Trials / Not Yet Recruiting
Not Yet RecruitingNCT06854211
Impacts of Opioids on Respiratory Drive During Sleep
Mechanisms of Opioid-induced Respiratory Depression (OIRD) During Sleep
- Status
- Not Yet Recruiting
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 26 (estimated)
- Sponsor
- Brigham and Women's Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
The investigators are studying the impact that opioids have on breathing during sleep in healthy participants and those diagnosed with obstructive sleep apnea.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Morphine p.o. | Morphine 50mg PO will be given on sleep study night. |
| DRUG | Placebo | Placebo will be given on the sleep study night. |
Timeline
- Start date
- 2026-07-01
- Primary completion
- 2027-01-01
- Completion
- 2027-01-31
- First posted
- 2025-03-03
- Last updated
- 2026-01-29
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT06854211. Inclusion in this directory is not an endorsement.