Trials / Conditions / Insulin Resistance

Insulin Resistance

1,028 registered clinical trials studyying Insulin Resistance — 88 currently recruiting.

Status	Trial	Sponsor	Phase
Withdrawn	Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance NCT04062890	University of Arizona	Phase 2
Not Yet Recruiting	Human Models of Selective Insulin Resistance: Pancreatic Clamp NCT06558422	Columbia University	Phase 1
Not Yet Recruiting	Exercise, Insulin Resistance, and Chronic Pain in Postmenopausal Women. NCT07407699	São Paulo State University	N/A
Not Yet Recruiting	Determining Cell- and Spatially-distinct Skeletal Muscle Transcriptional Aberrations in Insulin Resistance NCT07516509	AdventHealth Translational Research Institute	—
Recruiting	Effect of Insulin Lowering on Lipogenesis NCT07403604	Columbia University	Phase 1
Not Yet Recruiting	Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance NCT07494084	Washington State University	Phase 4
Not Yet Recruiting	Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity NCT05713799	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Phase 2
Recruiting	The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV NCT07226128	Indiana University	N/A
Recruiting	Impact of a Probiotic Supplementation With Lifestyle Modification on Liver Steatosis, Fibrosis, and Metabolic NCT07400367	Fu Jen Catholic University Hospital	N/A
Not Yet Recruiting	Empagliflozin Adjunctive Therapy in Bipolar Depression NCT07472920	University of Sao Paulo	N/A
Recruiting	MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity NCT07505745	Hudson Biotech	Phase 2
Not Yet Recruiting	Insomnia and Insulin Resistance NCT07333586	University of Missouri-Columbia	N/A
Recruiting	Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive NCT07220694	SF Research Institute, Inc.	N/A
Not Yet Recruiting	SCUBE Proteins in Polycystic Ovary Syndrome (IPSOS) NCT07396402	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	N/A
Completed	Serum Betatrophin Levels in Normal-Weight and Overweight Adolescents With PCOS NCT07480993	Ankara City Hospital Bilkent	—
Recruiting	Glucose Profiles in Women With Polycystic Ovary Syndrome NCT07483723	Centre Hospitalier Universitaire, Amiens	N/A
Not Yet Recruiting	Effects of Sweetener Consumption on Risk Factors for Heart Disease in Prediabetic Subjects NCT07377097	Charite University, Berlin, Germany	N/A
Recruiting	Effects of Ketone Bodies on Insulin Sensitivity NCT07359625	University of Aarhus	N/A
Recruiting	ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence NCT07102797	Massachusetts General Hospital	N/A
Recruiting	Impact of Starch Digestibility on Glycemic Variability and Control, Cardiometabolic and Inflammatory Profiles, NCT07408479	Mondelēz International, Inc.	N/A
Recruiting	New Mechanisms of Obesity NCT06768827	Yale University	N/A
Not Yet Recruiting	Efficacy of NOSHINtrial in Diabetic Patients NCT06205030	Kerman Medical University	Phase 4
Not Yet Recruiting	Effect of Add-on SGLT2i, TZD, or Combination Therapy in Type 2 Diabetes Patients on DPP4 Inhibitors NCT07108985	Yonsei University	Phase 4
Active Not Recruiting	Machine Learning-Based Prediction of Insulin Resistance in Psoriasis Patients Emphasizing Interpretability NCT07321288	Chinese PLA General Hospital	—
Recruiting	Human Skeletal Muscle Response to 5 Days of Bedrest in Young Adults NCT07178353	Queen's University	N/A
Recruiting	Fastomics: Metabolic and Therapeutic Effects of Prolonged Fasting NCT07216989	University of Minnesota	—
Recruiting	A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents NCT07223151	Nana Gletsu Miller	N/A
Recruiting	Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI) NCT07297290	University Of Nigeria Teaching Hospital	Phase 3
Recruiting	Effects of Cranberry on Gut and Metabolic Health NCT07460856	Laval University	N/A
Recruiting	Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial NCT06138821	Pichamol Jirapinyo, MD, MPH	N/A
Active Not Recruiting	Effects of Chestnuts on Postprandial Glycaemic Response NCT06960967	Monash University	N/A
Completed	Cistanche Deserticola Extract Combined With Aerobic Exercise Improves Body Composition, Insulin Resistance and NCT07486557	Beijing Sport University	N/A
Active Not Recruiting	Ice Cream Enriched With Cimarrón Bean Extrudate and Cardiovascular Risk in Adults NCT07076563	University of Talca	N/A
Completed	Acute Postprandial Effects of Functional Ice Cream With Cimarrón Bean Extrudate in Adults NCT07053267	University of Talca	N/A
Recruiting	Photoacoustic/Ultrasound Imaging of Brown Adipose Tissue Activity NCT07327684	Peking Union Medical College Hospital	N/A
Completed	Metformin vs Inositol vs Diet vs Combination Therapy in PCOS NCT07380841	Islamabad Medical and Dental College	N/A
Recruiting	Metabolic Effects of Linoleic Acid-Rich Oil Compared to a Blend Oil in Adults With Insulin Resistance NCT07287514	Pontificia Universidad Catolica de Chile	N/A
Enrolling By Invitation	Hepatic Elastography-Enhanced Lifestyle Modification in MASLD NCT06826807	Mahidol University	N/A
Recruiting	Effect of Tele-exercise on Cardiorespiratory Fitness in Paediatrics NCT06770660	KK Women's and Children's Hospital	N/A
Not Yet Recruiting	Impact of Chromium Supplementation on Glucido-lipidic Metabolism, Oxidative Stress and Inflammatory State in P NCT06860087	University of Kasdi Merbah	Phase 1 / Phase 2
Active Not Recruiting	Study to Evaluate the Efficacy of an Avocado Dietary Supplement NCT07354308	SP Nutraceuticals Inc.	N/A
Not Yet Recruiting	The Effect of Ketogenic-caloric Restricted Diet on Metabolic Endotoxemia in Prediabetic Obese Adults NCT06911879	University of Jordan	N/A
Not Yet Recruiting	The Effect of Time Restricted Eating on Glycemic and Proinflammatory Biomarkers Among Prediabetic Obese Jordan NCT06911918	University of Jordan	N/A
Completed	Effects of Sourdough Fermentation Duration and Acid Development on Postprandial Blood Glucose in Prediabetic A NCT06925451	Arizona State University	N/A
Recruiting	Role of Aging and Individual Variation in Exercise Training Responsiveness NCT06471569	Duke University	N/A
Recruiting	Efficacy and Safety of Vitamin D Supplementation in Pediatric Patients with Obesity NCT06847373	Coordinación de Investigación en Salud, Mexico	N/A
Recruiting	A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults NCT06820658	Mayo Clinic	—
Active Not Recruiting	Effect of a Multidomain Intervention Plus Turmeric on the Prevention of Cognitive Decline in People Over 55 Ye NCT07284316	Instituto Mexicano del Seguro Social	Phase 2 / Phase 3
Withdrawn	Effect of Very Low Carbohydrate Diet on Glycemic, Metabolic, Glycated and Inflammatory Markers in Gestational NCT05305352	Khyber Medical University Peshawar	N/A
Not Yet Recruiting	NUTRITIONAL INTERVENTION STUDY to EVALUATE the EFFECT of ACHETA DOMESTICUS POWDER CONSUMPTION on GLUCOSE HOMEO NCT06622616	María Isabel Espinosa	N/A
Completed	Efficacy of Chromium Picolinate in Reducing Acanthosis Nigricans Severity in Adolescents With Insulin Resistan NCT07371169	Uruk University	N/A
Withdrawn	Nut Intake At Night: Effect on Postprandial Glycaemia NCT04965896	Monash University	N/A
Not Yet Recruiting	Insulin Resistance in Egyptian Patients With Multiple Sclerosis NCT06017726	Assiut University	—
Completed	Triglyceride-Glucose and TGI-BMI Indices Compared With HOMA-IR NCT07260201	Hisar Intercontinental Hospital	—
Withdrawn	Night Time Walking to Improve Glycaemic Control in Healthy Adults NCT04958317	Monash University	N/A
Active Not Recruiting	EFFECTS OF OLEUROPEIN ON BLOOD PARAMETERS AND INFLAMMATORY MARKERS IN ADULTS WITH METABOLIC SYNDROME NCT06673914	Atlas University	N/A
Recruiting	Diazoxide Suppression Test P&F Study NCT06606327	Columbia University	Phase 1
Recruiting	Alternative Physical Activity Strategies for Breast Cancer Survivors NCT06633380	University of Toronto	N/A
Not Yet Recruiting	Insulin Resistance and Resisted Exercise Post Burn NCT06654908	Cairo University	N/A
Recruiting	Electro-Acupuncture for Obese Patients With Insulin Resistance NCT06609200	Nanyang Technological University	N/A
Recruiting	Graded Insulin Suppression Test P&F NCT06592261	Columbia University	Phase 1
Completed	Mangosteen Supplement as Adjuvant Therapy With Sitagliptin/Metformin in Iraqi Patients With Type 2 Diabetes NCT07172269	Mais Qais Hbeeb	N/A
Active Not Recruiting	MRI Assessment of Pancreatic Fat Changes and Islet Function Recovery After Bariatric Surgery in Obese Patients NCT07464223	yu li，MD	—
Completed	Relation Between Insulinoresistance and Neutrophile to Lymphocyte Ratio in Cardiac Surgery. NCT06945536	Centre Hospitalier Universitaire de Besancon	—
Recruiting	Neuromuscular Electrical Stimulation: A Novel Treatment for Improving Metabolism NCT06722391	University of Texas, El Paso	N/A
Enrolling By Invitation	The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD. NCT06334666	Mahidol University	N/A
Active Not Recruiting	The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes NCT06159543	Loma Linda University	N/A
Not Yet Recruiting	Inulin in Burn-induced Insulin Resistance NCT05532488	University of Belgrade	N/A
Withdrawn	Dexamethasone/Pancreatic Clamp P&F NCT06126354	Columbia University	Phase 1
Recruiting	Effect of GLP1 Receptor Agonist on Brain Insulin Responsiveness NCT06487832	University Hospital Tuebingen	N/A
Completed	Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Co NCT06479434	Aga Khan University	N/A
Recruiting	Insulin Resistance and Coronary Microvascular Dysfunction in Patients with Myocardial Ischemia and Non-obstruc NCT06597851	Azienda Ospedaliera Universitaria Integrata Verona	N/A
Recruiting	Effects of Antipsychotics on Brain Insulin Action in Females NCT06251635	Centre for Addiction and Mental Health	N/A
Not Yet Recruiting	Insulin Resistance in Relation to Hyperthyroidism and Hypothyroidism NCT06399796	Assiut University	—
Completed	Modulating Energy Density in Time-Restricted Eating NCT06259435	Pennington Biomedical Research Center	N/A
Not Yet Recruiting	High Intensity Interval Versus Focused Ultrasound on Insulin Resistance in Diabetics With Abdominal Obesity NCT06376955	Badr University	N/A
Recruiting	Characteristics of Papez Loop Neural Network in T2DM （Type 2 Diabetes Mellitus） NCT06912321	Nanjing First Hospital, Nanjing Medical University	—
Completed	Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Pr NCT06426017	Khyber Medical University Peshawar	N/A
Completed	Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes NCT06401876	Mayo Clinic	—
Active Not Recruiting	Combining Physical Activity and Sedentary Interventions to Improve Cardiometabolic Health NCT07363499	Hasselt University	N/A
Recruiting	Human Models of Selective Insulin Resistance: Alpelisib, Part I NCT06354088	Columbia University	Phase 1
Completed	Does Co-administration of Lactate to an Oral Glucose Tolerance Test Lower the Glucose Response? NCT06265337	University of Aarhus	N/A
Not Yet Recruiting	Association Between Triglycerides Glucose Ratio With HOMA -IR as Indicators of Insulin Resistance in Obese Adu NCT06358989	Assiut University	—
Active Not Recruiting	Probiotics and Insulin Resistance in Obese Asthmatics NCT05949255	University of Alabama at Birmingham	N/A
Completed	An Integrative Study of the Role of Microbiome, Metabolome, Transcriptome and Chronobiology in the Context of NCT06783218	Clinica Universidad de Navarra, Universidad de Navarra	—
Completed	Effect of Intravenous 5% Dextrose Infusion During Recovery from Anesthesia on the Quality of Early Postoperati NCT06319144	Weifang Medical University	N/A
Completed	Association of Vitamin D Status With Metabolic Markers in Adolescents With Polycystic Ovary Syndrome NCT06970821	Bagcilar Training and Research Hospital	—
Completed	De-tensioning Patch, in Subjects With Type 1 Diabetes and Lipohypertrophy NCT06025513	Neodyne Biosciences, Inc.	N/A
Terminated	Role of Insulin Action in Psoriasis Pathogenesis NCT06242847	Columbia University	—
Withdrawn	Role of Endothelin-1 Modulating Insulin-stimulated Blood Flow and Sympathetic Nervous System Activity in Obesi NCT05518422	University of Missouri-Columbia	EARLY_Phase 1
Recruiting	Fasting Insulin and HOMA-IR by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis NCT05950282	Lilli Health	—
Active Not Recruiting	Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testost NCT06998238	University of Missouri-Columbia	N/A
Unknown	Study of Visceral Fat in type2diabetic Patients and Its Relation to Microvascular Complications NCT06112197	Sohag University	—
Recruiting	Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling NCT06129110	University of Colorado, Denver	N/A
Completed	Impact of Preoperative Oral Carbohydrate Loading on Insulin Resistance in Adult Cardiac Surgery Patients NCT07212153	Rifdhani Fakhrudin Nur	N/A
Recruiting	Effects of Insulin Resistance in Non-diabetic Acute Coronary Syndrome Patients NCT06163768	University of Medicine and Pharmacy at Ho Chi Minh City	N/A
Active Not Recruiting	Glucose Evaluation Through Continuous Glucose Monitors in Polycystic Ovary Syndrome NCT06050265	University of California, San Francisco	N/A
Unknown	Effect of Life Style Modification and Metformin on Hypothyroidism With Insulin Resistance NCT06096454	Assiut University	Phase 4
Recruiting	Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Diff NCT05743868	Yale University	N/A
Recruiting	The Acute T-Rex (Timing of Resistance Exercise) Study NCT06366399	University of Utah	N/A
Recruiting	Exercise Training on Brain Insulin Responsiveness NCT06039787	University Hospital Tuebingen	N/A
Recruiting	Effect of Timed-Restricted Eating on Metabolic Health NCT06061042	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	N/A
Completed	Effect of Dietary Protein on the Regulation of Exosome microRNA Expression in Patients With Insulin Resistance NCT05318898	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	N/A
Completed	Explore the Relationship Between Heart Rate Variability, Body Mass Index, Inflammation, and Insulin Resistance NCT05949710	National Tainan Junior College of Nursing	N/A
Recruiting	Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD NCT04984226	University of California, Davis	Phase 2
Recruiting	Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents NCT06007404	University of Michigan	—
Completed	Pancreatic Clamp in NAFLD NCT05724134	Columbia University	Phase 1
Active Not Recruiting	Effects of Phytosterol Supplementation on Liver Function and Inflammatory Status in Patients with Nonalcoholic NCT06697977	University of Jordan	N/A
Completed	Glycemic Effect of Diazoxide in NAFLD NCT05729282	Columbia University	Phase 1
Completed	Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity NCT06242535	Hoskinson Health and Wellness Clinic	EARLY_Phase 1
Recruiting	Metabolic Adaptations to Weight Loss With and Without Exercise NCT05806801	University of Michigan	N/A
Completed	Development of a Novel Algorithm for Real-Time Bedside Assessment of Insulin Resistance in Critically Ill Pati NCT07385391	Chinese Medical Association	—
Unknown	Effect of Radiofrequency on Insulin Resistence in Obese Post Menopansal Women NCT05818293	Cairo University	N/A
Completed	The Effect of Oral Whey Consumption on Insulin Resistance, Cortisol, Crp, Albumin Level and Healing Quality Be NCT06307782	TC Erciyes University	N/A
Recruiting	Small Extracellular Vesicles and Insulin Action NCT05933707	Washington University School of Medicine	N/A
Recruiting	Obesity, Insulin Resistance, and PASC: Persistent SARS-CoV-2 NCT05833217	Stanford University	N/A
Completed	Tolerability, Acceptance, and Utility of Intermittent CGM Use in Youth With Prediabetes NCT05505565	University of Alabama at Birmingham	N/A
Recruiting	Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes NCT05543083	Colorado State University	N/A
Completed	Effects of Sucralose in Gut Intestinal Microbiota and Postprandial GLP-1 NCT06094894	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	N/A
Unknown	Promoting Immune Health by Intermittent Fasting: a Pilot Study NCT05898360	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	N/A
Active Not Recruiting	Signos DM2 Empowerment Study (SIGNOS-CGM-EMPOWER-201-2022) NCT05874635	Signos Inc	N/A
Completed	Acute Exercise on Brain Insulin Sensitivity NCT05853913	Rutgers, The State University of New Jersey	N/A
Unknown	Prevalence of IR in Overweight and Obese Adolescents NCT05810883	Assiut University	—
Completed	Effect of Alpelisib in Healthy Volunteers NCT05733455	Columbia University	Phase 1
Completed	ACUTE EFFECT OF CONSUMPTION OF GROUND OR WHOLE FLAXSEEDS ON BLOOD GLUCOSE IN PEOPLE WITH TYPE 2 DIABETES NCT06912542	Universidade Francisca	N/A
Completed	Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic NCT05776862	University of Miami	Phase 2
Active Not Recruiting	Everolimus Aging Study NCT05835999	University of Wisconsin, Madison	Phase 2
Recruiting	Intermittent Fasting Versus Carbohydrate Drinks Before Surgery NCT05760339	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	N/A
Active Not Recruiting	A Study Evaluating Daily Oral Doses of TLC-3595 in Participants With Insulin Resistance NCT05665751	OrsoBio, Inc	Phase 2
Recruiting	Effects of Oral Glutamine Supplementation on Insulin Resistance and Functional Intestinal Disorders in Obese P NCT04883515	University Hospital, Rouen	N/A
Recruiting	The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults NCT05912348	University of New Hampshire	N/A
Unknown	BaRiatric Surgery AnD FRUctose Handeling In Obese subjecTs NCT05717595	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	N/A
Completed	Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Type 2 Diabetes Patients (DELI_Diab Study) NCT05770076	Bogomolets National Medical University	N/A
Unknown	The Study Aims to Investigate the Effects of Oral Inositols on Insulin-resistance in Children With Obesity. NCT05701813	Azienda Ospedaliera Universitaria Integrata Verona	N/A
Completed	Effect of HIIT Vs Moderate Intensity Aerobic Exercise on Insulin Resistance in Type 2 DM NCT05902546	Badr University	N/A
Completed	Brain Clock and Insulin Resistance NCT05314855	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	—
Recruiting	FMT in Obesity: RYGB vs. LEAN vs. Autologous FMT NCT06268990	Wiebke Kristin Fenske	N/A
Completed	Bone Properties Following Exercise Induced Changes in Insulin Sensitivity in People With Type 2 Diabetes NCT06668090	Aarhus University Hospital	N/A
Unknown	Triglyceride-Glucose Index In Heart Failure Patients In Sohag University Hospital NCT05663632	Sohag University	—
Recruiting	Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical Exercise NCT06959043	Maria Elizabeth Rossi da Silva	N/A
Completed	Effect of Whole-body Vibration on Insulin Resistance in Obese Postmenopausal Women. NCT05961020	October 6 University	N/A
Active Not Recruiting	Monounsaturated Fatty Acid Supplementation for Overweight and Obese Individuals With Prediabetes NCT05560971	Brigham and Women's Hospital	N/A
Unknown	Metabolic Effects of Whey Protein Supplementation After Fasting in Volunteers NCT05656339	Federal University of Mato Grosso	N/A
Unknown	Effect of Metformin, Dapagliflozin, Combination of Metformin and Pioglitazone in Patients With Type 2 Diabetes NCT05591235	Nanjing First Hospital, Nanjing Medical University	Phase 3
Completed	Sleep and IR in Transgender Adolescents NCT05489159	Duke University	—
Completed	Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation NCT05404711	Mary Ellen Vajravelu, MD	N/A
Completed	Using a Complex Carbohydrate Mixture to Steer Fermentation and Improve Metabolism in Adults With Overweight an NCT05354245	Maastricht University Medical Center	N/A
Completed	The Dose-response Effects of High Intensity Functional Training on Metabolic Syndrome Risk Factors NCT05001126	Gary Van Guilder	N/A
Completed	Combining HIIT and n-3 PUFA to Reduce Inflammation and Improve Metabolic Health NCT05295719	Texas Tech University	N/A
Withdrawn	Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer NCT04741204	Woman's	Phase 4
Unknown	Pre-operative Carbohydrates in Diabetic Patients Undergoing CABG NCT05540249	China National Center for Cardiovascular Diseases	N/A
Active Not Recruiting	Understanding Dose Related Effects of Strawberry NCT06173765	Clinical Nutrition Research Center, Illinois Institute of Technology	N/A
Unknown	Impact of Preoperative Oral Branched-chain Amino Acids on Reducing Postoperative Insulin Resistance. NCT05494658	Sun Peng	N/A
Unknown	Dissecting the IMpact of 11-OXygenated and Classic Androgens on Skeletal Muscle Insulin Sensitivity (DIMOXIS) NCT05263557	Royal College of Surgeons, Ireland	N/A
Recruiting	Improving Glycemic Control With Electrical Stimulation NCT03947697	University of Texas, El Paso	N/A
Not Yet Recruiting	The Inland Norway Healthy Life Center Study NCT05450406	Inland Norway University of Applied Sciences	N/A
Completed	Efficacy and Safety of D-chiro-inositol in Obese Patients NCT05348941	Lo.Li.Pharma s.r.l	N/A
Completed	Link Between the Peripheral Mononuclear Cells' Capacity to Induce Insulin Resistance and Hyperinsulinemia NCT05329337	Centre Hospitalier Universitaire de Nīmes	N/A
Terminated	Bile Acids in Acute Insulin Resistance NCT05571670	Columbia University	—
Unknown	KurCoSmart Effects on People With Type 2 DM NCT05407467	Universitas Sebelas Maret	Phase 1 / Phase 2
Recruiting	Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D) NCT05277558	Washington University School of Medicine	—
Completed	Mindfulness-Based Intervention for Depression and Insulin Resistance in Adolescents NCT04992299	Colorado State University	N/A
Completed	High-fat Meal Challenge in Pediatrics NCT05230433	Dartmouth-Hitchcock Medical Center	N/A
Completed	Impact of Gestational Diabetes on Childhood Obesity NCT07069296	Tokat Gaziosmanpasa University	N/A
Withdrawn	Heat Therapy in Patients With Type 2 Diabetes Mellitus NCT05237219	University of Pecs	N/A
Completed	Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (PEG)-BHD1028 NCT06563115	EncuraGen, Inc	Phase 1
Active Not Recruiting	Effects of Intermittent Fasting on Insulin Resistance, Cardiac Metabolism, and Cerebral Perfusion NCT05181267	University of Aarhus	N/A
Withdrawn	Combining HIIT and n-3 PUFA Supplementation to Reduce Inflammation and Improve Metabolic Health (HIIT&PUFA) NCT05297383	Texas Tech University	N/A
Recruiting	Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms NCT05307367	University of Copenhagen	N/A
Completed	Effect of Insulin Resistance on Branched Chain Amino Acid Metabolism. NCT04886973	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	N/A
Completed	Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome NCT05215223	Cairo University	N/A
Completed	Sucralose and Glucose Metabolism in Young Healthy Adults NCT07194772	University of Ottawa	N/A
Completed	Impact of Sorghum Rice on Beta-Cell Function and Insulin Resistance in Prediabetes NCT07298304	Dr. Soetomo General Hospital	N/A
Completed	The Influence of Daily Honey Consumption on IR in Obese Women With IR NCT05427799	University of Jordan	N/A
Active Not Recruiting	Plasma Trimethylamine N-oxide Elevation Induced by L-carnitine Supplementation and Insulin Resistance NCT05251207	Poznan University of Physical Education	N/A
Active Not Recruiting	Energy Metabolism and Acute Effects of Protein Diets in Metabolically Obese Normal Weight Individuals NCT06802341	Singapore Institute of Food and Biotechnology Innovation	N/A
Withdrawn	Effects of Amino Acid Supplementation on Liver Lipid Content and Protein Metabolism in Obese Children NCT02337894	Arkansas Children's Hospital Research Institute	N/A
Recruiting	Dietary Strategies for Remission of Type 2 Diabetes NCT04943926	University of Bergen	N/A
Completed	Subclinical Impairment of Cardiovascular System in Patients With Psoriasis NCT05957120	University Medical Centre Ljubljana	—
Terminated	High-intensity Interval Training for Obese Individuals NCT04075799	University of New Mexico	N/A
Completed	The Effects of Yogurt on Gut Microbiome and Metabolism in H. Pylori. NCT05374980	Taichung Veterans General Hospital	N/A
Recruiting	Mitochondrial Substrate Utilization in the Diabetic Human Heart NCT05958706	Heinrich-Heine University, Duesseldorf	—
Withdrawn	Insulin Resistance and Androgen Deprivation Therapy NCT04995978	St. Louis University	Phase 2
Suspended	Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation NCT05153395	University of Missouri-Columbia	EARLY_Phase 1
Completed	Behavioral Economics for Activity Motivation in Adolescents (BEAM) NCT04874415	University of Pittsburgh	N/A
Completed	Effect of Dietary SFA and Fructose on Hepatic Insulin Sensitivity NCT05017675	Maastricht University Medical Center	N/A
Completed	Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity NCT05017571	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Phase 2
Active Not Recruiting	Enhancing Brain Health by TDCS in Persons with Overweight and Obesity NCT05228067	University Hospital Tuebingen	N/A
Completed	Personalized Fiber and Insulin Sensitivity NCT05378295	Maastricht University Medical Center	N/A
Unknown	LNK in Polycystic Ovary Syndrome With Insulin Resistance NCT05146063	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	—
Recruiting	Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance NCT04578652	University of Alberta	Phase 3
Completed	Metabolic Effects of Plant-based Diet NCT05351853	Koç University	N/A
Completed	TREating Pediatric Obesity NCT05124847	Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud	N/A
Recruiting	Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohor NCT06167135	Semmelweis University	—
Completed	Myoinositol Treatment and Asprosin Levels in PCOS NCT05951309	Near East University, Turkey	N/A
Recruiting	Effect of Daily Erythritol Versus Sucrose Intake Over 5 Weeks on Glucose Tolerance in Adolescents NCT04966299	University Hospital, Basel, Switzerland	N/A
Suspended	Mechanisms of Insulin Resistance and Exercise in South Asians NCT04007926	University of Glasgow	N/A
Withdrawn	Pioglitazone and Insulin Resistance in ADT NCT05098327	State University of New York at Buffalo	Phase 3
Unknown	Determination of Insulin-stimulated Hepatic Glucose Uptake by PET-CT Measurements NCT04938544	Maastricht University Medical Center	—
Completed	T1D, Metabolic Syndrome and Insulin Resistance NCT05503303	Universidad Juárez Autónoma de Tabasco	—
Active Not Recruiting	MR-based Characterization of Bone Marrow in Its Relevance to Skeletal Disease in Patients With Diabetes NCT04950283	University Hospital Tuebingen	—
Completed	Adherence and Tolerability of Four Very Low-Calorie Ketogenic Diet Approaches in Adults With Obesity or Compli NCT07389122	University of Bologna	—
Recruiting	Mitigating the Pro-inflammatory Phenotype of Obesity NCT04934228	University of Kansas Medical Center	Phase 1
Completed	Effects of Intermittent Fasting on Polycystic Ovary Syndrome (PCOS) Compared to Standard Treatment NCT06031753	Instituto Superior de Investigación en Estética Médica, Nutrición y Anti-Envejecimiento	N/A
Completed	Eosinophils in Human Adipose Tissue NCT04898400	Mayo Clinic	N/A
Completed	Efficacy of Lyophilized Dried Cornus Mas L. on Anthropometric and Biochemical Parameters in Insulin Resistance NCT05292300	Marmara University	N/A
Completed	Nutraceutical Composition Containing Natural Products Derivatives on the Modulation of the Endocrine Neuroimmu NCT04810572	University of Sao Paulo General Hospital	N/A
Unknown	Time-restricted Eating to Improve Metabolic Abnormalities in Polycystic Ovarian Syndrome NCT05126199	Ruairí Floyd	N/A
Unknown	Mechanisms Behind Severe Insulin Resistance During Pregnancy in Women With Glucose Metabolic Disorders (SIR-ME NCT04924504	University of Aarhus	—
Completed	Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics NCT04392284	University of Alabama at Birmingham	N/A
Completed	Effects of High-Intensity Interval Training Exercise in Adolescents With Hepatosteatosis NCT04342390	Arkansas Children's Hospital Research Institute	N/A
Completed	The Effect of a Multistrain Probiotic on Metformin Tolerance and Efficacy With Microbiota and Stool Metabolome NCT06092060	Poznan University of Physical Education	N/A
Terminated	The Effect of Mobile Health-based Exercise on Hepatocellular Carcinoma Patients With Insulin Resistance NCT04649671	Samsung Medical Center	N/A
Completed	Ketogenic Diet in PCOS With Obesity and Insulin Resistance NCT04801173	IRCCS Azienda Ospedaliero-Universitaria di Bologna	N/A
Recruiting	Exercise Effects on Adipose Tissue Structure and Function NCT04812314	University of Michigan	N/A
Completed	Probiotic Supplementation and Pancreatic β-Cell Function in Type 2 Diabetes NCT05765292	Bogomolets National Medical University	N/A
Terminated	Insulin and Muscle Fat Metabolism NCT04759872	Oregon State University	N/A
Completed	Serum Pro-Diabetes Inflammation Biomarkers in Patients With Apical Periodontitis. NCT04824209	University of Turin, Italy	—
Completed	Fiber and Insulin Sensitivity NCT04714944	Maastricht University Medical Center	N/A
Completed	Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Con NCT04529473	Atlantia Food Clinical Trials	N/A
Unknown	Insulin Resistance and Severity of Coronary Artery Disease NCT05215821	Sohag University	—
Completed	Exercise to Restore 24h Rhythms in Metabolism NCT04565418	Maastricht University	N/A
Unknown	Hormonal and Inflammatory Changes During Pregnancy in Women With Glucose Metabolic Disorders. NCT04617405	University of Aarhus	—
Completed	Effects of Hepatic Ultrasound on Metabolic Homeostasis NCT04622683	Yale University	N/A
Completed	Aerobic Exercise With Diet Induces Hormonal, Metabolic, and Psychological Changes NCT05136742	Cairo University	N/A
Withdrawn	Insulin Resistance Following ADT for Prostate CA NCT04658849	St. Louis University	EARLY_Phase 1
Completed	Effects of a Plant-Based Diet on Insulin Requirements and Obesity Markers in Obese Adults With T2DM NCT04048642	University of Rochester	N/A
Completed	Carbohydrate-induced Resilience of the Gut Microbiome After Antibiotics Use NCT04561284	Maastricht University Medical Center	N/A
Completed	Demonstration of the Prebiotic-like Effects of Camu-camu Consumption Against Obesity-related Disorders in Huma NCT04130321	Laval University	N/A
Unknown	Validation of a 13C Glucose Breath Test Compared With the Euglycaemic Clamp Test NCT04623320	University Hospital, Antwerp	—
Unknown	The S.L.I.M.M.S. Procedure for Severe Clinical Obesity NCT04592601	The N.E.W. Program	N/A
Completed	Effects of Obesity and Intensity of Exercise on Ghrelin Levels NCT04581980	University of Virginia	N/A
Completed	eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk NCT04437485	Indiana University	Phase 2
Recruiting	Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma NCT05208671	University of Oklahoma	N/A
Completed	Kelulut Honey as an Alternate Source of Carbo-Loading in Abdominal Surgery Involving the Digestive System NCT04438590	Universiti Sains Malaysia	N/A
Completed	Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle NCT04558190	University of Copenhagen	N/A
Completed	Molecular Mechanisms of Exercise Benefits to Insulin Resistant People NCT04158375	Mayo Clinic	N/A
Completed	The Effect of 12-week Circuit Training on Insulin Sensitivity and Endothelial Function in Women With Insulin R NCT04528693	Poznan University of Physical Education	N/A
Completed	The Effects of Water-only Fasting and Refeeding on Body Composition NCT04514146	TrueNorth Health Foundation	—
Completed	Impact of Insulin on Sympathetic Nervous System-mediated Peripheral Vasoconstriction NCT05244694	University of Missouri-Columbia	EARLY_Phase 1
Withdrawn	Effect of Neuromuscular Electrostimulation on Sympathetic Nerve Activity in Patients With Type 2 Diabetes (ELE NCT02171351	University Hospital, Caen	N/A
Recruiting	Effect of Interval Aerobic Training and Mindfulness Breathing on Hormonal, Metabolic, and Tumor Markers in Pos NCT04471506	Cairo University	N/A
Completed	Antecedent Metabolic Health and Metformin Aging Study NCT04264897	Oklahoma Medical Research Foundation	Phase 3
Terminated	Effect of Serum LDL Cholesterol Concentration on Pancreatic Insulin Secretion NCT04314167	University Hospital Tuebingen	N/A
Completed	Effectiveness of Low Level Laser Therapy on Insulin Resistance and Inflammatory Biomarkers NCT04477109	Cairo University	N/A
Completed	Ertugliflozin: Cardioprotective Effects on Epicardial Fat NCT04167761	Stanford University	EARLY_Phase 1
Completed	Impact of Poplar Propolis on Metabolic Disturbances of Insulin Resistance NCT05717881	Aix Marseille Université	N/A
Completed	Improving Insulin Sensitivity by Non-invasive Brain Stimulation NCT04420650	University Hospital Tuebingen	N/A
Completed	Walking Before or After Breakfast - Which is Better to Improve Health in Overweight Individuals? NCT06240663	Liverpool John Moores University	N/A
Withdrawn	Improving Insulin Resistance in Gynecological Cancer Patients NCT04139694	Woman's	N/A
Completed	Insulin Resistance, Sarcopenia and Plasma BAIBA Levels NCT04309201	Tungs' Taichung Metroharbour Hospital	—
Unknown	Nesfatin-1 Level in Patients With Type 2 Diabetes, Insulin Resistance and Obesity NCT04298515	Istanbul Medeniyet University	N/A
Terminated	Exercise in Adolescents With Insulin Resistance NCT04154865	University of Wisconsin, Madison	N/A
Unknown	Studying the Effect of Mediterranean Diet on Insulin Resistance Among Obese Children and Adolescents NCT04313452	University of Jordan	N/A
Completed	Impact of Digital Therapeutic on Metabolic Parameters NCT04573296	Vitadio s.r.o.	N/A
Unknown	Insulin Resistance in Stress-metabolic Medical Patients NCT04239937	Slagelse Hospital	—
Completed	Human Milk Oligossaccharide and Acetate Production in Vivo NCT04795804	Maastricht University Medical Center	N/A
Withdrawn	Effects of Omega-3 Fatty Acid Supplementation and Physical Training on Metabolic Health NCT06533891	University of Arizona	N/A
Completed	Inositol Supplementation to Treat PCOS (INSUPP-PCOS) NCT03864068	Milton S. Hershey Medical Center	Phase 2
Unknown	N-acetyl-cysteine and Carbohydrate Metabolism Disorder in Obese Women NCT03902327	Poznan University of Life Sciences	N/A
Completed	Hepassocin Levels in Patients With Polycystic Ovary Syndrome NCT04369248	Fatma ketenci gencer	—
Completed	Low Dose Fat-Induced Insulin Resistance NCT03479671	University of Pennsylvania	EARLY_Phase 1
Completed	Prevention With Oleanolic Acid of Insulin Resistance NCT05049304	Universidad de Granada	N/A
Completed	Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity NCT04195061	Massachusetts General Hospital	—
Terminated	CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia NCT04452396	Barts & The London NHS Trust	N/A
Terminated	The Effect of Curcumin on the Development of Prednisolone-induced Hepatic Insulin Resistance NCT04315350	University Hospital, Gentofte, Copenhagen	N/A
Enrolling By Invitation	Genetic Pathways Leading to Fatty Liver and Atherogenic Dyslipidemia NCT04209816	Marja-Riitta Taskinen	—
Recruiting	Pregnancy Outcomes: Effects of Metformin Study (POEM Study) NCT02947503	Bethesda Diabetes Research Center	Phase 3
Completed	Effectiveness of Antidiabetic Treatment Applied in Childhood Obesity NCT06266598	HÜMEYRA ACIKAN	Phase 4
Completed	Effectiveness of Cinnamon on Insulin Resistance ( ECIRCCOS ) December 1, 2019 NCT04476160	Coordinación de Investigación en Salud, Mexico	N/A
Unknown	Improving Insulin Sensitivity by Non-invasive Brain Stimulation in Persons With Insulin Resistance NCT04052399	University Hospital Tuebingen	N/A
Unknown	Evaluation of Intra-Abdominal Fat Extraction Using HydraSolve T2D™ in Obese Subjects With Type 2 Diabetes NCT03953963	Medality Medical	N/A
Active Not Recruiting	Precision Nutrition and Metabolic Function NCT04131166	Washington University School of Medicine	N/A
Terminated	Association of Insulin Resistance and FGF21 on Cardiac Function in Pediatric Dilated Cardiomyopathy NCT04222101	Le Bonheur Children's Hospital	N/A
Completed	Insulin Resistance in Adolescents NCT04089332	University of Wisconsin, Madison	N/A
Completed	The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune R NCT05558488	Katarzyna Siedzik	N/A
Completed	Synbiotic Therapy on Intestinal Microbiota and Insulin Resistance in Obesity NCT04642482	Hasanuddin University	Phase 4
Completed	Investigation of Urinary Biomarkers for the Diagnosis of Insulin Resistance NCT04010903	University Hospital, Montpellier	N/A
Completed	Fructose: Substrate, Stimulus, or Both? NCT04168372	Touro University, California	N/A
Completed	Potato Research for Enhancing Metabolic Outcomes NCT04203238	Pennington Biomedical Research Center	N/A
Completed	Effects of Maple Syrup on Gut Microbiota Diversity and Metabolic Syndrome NCT04117802	Laval University	N/A
Unknown	Effect of Low Dose Combination of Linagliptin + Metformin to Prevent Diabetes NCT04134650	Universidad de Guanajuato	Phase 3
Unknown	Effect of Empagliflozin + Linagliptin + Metformin + Lifestyle in Patients With Prediabetes NCT04131582	Universidad de Guanajuato	Phase 3
Unknown	Effect of Proprietary Botanical Blend on Glycemic Control and Post-prandial Carbohydrate Absorption NCT03897517	Plexus Worldwide	N/A
Completed	Mitochondrial Remodeling After Exercise NCT04103424	Oregon State University	N/A
Completed	Metformin Use to Improve Pregnancy Outcome in Women With Type 1 Diabetes. NCT03765359	Tampere University Hospital	Phase 4
Unknown	Secular Trends in the Prevalence of Cardiometabolic Risk Factors Among Teenage School Children in Urban South NCT04015726	India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals	—
Active Not Recruiting	Role of Metformin on Muscle Health of Older Adults NCT03107884	University of Utah	EARLY_Phase 1
Completed	Mitochondrial Methylation in Type 2 Diabetes NCT04126551	University of Arizona	—
Completed	Hypoxic Exercise and Glucose Metabolism NCT04280991	Maastricht University Medical Center	N/A
Completed	ENAC Blockade and Arterial Stiffness NCT03837626	University of Missouri-Columbia	Phase 2 / Phase 3
Completed	Effect of Lifestyle and/or Metformin Intervention on Pregnancy Outcome, A Pilot Randomized Controlled Trial NCT03898037	Reproductive & Genetic Hospital of CITIC-Xiangya	N/A
Unknown	Evaluation of a Combination of a Plant Extract and a Probiotic on Glucidic Metabolism in Women With PCOS and H NCT04029805	Biosearch S.A.	Phase 1 / Phase 2
Completed	Wheat Germ Supplementation Will Improve Markers of Gut Health, Inflammation, and Insulin Resistance in Overwei NCT03989882	Oklahoma State University	N/A
Unknown	The Influence of Overfeeding Different Macronutrients on Whole-body Insulin Sensitivity NCT03863431	Loughborough University	N/A
Unknown	Extra Virgin Olive Oil on Glycemic Control ,Insulin Resistance and Insulin Secretion NCT03891927	Assiut University	N/A
Completed	De Novo Lipogenesis and Insulin Sensitivity in Obese NCT04260542	Charles University, Czech Republic	N/A
Completed	Immunometabolism in Pediatric Obesity NCT03960333	Arkansas Children's Hospital Research Institute	—
Completed	Fasting for Brain and Heart Health (FBHH) NCT04507516	TrueNorth Health Foundation	—
Unknown	Prevalence of NAFLD and Correlation With Its Main Risk Factors Among Egyptian NCT04081571	Cairo University	—

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