NCT04962438

Effects of Anti-VEGF Targeted Drugs on Patients' Blood Pressure and Endothelial Function

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Peking University Third Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Explore the effects of anti-VEGF targeted drugs on blood pressure and endothelial function in cancer patients.

Detailed description

Thirty tumor patients with anti-VEGF drugs were selected. Demographic information and clinical information of all patients were collected before chemotherapy. Ambulatory blood pressure monitoring and endothelial function measurement (PWV, EndoPAT) were performed. Ambulatory blood pressure and PWV were reviewed at 2 weeks and 1 month. And EndoPAT, to evaluate the effects of anti-VEGF drugs on blood pressure and endothelial function in cancer patients.

Conditions

• Cardiac Toxicity
• VEGF
• Endothelial Dysfunction

Interventions

Type	Name	Description
DRUG	Anti-VEGF	Anti-tumor drugs targeting the vascular endothelial growth factor (VEGF) signaling pathway

Timeline

• Start date: 2019-07-05
• Primary completion: 2021-12-01
• Completion: 2021-12-30
• First posted: 2021-07-15
• Last updated: 2021-07-15

Locations

1 site across 1 country: China