NCT04168372

Fructose: Substrate, Stimulus, or Both?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: Touro University, California · Academic / Other
• Sex: All
• Age: 20 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This objective of this study is to use sensitive methodology under controlled conditions to investigate the mechanisms by which fructose consumption contributes to excess fatty acid synthesis and elevations in blood glucose levels following consumption of meals containing fructose.

Conditions

• Insulin Resistance
• Insulin Sensitivity
• Pre Diabetes

Interventions

Type	Name	Description
OTHER	High fructose, fructose labeled meal	Liquid meal containing high fructose (16% of energy), labeled with 2-13C fructose
OTHER	High fructose, pyruvate labeled meal	Liquid meal containing high fructose (16% of energy), labeled with 2-13C pyruvate
OTHER	Low fructose, fructose labeled meal	Liquid meals containing low fructose (6% of energy), labeled with 2-13C fructose
OTHER	Low fructose, pyruvate labeled meal	Liquid meal containing low fructose (6% of energy), labeled with 2-13C pyruvate

Timeline

• Start date: 2019-09-15
• Primary completion: 2024-11-20
• Completion: 2024-11-20
• First posted: 2019-11-19
• Last updated: 2025-04-10

Locations

1 site across 1 country: United States