Impairment, and Outcomes in Hospitalized Chronic Heart Failure Patients NCT07284446 | Lithuanian University of Health Sciences | — |
| Enrolling By Invitation | Tau PET Outcomes With Anti-amyloid Immunotherapies NCT06723015 | Mayo Clinic | Phase 2 |
| Recruiting | Effects of Personalized Digital Reminiscence Therapy on Patients With Neurocognitive Disorders NCT07237009 | KompanionCare SAS | — |
| Not Yet Recruiting | Dance Intervention to Improve Executive Function and Physical Performance in Older Adults With Cognitive Impai NCT07105800 | Taipei Medical University Shuang Ho Hospital | N/A |
| Recruiting | Repurposing Siponimod for Alzheimer's Disease NCT06639282 | St. Joseph's Hospital and Medical Center, Phoenix | Phase 2 |
| Recruiting | ENACT Program on Auditory Perception and Function, Cognitive Function and Health-related Quality of Life NCT06955494 | The University of Hong Kong | N/A |
| Not Yet Recruiting | MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairm NCT06177028 | St. Joseph's Hospital and Medical Center, Phoenix | Phase 2 |
| Recruiting | Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biom NCT06669546 | University of Bern | N/A |
| Recruiting | Buddy-Up Dyadic Physical Activity Program for Persons With Dementia and Family Caregivers NCT06584110 | The University of Hong Kong | N/A |
| Completed | Anticipating Decline and Providing Therapy NCT06182995 | Wake Forest University Health Sciences | N/A |
| Completed | Repeated Transcranial Magnetic Stimulation in the Elderly With Cognitive Impairment NCT06192433 | Taipei Hospital, Ministry of Health and Welfare | N/A |
| Completed | Effects of Training Dose on Computerized Cognitive Training in Patients With Cognitive Impairment NCT05922319 | Xuanwu Hospital, Beijing | — |
| Recruiting | Interventions in Mathematics and Cognitive Skills NCT05201534 | Stanford University | N/A |
| Completed | Brain Health Together: A Live-Streaming Group-Based Digital Program NCT05818423 | University of California, San Francisco | N/A |
| Completed | Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial NCT05860127 | University of Massachusetts, Amherst | N/A |
| Active Not Recruiting | A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011) NCT05637801 | Cognito Therapeutics, Inc. | N/A |
| Completed | Transcranial Alternating Current Stimulation (TACS) for Sleep Disturbances in Neurocognitive Disorders Due to NCT05544201 | Chinese University of Hong Kong | N/A |
| Completed | Efficacy of a Mobile-based Multidomain Intervention to Improve Cognitive Function and Health-related Outcomes NCT05675137 | Silvia Health | N/A |
| Completed | Study of a Behavioral Intervention for Older Advanced Cancer Patients and Their Caregivers NCT05200572 | University of Rochester | N/A |
| Unknown | Telerehabilitation Cognitive Impairments Following Chemotherapy Feasibility Study NCT04972019 | Bright Cloud International Corp | N/A |
| Completed | Efficacy of a Multimodal Brain Health Intervention for Older African Americans NCT04863378 | Oregon Health and Science University | N/A |
| Completed | A Practical Platform for In-Home Remote Monitoring of Cognitive Frailty NCT05754021 | Baylor College of Medicine | — |
| Unknown | Robot-assisted Cognitive Training for Lonely Older Adults With Mild Cognitive Impairment (MCI) NCT04051918 | University of Georgia | N/A |
| Completed | The Effect of Multidomain Dietary Education in Type 2 Diabetic Adults NCT05892861 | National Kaohsiung Normal University | N/A |
| Unknown | Effects of Multimodal Training of Combined Cognitive and/or Physical Training on Cognition and Fitness of Olde NCT04727450 | Hong Kong Baptist University | N/A |
| Unknown | Board Games Among Mild Cognitive Impairment Patients Experience (GAME Project) NCT04835909 | Brain In Game scientific-technical service | N/A |
| Recruiting | Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults NCT04262206 | Duke University | Phase 4 |
| Unknown | Online Cognitive Rehabilitation of Executive Dysfunction in Nonamnestic MCI NCT04503798 | Baycrest | N/A |
| Completed | Listen Carefully: An Exploratory Study of the Association Between Listening Effort and Cognitive Function NCT04593290 | Technical University of Denmark | N/A |
| Completed | Associations Between General Movements Assessments and Cognitive Development NCT05217056 | Kahramanmaras Sutcu Imam University | — |
| Completed | MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients NCT04032626 | St. Joseph's Hospital and Medical Center, Phoenix | Phase 2 |
| Completed | Effect of Nordic Berries on Cognitive Function, Cardiometabolic Risk Markers and Gut Microbiota in Adults With NCT04317612 | Region Skane | N/A |
| Completed | Cognition, Age, and RaPamycin Effectiveness - DownregulatIon of thE mTor Pathway NCT04200911 | The University of Texas Health Science Center at San Antonio | EARLY_Phase 1 |
| Completed | Speech, Linguistic and Acoustic Markers in Parkinson's Disease NCT04273672 | University of Massachusetts, Worcester | — |
| Completed | Low Level Laser Therapy Impact on Cognitive Function and Quality of Life in Alzheimer Anemic Elderly Patients NCT04496778 | Cairo University | N/A |
| Completed | KNA Proof-of-Concept NCT04968041 | Florida State University | N/A |
| Active Not Recruiting | Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG) NCT04033510 | David Brunk, PA-C, MMS | — |
| Recruiting | Pharmacological Modulation of Brain Oscillations in Memory Processing NCT05594017 | University of Texas Southwestern Medical Center | EARLY_Phase 1 |
| Suspended | How is COGNItive Function Affected by Cardiac Resynchronisation Therapy? NCT03755570 | Royal Cornwall Hospitals Trust | — |
| Completed | Effects of an Adaptogenic Extract on Electrical Activity of the Brain in Elderly Subjects With Cognitive Impai NCT03780621 | EuroPharma, Inc. | Phase 1 |
| Completed | Walking on Cognitive Function in Individuals With Mild Cognitive Impairment: A Pilot Project NCT04498195 | Samuel Merritt University | N/A |
| Completed | Brain Stimulation and Enhancing Cognition in Older Adults NCT03653351 | Washington University School of Medicine | N/A |
| Completed | Evaluation of Pilot Community-based Multi-domain Program Older Adults at Risk of Cognitive Impairment NCT04440969 | Geriatric Education and Research Institute | N/A |
| Active Not Recruiting | Multi-Center Study of Sensory Stimulation to Improve Brain Function NCT03556280 | Cognito Therapeutics, Inc. | N/A |
| Completed | Are Cognition and Sleep Affected by Exposure to Carbon Dioxide and Bio Effluents During Sleep? NCT03558698 | University of Aarhus | N/A |
| Completed | Comparing Smartphone Technology and a Memory Strategy on Improving Prospective Memory in Alzheimer's Disease NCT03384043 | Baylor University | N/A |
| Completed | Identify the Benefits CAREGIVERSPRO-MMD Platform Use Based on the Information and Communications Technology, D NCT03536975 | University Hospital, Rouen | N/A |
| Completed | Virtual Reality Stimulation to Enhance Cognitive Function of Intensive Care Unit Patients NCT03025373 | Insel Gruppe AG, University Hospital Bern | — |
| Unknown | Does Computerized Cognitive Training Improve Executive Functioning in the Older Adult? NCT03170492 | University of the Sciences in Philadelphia | N/A |
| Unknown | Support Monitoring and Reminder Technology NCT03325699 | Johan Sanmartin Berglund | N/A |
| Completed | Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA) NCT03246269 | Andreas Monsch | — |
| Unknown | Appropriate Compatibility of Propofol and Sevoflurane for Orthopaedic Surgery of Patients With MCI NCT03165396 | The Third Central Clinical College of Tianjin Medical University | N/A |