NCT07486557

Cistanche Deserticola Extract Combined With Aerobic Exercise Improves Body Composition, Insulin Resistance and Inflammation in Men With Central Obesity

Cistanche Deserticola Extract Combined With Aerobic Exercise Improves Body Composition, Insulin Resistance and Inflammation in Men With Central Obesity: a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 125 (actual)
• Sponsor: Beijing Sport University · Academic / Other
• Sex: Male
• Age: 50 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This is a randomized controlled trial to see if a combination of aerobic exercise and Cistanche deserticola extract can improve body composition, insulin resistance, and inflammation in men with central obesity. Participants will be randomly assigned to either an intervention group (18 weeks of supervised aerobic exercise plus daily Cistanche extract supplementation) or a control group (usual lifestyle advice). The investigators will measure changes in body fat percentage, muscle mass, blood sugar, insulin levels, and inflammatory markers before and after the 18-week intervention. The goal is to find a safe and effective way to help men with central obesity improve their metabolic health. Possible benefits include better body composition and improved insulin sensitivity. Potential risks are mild muscle soreness or digestive discomfort from the supplement.

Conditions

• Central Obesity
• Insulin Resistance
• Inflammation

Interventions

Type	Name	Description
BEHAVIORAL	Supervised Aerobic Exercise	Moderate-intensity aerobic exercise 3 times per week, 40 minutes per session, for 18 weeks, supervised by trained exercise professionals.
DIETARY_SUPPLEMENT	Cistanche deserticola Extract	Daily oral supplementation with standardized Cistanche deserticola extract for 18 weeks, administered as a capsule or powder.

Timeline

• Start date: 2025-06-01
• Primary completion: 2026-03-01
• Completion: 2026-03-01
• First posted: 2026-03-20
• Last updated: 2026-03-20

Locations

1 site across 1 country: China