NCT03934398

Be-HealthY: Behavioral Risk Factors for Poor Vascular Health in Youth

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 41 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 22 Years
• Healthy volunteers: Not accepted

Summary

The investigators aim to determine the association of dietary intake on cardiovascular disease risk factors among children with overweight and obesity who are being evaluated for elevated blood pressure. The investigators will also investigate for predictors of vascular function and determine if predictors vary by level of sodium intake.

Detailed description

This research is being done to determine if the food or salt eaten can cause arteries to be stiffer and/or not work as well and if it can impact blood pressure over a 24-hour period of time. The investigators also want to determine if there are any risk factors or blood tests that can predict how stiff arteries are or how well arteries function. The investigators hope that the information from this study will help the investigators prevent blood pressure-related cardiovascular disease in children. This knowledge could help shape future guidelines on how to best prevent and treat high blood pressure and heart disease in children.

Conditions

• Prehypertension
• Hypertension
• Overweight and Obesity
• Elevated Blood Pressure
• Endothelial Dysfunction
• Vascular Stiffness
• Sleep

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cardiovascular Assessments	Participants will undergo the following cardiovascular assessments: 24-hour blood pressure monitoring, arterial stiffness measurements, endothelial function measurements.
DIAGNOSTIC_TEST	Actigraphy	Participants will wear an actigraph device for 7 days to measure participant's activity and sleep.
DIAGNOSTIC_TEST	Laboratory assessments	Participants will provide blood and urine samples for laboratory assessments.
DIAGNOSTIC_TEST	Emotional/Behavioral Assessments	Participants and parents will fill out questionnaires for emotional/behavioral assessments

Timeline

• Start date: 2019-04-10
• Primary completion: 2022-05-31
• Completion: 2022-05-31
• First posted: 2019-05-01
• Last updated: 2022-06-22

Locations

1 site across 1 country: United States