NCT04636489

Effect of Prebiotics on Blood Glucose Management

An Interventional Study for the Effects of Highland Barley β-glucan on the Management of Glucose Metabolism and Insulin Sensitivity

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 30 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This survey is designed to investigate the effect of highland barley β-glucan supplementation on the regulatory of blood glucose, gut microbiota and cardiovascular risk fators in subjects with hyperglycemia.

Detailed description

Highland barley β-glucan belongs to the group of prebiotics and has been found to be associated with multiple health benefits. However, its protective role in subjects with hyperglycemia are remain unclear. This study aims to examine the effect of 8-week prebiotics supplementation on glucose management in subjects with hyperglycemia. By understanding the mechanism by which prebiotics exert the beneficial effects, we can better control the rising prevalence of hyperglycemia, which is a major risk factor for cardiovascular diseases.

Conditions

• Hyperglycemia
• Insulin Sensitivity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Highland barley β-glucan dietary supplement	100 mL oral liquid mainly containing highland barley β-glucan once daily for 8 weeks
OTHER	Placebo controls	Placebo with a similar appearance and taste to highland barley β-glucan supplement

Timeline

• Start date: 2020-11-30
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2020-11-19
• Last updated: 2022-05-05

Locations

1 site across 1 country: China