NCT05818423

Brain Health Together: A Live-Streaming Group-Based Digital Program

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 208 (actual)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: All
• Age: 55 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to develop and test a comprehensive Brain Health Together program for older adults living with cognitive decline.

Detailed description

Older adults with cognitive decline (including either mild cognitive impairment \[MCI\] or subjective cognitive decline \[SCD\]) represent a large market with important unmet needs. Approximately one in three older adults (18 million Americans) are currently living with cognitive decline, which places them at increased risk of developing Alzheimer's disease and related dementias (ADRD). There are no medications that can prevent development of dementia in people with cognitive decline; however, there is growing evidence that behavioral interventions targeting modifiable dementia risk factors-such as increasing physical activity and reducing social isolation-may help improve cognitive function and could potentially delay dementia onset. Preliminary results suggest that Moving TogetherTM program is associated with significant improvements in cognitive function, physical function, social isolation, and self-regulation as well as increased default mode network connectivity on pre/post resting state functional magnetic resonance imaging scans in people with cognitive decline. The investigators believe that these benefits would be even greater if Moving Together were combined with a comprehensive brain health coaching program.

Conditions

• Mild Cognitive Impairment
• Cognitive Decline
• Cognitive Deterioration
• Cognitive Deficits, Mild
• Cognitive Impairment, Mild

Interventions

Type	Name	Description
BEHAVIORAL	Brain Health Academy	The Brain Health Academy group will review online content about brain health (1 hour, 2 days/week for 12 weeks) and will complete a brief survey after each module to assess compliance (30 hours total).
BEHAVIORAL	Brain Health Together	The Brain Health Together group will participate in online, live-streaming, group-based Moving Together classes (1 hour/week); Brain Health education group classes (1 hour/week) and individual brain health coaching sessions (0.5 hours/week) for 12 weeks (30 hours total).
BEHAVIORAL	Maintain Brain Health Together	The Maintaining Brain Health Together group will participate in the full Brain Health Together program (30 hours) for 12 weeks followed by weekly group classes and six individual coaching for an additional 12 weeks (additional 15 hours).

Timeline

• Start date: 2023-04-10
• Primary completion: 2024-11-30
• Completion: 2024-11-30
• First posted: 2023-04-18
• Last updated: 2024-12-24

Locations

1 site across 1 country: United States