NCT05529563

The Effect of Laparoscopic Sleeve Gastrectomy on Insulin Secretion Pattern in Morbidly Obese Patients With Acanthosis Nigricans

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 138 (estimated)
• Sponsor: Shen Qu · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Acanthosis nigricans (AN) is increasing in its prevalence and is the most prevalent cutaneous manifestation in individuals with obesity. Insulin resistance or hyperinsulinemia is the main pathophysiological mechanism of obesity-related AN. However, the effect of laparoscopic sleeve gastrectomy (LSG) on insulin secretion pattern in Chinese morbidly obese patients with AN is unknown. In these study, the investigators aimed to explore the insulin secretion patterns in Chinese morbidly obese patients with Acanthosis nigricans (AN) and their alterations after LSG.

Conditions

• Morbid Obesity
• Acanthosis Nigricans
• Insulin Resistance
• Insulin Sensitivity
• Bariatric Surgery Candidate

Interventions

Type	Name	Description
PROCEDURE	LSG	LSG

Timeline

• Start date: 2017-06-01
• Primary completion: 2022-10-01
• Completion: 2022-10-31
• First posted: 2022-09-07
• Last updated: 2022-09-07

Locations

1 site across 1 country: China