NCT04898738

Prospective COVID-19 Cohort Study, Dominican Republic

Prospective COVID-19 Cohort Study to Assess the Epidemiology, Transmission and Control of SARS-CoV-2 in the Dominican Republic

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,043 (actual)
• Sponsor: Brigham and Women's Hospital · Academic / Other
• Sex: All
• Age: 2 Years
• Healthy volunteers: Accepted

Summary

This project will build on an existing CDC funded cooperative agreement in the Dominican Republic with the Brigham and Women's Hospital (2018-2023) that includes (i) prospective COVID-19 and AFI surveillance at two health facilities and (ii) a nationally representative cross-sectional community-based serological survey of approximately 7,000 healthy adults and children targeting SARS-CoV-2 and other AFI pathogens to be conducted between April and June 2021. This linked study will establish a nested cohort of 2,000 participants enrolled in the national serological survey and prospectively monitor them for COVID-19 symptoms, conduct serial serological testing, implement molecular surveillance for SARS-CoV-2 and sequencing for variants of concern, implement and evaluate WASH mitigation measures, and monitor uptake and perceptions of COVID-19 vaccines.

Conditions

• SARS-CoV-2 Infection
• Covid19

Interventions

Type	Name	Description
OTHER	Alcohol based hand sanitizer	Provision of ABHS to randomly selected households

Timeline

• Start date: 2021-08-18
• Primary completion: 2022-11-22
• Completion: 2023-02-10
• First posted: 2021-05-24
• Last updated: 2025-11-17

Locations

1 site across 1 country: Dominican Republic