NCT05381532

Menstrual-phase-dependent Differences in Response to Sleep Loss

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Brigham and Women's Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This study is designed to assess how healthy premenopausal women respond to different patterns of sleep loss at different times in the menstrual cycle.

Detailed description

During a 1.5-week inpatient laboratory protocol, participants will undergo one of two parallel sleep conditions during either the follicular or luteal phase of the menstrual cycle (4 study arms total). Subjects will be randomly assigned to each study arm. During their time in the laboratory, biological samples (e.g., blood) will be collected for assessment of sex steroid hormones and other analyses. Sleep quantity and quality will be monitored and responses on neurobehavioral tests and surveys will be monitored for differences across conditions.

Conditions

• Sleep Deprivation

Interventions

Type	Name	Description
BEHAVIORAL	Controlled sleep	Duration and timing of sleep will be assigned and monitored in a controlled laboratory environment.

Timeline

• Start date: 2022-10-17
• Primary completion: 2026-03-31
• Completion: 2026-03-31
• First posted: 2022-05-19
• Last updated: 2025-09-19

Locations

1 site across 1 country: United States