NCT04868526

Dietary Intervention to Mitigate Adverse Consequences of Night Work

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Brigham and Women's Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to test whether our dietary intervention can prevent or lessen the negative health effects of night shift work in healthy participants. Participants will: * complete 2 inpatient stays * be provided with identical meals * have frequent blood draws * provide urine, saliva, stool and rectal swab samples

Detailed description

Shift work increases the risk for diabetes possibly due to the adverse metabolic effects of circadian misalignment. As shift work is not foreseen to disappear, the development of individually-targeted therapies for metabolic health in these vulnerable shift workers is urgently needed. This research will determine whether our dietary intervention can mitigate the adverse metabolic effects of circadian misalignment, which may help in the design of evidence-based dietary interventions to improve the metabolic health in shift workers.

Conditions

• Dietary Habits

Interventions

Type	Name	Description
BEHAVIORAL	dietary intervention	Research participants will be assigned to two dietary conditions.

Timeline

• Start date: 2023-03-29
• Primary completion: 2026-09-01
• Completion: 2026-09-01
• First posted: 2021-05-03
• Last updated: 2025-12-05

Locations

1 site across 1 country: United States