NCT05798182

Ultrasound Markers of Systemic Inflammation

Ultrasound in the Intensive Care Unit and Measurable Indicators of Systemic Inflammation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 61 (actual)
• Sponsor: Osijek University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study was to measure whether the flow rate through the brachial artery and inflammatory markers were associated with the development of tissue edema in the surgical intensive care unit patients.

Detailed description

The study was performed using a ultrasound machine with linear probe settings at 50 mm depth and 40 decibel \[dB\] gain that did not change during the study. The probe was placed on vascular ultrasound measurement. The diameter of the brachial artery in the middle of the upper arm and the flow rate through the artery was measured on postoperative days 1 and 2. The presence of the edema was measured above the 3rd metacarpal bone as the distance from the skin surface to the periosteum. An average of three assessments was shown. Patient's age, body mass index (BMI), type of admission, white blood cells (WBC), C-reactive protein (CRP), and procalcitonin (PCT) were also registered.

Conditions

• Inflammation Process
• Endothelial Dysfunction
• Vasomotor Arterial Disorder
• Vascular Dilation
• Swelling; Hand

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Ultrasound measurement	Study was conducted with Mindray T7 ultrasound machine using linear probe. Vascular ultrasound mode was used with settings depth of 50 mm and gain of 40 dB during the entire study period. The diameter and flow velocity of the brachial artery and wrist edema of the fist were measured within 24 hours of admission and the following day.

Timeline

• Start date: 2020-12-01
• Primary completion: 2021-12-30
• Completion: 2021-12-30
• First posted: 2023-04-04
• Last updated: 2023-04-04

Locations

1 site across 1 country: Croatia