NCT04273672

Speech, Linguistic and Acoustic Markers in Parkinson's Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 58 (actual)
• Sponsor: University of Massachusetts, Worcester · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The Investigators aim to identify speech and language markers that provide information on cognitive function and predict cognitive decline in Parkinson's disease. The Investigators will administer speech tasks and cognitive assessments to participants with Parkinson's disease and healthy controls. The Investigators will also explore the associations between genetic factors and speech and cognitive status in Parkinson's disease.

Conditions

• Parkinson Disease
• Cognitive Impairment, Mild
• Speech

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cognitive Battery	Participants will be asked to complete a series of cognitive testing (testing of concentration, memory, and other thinking abilities).
BEHAVIORAL	Voice, Speech and Language Analysis	Participants will be asked to perform speaking and reading tasks, which will be recorded. Participants will be asked to complete a laptop-based test of language comprehension.
BEHAVIORAL	Questionnaires and Clinical Assessments	Participants with Parkinson's disease will complete an examination of their symptoms and questionnaires assessing disease symptoms, mood and activities of daily living. Healthy controls participants will be asked to complete questionnaires on mood.
GENETIC	DNA Analysis	Participants will have their blood drawn for DNA analysis.

Timeline

• Start date: 2020-01-13
• Primary completion: 2023-09-01
• Completion: 2025-02-28
• First posted: 2020-02-18
• Last updated: 2025-06-10
• Results posted: 2025-06-10

Locations

1 site across 1 country: United States