NCT07315997

The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: Brigham and Women's Hospital · Academic / Other
• Sex: All
• Age: 35 Years – 79 Years
• Healthy volunteers: Not accepted

Summary

Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier.

Detailed description

The objective of this study is to test the utility of high sensitivity cardiac troponin (hs-cTn) and coronary artery calcium (CAC) in risk stratifying patients with rheumatoid arthritis (RA) who may benefit from lipid lowering therapy. The population of interest are individuals who would not otherwise be recommended for therapy based on general population risk calculators for heart disease risk.

Conditions

• Rheumatoid Arthritis (RA
• Atherosclerotic Cardiovascular Disease (ASCVD)

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	high sensitivity cardiac troponin	Blood measurement of high sensitivity cardiac troponin

Timeline

• Start date: 2024-09-04
• Primary completion: 2028-03-04
• Completion: 2028-03-04
• First posted: 2026-01-05
• Last updated: 2026-01-05

Locations

1 site across 1 country: United States