NCT03171441

Microvascular Reactivity in Prepubertal Children

Microcirculation, Adiposity, and Traditional and Emerging Cardiovascular Risk Factors in Prepubertal Children

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 98 (actual)
• Sponsor: Rio de Janeiro State University · Academic / Other
• Sex: All
• Age: 5 Years – 10 Years
• Healthy volunteers: Accepted

Summary

This is a cross-sectional study aimed to investigate microvascular reactivity in prepubertal children according to adiposity status.

Detailed description

The investigators aimed to investigate microvascular reactivity in prepubertal and to compare these data in different groups according to adiposity status. Firstly, The investigators recruited only children from 5 to 10 years at prepubertal status. After excluding those with exclusion criteria and the acceptance (from their parents) to participate in the study, a blood sample was collected and an appointment at BioVasc lab was programmed. At this day, participants were subject to nail fold videocapillaroscopy. A method used to investigate microvascular reactivity by a non-invasive mean. After this, participants children were followed to the outpatient's care unit to continue follow-up.

Conditions

• Child, Only
• Obesity
• Endothelial Dysfunction

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	nailfold videocapillaroscopy	non-invasive nailfold videocapillaroscopy
DIAGNOSTIC_TEST	inflammatory biomarkers	blood sample collection to asses leptin and C-reactive protein

Timeline

• Start date: 2013-01-01
• Primary completion: 2014-02-01
• Completion: 2014-04-01
• First posted: 2017-05-31
• Last updated: 2017-05-31