NCT05800990

Eating to Adjust the Timing System

Do Dietary Patterns Influence Your Weight Management and Circadian Rhythms?

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Brigham and Women's Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to test the effects of dietary composition on the rhythms of food intake, appetite regulation, and rhythms of energy expenditure. Participants will: complete 2 field-based dietary interventions be provided with standard meals record daily food intake in a real-time manner complete 2 inpatient stays be provided with standard meals have frequent blood draws provide urine, saliva, and stool samples

Detailed description

Obesity is an ongoing epidemic and a serious public health problem. Recent insights into the involvement of the circadian system (i.e., an internal biological rhythm) in energy expenditure and appetite control offer a new perspective to understand the relationship between dietary composition and weight management. Particularly, dietary composition may impact whole-body physiology in part through changes in the circadian system. The study protocol is designed to test the effects of dietary composition, on the rhythms of food intake and appetite regulation, and rhythms of energy expenditure. This study seeks to understand the relationship between dietary composition and weight control in order to lay the groundwork for evidence-based dietary intervention to combat obesity.

Conditions

• Dietary Intervention

Interventions

Type	Name	Description
BEHAVIORAL	dietary intervention	Research participants will be assigned to two dietary conditions.

Timeline

• Start date: 2024-11-08
• Primary completion: 2027-08-31
• Completion: 2027-08-31
• First posted: 2023-04-06
• Last updated: 2025-09-29

Locations

1 site across 1 country: United States