NCT04514146

The Effects of Water-only Fasting and Refeeding on Body Composition

A Pilot Study on the Effects of Water-only Fasting and Refeeding on Body Composition and Insulin Resistance

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 48 (actual)
• Sponsor: TrueNorth Health Foundation · Academic / Other
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: —

Summary

This observational pilot study will assess the effects of water-only fasting on body composition and insulin resistance

Detailed description

This pilot study will explore the effects of water-only fasting followed by an exclusively whole-plant-food diet free of added salt, oil, and sugar on body composition with a particular focus on visceral adipose tissue (VAT). The study will also extend a previous study assessing the effects of fasting and refeeding on Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) values and markers of cardiovascular health and inflammation by following participants for an additional 6 weeks.

Conditions

• Visceral Obesity
• Insulin Resistance

Interventions

Type	Name	Description
OTHER	Water-only fasting	In-patient water-only fasting for at least 10 days followed by at least 5 days of refeeding

Timeline

• Start date: 2020-08-15
• Primary completion: 2021-10-01
• Completion: 2021-10-01
• First posted: 2020-08-14
• Last updated: 2021-10-06

Locations

1 site across 1 country: United States