| Not Yet Recruiting | Dynamic Treatment Regimes for Opioid Use Disorder Opioid Use Disorder | Phase 2 | 2028-07-01 |
| Not Yet Recruiting | Digital Tools to Engage and Activate Patients During Hospitalization Hospital Information Systems | N/A | 2028-07-01 |
| Suspended | Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE Pulmonary Embolism, Right Ventricular Dysfunction, Right Ventricular Failure | — | 2027-01-01 |
| Not Yet Recruiting | Randomized Trial of a Sleep Disorders Program on Firefighter Safety and Disability ... Sleep Disorder | N/A | 2027-01-01 |
| Not Yet Recruiting | Computerized Decision Support to Prevent Stroke in Atrial Fibrillation Atrial Fibrillation, Stroke | N/A | 2026-12-30 |
| Withdrawn | Fatty Acids in Airway Smooth Muscle of Asthmatics Asthma | N/A | 2026-11-01 |
| Suspended | Evaluation of Hemodynamics in People With Untreated Preeclampsia Using Echocardiography Preeclampsia | — | 2026-10-25 |
| Not Yet Recruiting | Does Circadian Misalignment Have Sex-Specific Effects on Metabolism? Circadian Misalignment, Sex Differences | N/A | 2026-10-01 |
| Not Yet Recruiting | Pilot Trial of Xylitol for C. Difficile De-Colonization in Patients With Inflammatory Bowel Disease Inflammatory Bowel Disease (IBD), Clostridioides Difficile Infection | EARLY_Phase 1 | 2026-09-01 |
| Not Yet Recruiting | Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients With Inflammatory Bow Inflammatory Bowel Disease (IBD), Clostridioides Difficile Infection | Phase 4 | 2026-09-01 |
| Not Yet Recruiting | Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss Obesity, Obesity, Morbid, Metabolic Disease | N/A | 2026-09-01 |
| Not Yet Recruiting | Sonication-based OCD Neurosurgical Intervention Via Capsulotomy Obsessive-Compulsive Disorder | Phase 1 / Phase 2 | 2026-08-01 |
| Not Yet Recruiting | Xylitol Use for Decolonization of C. Difficile in Patients With IBD Inflammatory Bowel Diseases, Clostridioides Difficile Infection | Phase 1 | 2026-08-01 |
| Not Yet Recruiting | Neprilysin Inhibition to Reduce Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction Heart Failure With Preserved Ejection Fraction, Myocardial Fibrosis | Phase 4 | 2026-07-01 |
| Not Yet Recruiting | CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock Cardiogenic Shock, Heart Failure, Inflammation | Phase 2 | 2026-07-01 |
| Not Yet Recruiting | Tirzepatide for the Treatment of Cannabis Use Disorder Cannabis Use Disorder | Phase 2 | 2026-07-01 |
| Not Yet Recruiting | Improving the Quality of Care for Asthma Patients at Risk of Exacerbations Asthma, Asthma Chronic, Asthma Severe Persistent With Exacerbation | N/A | 2026-07-01 |
| Not Yet Recruiting | Impacts of Opioids on Respiratory Drive During Sleep Opioids, Obstructive Sleep Apnea (OSA) | EARLY_Phase 1 | 2026-07-01 |
| Not Yet Recruiting | Development of a Multilevel HIV Prevention Intervention for the Emergency Department HIV, Drug Use, Mental Health | N/A | 2026-06-01 |
| Not Yet Recruiting | Cenobamate in the Intensive Care Unit Epilepsy, Neurologic Disorder | EARLY_Phase 1 | 2026-06-01 |
| Not Yet Recruiting | Reducing Heart Failure Risk in Late-Life With Physical Activity Hypertension, Exercise Training, Cardiac Rehabilitation | N/A | 2026-06-01 |
| Not Yet Recruiting | Harmonized Healing: Personalized Music Interventions to Address Chronic Pain in People Living With HIV Chronic Pain, Hiv | N/A | 2026-06-01 |
| Not Yet Recruiting | WELL-MPN: A Digital Lifestyle App for Patients With MPNs Myeloproliferative Neoplasms (MPNs) | N/A | 2026-06-01 |
| Not Yet Recruiting | Ropeginterferon for High Risk JAK2 Clonal Hematopoiesis JAK2 Mutation | Phase 1 | 2026-06-01 |
| Not Yet Recruiting | Korus: a Device to Prevent Sudden Unexpected Death in Epilepsy (SUDEP) Epilepsy | N/A | 2026-05-15 |
| Not Yet Recruiting | Testing the Impact of Pre-visit Priming for Medications Deprescribing, Statin Prescribing | N/A | 2026-05-15 |
| Not Yet Recruiting | N-of-1 Trial to Promote Beta-Blocker Titration in Heart Failure Heart Failure, Beta-blocker, Older Adults | N/A | 2026-05-05 |
| Not Yet Recruiting | Addressing the Double Burden of Malnutrition in Guatemala Maternal Obesity Complicating Pregnancy, Birth,or Puerperium, Child Malnutrition | N/A | 2026-05-01 |
| Not Yet Recruiting | Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control Hypertension, Primary Care | N/A | 2026-05-01 |
| Not Yet Recruiting | Community-Based Engagement to Improve Lung Cancer Screening and Outcomes: The "Our Lungs Our Health" Study Lung Cancer Screening | N/A | 2026-05-01 |
| Not Yet Recruiting | Imaging- vs. Scalp-Targeted Accelerated TMS for Depression: The Number Needed to Scan Trial Major Depressive Disorder (MDD) | N/A | 2026-05-01 |
| Not Yet Recruiting | Developing an HIV Disclosure Intervention for Men in Uganda HIV Infections, Sexually Transmitted Infections (Not HIV or Hepatitis) | N/A | 2026-05-01 |
| Not Yet Recruiting | Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder Alcohol Use Disorder | Phase 2 | 2026-05-01 |
| Recruiting | IntelliWell: An AI-Assisted Imaging Platform for Detection and Location of Ultra-Rare Testicular Sperm in Surg Infertility, Azoospermia | N/A | 2026-04-15 |
| Not Yet Recruiting | Colchicine to Reduce Your SympToms And Lower Levels of Inflammation, Zeroing in on Effective CPPD Disease Trea CPPD - Calcium Pyrophosphate Deposition Disease | Phase 2 | 2026-04-10 |
| Not Yet Recruiting | Acute Hospital Care at Home for People Living With Dementia Emergency Department Visit, Home Care Services, Dementia | N/A | 2026-04-01 |
| Not Yet Recruiting | Statins to Prevent Cancer Associated Blood Clots Venous Thromboembolism, Cancer, Cardiovascular Events | Phase 4 | 2026-04-01 |
| Not Yet Recruiting | Strategies to Decentralize Breast Ultrasound in Rwanda Breast Cancer, Early Detection of Cancer, Ultrasonography | N/A | 2026-04-01 |
| Not Yet Recruiting | Evaluation of Sex Differences in Glucose Metabolism in Response to Sleep Curtailment Sleep Deprivation, Sex Differences, Glucose Tolerance | N/A | 2026-04-01 |
| Not Yet Recruiting | Photobiomodulation, Heart Rate Variability, and Acute Stress Stress | N/A | 2026-04-01 |
| Not Yet Recruiting | Chiropractic Care for Chronic Neck Pain: A Pilot Study Neck Pain | N/A | 2026-04-01 |
| Not Yet Recruiting | NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome Down Syndrome (DS) | Phase 1 | 2026-04-01 |
| Not Yet Recruiting | Nicotinamide Mononucleotide in Patients Undergoing CABG Surgery Coronary Artery Bypass Graft | Phase 2 | 2026-03-31 |
| Not Yet Recruiting | Sleep, Light, Circadian, Central Oxidative Stress Non-visual Effects of Light, Chronic Variable Sleep Deficiency | N/A | 2026-03-30 |
| Recruiting | Post-Surgery Wound Healing Tracking With MyHealthPal App Wound Infection and Wound Healing | N/A | 2026-03-27 |
| Active Not Recruiting | Emulation of the CheckMate 017/057 (NCT01642004 and NCT01673867) Trials Using Specialty Oncology Electronic He Advanced Non-squamous Non-small-cell Lung Cancer, Advanced Non-Small Cell Squamous Lung Cancer | — | 2026-03-12 |
| Active Not Recruiting | Emulation of the KEYNOTE-042 (NCT02220894) Trial Using Specialty Oncology Electronic Health Records Databases Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) | — | 2026-03-12 |
| Not Yet Recruiting | TMS With Real-time E-field and EEG Source Imaging Healthy Volunteers Only | N/A | 2026-03-01 |
| Not Yet Recruiting | Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria Proteinuric Renal Disease, Proteinuric Kidney Disease, Proteinuria | Phase 1 | 2026-03-01 |
| Recruiting | Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES) Opioid Consumption, Postoperative, Multimodal Analgesia, Robotic Assisted Laparoscopic Surgery | Phase 3 | 2026-03-01 |
| Not Yet Recruiting | Large Language Model-Generated Messages to Improve Guideline-Directed Medical Therapy in Heart Failure Heart Failure | N/A | 2026-03-01 |
| Not Yet Recruiting | STABLE Pilates for Hypermobility Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS), Hypermobile Spectrum Disorder | N/A | 2026-03-01 |
| Recruiting | Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms Menopausal Women, Insomnia | Phase 4 | 2026-02-13 |
| Active Not Recruiting | Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data. Type 2 Diabetes | — | 2026-02-03 |
| Active Not Recruiting | The Use of Artificial Intelligence Generated Contours in Radiation Planning of the Prostate Brachytherapy Prostate Cancer | N/A | 2026-02-03 |
| Not Yet Recruiting | Dapagliflozin in Active Lupus Nephritis Lupus Nephritis (LN) | Phase 4 | 2026-02-01 |
| Recruiting | Mindfulness Meditation for Insomnia Sleep Initiation and Maintenance Disorders, Insomnia, Insomnia Chronic | Phase 1 / Phase 2 | 2026-02-01 |
| Recruiting | Yoga for Persistent Post-Surgical Pain (PPSP) Persistent Post-surgical Pain | N/A | 2026-01-31 |
| Not Yet Recruiting | Aromatherapy to Address Psychological Distress in Emergency Department Patients. Aromatherapy, Anxiety, Stress | N/A | 2026-01-30 |
| Active Not Recruiting | INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASC Type 2 Diabetes, Overweight, ASCVD | — | 2026-01-27 |
| Active Not Recruiting | Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserv Type 2 Diabetes, Heart Failure | — | 2026-01-24 |
| Recruiting | OsteoPorotic fracTure preventION System (OPTIONS) Research Study Osteoporosis, Lower Limb Fracture | N/A | 2026-01-16 |
| Recruiting | Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Ca Psychosis, Anxiety, Depression | N/A | 2026-01-05 |
| Recruiting | Efficacy of Routine Saline Flushing in the Prevention of Nephrostomy Tube Obstructions: A Pilot Study Nephrostomy | N/A | 2026-01-01 |
| Recruiting | Targeted Accelerated TMS for Post-Traumatic Stress Disorder Post Traumatic Stress Disorder (PTSD) | N/A | 2025-12-15 |
| Active Not Recruiting | Photobiomodulation for the Prevention of Oral Mucositis Oral Mucositis | Phase 2 | 2025-12-01 |
| Recruiting | The SUSTAIN 2 Study - SUStained HIV Treatment for Adherence After Interruption in Care Human Immunodeficiency Virus | N/A | 2025-11-14 |
| Active Not Recruiting | A Trial of Academic Detailing to Promote Prescribing of Biosimilars Autoimmune Diseases, Rheumatoid Arthritis (RA), Inflammatory Bowel Disease (IBD) | N/A | 2025-11-06 |
| Recruiting | Targeted Naltrexone to Support Individuals Participating in Dry January Alcohol Misuse | Phase 2 | 2025-11-03 |
| Completed | Emulation of the MONARCH-3 Trial Using Specialty Oncology Electronic Health Records Databases Advanced Breast Cancer | — | 2025-11-03 |
| Recruiting | Self-regulation of Real-time fMRI Brain Activity in Chronic Pain Fibromyalgia | N/A | 2025-10-31 |
| Recruiting | Extended-release Buprenorphine as a Novel Low-dose Induction Strategy Opioid Use Disorder | Phase 2 | 2025-10-27 |
| Recruiting | Open Label Treprostinil Raynaud's Study Raynaud's Disease, Raynaud Phenomena, Raynauds | Phase 4 | 2025-10-15 |
| Active Not Recruiting | Mortality Benefit of Ultrasound for Thyroid Nodules Identified With PET Imaging: Non-Inferiority Emulated Targ Thyroid Nodule (Benign), Thyroid Nodule (Diagnosis), Thyroid Cancer | — | 2025-10-15 |
| Enrolling By Invitation | Improving Lipid Optimization Quality and Treatment Options in ASCVD Hypercholesterolemia, ASCVD | N/A | 2025-10-14 |
| Recruiting | Losartan to Improve Outcomes After Multi-ligament Knee Injury Multi-ligament Knee Injury | Phase 2 | 2025-10-01 |
| Recruiting | Study of Novel Therapeutics for Acute Remedy of Colitis Ulcerative Colitis, Ulcerative Colitis Chronic Moderate, Ulcerative Colitis Chronic Severe | Phase 2 | 2025-09-30 |
| Completed | Comparative Effectiveness of Tirzepatide Versus Sitagliptin in Individuals at Cardiovascular Risk (TIRZSITA-CV Type2 Diabetes Mellitus, Atherosclerotic Cardiovascular Disease | — | 2025-09-19 |
| Recruiting | Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease Dementia, Alzheimers Disease, Mild Cognitive Impairment Due to Alzheimer's Disease | Phase 2 | 2025-09-16 |
| Recruiting | Study of Tirzepatide for Recovery and Alcohol Use Management Alcohol Use Disorder (AUD) | Phase 2 | 2025-09-15 |
| Recruiting | Assessment of the Feasibility of Using a Preoperative Surgical Fracture Analysis Tool Tibia Fractures, Trauma (Including Fractures), Surgical Planning | N/A | 2025-09-10 |
| Not Yet Recruiting | Personalizing A1c Using Hematologic Indices and CGM for Accurate Diabetes Diagnosis Type 2 Diabetes | — | 2025-09-01 |
| Completed | Using Reinforcement Learning to Personalize Electronic Health Record Tools to Facilitate Deprescribing Aging | N/A | 2025-08-11 |
| Recruiting | Accelerated TMS for Perinatal Depression Perinatal Depression, Post Partum Depression, Major Depressive Disorder | N/A | 2025-08-05 |
| Recruiting | Quality of Life in Patients With Postoperative Atrial Fibrillation After Cardiac Surgery Postoperative Atrial Fibrillation | — | 2025-07-15 |
| Active Not Recruiting | Emulation of the PALOMA-2 Trial Advanced Breast Cancer | — | 2025-07-14 |
| Recruiting | Cerebral/ Cortical Visual Impairment: Screening, Identification and Outcome Prediction in Neonates Preterm Less Than 32wks With IVH, WMI/PVL, Late Preterm or Term (37-42wks) With Neonatal Encephalopathy Treated With Hypothermia for HIE | — | 2025-07-07 |
| Enrolling By Invitation | RCT of Home-based vs Formal Physical Therapy for Treatment of New Onset Non-insertional Achilles Tendinopathy Achilles Tendinopathy | N/A | 2025-07-01 |
| Recruiting | Group Medical Visits and Chiropractic Care for Older Adults With Chronic Spine Pain Chronic Pain, Musculoskeletal Pain | N/A | 2025-07-01 |
| Recruiting | The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study Ischemic Heart Disease (IHD), Cardiac Magnetic Resonance Imaging, Myocardial Blood Flow | N/A | 2025-06-27 |
| Recruiting | Cocoa Extract for Migraine Trial Migraine | N/A | 2025-06-23 |
| Recruiting | Evaluating Informatics-assisted Immune-related Adverse Event Detection to Improve Registration Onto a Biorepos Malignancy, Immune Related Adverse Events | Phase 1 / Phase 2 | 2025-06-17 |
| Completed | Pilot Study of Real-Time Blood Pressure Decision Support During Cesarean Delivery Under Spinal Anesthesia Spinal Hypotension | N/A | 2025-06-16 |
| Recruiting | Semaglutide for Helping Opioid Recovery Opioid Use Disorder | Phase 2 | 2025-06-02 |
| Recruiting | Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy Postoperative Pain | Phase 2 | 2025-06-01 |
| Recruiting | Glucose Consumption in MS Using [F-18]FDG-PET Multiple Sclerosis | Phase 4 | 2025-05-31 |
| Recruiting | Short Course Radiation Treatment for Patients With Primary or Locally Recurrent Retroperitoneal Sarcoma Prior Retroperitoneal Sarcoma | Phase 1 | 2025-05-29 |
| Active Not Recruiting | Trial of Pistachio Consumption in Older Adults Cognition, Cardiometabolic Risk Factors, Life Satisfaction | N/A | 2025-05-28 |
| Recruiting | Treatment of UC With Novel Therapeutics Ulcerative Colitis Mild, Ulcerative Colitis | Phase 2 | 2025-05-27 |
| Recruiting | Assessment of Circuit Rebreathing During CPAP Therapy Obstructive Sleep Apnea (OSA) | N/A | 2025-05-27 |
| Recruiting | Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Ra Lung Cancer (NSCLC), Geriatric Assessment, Stereotactic Body Radiation Therapy (SBRT) | N/A | 2025-05-26 |
| Recruiting | The Impact of Music Medicine on Preterm Brain Development and Behavior Infant Development, Language Development, Prematurity | N/A | 2025-05-19 |
| Recruiting | Assessment of Synaptic Density in MS Multiple Sclerosis | EARLY_Phase 1 | 2025-05-14 |
| Recruiting | Acceptance and Commitment Therapy to Improve Disability in Chronic Migraine Chronic Migraine | N/A | 2025-04-21 |
| Completed | Effect of Music on Cue Reactivity for Patients With Opioid Use Disorder Opioid Use Disorder | N/A | 2025-04-20 |
| Recruiting | Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial Glioblastoma (GBM) | Phase 2 | 2025-04-14 |
| Completed | Brief Intervention for Chronic Pain and History of Stressful Experiences Chronic Pain, Trauma, Adverse Childhood Experiences | N/A | 2025-04-14 |
| Recruiting | Computerized Decision Support for Identification and Management of Familial Hypercholesterolemia Familial Hypercholesterolaemia | N/A | 2025-04-01 |
| Recruiting | Chiropractic Care for Episodic Migraine Episodic Migraine | N/A | 2025-03-22 |
| Active Not Recruiting | Refinement and Testing of Recruitment Methodology for Behavioral Medication Adherence Interventions Using Beha Diabetes, Pharmacist-Patient Relations, Medication Adherence | N/A | 2025-03-03 |
| Recruiting | The Anabolic Effect of Testosterone on Pelvic Floor Muscles Stress Urinary Incontinence, Menopause | Phase 2 | 2025-02-15 |
| Recruiting | Safety and Feasibility of Tele-supervised Home-based Transcranial Direct Current Stimulation in Parkinson's Di Parkinson Disease | N/A | 2025-02-06 |
| Recruiting | Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia | Phase 2 | 2025-01-30 |
| Enrolling By Invitation | Synergy Between Patient and Clinician: Using a Trauma-Informed Care Plan Trauma and Stressor Related Disorders, Violence, Structural, Violence, Domestic | N/A | 2025-01-17 |
| Recruiting | Embolization Treatment of Chronic Refractory Shoulder Tendinopathy Shoulder Pain, Tendinopathy, Rotator Cuff Tendinitis | N/A | 2025-01-16 |
| Completed | Emulation of the STEP-HFpEF DM Heart Failure Trial in Healthcare Claims Data Diabetes Mellitus, Type 2, HFpEF - Heart Failure With Preserved Ejection Fraction | — | 2025-01-14 |
| Completed | Comparative Effectiveness of Tirzepatide Versus Semaglutide in Individuals With Heart Failure With Preserved E Diabetes Mellitus, Type 2, HFpEF - Heart Failure With Preserved Ejection Fraction | — | 2025-01-14 |
| Completed | Emulation of the SUMMIT Heart Failure Trial in Healthcare Claims Data Diabetes Mellitus, Type 2, Heart Failure With Preserved Ejection Fraction (HFPEF) | — | 2025-01-14 |
| Recruiting | Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Faciliti Aging, Cognitive Impairment, Sleep | N/A | 2025-01-01 |
| Active Not Recruiting | Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure Type 2 Diabetes, Heart Failure | — | 2025-01-01 |
| Recruiting | Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors Hematopoietic Stem Cell Transplant | N/A | 2024-12-17 |
| Recruiting | Can Food Timing Reduce Your Diabetes Risk? Dietary Habits | N/A | 2024-12-10 |
| Recruiting | Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans Appetitive Behavior, Obesity | N/A | 2024-12-05 |
| Enrolling By Invitation | Virtual Reality to Combat Weight-Based Implicit Bias: BWH Pilot Study Implicit Bias, Implicit Association Test | N/A | 2024-11-19 |
| Recruiting | Dolutegravir Pharmacokinetics During Weekly Rifapentine/Isoniazid for TB Prevention Pediatric HIV Infection, Latent Tuberculosis | Phase 1 | 2024-11-15 |
| Recruiting | Eating to Adjust the Timing System Dietary Intervention | N/A | 2024-11-08 |
| Active Not Recruiting | Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Even Type 2 Diabetes | — | 2024-11-01 |
| Recruiting | Elranatamab in Patients With Relapsed or Refractory AL Amyloidosis AL Amyloidosis | Phase 1 / Phase 2 | 2024-11-01 |
| Completed | Emulation of the FLAURA (NCT02296125) Trial Using Specialty Oncology Electronic Health Records Databases Non Small Cell Lung Cancer | — | 2024-10-30 |
| Completed | Emulation of the SOUL Diabetes Trial in Healthcare Claims Diabetes Mellitus, Type 2 | — | 2024-10-24 |
| Completed | Emulating the PIONEER6 Diabetes Trial Using Healthcare Claims Diabetes Mellitus, Type 2 | — | 2024-10-24 |
| Completed | Emulation of the SUSTAIN6 Diabetes Trial Using Healthcare Claims Diabetes Mellitus, Type 2 | — | 2024-10-24 |
| Recruiting | Effect of Physical Activity Pattern on Cardiometabolic Health Life Style | N/A | 2024-10-11 |
| Terminated | Posterior Wall Substrate Modification Using Irreversible Electroporation for Paroxysmal Atrial Fibrillation Atrial Fibrillation Paroxysmal | N/A | 2024-10-08 |
| Recruiting | Care Transitions App for Patients With Multiple Chronic Conditions Heart Failure, Congestive Heart Failure, Diabetes | N/A | 2024-10-08 |
| Withdrawn | Assessment of Fit of Novel N95 Style Transparent Face Masks Respiratory Disease, Infection, Coronavirus, Respiratory Tract Infections | N/A | 2024-10-01 |
| Completed | Prediction of the SURPASS-CVOT Cardiovascular Outcome Trial in Healthcare Claims Data Type 2 Diabetes, Major Adverse Cardiac Events, Cardiovascular (CV) Risk | — | 2024-10-01 |
| Completed | Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular Risk Type 2 Diabetes, Overweight, Cardiovascular (CV) Risk | — | 2024-10-01 |
| Enrolling By Invitation | Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families Water, Child Nutrition, Family Dynamics | N/A | 2024-09-18 |
| Active Not Recruiting | Better Understanding Patient Perspectives of an Educational Tool for Postpartum Hypertensive Patients Hypertension, Pregnancy Induced | N/A | 2024-09-18 |
| Not Yet Recruiting | Development of a Silica Microparticle Taggant System to Measure ART Adherence Hiv, Medication Adherence, Compliance, Medication | N/A | 2024-09-15 |
| Recruiting | LIFT: Life Improvement Trial ME/CFS, Long COVID, PASC | Phase 2 | 2024-09-10 |
| Active Not Recruiting | Testing a Transdiagnostic TMS Treatment Target Major Depressive Disorder, Depression, Psychiatric Disorder | EARLY_Phase 1 | 2024-09-09 |
| Recruiting | The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study Rheumatoid Arthritis (RA, Atherosclerotic Cardiovascular Disease (ASCVD) | — | 2024-09-04 |
| Completed | Biomarkers of AKI in Patients Receiving Daratumumab Acute Kidney Injury, Multiple Myeloma, Light Chain Nephropathy | — | 2024-09-01 |
| Not Yet Recruiting | Epidural Stimulation for Upper Extremity Function Spinal Cord Injury Cervical, Tetraplegia | N/A | 2024-09-01 |
| Completed | A Single-Dose, Three-Way, Three-Sequence, Crossover BA Study of Azithromycin Oleogel Infectious Disease, Drug Effect, Clinical Infection | Phase 1 | 2024-08-08 |
| Not Yet Recruiting | Connectomic Targeted TMS Target for Refractory Anxiety Anxiety Disorders, Mental Disorder, Psychiatric Disorder | Phase 2 | 2024-08-01 |
| Completed | Deprescribing in Patients Living With Dementia With Caregiver and Provider Nudges Alzheimer Disease, Mild Cognitive Impairment, Dementia | N/A | 2024-08-01 |
| Completed | Dexmedetomidine Infusion and Postoperative Lung Aeration After Thoracic Surgery Surgery-Complications, Respiratory Complication, Lung Injury, Acute | N/A | 2024-08-01 |
| Recruiting | AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention Coronary Artery Disease | N/A | 2024-07-31 |
| Suspended | Multi-level School-based Intervention to Improve HPV Vaccine Uptake and Completion in South Africa HPV | N/A | 2024-07-26 |
| Recruiting | Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens Lung Cancer, Lymph Node Metastasis, Pathologic Processes | N/A | 2024-07-26 |
| Recruiting | Exercise Training in Transthyretin Cardiac Amyloidosis Amyloid Cardiomyopathy, Transthyretin Cardiac Amyloidosis | N/A | 2024-07-10 |
| Recruiting | Understanding the Acute Pain Phenotype in Patients Undergoing Surgery Acute Pain, Chronic Post Operative Pain, Opioid Use | — | 2024-07-03 |
| Not Yet Recruiting | Spinal Cord Stimulation for Lower Extremity Function Spinal Cord Injury | N/A | 2024-07-01 |
| Active Not Recruiting | PSMAtrack-tracking Changes in PSMA-PET During Initial Therapy for Metastatic Hormone-sensitive Prostate Cancer Metastatic Prostate Cancer, Hormone Sensitive Prostate Cancer, Metastatic Hormone-sensitive Prostate Cancer (mHSPC) | Phase 4 | 2024-06-30 |
| Terminated | Ketamine for OUD and Suicidal Ideation in the ED Opioid Use Disorder, Suicidal Ideation | Phase 2 | 2024-06-14 |
| Completed | Oral Buprenorphine as a Novel Low-dose Induction Strategy for Opioid Use Disorder Opioid Use Disorder | Phase 1 | 2024-06-04 |
| Active Not Recruiting | Skilled Nursing Facility Care at Home Skilled Nursing Facility, Rehabilitation | N/A | 2024-06-03 |
| Recruiting | Experiment 3: Mixed vs Blocked; Dashboard Paradigm Vision, Healthy, Attention | N/A | 2024-06-01 |
| Recruiting | Mixed Vs Blocked Search: Four Unique Tasks Vision, Healthy, Attention | N/A | 2024-06-01 |
| Recruiting | Experiment 2: One Target in Many Situations Vision, Healthy, Attention | N/A | 2024-06-01 |
| Recruiting | Novel Treatments in Improving Renal Outcomes in Light Chain Cast Nephropathy Multiple Myeloma, Light Chain Nephropathy, Acute Kidney Injury | — | 2024-06-01 |
| Active Not Recruiting | fMRI in CardiaC arrEst With Uncertain Prognosis Cardiac Arrest | — | 2024-05-16 |
| Recruiting | Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease Type 2 Diabetes, Chronic Kidney Diseases | EARLY_Phase 1 | 2024-05-15 |
| Recruiting | Study on Allopregnanolone and Depression in Women Across the Menopause Transition Depression | N/A | 2024-05-14 |
| Recruiting | Ergonomics in the Cardiac Catheterization Laboratory Ergonomics, Orthopedic Injury, Wellness | — | 2024-05-13 |
| Enrolling By Invitation | Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometab Sleep Apnea, Insomnia, Sleep Deprivation | — | 2024-05-08 |
| Recruiting | Preventing Injured Knees From osteoArthritis: Severity Outcomes Osteoarthritis, Knee, Post-traumatic Osteoarthritis, ACL Tear | Phase 2 | 2024-05-06 |
| Completed | Mindfulness Intervention for Fibromyalgia Delivered Through a Smartphone App Fibromyalgia | N/A | 2024-05-03 |
| Recruiting | LIROH - Liraglutide for Obesity in HIV Obesity, HIV Infections | Phase 4 | 2024-05-02 |
| Active Not Recruiting | Magnetic Bead Tracking System and eOPRA Implant System With Bionic Prosthesis for Transtibial Amputees Amputation | N/A | 2024-05-01 |
| Completed | Bahir Dar Child Development Study, Ethiopia Development, Child, Behavior, Social | — | 2024-04-29 |
| Active Not Recruiting | Time-limited Trials in the Emergency Department Emergencies | N/A | 2024-04-12 |
| Active Not Recruiting | Improving Virtual Care of Arthritis: Integrating a Smartphone App Into the EHR for Improved Timeliness of Visi Arthritis, Psoriatic Arthritis | N/A | 2024-04-11 |
| Recruiting | A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomicall Insomnia | N/A | 2024-04-02 |
| Recruiting | Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan Prostate Cancer, Metastatic Castration-resistant Prostate Cancer, Metastatic Castration-resistant Prostate Carcinoma | Phase 4 | 2024-04-01 |
| Recruiting | Digital Health Navigation for Latino Patients With Type II Diabetes Type 2 Diabetes | N/A | 2024-03-31 |
| Withdrawn | Transoral Incisionless Fundoplication (TIF) for Laryngopharyngeal Reflux (LPR) Patients Gastroesophageal Reflux Disease (GERD), Laryngopharyngeal Reflux (LPR), Reflux Disease, Gastro-Esophageal | — | 2024-03-30 |
| Completed | Anti-Platelets in Chronic Obstructive Pulmonary Disease COPD, Emphysema, Emphysema or COPD | Phase 2 | 2024-03-27 |
| Recruiting | Reversible Effect of Falling Ventilatory Drive in Drive-dependent OSA OSA | N/A | 2024-03-27 |
| Active Not Recruiting | Electronic Alert to Improve Testing For Primary Aldosteronism in Patients With Hypertension Primary Aldosteronism, Resistant Hypertension, Secondary Hypertension | N/A | 2024-03-13 |
| Recruiting | Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language Models Comparing Manual and AI Patient Screening in Heart Failure | — | 2024-03-04 |
| Active Not Recruiting | Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45 Migraine, Menstrual Migraine, Menstrually Related Migraine | Phase 4 | 2024-03-01 |
| Not Yet Recruiting | Early Neutropenic Fever De-escalation of Antibiotics Study Hematologic Malignancy, Febrile Neutropenia, Antibiotic Stewardship | Phase 3 | 2024-03-01 |
| Withdrawn | Short-Term Endogenous Hydrogen Sulfide Upregulation For Vein Graft Disease Vascular Diseases, Surgery | N/A | 2024-03-01 |
| Active Not Recruiting | Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity Obesity, Weight Loss, Delayed Gastric Emptying Following Procedure | N/A | 2024-02-21 |
| Completed | Peer Support Intervention for Patients Undergoing Hematopoietic Stem Cell Transplantation Hematopoietic Neoplasms, Hematopoietic Malignancy | N/A | 2024-02-20 |
| Unknown | Drug Screening Using IMD in Bladder Cancer Muscle Invasive Bladder Urothelial Carcinoma | EARLY_Phase 1 | 2024-02-14 |
| Active Not Recruiting | Improving Sleep With a Digital Cognitive Behavioral Therapy for Insomnia Application Insomnia | N/A | 2024-02-13 |
| Completed | Multimodal, Task-Aware Movement Assessment and Control Using Functional Electrical Stimulation Post-stroke | — | 2024-02-07 |
| Active Not Recruiting | Pathophysiology of Dysautonomia and Postural Tachycardia Syndrome (POTS) in Post-viral Syndromes and COVID-19 POTS, POTS - Postural Orthostatic Tachycardia Syndrome, Dysautonomia | N/A | 2024-02-02 |
| Completed | Emergency Care at Home Emergency Medical Services, Emergency Department Visits | N/A | 2024-02-02 |
| Recruiting | Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT Advanced Prostate Cancer, Metastatic Prostate Cancer, Metastatic Prostate Neuroendocrine Carcinoma | Phase 1 | 2024-02-01 |
| Completed | Adjunctive Mindfulness During Opioid Tapering for patientS With Chronic Pain (The AMOS Study) Low Back Pain | N/A | 2024-02-01 |
| Recruiting | Acetazolamide as a Means to Mitigate Falling Ventilatory Drive and Drive-dependent OSA OSA | Phase 1 / Phase 2 | 2024-01-31 |
| Recruiting | Trazodone on OSA Endotypes Obstructive Sleep Apnea | Phase 1 / Phase 2 | 2024-01-01 |
| Active Not Recruiting | A Positive Psychology Based Intervention (PATH-C) for Caregivers of HSCT Survivors Hematologic Malignancy, Caregiver | N/A | 2024-01-01 |
| Completed | Smart Phone Delivered Cognitive Behavioral Therapy for Adults With Psoriasis and Co-Morbid Depression Symptoms Psoriasis, Depressive Symptoms | N/A | 2024-01-01 |
| Unknown | Low-Glycemic (LGI) Diet in Pregnant People With Epilepsy Epilepsy | N/A | 2023-12-15 |
| Recruiting | Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU Pulmonary Edema, Pneumonia, Atelectasis | N/A | 2023-12-12 |
| Recruiting | Detoxification of the Liver In PSC (Dolphin) Primary Sclerosing Cholangitis | Phase 2 | 2023-12-12 |
| Active Not Recruiting | Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndr Acute Respiratory Distress Syndrome, Sepsis | Phase 1 | 2023-12-06 |
| Recruiting | ED90 of Bupivacaine After Lidocaine Test Dose with DPE and EPL Labor Pain | Phase 4 | 2023-12-01 |
| Completed | Pharyngeal Muscle Control Mechanisms of Atomoxetine-plus-oxybutynin in Obstructive Sleep Apnea OSA | Phase 1 / Phase 2 | 2023-12-01 |
| Active Not Recruiting | Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susce Tuberculosis, Pulmonary, HIV | Phase 2 | 2023-11-24 |
| Recruiting | Pilot Testing a Novel Remotely Delivered Intensive Outpatient Program for Individuals With OUD Opioid Use Disorder, Serious Bacterial Infections | N/A | 2023-11-17 |
| Recruiting | Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatmen Overweight and Obesity | — | 2023-11-01 |
| Recruiting | Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers Salivary Gland Cancer, Adenoid Cystic Carcinoma of the Salivary Gland, Squamous Cell Carcinoma of Head and Neck | EARLY_Phase 1 | 2023-11-01 |
| Recruiting | Down Syndrome Obstructive Sleep Apnea Down Syndrome, Obstructive Sleep Apnea | Phase 2 | 2023-10-24 |
| Recruiting | Impact of Intensive Computerized Cognitive Training Acquired Brain Injury, Mild Cognitive Impairment, Mild Neurocognitive Disorder | N/A | 2023-10-01 |
| Completed | Long-term Effects of Blueberry Supplementation on Brain Health in Older Adults Cognitive Decline, Nutrition, Healthy, Brain Injuries | N/A | 2023-10-01 |
| Enrolling By Invitation | Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan Acute Suicidal Depression (ASD) | Phase 4 | 2023-10-01 |
| Completed | AGE SELF CARE: Promoting Healthy Aging Through a Group Visit Program Frailty, Aging, Frailty Syndrome | N/A | 2023-10-01 |
| Terminated | The Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD) REM Behavior Disorder | EARLY_Phase 1 | 2023-09-30 |
| Completed | Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers Regional Anesthesia Morbidity, Pain, Acute, Healthy | Phase 1 | 2023-09-28 |
| Recruiting | MCT for the Harvard/UCSF ROBIN Center Glioma, Childhood Brainstem, Neuroblastoma | N/A | 2023-09-19 |
| Not Yet Recruiting | Increasing Access to Definitive Treatment for Prostate Cancer Prostate Cancer | N/A | 2023-09-01 |
| Enrolling By Invitation | EpiFaith Resident Learning Curve Trial Epidural Analgesia, Epidural Analgesia for Labour and Delivery, Learning Curve | N/A | 2023-09-01 |
| Withdrawn | Pilot Study 1: Efficacy and Safety of Sublingual Dexmedetomidine (BXCL501) for the Treatment of Agitation in t Agitation, Schizophrenia, Schizoaffective Disorder | Phase 4 | 2023-09-01 |
| Withdrawn | Ketamine for the Treatment for Alcohol Use Disorder in the ED Alcohol Use Disorder | Phase 2 | 2023-09-01 |
| Recruiting | Mobile Intervention for Mental Health of Family Caregivers in Thailand Depressive Symptoms, Generalized Anxiety, or Psychological Stress | N/A | 2023-09-01 |
| Recruiting | Cerebellar TMS and Satiety in Prader-Willi Syndrome Prader-Willi Syndrome | N/A | 2023-09-01 |
| Active Not Recruiting | CP101 for the Treatment of Ulcerative Colitis Ulcerative Colitis | Phase 1 | 2023-09-01 |
| Recruiting | Ultrasound Therapy In Cardiac Amyloidosis Amyloidosis Cardiac | Phase 4 | 2023-08-31 |
| Recruiting | Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension Hypertension, Left Ventricular Hypertrophy | Phase 4 | 2023-08-25 |
| Recruiting | MRI Guided Prostate Biopsy Suspected Prostate Cancer | N/A | 2023-08-24 |
| Recruiting | Trial of Variable Dialysate Bicarbonate Peri-dialytic Cardiac Rhythms, Intradialytic Hypotension, Electrolyte Changes | N/A | 2023-08-24 |
| Completed | Refinement and Adaption of Reinforcement Learning to Personalize Behavioral Messaging for Healthy Habits Diabetes Mellitus, Type 2, Medication Adherence | N/A | 2023-08-23 |
| Completed | Social Norms, Messengers, and Processing Fluency to Increase Hypertension Medication Adherence Medication Adherence, Hypertension | N/A | 2023-08-18 |
| Active Not Recruiting | Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease Nasal Polyps, Asthma, Aspirin-Induced, Aspirin-Exacerbated Respiratory Disease | Phase 2 | 2023-08-01 |
| Completed | Evaluating Scaleup of an Adapted Breast Cancer Early Diagnosis Program in Rwanda Breast Cancer, Benign Breast Disease, Cervix Cancer | — | 2023-07-31 |
| Active Not Recruiting | Individualized Functional Connectivity Targeting in aiTBS for Depression Depressive Disorder, Major, Depression, Mood Disorders | Phase 2 | 2023-07-15 |
| Recruiting | Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin Pediatric HIV Infection, Tuberculosis Infection | Phase 1 | 2023-07-07 |
| Terminated | Deucravacitinib for the Treatment of Palmoplantar Pustulosis Palmoplantar Pustulosis | Phase 4 | 2023-07-01 |
| Recruiting | Rescue Pharmacotherapy for OSA Obstructive Sleep Apnea | Phase 1 / Phase 2 | 2023-07-01 |
| Unknown | Cesarean 123 Trial: Randomized Trial Comparing Single, Double and Triple Layer Uterine Closures During Cesarea Pregnancy Related | N/A | 2023-07-01 |
| Completed | SCI-Lynx: A Mobile Platform for Physical Activity Social Support for People With SCI Pilot Study Spinal Cord Injuries | N/A | 2023-06-14 |
| Completed | Electronic Strategies for Tailored Exercise to Prevent FallS Falls, Fall Injury, Exercise Self-Efficacy | N/A | 2023-06-08 |
| Recruiting | Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II Depression, Anxiety Disorders | N/A | 2023-06-07 |
| Withdrawn | Operator and Patient Acceptance of Radiofrequency Cautery of the Biopsy Track During Percutaneous Liver, Kidne Bleeding Disorder, Spleen Lesion, Liver Diseases | N/A | 2023-05-23 |
| Completed | COPILOT-HF: Cooperative Program for ImpLementation of Optimal Therapy in Heart Failure Heart Failure | Phase 4 | 2023-05-05 |
| Completed | Addressing Diffusion of Responsibility and Prescribing Burden to Improve Use of Diabetes Medications Diabetes, SGLT-2i and GLP-1RA Therapies, Diffusion of Responsibility | N/A | 2023-05-04 |
| Active Not Recruiting | Knee Arthroplasty Activity Trial Knee Osteoarthritis, Total Knee Replacement | N/A | 2023-04-27 |
| Recruiting | NAD Augmentation in Diabetes Kidney Disease Type2diabetes, Diabetic Kidney Disease | Phase 2 | 2023-04-13 |
| Recruiting | MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI Mesothelioma | Phase 2 | 2023-04-04 |
| Completed | MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction Erectile Dysfunction Following Radical Prostatectomy | N/A | 2023-04-01 |
| Recruiting | Dietary Intervention to Mitigate Adverse Consequences of Night Work Dietary Habits | N/A | 2023-03-29 |
| Unknown | Just in Time Cardio Pulmonary Resuscitation Trial Cardiopulmonary Arrest With Successful Resuscitation, Educational Problems | N/A | 2023-03-27 |
| Recruiting | The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Chronic Kidney Disease, Kidney Transplant, Coronary Microvascular Dysfunction (CMD) | — | 2023-03-10 |
| Not Yet Recruiting | Achieving Diagnostic Excellence Through Prevention and Teamwork Diagnostic Errors | N/A | 2023-03-01 |
| Completed | Project 1: Self-Triage by 2D Full-field Digital Mammography or Synthetic Images Breast Cancer Screening | N/A | 2023-03-01 |
| Recruiting | Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery D Peripheral Artery Disease, Peripheral Vascular Diseases, Dyslipidemias | N/A | 2023-03-01 |
| Unknown | Effect of Synapse Medicine Decision Support on Inpatient Pharmacist Efficacy and Efficiency Infections, Heart Diseases, Lung Diseases | N/A | 2023-03-01 |
| Active Not Recruiting | Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity Rheumatoid Arthritis, Palindromic Arthritis, Juvenile Rheumatoid Arthritis | N/A | 2023-03-01 |
| Unknown | Longitudinal Tracking of Patients Diagnosed With Neurodegenerative Movement Disorders Neurodegenerative Diseases, sca3, MSA - Multiple System Atrophy | — | 2023-03-01 |
| Completed | The Effects of a Virtual Yoga Program on Patients With Chronic Pain Chronic Pain | N/A | 2023-03-01 |
| Completed | Next Generation Ingestible Sensors for Medication Adherence Measurement HIV Infection, Adherence, Medication, Adherence, Treatment | Phase 3 | 2023-02-06 |
| Completed | Acetazolamide on REM OSA Obstructive Sleep Apnea | Phase 1 / Phase 2 | 2023-01-30 |
| Active Not Recruiting | A Hybrid Effectiveness/Implementation Trial of the International Guide for Monitoring Child Development Child Development | N/A | 2023-01-17 |
| Active Not Recruiting | Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure Blood Pressure | N/A | 2023-01-17 |
| Recruiting | PREventing Pain After Surgery Pain, Back, Spinal Stenosis, Disc Herniation | N/A | 2023-01-13 |
| Completed | Treating Insomnia and Improving Metabolic Health in Midlife Women With Insomnia Insomnia, Metabolic Health, Menopause | Phase 4 | 2023-01-06 |
| Completed | Molecular Imaging of Myocardial Fibrosis in Cardiac Amyloidosis Cardiac Amyloidosis | Phase 3 | 2023-01-03 |
| Completed | A Study on Hydroxocobalamin Given to Healthy Individual to Monitor Symptoms Hydroxocobalamin Adverse Reaction | Phase 1 | 2023-01-02 |
| Recruiting | Testing Effects of Melatonin on Uterine Contractions in Women Pregnant Women | N/A | 2023-01-01 |
| Unknown | Cell-based Therapy for the Treatment of Kidney Disease Kidney Diseases | EARLY_Phase 1 | 2023-01-01 |
| Not Yet Recruiting | Three-dimensional (3D) Printed Hemodialysis Vascular Model Hemodialysis Access Failure | N/A | 2023-01-01 |
| Unknown | Time-restricted Eating in Peri- and Postmenopausal Women Dyslipidemias, Obesity, Menopause | N/A | 2022-12-21 |
| Completed | Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants Genetic Predisposition to Disease, Hereditary Diseases | N/A | 2022-12-21 |
| Recruiting | SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder HIV Infections, Substance Use, Adherence, Medication | Phase 3 | 2022-12-20 |
| Recruiting | Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study Primary Aldosteronism, Hypertension | Phase 4 | 2022-12-15 |
| Unknown | First in Human Phase 1 Ascending Dose Study of PanChol in Healthy Volunteers Cholera, Cholera Vaccine Toxicity | Phase 1 | 2022-12-12 |
| Completed | Decision Support for Detection of Chronic Kidney Disease in Type II Diabetes Mellitus Chronic Kidney Diseases, Type2Diabetes | N/A | 2022-12-01 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Semaglutide v DPP4 Inhibitors Diabetes | — | 2022-11-30 |
| Completed | Implementation of a Combination Intervention for Sustainable Blood Pressure Control Hypertension | N/A | 2022-11-30 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Hypertension | — | 2022-11-30 |
| Completed | Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial) Pain, Opioid Use, Androgen Deficiency | Phase 2 | 2022-11-15 |
| Completed | NUDGE-EHR Replication Trial at Mass General Brigham Aging, Benzodiazepine Sedative Adverse Reaction, Anticholinergic Adverse Reaction | N/A | 2022-11-10 |
| Terminated | Study on Allopregnanolone and Depression in Perimenopausal Women Depression | Phase 4 | 2022-11-04 |
| Active Not Recruiting | Partnerships for Reducing Overweight and Obesity with Patient-Centered Strategies 2.0 Overweight, Obesity | N/A | 2022-11-03 |
| Completed | A Behavioral Science-Enhanced PHysician-led Remote Group Exercise InTervention for Women With Coronary Artery Coronary Artery Disease, Physical Inactivity, Sedentary Behavior | N/A | 2022-11-02 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Pentoxifylline Versus Cilostaz Peripheral Artery Disease | — | 2022-11-01 |
| Unknown | Preoperative Monoferric for Abdominal Surgery Anemia, Surgery | Phase 4 | 2022-11-01 |
| Recruiting | Microdevice In Ovarian, Fallopian Tube, And Peritoneal Cancer Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer | Phase 1 | 2022-11-01 |
| Enrolling By Invitation | Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes Infections, Heart Failure, COPD Exacerbation | N/A | 2022-11-01 |
| Active Not Recruiting | Monounsaturated Fatty Acid Supplementation for Overweight and Obese Individuals With Prediabetes PreDiabetes, Insulin Resistance, Overweight | N/A | 2022-11-01 |
| Completed | Endocannabinoids, Stress, Craving And Pain Effects Study Opioid Use Disorder | EARLY_Phase 1 | 2022-11-01 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Anastrozole vs Exemestane/Letr Breast Cancer | — | 2022-11-01 |
| Completed | Personalizing Preprocedural Sedation for Regional Anesthesia Catastrophizing Pain | EARLY_Phase 1 | 2022-10-22 |
| Recruiting | Menstrual-phase-dependent Differences in Response to Sleep Loss Sleep Deprivation | N/A | 2022-10-17 |
| Completed | Evaluation of the Impact of a Forward Viewing Scope at Time of ERCP Gastro-Intestinal Disorder | — | 2022-10-14 |
| Completed | Efficacy of the Quell Wearable Device for Chronic Overlapping Pain Conditions Chronic Pain, Adults 21 and Older, Multiple Chronic Overlapping Pain Conditions | N/A | 2022-10-14 |
| Recruiting | Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation Hemodialysis | Phase 2 | 2022-10-11 |
| Unknown | ED90 of Epidural Bupivacaine With Lidocaine for the Initiation of Labor Analgesia Labor Pain, Analgesia | Phase 4 | 2022-10-01 |
| Completed | Design and Usability Testing of a Tailored Intervention About Sleep and Sleep Disorders Among Transportation W Obstructive Sleep Apnea | N/A | 2022-10-01 |
| Completed | Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP Nasal Polyps, Aspirin-exacerbated Respiratory Disease | — | 2022-10-01 |
| Recruiting | PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes Type2Diabetes, ASCVD | Phase 4 | 2022-09-26 |
| Active Not Recruiting | Searching for Masses and Calcifications at the Same Time in Breast Cancer Screening Mammography, Breast Cancer, Radiology | N/A | 2022-09-01 |
| Active Not Recruiting | A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor Sepsis, Sepsis Bacterial, Lactate Blood Increase | N/A | 2022-08-01 |
| Unknown | Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms Light Exposure, Meal Timing | N/A | 2022-07-29 |
| Recruiting | Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile C. Difficile | N/A | 2022-07-25 |
| Completed | Self-Directed Positive Psychology Intervention for Newly Diagnosed Multiple Sclerosis Multiple Sclerosis | N/A | 2022-07-20 |
| Completed | Decreasing Unnecessary Antibiotics Prescribed for Possible Pneumonia Despite Normal Respiratory Rate and Oxyge Pneumonia | N/A | 2022-07-11 |
| Completed | Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part I Depression, Anxiety | N/A | 2022-07-06 |
| Withdrawn | Genicular Artery Embolization (GAE) for the Treatment of Chronic Post Knee Arthroplasty Pain Knee Pain Chronic, Knee Swelling Pain, Arterial Occlusion | N/A | 2022-07-01 |
| Completed | Digital Fall Prevention Study Fall | Phase 1 / Phase 2 | 2022-06-30 |
| Completed | Breaking Implicit Bias Habits: An Individuation Pilot Study In Rheumatology Systemic Lupus Erythematosus, Rheumatoid Arthritis, Inflammatory Arthritis | N/A | 2022-06-17 |
| Withdrawn | Can Simplified and More Detailed Instructions Affect Post-Operative Narcotic Consumption Opioid Use, Opioid Dependence, Knee Pain Chronic | Phase 4 | 2022-06-06 |
| Active Not Recruiting | AMP SCZ® Observational Study: PREDICT-DPACC Clinical High Risk, Psychosis, Remission | — | 2022-06-02 |
| Recruiting | Atomoxetine and DAW2022 on OSA Severity Obstructive Sleep Apnea | Phase 1 / Phase 2 | 2022-06-01 |
| Terminated | TEAMS-BP (The Enhancement of Social Networks to Augment Management of Stroke-Blood Pressure) Stroke, Acute Ischemic, Hypertension | N/A | 2022-05-31 |
| Enrolling By Invitation | Kinematics of Ewing Amputees Lower Extremity Amputation, Trans-Tibial Amputation, Traumatic Lower Extremity Amputation | — | 2022-05-17 |
| Unknown | Identifying Sleep Apnea Patients That Best Respond to Atomoxetine Plus Oxybutynin Therapy Obstructive Sleep Apnea | Phase 1 / Phase 2 | 2022-05-05 |
| Completed | Leveraging Electronic Health Record (EHR) Tools to Reduce Health Disparities for Patients With Uncontrolled Hy Hypertension, Blood Pressure | N/A | 2022-05-03 |
| Completed | Cook Balloon vs Dilapan-S for Outpatient Cervical Ripening Induced; Birth | N/A | 2022-05-01 |
| Completed | Cannabidiol on Reward- and Stress-related Neurocognitive Processes in Individuals With Opioid Use Disorder Opioid-use Disorder | Phase 2 | 2022-04-14 |
| Terminated | Observational Study of the Effect of Ozanimod on Fatigue in Multiple Sclerosis Patients Fatigue, Multiple Sclerosis | — | 2022-04-01 |
| Completed | Home-based Care and Hand Hygiene Interventions in Honduras Covid19 | N/A | 2022-03-31 |
| Completed | Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep Restrict Glucose Intolerance, Sleep Deprivation, Sleep | N/A | 2022-03-15 |
| Recruiting | The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk Stable Coronary Disease | Phase 4 | 2022-03-03 |
| Completed | Proof-of-Concept Trial of a Positive Psychology Intervention for Caregivers of Patients Undergoing HSCT Caregiver, Hematologic Malignancy | N/A | 2022-03-01 |
| Completed | Advance Care Planning in the Emergency Department Congestive Heart Failure, Metastatic Cancer, Chronic Kidney Disease Requiring Chronic Dialysis | N/A | 2022-03-01 |
| Completed | Home Hospital for Bariatric Sleeve Gastrectomy Bariatric Surgery Candidate, Bariatric Sleeve Gastrectomy, Home Hospital | N/A | 2022-02-23 |
| Completed | Use of Construal Level Theory to Inform Messaging to Increase Vaccination Against COVID-19 Covid19, Vaccine Refusal | N/A | 2022-02-18 |
| Active Not Recruiting | Birth Control to Improve Birth Spacing Contraception, Contraception Behavior, Knowledge, Attitudes, Practice | — | 2022-02-17 |
| Completed | Rural Hospital-Level Care at Home for Acutely Ill Adults Infections, Heart Failure, Chronic Obstructive Pulmonary Disease | N/A | 2022-02-16 |
| Completed | Sleep Well: Digital Insomnia Treatment Program For Physicians Sleep Disturbance, Insomnia, Stress, Psychological | N/A | 2022-02-04 |
| Active Not Recruiting | MR Antagonist and LSD1 Hypertension, Mineralocorticoid Excess | Phase 4 | 2022-02-03 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Montelukast vs Fluticasone Asthma | — | 2022-02-01 |
| Unknown | Prevalence of Sleep Apnea and Atrial Fibrillation Sleep Apnea, Atrial Fibrillation | — | 2022-02-01 |
| Recruiting | Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions Multiple Chronic Conditions, Adverse Event | N/A | 2022-02-01 |
| Withdrawn | Isolation of Cells From Biopsy Tissue to Aid in Kidney Repair Kidney Diseases, Endothelial Dysfunction | Phase 1 | 2022-01-21 |
| Recruiting | Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism Opioid Use, Pain, Hypogonadism, Male | Phase 2 | 2022-01-10 |
| Completed | The Effect of Mouth Closure on Airflow in OSA Hypopnea, Sleep | N/A | 2021-12-17 |
| Active Not Recruiting | Role of Dietary Habits in Efficacy of Bariatric Surgery - Study C Bariatric Surgery, Sleeve Gastrectomy, Obesity | N/A | 2021-12-07 |
| Withdrawn | Effect of Alemtuzumab on Microglial Activation Positron Emission Tomography (PET) in Multiple Sclerosis Multiple Sclerosis | Phase 1 / Phase 2 | 2021-12-01 |
| Active Not Recruiting | Sirtuin-NAD Activator in Alzheimer's Disease Alzheimer's Disease (Incl Subtypes), Dementia | Phase 1 / Phase 2 | 2021-12-01 |
| Completed | Ocrelizumab Access by Socio-Economic Status Multiple Sclerosis | — | 2021-11-18 |
| Completed | Nasal Protollin in Early Symptomatic Alzheimer's Disease Alzheimer Disease (AD) | Phase 1 | 2021-11-18 |
| Completed | Positive Psychology Intervention In HSCT Hematologic Malignancy, Hematopoietic/Lymphoid Cancer, Blood Cancer | N/A | 2021-11-17 |
| Completed | Validation of Circadian Biomarkers in Patients With Sleep Disorders Sleep Disorders, Circadian Rhythm, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder | — | 2021-11-02 |
| Completed | Digitally Assisted Recovery Coach Alcohol Use Disorder, Alcohol Withdrawal | N/A | 2021-11-01 |
| Unknown | Healthy Lifestyle Program: A Novel Group-based Training Obesity | N/A | 2021-11-01 |
| Recruiting | Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine Chronic Kidney Diseases | Phase 2 | 2021-11-01 |
| Completed | Personalizing Intervention to Reduce Clinical Inertia in the Treatment of Hypertension Hypertension | N/A | 2021-10-26 |
| Completed | Feasibility of Remote Home Support Coaches (SOCIAL Study) Malnutrition, Isolation, Depression | N/A | 2021-10-15 |
| Active Not Recruiting | Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density Lipoprotei Hyperlipemia, Mixed, ASCVD | N/A | 2021-10-08 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Amiloride vs Triamterene Hypertension | — | 2021-10-01 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Dihydropyridine Calcium Channe Hypertension | — | 2021-10-01 |
| Active Not Recruiting | Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases Brain Cancer, Brain Metastases, Melanoma | Phase 2 | 2021-09-15 |
| Recruiting | Assessing the Burden of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery Atrial Fibrillation, Cardiac Surgery | — | 2021-09-14 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - PDE5 Pulmonary Arterial Hypertension | — | 2021-09-01 |
| Active Not Recruiting | Feasibility of [11C]Acetate-PET in LAM and TSC Lymphangioleiomyomatosis, Tuberous Sclerosis Complex | Phase 1 / Phase 2 | 2021-08-30 |
| Completed | Prospective COVID-19 Cohort Study, Dominican Republic SARS-CoV-2 Infection, Covid19 | N/A | 2021-08-18 |
| Completed | Medication Adherence Patterns in Rheumatic Diseases: A Behavioral Trial Rheumatic Diseases, Gout, Adherence, Medication | N/A | 2021-08-02 |
| Active Not Recruiting | Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study Cardiovascular Events, Type2 Diabetes, Renal Disease | — | 2021-08-01 |
| Completed | People-Powered Medicine (PPM): Rheumatoid Arthritis Non-responders to Biologic Therapies (RANT) Rheumatoid Arthritis | — | 2021-07-06 |
| Unknown | Prevention of Opioid Use Disorder After Surgery Opioid-use Disorder, Opioid Dependence, Opioid Use | N/A | 2021-07-02 |
| Recruiting | Detection of Small Fiber Neuropathy Using Skin Properties Small Fiber Neuropathy | — | 2021-07-01 |
| Unknown | BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes Diabetes Mellitus, Type 2 | — | 2021-07-01 |
| Completed | Prediction of the SEPRA Diabetes Trial in Healthcare Claims Data Diabetes Mellitus, Type 2 | — | 2021-07-01 |
| Completed | PROJECT 2 EXAMPLE: Feedback X Prevalence Using Dermatology Stimuli Decision Making | N/A | 2021-06-22 |
| Completed | Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts Seemingly Healthy, Genetic Predisposition to Disease | N/A | 2021-06-09 |
| Withdrawn | Parasternal Subpectoral Plane Blocks for Cardiac Surgery Via a Midline Sternotomy Pain, Postoperative | N/A | 2021-06-01 |
| Recruiting | Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis, Obesity | — | 2021-06-01 |
| Completed | COVID-19 Vaccine Response in Treated MS Patients Multiple Sclerosis, Healthy | — | 2021-06-01 |
| Terminated | Biomarkers for Circadian Timing in Healthy Adults Sleep Wake Disorders, Sleep Disorders, Circadian Rhythm, Sleep Disorders, Intrinsic | — | 2021-06-01 |
| Withdrawn | ION-682884 in Patients With TTR Amyloid Cardiomyopathy Transthyretin Amyloid Cardiopathy | Phase 2 | 2021-06-01 |
| Active Not Recruiting | Role of Dietary Habits in Efficacy of Bariatric Surgery - Study B Bariatric Surgery, Sleeve Gastrectomy, Obesity | — | 2021-05-25 |
| Completed | Shared Decision-making on Medical Tests and Care Cascades Health Knowledge, Attitudes, Practice, Health Care Utilization | N/A | 2021-05-24 |
| Active Not Recruiting | COcoa Supplement and Multivitamin Outcomes Study: Effects on Falls and Physical Performance Fall, Physical Performance, Fracture | N/A | 2021-05-15 |
| Active Not Recruiting | A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG) Non-alcoholic Steatohepatitis (NASH), Endoscopic Sleeve Gastroplasty, Non-alcoholic Fatty Liver Disease (NAFLD) | N/A | 2021-05-06 |
| Completed | Prediction of the COBRRA AF Anticoagulant Trial in Healthcare Claims Data Atrial Fibrillation | — | 2021-05-03 |
| Withdrawn | Maintenance Versus Reduction of Immunosuppression for Renal Transplant Patients Hospitalized With COVID-19 Dis COVID, Kidney Transplant; Complications, Immunosuppression | Phase 2 / Phase 3 | 2021-05-03 |
| Completed | Prediction of the COBRRA VTE Anticoagulant Trial in Healthcare Claims Data Venous Thromboembolism, Pulmonary Embolism, DVT | — | 2021-05-03 |
| Completed | Levari Exp.20: 2D - Partial Feedback Form Perception, Color Perception, Decision Making | N/A | 2021-05-01 |
| Recruiting | CONFIRM: Magnetic Resonance Guided Radiation Therapy Gastric Cancer, Invasive Breast Cancer, in Situ Breast Cancer | N/A | 2021-05-01 |
| Completed | Beyond COVID-19: Supporting Resilience With a Trauma-informed Music Composition Program Problems Related to Life-Management Difficulty | N/A | 2021-04-22 |
| Active Not Recruiting | Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water Body Weight | N/A | 2021-04-22 |
| Unknown | Pre-Insertion Ultrasound for Lateral-Position Spinal in Cesarean Delivery Cesarean Section, Spinal Anesthesia, Lumbar Ultrasound | N/A | 2021-04-22 |
| Unknown | Comparing Human and Computer-based Quantification of Airway Stenosis From Bronchoscopic Images Airway Obstruction | N/A | 2021-04-16 |
| Active Not Recruiting | Deferoxamine for the Prevention of Cardiac Surgery-Associated Acute Kidney Injury Acute Kidney Injury | Phase 2 | 2021-04-13 |
| Completed | MAnnitol for Blood Pressure Stability in HemoDialysis (MAP-HD) Hemodialysis Complication, Hemodynamic Instability | Phase 2 / Phase 3 | 2021-04-06 |
| Withdrawn | Randomized Trial of Supercharged End-to-Side Anterior Interosseous Nerve Transfer for Severe Cubital Tunnel Sy Cubital Tunnel Syndrome, Ulnar Nerve Compression, Ulnar Nerve Palsy | N/A | 2021-04-05 |
| Withdrawn | SystemIc iNflammation and Microvascular diSease PreventIon in psoRiatic diseasE Psoriasis, Psoriatic Arthritis, Cardiovascular Risk Factor | Phase 4 | 2021-04-01 |
| Completed | Cognitive Behavioral Therapy (CBT) Pain Prevention Intervention for Women Undergoing Surgery Back Pain, Cognitive Behavioral Therapy, Surgery | N/A | 2021-04-01 |
| Unknown | Prospective Monitoring of Non-Vitamin K Oral Anticoagulants in Older Adults With Atrial Fibrillation and Frail Atrial Fibrillation, Frailty, Anticoagulant-induced Bleeding | — | 2021-03-30 |
| Completed | Novel Application of Simulation for Providers to Overcome Decisional Gaps in High-risk Prescribing Medication Administered in Error, Antipsychotics and Neuroleptics Toxicity | N/A | 2021-03-29 |
| Completed | Improving Detection and Early Action for HPV-positive Oropharynx Cancer HPV Positive Oropharyngeal Squamous Cell Carcinoma | N/A | 2021-03-24 |
| Completed | Diabetes Remote Intervention to improVe Use of Evidence-based Medications Cardiovascular Diseases, Diabetes | Phase 4 | 2021-03-22 |
| Completed | Prediction of Patient Deterioration Using Machine Learning Infection, Heart Failure, Chronic Obstructive Pulmonary Disease | — | 2021-03-20 |
| Withdrawn | Serum Potassium Prediction Using Machine Learning and Single-lead ECG Infection, Heart Failure, Chronic Obstructive Pulmonary Disease | — | 2021-03-20 |
| Withdrawn | Prediction of Expected Length of Hospital Stay Using Machine Learning Infection, Heart Failure, Chronic Obstructive Pulmonary Disease | — | 2021-03-20 |
| Unknown | Potassium Binder in CKD Patients (With Hyperkalemia) (DiPo Trial) Chronic Kidney Diseases, Hyperkalemia | Phase 1 | 2021-03-15 |
| Completed | Safety of TofAcitinib in Routine Care Patients With Rheumatoid Arthritis (STAR-RA)-Cancer Endpoints Rheumatoid Arthritis | — | 2021-03-10 |
| Unknown | Effect of Lighting Supplementation on Daytime Cognition Non-visual Effects of Light | N/A | 2021-03-01 |
| Completed | Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thro Deep Vein Thrombosis, Pulmonary Embolism, Venous Thromboembolism | Phase 4 | 2021-03-01 |
| Completed | Electronic Tools to Increase Recognition and Improve Primary Care Management for Hypertension in Chronic Kidne Chronic Kidney Diseases, Hypertension | N/A | 2021-02-26 |
| Completed | Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques Labor Pain, Analgesia | Phase 4 | 2021-02-25 |
| Completed | Safety of TofAcitinib in Routine Care Patients With Rheumatoid Arthritis (STAR-RA)- Cardiovascular Endpoints Rheumatoid Arthritis | — | 2021-02-22 |
| Completed | Rural Home Hospital: Proof of Concept Infection, Heart Failure, Chronic Obstructive Pulmonary Disease | N/A | 2021-02-18 |
| Unknown | Multimodal, Task-Aware Movement Assessment and Control: Clinic to the Home Frailty | — | 2021-02-17 |
| Completed | Lipid Management in Renal Transplant Recipients Using Evolocumab. Hyperlipidemias | Phase 4 | 2021-02-17 |
| Unknown | Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia Gestational Trophoblastic Neoplasia, Molar Pregnancy, Gestational Trophoblastic Tumor, Non-Metastatic | Phase 3 | 2021-02-11 |
| Completed | Reinforcement Learning in Diabetes Mellitus Trial Diabetes Mellitus, Type 2, Medication Adherence | N/A | 2021-02-04 |
| Completed | Symptom-specific TMS Targets for Depression and Anxiety Depression, Anxiety, Major Depressive Disorder | Phase 2 | 2021-02-03 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Salbutamol vs Long-acting Mus Chronic Obstructive Pulmonary Disease | — | 2021-02-01 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines - (DREAM) Probenecid vs Allopurinol Gout | — | 2021-02-01 |
| Completed | A Nurse-led, Advance Care Planning Intervention in the Emergency Department Emergency Department, Motivational Interviewing, Advance Care Planning | N/A | 2021-01-29 |
| Terminated | Breath Biomarkers for Sleep Loss and Circadian Timing Shift-Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Sleep Disorders, Circadian Rhythm | — | 2021-01-28 |
| Unknown | Virtual White Boards for Patient Satisfaction Satisfaction, Patient, Covid19, Emergencies | N/A | 2021-01-25 |
| Completed | Comparison of Vasodilator Response of Inhaled Epoprostenol and Inhaled Nitric Oxide Pulmonary Hypertension | Phase 4 | 2021-01-15 |
| Unknown | Prospective Monitoring of Angiotensin Receptor Neprilysin Inhibitor in Older Adults With Heart Failure and Fra Heart Failure, Systolic, Frailty | — | 2021-01-14 |
| Withdrawn | Use of Transcranial Magnetic Stimulation to Reduce Craving for Individuals With Opioid Use Disorder Taking Bup Opioid-use Disorder | N/A | 2021-01-01 |
| Withdrawn | Testosterone Effects on Pelvic Floor Muscles Urinary Incontinence, Menopause | Phase 3 | 2021-01-01 |
| Withdrawn | PRETELL: PREvention of TELomere-related Complications After Lung Transplant Short Telomere Length, Lung Transplant | Phase 1 / Phase 2 | 2021-01-01 |
| Recruiting | Defibrotide for the Treatment of Severe COVID-19 Covid19 | Phase 2 | 2021-01-01 |
| Completed | Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients Multiple System Atrophy, Multiple System Atrophy, Cerebellar Variant, Multiple System Atrophy, Parkinson Variant (Disorder) | EARLY_Phase 1 | 2020-12-30 |
| Completed | Vitamin D for COVID-19 Trial COVID-19 | Phase 3 | 2020-12-28 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Methotrexate vs Hydroxychloro Rheumatoid Arthritis | — | 2020-12-23 |
| Completed | Mindful Meditation for Epidural Catheter Placement Anxiety, Pain | N/A | 2020-12-21 |
| Unknown | Ravulizumab and COVID-19 Covid19, Thrombotic Microangiopathies, Acute Kidney Injury | Phase 3 | 2020-12-18 |
| Completed | Replication of the DAPA-CKD (Chronic Kidney Disease) Trial in Healthcare Claims Data Chronic Kidney Disease | — | 2020-12-13 |
| Completed | Replication of the IMPACT COPD Trial in Healthcare Claims Data COPD | — | 2020-12-13 |
| Completed | EMG Biofeedback Treatment for Chronic Low Back Pain, Cancer Pain and Migraines Chronic Low-back Pain, Mastectomy, Lumpectomy | N/A | 2020-12-03 |
| Completed | Pharmacological Intervention for Symptomatic Mild Sleep Disordered Breathing Sleep Disordered Breathing | Phase 2 | 2020-12-02 |
| Withdrawn | Daylight Photodynamic Therapy for the Treatment of Actinic Keratoses in the Northeast United States Actinic Keratosis, Non-melanoma Skin Cancer | N/A | 2020-12-01 |
| Completed | The Impact of Sublingual Sufentanil on Postoperative Pain and Analgesic Requirements in Spine Surgery Patients Spine Fusion, Pain, Postoperative, Opioid Use | Phase 4 | 2020-12-01 |
| Completed | Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in Obesity Metabolic Syndrome, Hypertension, Overweight and Obesity | Phase 4 | 2020-12-01 |
| Unknown | Standing Tall (Yima Nkqo) HIV | Phase 2 | 2020-11-25 |
| Active Not Recruiting | A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation Neoplasms, Hiv, Cervical Cancer | Phase 2 | 2020-11-18 |
| Unknown | DAW2020 on OSA Endotypic Traits Obstructive Sleep Apnea (OSA) | Phase 1 / Phase 2 | 2020-11-15 |
| Unknown | Shared Decision Aid for Post-Total Knee Arthroplasty Opioid Prescribing Knee Arthroplasty, Total, Analgesia, Opioid Use, Unspecified | N/A | 2020-11-02 |
| Unknown | Pilot Study of Financial Incentives for YMSM for HIV Testing and PrEP HIV | N/A | 2020-11-01 |
| Completed | Replication of the P04334 Asthma Trial in Healthcare Claims Data Asthma | — | 2020-10-29 |
| Completed | Replication of the VERO Osteoporosis Trial in Healthcare Claims Data Osteoporosis | — | 2020-10-29 |
| Completed | Replication of the D58 Asthma Trial in Healthcare Claims Data Asthma | — | 2020-10-29 |
| Completed | ACT for High Frequency Migraine; A Virtual Mindfulness Intervention Migraine | N/A | 2020-10-25 |
| Recruiting | Jump: MR Simulation For Radiation Therapy Master Protocol Prostate Cancer, Recurrent Adenocarcinoma, Liver Cancer | N/A | 2020-10-14 |
| Completed | Optimizing Electronic Health Record Prompts With Behavioral Economics to Improve Prescribing for Older Adults Aging, Benzodiazepine Sedative Adverse Reaction, Anticholinergic Adverse Reaction | N/A | 2020-10-13 |
| Completed | Replication of the EINSTEIN-PE Anticoagulant Trial in Healthcare Claims Data Pulmonary Embolism | — | 2020-10-10 |
| Completed | Replication of the ISAR-REACT 5 Antiplatelet Trial in Healthcare Claims Data Acute Coronary Syndrome | — | 2020-10-10 |
| Completed | Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy Volunteers Compartment Syndrome of Leg, Healthy | Phase 1 | 2020-09-29 |
| Completed | Replication of the RECOVER-II Anticoagulant Trial in Healthcare Claims Data Venous Thromboembolism | — | 2020-09-22 |
| Completed | Replication of the RECORD1 Anticoagulant Trial in Healthcare Claims Data Deep Vein Thrombosis, Pulmonary Embolus | — | 2020-09-22 |
| Completed | Replication of the EINSTEIN-DVT Anticoagulant Trial in Healthcare Claims Data Venous Thromboembolism | — | 2020-09-22 |
| Completed | Replication of the INSPIRE Trial in Healthcare Claims Data Chronic Obstructive Pulmonary Disease | — | 2020-09-22 |
| Completed | Replication of the HORIZON Pivotal Fracture Trial in Healthcare Claims Data Osteoporosis | — | 2020-09-22 |
| Completed | Replication of the AMPLIFY Anticoagulant Trial in Healthcare Claims Data Venous Thromboembolism | — | 2020-09-22 |
| Completed | Replication of the PARADIGM-HF Heart Failure Trial in Healthcare Claims Data. Heart Failure | — | 2020-09-22 |
| Completed | Replication of the POET-COPD Trial in Healthcare Claims Data Chronic Obstructive Pulmonary Disease | — | 2020-09-22 |
| Completed | 9-month Study to Assess the Efficacy of Ofatumumab on Microglia in Patients With Relapsing Forms of Multiple S Relapsing Multiple Sclerosis | Phase 3 | 2020-09-21 |
| Active Not Recruiting | Serial Brain MRI in Hospitalized Preterm Infants Preterm Birth Complication | N/A | 2020-09-14 |
| Completed | Phenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep Apnea Sleep Apnea | N/A | 2020-09-10 |
| Withdrawn | Evaluation of the Efficacy of Sodium Oxybate (Xyrem®) in Treatment of Post-traumatic Narcolepsy and Post-traum Hypersomnia, Narcolepsy, Traumatic Brain Injury | EARLY_Phase 1 | 2020-09-01 |
| Unknown | Deceased Uterine Transplant in Absolute Uterine Infertility (AUIF) Infertility of Uterine Origin | N/A | 2020-09-01 |
| Completed | Replication of the ROCKET-AF Anticoagulant Trial in Healthcare Claims Data Atrial Fibrillation | — | 2020-09-01 |
| Completed | Replication of the ARISTOTLE Anticoagulant Trial in Healthcare Claims Data Atrial Fibrillation | — | 2020-09-01 |
| Unknown | The Effects of Tildrakizumab in Treatment of Bullous Pemphigoid Pemphigoid, Bullous | EARLY_Phase 1 | 2020-09-01 |
| Completed | Calcium Channel Blockade in Primary Aldosteronism Primary Aldosteronism, Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral) | Phase 2 | 2020-09-01 |
| Completed | A Pilot Study Examining Diet in Primary Sclerosing Cholangitis Primary Sclerosing Cholangitis | N/A | 2020-08-28 |
| Terminated | Sleep and Circadian Treatments for Shift Workers Shift-Work Sleep Disorder, Shift-Work Related Sleep Disturbance | N/A | 2020-08-20 |
| Completed | Optimizing the Safety of Inter-Hospital Transfer Inpatient Facililty Diagnoses | N/A | 2020-08-17 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tocilizumab vs Abatacept Rheumatoid Arthritis | — | 2020-08-17 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tofacitinib vs Abatacept Rheumatoid Arthritis | — | 2020-08-17 |
| Completed | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - TNFi vs Abatacept Rheumatoid Arthritis | — | 2020-08-17 |
| Completed | Operational Trial of Dayzz App Sleep Initiation and Maintenance Disorders | N/A | 2020-08-12 |
| Completed | Cannabidiol Use to Reduce Cravings in Individuals With Opioid Use Disorder on Buprenorphine Opioid-use Disorder | Phase 2 | 2020-08-03 |
| Unknown | Phase I/II Trial of Povidone-iodine (PVP-I) Nasal Swab For Preventing COVID-19 Spread in Healthy Subjects Covid19, Povidone Iodine Adverse Reaction | Phase 1 / Phase 2 | 2020-08-01 |
| Unknown | Transparent Elastomeric Respirator for Aerosol-based Protection Personal Protective Equipment | N/A | 2020-07-25 |
| Unknown | COMT on Aspirin Platelets Effects (CAPE) Cardiovascular Diseases | Phase 4 | 2020-07-10 |
| Completed | Weight Loss Before Total Joint Arthroplasty Using A Remote Dietitian and Mobile App Arthroplasties, Replacement, Weight Loss, Nutrition | N/A | 2020-07-01 |
| Completed | Promoting Earlier Detection of Breast Cancer in Rwanda: Scaleup in the National Health Care System Breast Cancer, Benign Breast Disease | — | 2020-07-01 |
| Unknown | Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer Prostate Cancer, Radical Prostatectomy | Phase 1 | 2020-06-22 |
| Withdrawn | Lung Irradiation for COVID-19 Pneumonia SARS-CoV 2 | N/A | 2020-06-19 |
| Withdrawn | Preventing Cardiac Surgery Readmission With Patient Activity Tracking Technology Cardiac Surgery, Enhanced Recovery | N/A | 2020-06-01 |
| Active Not Recruiting | INTREPId (INTermediate Risk Erection PreservatIon Trial) Prostate Cancer | Phase 2 | 2020-06-01 |
| Unknown | Partnership in Implementation Science for Geriatric Mental Health (PRISM) Behavioral and Psychological Symptoms of Dementia (BPSD) | N/A | 2020-06-01 |
| Completed | Integrating Chiropractic Care and Mind-Body Training for the Treatment of Nonspecific Chronic Neck Pain Neck Pain, Nurse-Patient Relations | N/A | 2020-05-07 |
| Unknown | Revisiting the Mechanism of the Anti-inflammatory Effect of Colchicine Colchicine Mechanism of Action | Phase 1 | 2020-05-06 |
| Terminated | Evaluation of SARS-CoV-2 (COVID-19) Antibody-containing Plasma thErapy COVID, Infectious Disease | Phase 3 | 2020-04-30 |
| Completed | Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19 Coronavirus Infection | — | 2020-04-01 |
| Completed | COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboem Covid19, Thrombosis Embolism, DVT | — | 2020-03-24 |
| Unknown | Role of Microglial Activation and Norepinephrine Transporter Abnormalities in Pathogenesis of MS-related Fatig Multiple Sclerosis | Phase 1 / Phase 2 | 2020-03-12 |
| Unknown | Immunogenicity of Quadrivalent Meningococcal Conjugate Vaccine in Frequent Platelets Donors Preventive Immunization; Meningitis | Phase 4 | 2020-03-12 |
| Completed | Acceptability of Telehealth Triage Using Robotic Systems in COVID-19 COVID-19, Telemedicine, Robotics | — | 2020-03-10 |
| Withdrawn | Enhancing Nutrition and Antenatal Infection Treatment for Maternal and Child Health in Ethiopia Low Birthweight, Preterm Birth, Maternal; Malnutrition, Affecting Fetus | Phase 4 | 2020-03-01 |
| Withdrawn | Initiating Substance Use Disorder Treatment for Hospitalized Alcohol Use Disorder Patients Alcohol Use Disorder | N/A | 2020-03-01 |
| Completed | COVID-19 Risk Stratification Coronavirus, Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere | — | 2020-03-01 |
| Active Not Recruiting | 18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy Bladder Cancer, Urothelial Carcinoma | EARLY_Phase 1 | 2020-02-26 |
| Recruiting | AMI Construction in Lower Extremity Residual Limbs Amputation | N/A | 2020-02-24 |
| Completed | A Study of Bedside Versus Hallway Rounding Education, Medical | N/A | 2020-02-01 |
| Active Not Recruiting | Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development Preterm Birth, Breast Milk Expression, Nutrition Disorder, Infant | N/A | 2020-01-31 |
| Completed | Comparing Nifedipine and Enalapril in Medical Resources Used in the Postpartum Period Hypertension in Pregnancy, Preeclampsia Severe, Gestational Hypertension | Phase 4 | 2020-01-24 |
| Completed | The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Chronic Fatigue Syndrome, Myalgic Encephalomyelitis | Phase 2 | 2020-01-14 |
| Completed | Sleep Bootcamp: A Pilot Tele-Sleep Program for Former National Football League (NFL) Players Sleep, Insomnia, Pain | N/A | 2020-01-14 |
| Completed | ICON-2: FMT and Bezlotoxumab Compared to FMT and Placebo for Patients With IBD and CDI Inflammatory Bowel Diseases, Clostridium Difficile Infection | Phase 2 | 2020-01-01 |
| Withdrawn | Hyaluronidase in Treating Oral Microstomia in Patients With Sclerosing Skin Disease Microstomia, Scleroderma, CREST Syndrome | EARLY_Phase 1 | 2020-01-01 |