| Recruiting | Repurposing Siponimod for Alzheimer's Disease Alzheimer Disease, Mild Alzheimer Disease, MCI With Increased Risk for Alzheimer Disease | Phase 2 | 2025-08-26 |
| Not Yet Recruiting | MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairm Cognitive Impairment, Mild, Cognitive Dysfunction, Amyloid Plaque | Phase 2 | 2025-06-01 |
| Recruiting | Working Memory Training in Patients with Mild Cognitive Impairment Mild Cognitive Impairment (MCI) | N/A | 2024-09-16 |
| Recruiting | ASSESS ALL ALS Study Amyotrophic Lateral Sclerosis | — | 2024-07-25 |
| Recruiting | PREVENT ALL ALS Study Amyotrophic Lateral Sclerosis | — | 2024-07-25 |
| Enrolling By Invitation | Electrophysiological Recordings from Deep Brain Stimulation Electrodes for Pain Chronic Pain | N/A | 2024-06-11 |
| Recruiting | A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) P High Grade Glioma, Glioblastoma | EARLY_Phase 1 | 2023-10-18 |
| Recruiting | Gentamicin Bladder Instillation on CAUTI Catheter Infection | Phase 4 | 2023-10-09 |
| Recruiting | Time Restricted Eating in Alzheimer's Disease Mild Cognitive Impairment (MCI) | N/A | 2023-03-15 |
| Completed | Exercise in Advanced Parkinson's Disease (PD) With Deep Brain Stimulation (DBS) Parkinson Disease | N/A | 2022-06-01 |
| Completed | Home-based Remote Digital Monitoring to Assess ALS Progression (Track ALS) ALS (Amyotrophic Lateral Sclerosis) | — | 2022-02-21 |
| Terminated | DBS of Posterior Subthalamic Area (PSA) and Ventral Intermediate Nucleus (VIM) in Essential Tremor (ET) Essential Tremor | N/A | 2021-11-30 |
| Enrolling By Invitation | Deep Brain Stimulation (DBS) of the Pedunculopontine Nucleus (PPN) Parkinson Disease | N/A | 2021-11-01 |
| Unknown | Genetic Risk Stratification for Primary Prevention of CAD in Men and Pre & Post-menopausal Women Coronary Artery Disease, Genetic Predisposition to Disease | — | 2021-08-23 |
| Unknown | Radiotherapy Planning Using Fluciclovine PET in Patients With Newly Diagnosed Glioblastoma Newly Diagnosed Glioblastoma | Phase 2 | 2021-06-07 |
| Completed | MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients Cognitive Impairment, Mild, Cognitive Dysfunction, Amyloid Plaque | Phase 2 | 2020-07-22 |
| Suspended | Operative Procedures Vs. Endovascular Neurosurgery for Untreated Pseudotumor Trial Pseudotumor Cerebri, Idiopathic Intracranial Hypertension (IIH) | N/A | 2020-06-03 |
| Unknown | Striatal Dopamine Transporter Density in Post-Traumatic Stress Disorder (PTSD) Post-traumatic Stress Disorder | N/A | 2020-01-01 |
| Withdrawn | VALIDATE: Factor VIII Trending for MS Relapse Multiple Sclerosis | — | 2019-08-13 |
| Completed | A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade G Glioblastoma Multiforme, Glioma of Brain | EARLY_Phase 1 | 2019-01-19 |
| Unknown | Effect of L-Dihydroxyphenylserine (L-DOPS) on Falls in Patients With Neurogenic Orthostatic Hypotension (NOH) Parkinson Disease, Falls Patient | Phase 2 | 2018-08-17 |
| Unknown | Multi-site Validation and Application of a Consensus DSC-MRI Protocol Glioblastoma Multiforme, Gliosarcoma | N/A | 2018-02-01 |
| Terminated | Effect of Oral Propranolol on mRNA Expresssion in Symptomatic Cavernous Malformation Cerebral Cavernous Malformations | Phase 2 | 2018-01-24 |
| Recruiting | Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Antibiotics, Pituitary Adenoma | Phase 4 | 2017-07-01 |
| Unknown | Development and Validation of Advanced MRI Methods for Clinical Applications Brain Tumor | N/A | 2017-06-26 |
| Completed | Relationship Between Down Syndrome (DS) and Alzheimer's Disease (AD) Down Syndrome, Alzheimer's Dementia | N/A | 2016-11-01 |
| Terminated | Deep Brain Stimulation of the nbM to Treat Mild Cognitive Impairment in Parkinson's Disease Parkinson's Disease, Mild Cognitive Impairment | N/A | 2016-09-01 |
| Unknown | Effect of L-Dihydoxyphenylserine on Locomotion, Postural Stability, and Fall Risk Reduction in Parkinson Disea Parkinson Disease | Phase 2 | 2016-05-01 |
| Completed | Post-Operative Water Load Following Transsphenoidal Pituitary Surgery Hyponatremia, Pituitary Adenoma | N/A | 2016-03-07 |
| Completed | Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasis Glioblastoma, Brain Metastases | EARLY_Phase 1 | 2016-02-17 |
| Completed | Electrophysiological Recordings of Deep Brain Stimulation in the Basal Ganglia Parkinson Disease | N/A | 2016-02-01 |
| Completed | A Study on the Safety of Tranexamic Acid for the Chronic Subdural Hematoma Population Subdural Hematoma | Phase 4 | 2015-11-01 |
| Completed | Cerebrospinal Fluid Drainage (CSFD) in Acute Spinal Cord Injury Spinal Cord Injury | N/A | 2015-10-01 |
| Unknown | Genetics of Arteriovenous Malformations Arteriovenous Malformation | — | 2015-05-01 |
| Terminated | Identification of Genomic Changes in Families Having Multiple Members With Tumors Glioma | — | 2015-03-01 |
| Completed | Identification of Novel Molecular Markers for Cerebral Ischemia From Patients With Minor and Devastating Ische Cerebral Ischemia | — | 2015-03-01 |
| Terminated | Micro Ribonucleic Acid (miRNA) Markers of Hydrocephalus in Intraventricular Hemorrhage (IVH) Intraventricular Hemorrhage, Spina Bifida | — | 2015-03-01 |
| Terminated | Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence Cervical Spondylosis, Lumbar Spondylosis | Phase 2 | 2015-03-01 |
| Withdrawn | Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Essential Tremor Essential Tremor | N/A | 2015-02-01 |
| Completed | Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors Pituitary Tumor, Pain | Phase 4 | 2015-02-01 |
| Completed | Transsphenoidal Extent of Resection Study Pituitary Adenoma | N/A | 2015-02-01 |
| Terminated | Trial Comparing Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Parkinson's Disease Parkinson's Disease | N/A | 2015-01-15 |
| Completed | A Phase 0 Study of AZD1775 in Recurrent GBM Patients Glioblastoma, GBM | EARLY_Phase 1 | 2014-07-01 |
| Unknown | 5-ALA in Recurrent Glioma Glioma | N/A | 2014-02-01 |
| Terminated | Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma Glioblastoma (GBM) | Phase 1 / Phase 2 | 2013-10-01 |
| Terminated | Tumor Resection and Gliadel® Wafers, Followed by Temodar® With Standard Radiation or GammaKnife® for New GBM Glioblastoma | Phase 1 / Phase 2 | 2013-05-07 |
| Completed | Intraoperative Brachytherapy for Central Nervous System Lesions: A Validation Study of a Radioactive Seed Load Central Nervous System Lesion | — | 2013-04-02 |
| Unknown | Deep Brain Stimulation (DBS) Data Base Study Parkinson's Disease, Essential Tremor | — | 2013-04-01 |
| Terminated | Neurocognitive Effects of Bilateral STN Versus GPi DBS in Parkinson's Disease Patients With MCI Parkinson's Disease, Mild Cognitive Impairment, Dementia | N/A | 2013-04-01 |
| Completed | Evaluating the Impact That Personnel Traffic Through the Operating Room Has on Surgical Site Infections Neurological Diseases | N/A | 2013-03-01 |
| Unknown | Evaluation of Onfi Conversion Therapy Replacing Clonazepam in Patients With Medically Refractory Epilepsy Refractory Epilepsy | Phase 4 | 2013-02-01 |
| Completed | DBS Under General Anesthesia: Comparison To The Standard Technique Parkinson's Disease | — | 2012-11-01 |
| Terminated | Nuedexta in the Treatment of Pseudobulbar Affect in Patients With Alzheimer's Disease Alzheimer's Disease, Pseudobulbar Affect (PBA) | Phase 4 | 2012-08-28 |
| Completed | Dural Graft Equivalent Comparison Trial Chiari Malformation | N/A | 2012-01-18 |
| Completed | Rhinological Outcomes in Endonasal Pituitary Surgery Pituitary Neoplasm, Pituitary Adenoma, Prolactinoma | — | 2011-10-01 |
| Withdrawn | Uterine Electrical Activity Before and After Progesterone Treatment for Preterm Labor Preterm Labor | N/A | 2011-07-01 |
| Completed | Fluorescence-guided Surgery for Low- and High-grade Gliomas Glioma | Phase 3 | 2010-11-01 |
| Completed | Barrow Nasal Inventory Survey Pituitary Tumors | — | 2010-10-01 |
| Completed | Identification of Novel Molecular Markers for Vasospasm Cerebral Vasospasm, Subarachnoid Hemorrhage | — | 2010-09-01 |
| Completed | Chlorhexidine Gluconate Oral Care for Adults Experiencing Trauma Ventilator Associated Pneumonia | N/A | 2010-07-01 |
| Completed | Effects of Oral Care in the Neuroscience ICU Ventilator Associated Pneumonia, Oral Hygiene | N/A | 2007-05-01 |
| Unknown | Barrow Ruptured Aneurysm Trial Ruptured Cerebral Aneurysm, Subarachnoid Hemorrhage (SAH) | N/A | 2002-11-01 |
| Terminated | Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy IgA Nephropathy | Phase 3 | 2002-01-01 |