NCT01382446

Chlorhexidine Gluconate Oral Care for Adults Experiencing Trauma

Evaluating Effectiveness of Chlorhexidine Gluconate Oral Care for Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (actual)
• Sponsor: St. Joseph's Hospital and Medical Center, Phoenix · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Examine the use of 0.12% Chlorhexidine Gluconate as an adjunct to current oral care protocol for trauma patients on ventilator support to decrease the incidence of Ventilator Associated Pneumonia and oral bacterial load.

Detailed description

To see a significant decrease in the bacterial load in the oral mucosa and subsequently, a decrease in the pathogenesis of Ventilator Associated Pneumonia through the use of an oral rinse containing 0.12% Chlorhexidine Gluconate as part of an oral care protocol. Current oral care protocol includes the use of 1.5% H2O2-coated swabs every four hours, toothbrushing with toothpaste every 12 hours, and use of continuous subglottic suction apparatus.

Conditions

• Ventilator Associated Pneumonia

Interventions

Type	Name	Description
DRUG	Chlorhexidine gluconate	0.12% Chlorhexidine Gluconate 15ml Twice Daily, administered via toothbrushing and swabbing teeth, tongue, gingiva, and oral mucosa.
OTHER	Toothpaste	Brushing the teeth, tongue, gingiva, and oral mucosa twice daily with toothbrush and toothpaste.

Timeline

• Start date: 2010-07-01
• Primary completion: 2012-04-01
• Completion: 2012-04-01
• First posted: 2011-06-27
• Last updated: 2017-02-06
• Results posted: 2013-11-28

Locations

1 site across 1 country: United States