Trials / Unknown
UnknownNCT05691426
Assessment of the Effect of Non-surgical Periodontal Treatment on Endothelial Function- a Prospective Study
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (estimated)
- Sponsor
- University of Sharjah · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
An association between periodontitis and endothelial dysfunction has been reported, suggesting that periodontitis presents an inflammatory burden to the cardiovascular system, that might lead to AVD. The study aims aim to assess whether non-surgical periodontal therapy enhances endothelial function in periodontitis patients using a non-invasive diagnostic device to assess endothelial function through PWA and the assessment of levels of salivary Endothelin-1, in a population of people in the UAE.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Assessment of pulse wave amplitude (PWA) | Assessment of pulse wave amplitude (PWA) through peripheral arterial tonometry (PAT) using the device EndoPAT (Itamar Medical) |
| DIAGNOSTIC_TEST | Salivary Nitric Oxide | assessment the levels of salivary Nitric Oxide using a Nitric Oxide colorimetric detection kit, |
Timeline
- Start date
- 2022-10-01
- Primary completion
- 2023-12-01
- Completion
- 2024-06-01
- First posted
- 2023-01-20
- Last updated
- 2023-01-25
Locations
1 site across 1 country: United Arab Emirates
Source: ClinicalTrials.gov record NCT05691426. Inclusion in this directory is not an endorsement.