Trials / Not Yet Recruiting
Not Yet RecruitingNCT06566183
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial
ISCHEMIA-LVD: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial
- Status
- Not Yet Recruiting
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 1,200 (estimated)
- Sponsor
- NYU Langone Health · Academic / Other
- Sex
- All
- Age
- 55 Years
- Healthy volunteers
- Not accepted
Summary
The ISCHEMIA-HF trial will randomize participants with multivessel coronary artery disease (CAD) with ejection fraction (EF) ≤40% in a 1:2:2 fashion to guideline-directed medical therapy (GDMT):coronary artery bypass grafting (CABG):percutaneous coronary intervention (PCI).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Guideline-directed medical therapy (GDMT) | Participants receive guideline-directed medical therapy (GDMT). |
| PROCEDURE | Coronary artery bypass grafting (CABG) | Participants receive coronary artery bypass grafting (CABG). |
| PROCEDURE | Percutaneous coronary intervention (PCI). | Participants receive percutaneous coronary intervention (PCI). |
Timeline
- Start date
- 2026-12-01
- Primary completion
- 2030-12-01
- Completion
- 2032-12-01
- First posted
- 2024-08-22
- Last updated
- 2025-07-03
Locations
6 sites across 6 countries: United States, Brazil, India, Mexico, Poland, South Korea
Source: ClinicalTrials.gov record NCT06566183. Inclusion in this directory is not an endorsement.