| Withdrawn | Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance NCT04062890 | University of Arizona | Phase 2 |
| Not Yet Recruiting | The Importance of Insulin Action in the Brain for the Immune System During Physical Activity-Overweight NCT07466173 | University of Ulm | N/A |
| Recruiting | Effect of Physiologic Insulin Administration on Insulin Sensitivity and Cognition NCT07265323 | Pennington Biomedical Research Center | N/A |
| Recruiting | The Effect of Colchicine, on Insulin Sensitivity in Individuals With Type 1 Diabetes and Systemic Low-grade In NCT07247734 | Asger Lund, MD | Phase 2 |
| Not Yet Recruiting | Insulin Sensitivity and Testosterone Response to Aerobic Exercise Versus Added Sugar Elimination in Polycystic NCT07139275 | Cairo University | N/A |
| Recruiting | Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial NCT06138821 | Pichamol Jirapinyo, MD, MPH | N/A |
| Recruiting | A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participan NCT06982859 | Eli Lilly and Company | Phase 1 |
| Recruiting | Evaluation of Molecular Hydrogen Supplementation to Enhance the Efficacy of Weight Loss Retreat in Overweight NCT06961110 | Palacky University | N/A |
| Recruiting | Physical Activity and Insulin Sensitivity Dynamics NCT06776094 | University of Copenhagen | N/A |
| Recruiting | Evaluating the Efficacy of Topical Insulin for the Restoration of Ocular Surface Interface in Dry Eye Disease. NCT06939959 | Khyber Teaching Hospital | Phase 4 |
| Active Not Recruiting | Aging Resilience Through Microbiota Optimization and Regulation NCT06649981 | Gonzalo Jorquera, PhD | Phase 1 |
| Active Not Recruiting | The Importance of Insulin Action in the Brain for the Immune System During Physical Activity NCT06552130 | University of Ulm | N/A |
| Terminated | Metabolic Adaptations to High-fat Diet NCT06537401 | George Washington University | N/A |
| Recruiting | Effect of GLP1 Receptor Agonist on Brain Insulin Responsiveness NCT06487832 | University Hospital Tuebingen | N/A |
| Completed | Effects of Fasted- Versus Fed-exercise on Metabolic Health in Physically Active Adults NCT06949709 | National Taiwan Normal University | N/A |
| Recruiting | Effect of Pulsatile Hormone Administration on Insulin Action NCT06216665 | Pennington Biomedical Research Center | N/A |
| Recruiting | Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night NCT06550115 | Colorado State University | N/A |
| Recruiting | Effect of Sleep Extension on Ceramides in People with Overweight and Obesity NCT06180837 | University of Utah | N/A |
| Recruiting | Postprandial Metabolome and Metabolic Flexibility NCT06878781 | Instituto Nacional de Medicina Genomica | N/A |
| Recruiting | Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling NCT06129110 | University of Colorado, Denver | N/A |
| Recruiting | Acute Microbial Switch NCT05764200 | Maastricht University Medical Center | N/A |
| Recruiting | The Acute T-Rex (Timing of Resistance Exercise) Study NCT06366399 | University of Utah | N/A |
| Recruiting | Mechanisms of Ultrasound Neuromodulation Effects in Diabetes NCT06042517 | Yale University | N/A |
| Completed | Saccharin and Acesulfame Potassium Consumption and Glucose Homeostasis in Older Adults With Prediabetes NCT05441982 | Virginia Polytechnic Institute and State University | N/A |
| Recruiting | The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time) NCT05992688 | Arkansas Children's Hospital Research Institute | N/A |
| Completed | Blood Donation Could Improve Insulin Sensitivity NCT05791968 | University of Castilla-La Mancha | N/A |
| Completed | Metabolic Health Improvement Program: Effects of a Workplace Sugary Beverages Sales Ban and Motivational Couns NCT05972109 | University of California, San Francisco | N/A |
| Recruiting | Metabolic Adaptations to Weight Loss With and Without Exercise NCT05806801 | University of Michigan | N/A |
| Unknown | Effect of Nocturnal Parenteral Nutrition on Bone Turnover and Energy Metabolism NCT05868785 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Recruiting | Circadian Intervention to Improve Cardiometabolic Health NCT05943626 | University of Utah | N/A |
| Recruiting | Obesity, Insulin Resistance, and PASC: Persistent SARS-CoV-2 NCT05833217 | Stanford University | N/A |
| Recruiting | Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes NCT05337098 | Virginia Polytechnic Institute and State University | N/A |
| Completed | Ultra-processed Food Consumption, Gut Microbiota, and Glucose Homeostasis NCT05358171 | Virginia Polytechnic Institute and State University | N/A |
| Completed | Exogenous Ketosis During Bed Rest in Older Adults NCT05679596 | McGill University | N/A |
| Completed | Lifestyle Intervention for Improving Insulin Resistance and Concern for Health NCT05649176 | Pennington Biomedical Research Center | N/A |
| Completed | Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Type 2 Diabetes Patients (DELI_Diab Study) NCT05770076 | Bogomolets National Medical University | N/A |
| Recruiting | Predictors of Weight Loss and Metabolic Health After Bariatric Surgery NCT05987631 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Completed | Activity, Adiposity, and Appetite in Adolescents 2 Intervention NCT05443347 | Children's Mercy Hospital Kansas City | N/A |
| Active Not Recruiting | Understanding Dose Related Effects of Strawberry NCT06173765 | Clinical Nutrition Research Center, Illinois Institute of Technology | N/A |
| Unknown | Effect of Triticum Aestivum vs Placebo on Metabolic Profile Components and Insulin Sensitivity in Patients Wit NCT06501248 | Coordinación de Investigación en Salud, Mexico | Phase 3 |
| Recruiting | MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sen NCT05065372 | Kalie Tommerdahl | Phase 1 |
| Completed | Effect of Dairy Products on Insulin Resistance NCT05421390 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Completed | Sucralose and Glucose Metabolism in Young Healthy Adults NCT07194772 | University of Ottawa | N/A |
| Recruiting | mTOR as Mediator of Insulin Sensitivity Study NCT05233722 | University of Copenhagen | N/A |
| Active Not Recruiting | Energy Metabolism and Acute Effects of Protein Diets in Metabolically Obese Normal Weight Individuals NCT06802341 | Singapore Institute of Food and Biotechnology Innovation | N/A |
| Completed | Activity, Adiposity, and Appetite in Adolescents 2 NCT04028921 | Children's Mercy Hospital Kansas City | — |
| Completed | Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM NCT05093517 | The University of Texas Health Science Center at San Antonio | EARLY_Phase 1 |
| Recruiting | Countermeasures to Circadian Misalignment NCT04966351 | Colorado State University | N/A |
| Completed | Effect of Acute Bout of Exercise on Levels of PAHSA NCT05572905 | Lenka Rossmeislova | N/A |
| Unknown | Mechanisms Behind Severe Insulin Resistance During Pregnancy in Women With Glucose Metabolic Disorders (SIR-ME NCT04924504 | University of Aarhus | — |
| Completed | The Effects of Orchiectomy and Age on Vascular and Metabolic Health in Older Versus Younger Transgender Women NCT05195164 | University of Colorado, Denver | — |
| Recruiting | Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth NCT04596592 | University of Colorado, Denver | — |
| Unknown | Effects of Glucose Lowering Agents in South Asian Women With Impaired Glucose Tolerance or Impaired Fasting Gl NCT04662866 | Oslo University Hospital | Phase 2 |
| Completed | Development of a Novel Method to Measure Insulin Sensitivity in Humans: A Pilot Study NCT04774081 | Pennington Biomedical Research Center | — |
| Completed | Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Con NCT04529473 | Atlantia Food Clinical Trials | N/A |
| Unknown | Hormonal and Inflammatory Changes During Pregnancy in Women With Glucose Metabolic Disorders. NCT04617405 | University of Aarhus | — |
| Unknown | Effect of Prebiotics on Blood Glucose Management NCT04636489 | Sun Yat-sen University | N/A |
| Completed | Effects of Regular Activity on Physiology Between Recreational Athletes of Different Body Fatness NCT05154422 | Florida State University | — |
| Terminated | Nutritional Supplementation and Insulin Sensitivity NCT04239482 | Maastricht University Medical Center | N/A |
| Unknown | Effects of Snuff and/or Red Wine om Metabolic Rate NCT04547426 | University Hospital, Linkoeping | N/A |
| Completed | Antecedent Metabolic Health and Metformin Aging Study NCT04264897 | Oklahoma Medical Research Foundation | Phase 3 |
| Completed | Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity NCT04286451 | Pennington Biomedical Research Center | N/A |
| Withdrawn | Obstructive Sleep Apnea Treatment and Insulin Sensitivity in Pregnancy NCT04013399 | Barnes-Jewish Hospital | N/A |
| Active Not Recruiting | Pulses Consumption and Its Role in Managing Systemic Inflammation, Insulin Sensitivity and Gut Microbiome in H NCT04267705 | Clinical Nutrition Research Center, Illinois Institute of Technology | N/A |
| Unknown | Effects of Empagliflozin on Cardiac Microvasculature and Insulin Sensitivity in Subjects With Type 2 Diabetes NCT04203927 | University of Virginia | EARLY_Phase 1 |
| Completed | Low Dose Fat-Induced Insulin Resistance NCT03479671 | University of Pennsylvania | EARLY_Phase 1 |
| Terminated | A Study of a Low-Carbohydrate Diet to Improve Maternal Health After Childbirth NCT04045353 | The University of Texas Medical Branch, Galveston | N/A |
| Completed | Effectiveness of Cinnamon on Insulin Resistance ( ECIRCCOS ) December 1, 2019 NCT04476160 | Coordinación de Investigación en Salud, Mexico | N/A |
| Completed | Exploring the Anti-inflammatory Properties of Cannabis and Their Relevance to Insulin Sensitivity NCT04114903 | University of Colorado, Boulder | — |
| Completed | Effect of Breathing Maneuvers on Peripheral Glucose Metabolism NCT04150627 | University Hospital Tuebingen | N/A |
| Completed | The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune R NCT05558488 | Katarzyna Siedzik | N/A |
| Completed | Metabolic Effects of Melatonin Treatment NCT03859934 | University of Aarhus | Phase 1 |
| Unknown | The Effect of Sitting and Moderate Exercise on Plasma Insulin and Glucose Responses to an Oral Glucose Toleran NCT04195165 | University of Texas at Austin | N/A |
| Completed | Fructose: Substrate, Stimulus, or Both? NCT04168372 | Touro University, California | N/A |
| Withdrawn | Insulin Signaling in Skeletal Muscle NCT03452267 | Wayne State University | Phase 2 / Phase 3 |
| Completed | Effect of Phosphorus Additives on the Metabolome in Healthy Adults NCT03841786 | University of Alabama at Birmingham | N/A |
| Completed | Pulse-based Foods for Alleviation of Negative Consequences of Sedentary Behaviour NCT03941704 | University of Saskatchewan | N/A |
| Completed | "Effect of Central Insulin Administration on Whole-body Insulin Sensitivity in Women" NCT03929419 | University Hospital Tuebingen | N/A |
| Completed | Effects of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles NCT04066283 | University of Colorado, Denver | — |
| Terminated | Preoperative Oral Carbohydrate Drink for Elective Cesarean Delivery and the Effect on Insulin Sensitivity NCT03494868 | Mayo Clinic | N/A |
| Completed | Effect of Hyperglycemia on Microvascular Perfusion in Healthy Adults NCT03520569 | University of Virginia | EARLY_Phase 1 |
| Terminated | Investigation of the Effects of Sedentary Behaviour and Moderate Exercise on Glucose Tolerance and Insulin Sen NCT03827239 | University of Prince Edward Island | N/A |
| Completed | Bisphenol A and Muscle Insulin Sensitivity NCT03771066 | California Polytechnic State University-San Luis Obispo | N/A |
| Completed | A Randomized, Crossover Study to Assess the Effects of Dietary Fiber-containing Bars on Glucose and Insulin Re NCT03796286 | Midwest Center for Metabolic and Cardiovascular Research | N/A |
| Completed | Smectite Gel and Probiotic for Obesity and Insulin Resistance NCT04293731 | Bogomolets National Medical University | N/A |
| Active Not Recruiting | Impact of Sleep Extension in Adolescents NCT03500458 | University of Colorado, Denver | N/A |
| Completed | Effects of Potato Resistant Starch Intake on Insulin Sensitivity, Related Metabolic Markers and Satiety NCT03689738 | Midwest Center for Metabolic and Cardiovascular Research | N/A |
| Completed | Ischemia-reperfusion Exercise Study NCT04872426 | University of Copenhagen | N/A |
| Completed | The Metabolic Effects of Cynara Supplementation in Overweight and Obese Class I Subjects With Newly Detected I NCT04616404 | Azienda di Servizi alla Persona di Pavia | N/A |
| Completed | Nutrition, Body Composition, and Sleep NCT03603041 | University of Arkansas, Fayetteville | N/A |
| Completed | Copenhagen, Boston, Sydney NCT04178603 | University of Copenhagen | N/A |
| Completed | Acute and Chronic Metabolic Flexibility in Individuals Living With Obesity: The i-FLEX Study NCT03527446 | University of New Brunswick | N/A |
| Completed | Seaweed Extract Supplementation and Metabolic Biomarkers NCT03853343 | BioAtlantis Ltd. | N/A |
| Completed | Orange Juice And Sugar Intervention Study NCT03527277 | University of California, Davis | N/A |
| Completed | Comparing the Effects of Different Types of Exercise on Glucose Handling NCT06217679 | University of Waterloo | N/A |
| Completed | Proof of Concept ELectro-Stimulation of Muscles to resolVe Insulin Resistance in NASH NCT03490370 | NHS Tayside | N/A |
| Completed | Effect of Physiologic Hyperglucogonemia on Adipocyte Metabolism NCT04300049 | The University of Texas Health Science Center at San Antonio | EARLY_Phase 1 |
| Completed | Effect of Probiotic Co-administration With Omega-3 Fatty Acids on Obesity Parameters and Insulin Resistance NCT04201938 | Bogomolets National Medical University | N/A |
| Completed | Metabolic and Muscular Adaptations During Inactivity in 3 Days of Bed-rest NCT03495128 | University of Nottingham | N/A |
| Completed | Mediterranean Style Diet and Low Glycemic Responses NCT03410719 | Purdue University | N/A |
| Completed | The Role of TBC1D4 in Exercise- and Insulin-induced Glucose Metabolism in Human Skeletal Muscle NCT04170972 | University of Copenhagen | N/A |
| Completed | Depression & Insulin Sensitivity in Adolescents NCT03263351 | Colorado State University | N/A |
| Terminated | Resistance Training and Cardiometabolic Health NCT03325933 | Arizona State University | N/A |
| Completed | Evaluation of New Beverages Rich in Bioactive Compounds for the Modulation of Energetic Metabolism in Overweig NCT04016337 | Universidad Católica San Antonio de Murcia | N/A |
| Completed | Determinants of Liver Fat Composition NCT03211299 | Maastricht University Medical Center | — |
| Enrolling By Invitation | Adaptive Immune Response in Visceral and Subcutaneous Fat: Role in Human Insulin Resistance NCT04708535 | Stanford University | — |
| Unknown | The Effect of Laparoscopic Sleeve Gastrectomy on Insulin Secretion Pattern in Morbidly Obese Patients With Aca NCT05529563 | Shen Qu | — |
| Completed | Myocellular Signalling in Skeletal Muscle NCT03203317 | University of Copenhagen | N/A |
| Unknown | Effects of Progressive Negative Energy Balance on Glucose Tolerance, Insulin Sensitivity, and Beta-cell Functi NCT03264001 | Singapore Institute of Food and Biotechnology Innovation | N/A |
| Unknown | The Potential of Carnosine Supplementation in Reducing the Cardiometabolic Risk NCT02686996 | Monash University | N/A |
| Completed | Effect of Yakult Ingestion on Diet-induced Insulin Resistance in Humans NCT03037918 | Loughborough University | N/A |
| Unknown | Effect of Camel Milk on Insulin and Incretin Response NCT03725969 | Imperial College London Diabetes Centre | N/A |
| Withdrawn | Racial Differences in Vagal Control of Glucose Homeostasis, Chronic Study NCT03014323 | Vanderbilt University Medical Center | Phase 1 |
| Completed | Dairy Products, Diabetes and Genetics NCT02961179 | CHU de Quebec-Universite Laval | N/A |
| Completed | Exercise and Insulin Signaling in Human Skeletal Muscle NCT02987491 | Oregon State University | N/A |
| Completed | Glucose Monitoring During Threatening Preterm Birth in Patients With and Without Gestational Diabetes Mellitus NCT03007186 | Medical University of Vienna | — |
| Suspended | Exercise Intervention for the Prevention of Prediabetes in Overweight Chinese NCT03240978 | The University of Hong Kong | N/A |
| Completed | Mitochondrial Function in Circulating Cells and Muscle Tissue NCT02700698 | University of Arkansas | — |
| Completed | The Acute Impact of Sit-stand Desks on Post-meal Blood Sugar Levels NCT02913079 | University of Prince Edward Island | N/A |
| Completed | Study of HIV-Infected and Uninfected Pregnant Woman/Child Dyads in Gaborone, Botswana NCT03088410 | Ann & Robert H Lurie Children's Hospital of Chicago | Phase 4 |
| Unknown | Effect of Consumption of Non Caloric Sweeteners and Insulin Sensibility NCT02890108 | Instituto de Nutrición y Tecnología de los Alimentos | N/A |
| Completed | Insulin Sensitivity, Glucose - and Fat Metabolism in Patients With Psoriasis NCT02978001 | University Hospital, Gentofte, Copenhagen | — |
| Unknown | Improving Glucose and Lipid Metabolism Through Caloric Restriction Using Diet or Surgery (CRUDOS) NCT02988011 | Uppsala University | N/A |
| Unknown | Persea Americana for Total Health (PATH ) Study NCT02740439 | University of Illinois at Urbana-Champaign | N/A |
| Completed | SUCCEED - Soroka Utility for Counting Carbs Easily and Effectively for Diabetes NCT04132128 | Soroka University Medical Center | N/A |
| Completed | Mood and Excess Weight Gain in Adolescent Pregnancy NCT03086161 | Colorado State University | N/A |
| Completed | The Influence of Sampling Site When Assessing Glucose Tolerance or Insulin Sensitivity With Oral Glucose Inges NCT02852044 | University of Bath | N/A |
| Completed | Palmitoleic Isomer Study NCT02311790 | Tufts University | N/A |
| Completed | Supervised Exercise-training in Children With Insulin Resistance or Healthy Metabolic Profile NCT03003754 | Universidad Santo Tomas | N/A |
| Completed | Glycemic and Hormone Responses After the Intake of Four Types of Bread. NCT02653677 | University of Turin, Italy | N/A |
| Unknown | Vitamin K and Glucose Metabolism in Adults at Risk for Diabetes (Vita-K 'n' Adults Study) NCT02366481 | Augusta University | N/A |
| Terminated | The Influence of Different Hydrocortisone Replacement Doses on the Partitioning and Flexibility of Ectopic Lip NCT02360046 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | The Role of TLR4 on Lipid-induced Insulin Resistance NCT02321111 | The University of Texas Health Science Center at San Antonio | Phase 2 |
| Terminated | The Effect of TLR4 Inhibition in Obese and Type 2 Diabetic Subjects NCT02267317 | The University of Texas Health Science Center at San Antonio | Phase 2 |
| Completed | Sugar-sweetened Beverages Influence Benefits of Exercise in Overweight Adults NCT03576703 | Montana State University | N/A |
| Completed | Bromocriptine and Insulin Sensitivity NCT02428946 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | The Effect of 6 Weeks Saturated and Polyunsaturated High-Fat Diets on Insulin Sensitivity and Health Parameter NCT03561363 | University of Copenhagen | N/A |
| Completed | Does Hyperbaric Oxygen Therapy Lead to a Sustained Increase in Insulin Sensitivity? NCT02136615 | University of Adelaide | — |
| Completed | The Effect of Breaking Prolonged Sitting on Adipose Tissue and Metabolism NCT02870088 | University of Bath | N/A |
| Completed | Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic Syndrom NCT02633488 | University of Virginia | N/A |
| Completed | Comparative the Effect of Metformin and Acupuncture on Weight Loss and Insulin Sensitivity NCT02438540 | Amir Firouzjaei | N/A |
| Completed | A Natural History of Perioperative Metabolism NCT04396964 | University of Vermont Medical Center | — |
| Completed | Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2) NCT02127125 | The University of Texas Health Science Center at San Antonio | Phase 2 |
| Completed | Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim 1) NCT02124759 | The University of Texas Health Science Center at San Antonio | Phase 2 |
| Completed | Modulation of Insulin Sensitivity by Betaine Upregulation of FGF21 NCT02118142 | UNC Nutrition Research Institute | N/A |
| Completed | Race Adiposity Interactions Regulate Mechanisms Determining Insulin Sensitivity NCT03043235 | University of Alabama at Birmingham | — |
| Unknown | Milk Fat Intake and Metabolic Health Markers NCT02659748 | University of Vermont Medical Center | N/A |
| Completed | How is Glycogen Supercompensation Regulated in Human Skeletal Muscle NCT03458741 | University of Copenhagen | N/A |
| Unknown | Vitamin K and Glucose Metabolism in Children at Risk for Diabetes (Vita-K 'n' Kids Study) NCT01972113 | Augusta University | N/A |
| Terminated | Insulin Resistance Before and During Pregnancy in Women With Polycystic Ovary Syndrome NCT01475565 | Virginia Commonwealth University | — |
| Completed | Influence of Brain Insulin Sensitivity on Peripheral Insulin Sensitivity NCT01847456 | University Hospital Tuebingen | N/A |
| Completed | Investigating Inter-individual Variability in Glycemic and Insulin Responses NCT01804738 | Institute for Human Development and Potential (IHDP), Singapore | N/A |
| Completed | The Effects of Sea Buckthorn and Strawberry on Postprandial Glycaemia, Insulinemia and Appetite NCT02412995 | University of Copenhagen | EARLY_Phase 1 |
| Completed | Effect of Low-carbohydrate/High-fat Diet on Glucose Tolerance and Lipid Profile in Lean, Healthy Women NCT02005224 | Atlantis Medical University College | N/A |
| Completed | Regulation of Branched-chain Amino Acid Metabolism in Pre-Diabetes NCT01786941 | Duke University | N/A |
| Completed | METAPREDICT: Developing Predictors of the Health Benefits of Exercise for Individuals NCT01920659 | Loughborough University | N/A |
| Completed | The Effect of Lowered Physical Activity on Insulin Sensitivity and Lipid and Glucose Metabolism NCT01576250 | Maastricht University Medical Center | N/A |
| Completed | Acute Effects of an Oral Fat Load on Skeletal Muscle and Hepatic Insulin Sensitivity NCT01736202 | German Diabetes Center | Phase 4 |
| Completed | Effects of Dietary Fats on Cardiovascular Health and Insulin Sensitivity in Subjects With Abdominal Obesity NCT01665482 | Malaysia Palm Oil Board | N/A |
| Completed | Insulin Variance Throughout the Day NCT01546545 | Pennington Biomedical Research Center | — |
| Completed | Insulin Sensitivity and Beta Cell Function After Carbohydrate Loading in Hip Replacement Surgery NCT01774084 | Karolinska Institutet | Phase 4 |
| Completed | The Effect of Brown Adipose Tissue Activation on Insulin Sensitivity in Humans NCT01791114 | Rutgers University | N/A |
| Completed | Oral Contraceptives, Insulin Resistance and Cardiovascular Risk Profile in Pre-Menopausal Women NCT01475513 | Virginia Commonwealth University | Phase 4 |
| Completed | Effect of Meal Frequency on Glycemic Control of People at High Risk or Diagnosed With Diabetes NCT02248272 | Meropi Kontogianni | N/A |
| Completed | Effects of Sugar Sweetened Beverage on Metabolic Health in Male and Female Adolescents NCT02058914 | University of Missouri-Columbia | N/A |
| Completed | The Effect of Dietary Fat Load and Physical Exercise on the Flexibility and Partitioning of Ectopic Lipids. NCT01467193 | Insel Gruppe AG, University Hospital Bern | — |
| Completed | Long-term Investigation of Resveratrol in Obesity NCT01412645 | University of Aarhus | N/A |
| Completed | Effects of Different Doses of Pinitol on Carbohydrate Metabolism Parameters in Healthy Subjects NCT01738763 | University of Valencia | N/A |
| Completed | Association Between Vitamin D and Inflammation and Diabetes Risk in Morbidly Obese Pre-Menopausal Women NCT02169050 | University of Illinois at Chicago | — |
| Completed | Study of Dapagliflozin on Mitochondrial Dysfunction and Impaired Insulin Signaling/Action NCT01439854 | The University of Texas Health Science Center at San Antonio | N/A |
| Completed | Effect of Vitamin D Replacement on Insulin Sensitivity NCT01268111 | Texas Tech University Health Sciences Center | Phase 1 |
| Completed | The Vascular and Metabolic Effects of Sunitinib in Patients With Metastatic Renal Cell Carcinoma NCT01227213 | Radboud University Medical Center | — |
| Completed | The Effects of a Jump Rope Exercise Program on Body Composition and Self-efficacy in Obese Adolescent Girls NCT03898518 | Pusan National University | N/A |
| Completed | Bariatric Surgery and Weight Loss on Energy Metabolism and Insulin Sensitivity NCT00936130 | Pennington Biomedical Research Center | — |
| Completed | Obesity, Sleep Apnea, and Insulin Resistance NCT02192684 | Stanford University | N/A |
| Completed | Assessment of Cod Protein as an Insulin-sensitizing Agent in Women With Polycystic Ovary Syndrome. NCT01766557 | Laval University | N/A |
| Completed | Gene - Diet Interactions NCT01274091 | Marjukka Kolehmainen | N/A |
| Terminated | Assessment of Renin Inhibition on Insulin Sensitivity, Diastolic Function and Aortic Compliance NCT01252238 | Brigham and Women's Hospital | N/A |
| Unknown | Vaspin Levels Compared With Serum Insulin and Blood Glucose Levels in Neonates NCT01363622 | Zekai Tahir Burak Women's Health Research and Education Hospital | — |
| Completed | Vascular Function, Insulin Sensitivity, and Vitamin D NCT01041547 | University of Alabama at Birmingham | — |
| Completed | Vitamin D, Insulin Sensitivity, and Vascular Associations in Adolescents NCT01041365 | University of Alabama at Birmingham | — |
| Withdrawn | Calcium, Vitamin D and Metformin to Treat Insulin Resistance in Obese African American Adolescent Females NCT01107808 | University of Alabama at Birmingham | N/A |
| Completed | Implication of Metabolic and Genomic Modifications in Elderly Subjects NCT00951392 | Hospices Civils de Lyon | N/A |
| Completed | Nutritional Prevention of Diabetes Mellitus Type 2 NCT03231839 | University Hospital Tuebingen | N/A |
| Completed | Insulin Resistance and Substrate Metabolism After Acute Erythropoietin (EPO) Administration NCT00793767 | Aarhus University Hospital | N/A |
| Completed | Metabolic Syndrome and Gen-polymorphs Influence on Weightloss Among Children in Treatment for Overweight NCT00823277 | Holbaek Sygehus | — |
| Completed | Vitamin D AND Glucose Handling Evaluated by Glucose Clamp NCT00809744 | University Hospital of North Norway | Phase 2 |
| Completed | Comparing Soybean Oil-Based (Intralipid) With an Olive Oil-Based (ClinOleic) Lipid Emulsion on Healthy Volunte NCT02185729 | Emory University | Phase 2 / Phase 3 |
| Completed | The Effect of Endurance Training in Patients With Prostate Cancer NCT01584960 | Inge Holm | N/A |
| Completed | Assessment of Influence of Vitamin D on Insulin Secretion and Sensitivity in Obese Teenage Girls NCT00851396 | University of Alabama at Birmingham | — |
| Completed | Exercise and Inflammation in the Elderly NCT00753363 | VA Office of Research and Development | N/A |
| Completed | Physical Training Per se NCT01090869 | University of Copenhagen | N/A |
| Withdrawn | The Effect of Blueberries on Enhancing Insulin Sensitivity in Humans: A Pilot Study NCT01005420 | Pennington Biomedical Research Center | N/A |
| Completed | PED/PEA-15 Protein, PCOS, Obesity, Insulin Sensitivity Indexes, Metformin, Oral Contraceptives NCT00948402 | Federico II University | Phase 3 |
| Completed | Role of Angiotensin II in Insulin-induced Microvascular Activity NCT01024543 | Maastricht University Medical Center | N/A |
| Completed | Metabolic Effects of an 8 Week Niaspan Treatment in Patients With Abdominal Obesity and Mixed Dyslipidemia NCT01216956 | Centre de Recherche en Nutrition Humaine Rhone-Alpe | N/A |
| Completed | Effects of Different Surgical Methods to Treat Obesity NCT01785134 | Karolinska Institutet | N/A |
| Completed | Exercise and Diet in Type 2 Diabetic Women NCT00763074 | Eulji University Hospital | N/A |
| Completed | Acute Effects of Glucose Dependent Insulinotropic Polypeptide (GIP) on Subcutaneous Adipose Tissue NCT00774488 | German Institute of Human Nutrition | N/A |
| Terminated | Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS) NCT00682890 | Virginia Commonwealth University | Phase 4 |
| Completed | Insulin Resistance and Intramyocellular Lipid Content in Glucose Intolerant Subjects Receiving Rosiglitazone NCT00746174 | University of Texas Southwestern Medical Center | Phase 4 |
| Completed | Mechanism of Insulin-Resistant in Lean Non-Diabetics NCT00970099 | University of California, San Francisco | Phase 1 |
| Unknown | Glucose and Lipid Metabolism in Adolescents NCT00998855 | National Institutes of Health (NIH) | — |
| Completed | The Effect of Gemcabene on Insulin Sensitivity in Nondiabetic Subjects NCT02586168 | NeuroBo Pharmaceuticals Inc. | Phase 2 |
| Completed | Effects of Rosiglitazone and Metformin on Metabolism in Type 2 Diabetes NCT02526615 | Turku University Hospital | Phase 4 |
| Completed | Effect of Diacylglycerol Oil on Risk Factors of Type 2 Diabetes and Complicating Disease, and Mechanism NCT01802541 | Zhejiang University | N/A |