NCT05185934

The Effect of Dietary Intervation on Endothelial Glycocalyx in COVID-19 Patients.

The Effect of Dietary Glycocalyx Precursor Supplementation on Endothelial Function, on Markers of Vascular Function and on Cardiac Performance in Patients With COVID-19 Infection.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: University of Athens · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The food supplement Endocalyx is considered to support the endothelial glycocalyx integrity by supplying sulfated polysaccharides, anti-oxidant enzymes and additional substrates for glycocalyx synthesis. The investigators will study the effect of Endocalyx on endothelial, vascular and left ventricular myocardial function in patients with COVID-19 infection.

Detailed description

Sixty patients who have been hospitalized due to COVID-19 infection will be randomized to receive food supplement Endocalyx (4 capsules per day) (n=30) or placebo (n=30) for 4 consecutive months.

Conditions

• COVID-19
• Endothelial Dysfunction

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Food supplement Endocalyx	Patients with COVID-19 infection will be randomized to receive food supplement Endocalyx for 4 months.
DIETARY_SUPPLEMENT	Placebo	Patients with COVID-19 infection will be randomized to receive placebo for 4 months.

Timeline

• Start date: 2022-06-01
• Primary completion: 2023-11-01
• Completion: 2024-01-30
• First posted: 2022-01-11
• Last updated: 2023-05-16

Locations

1 site across 1 country: Greece