Trials / Completed
CompletedNCT04714944
Fiber and Insulin Sensitivity
Gut Microbial Substrate Switch to Improve Metabolic Health
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 42 (actual)
- Sponsor
- Maastricht University Medical Center · Academic / Other
- Sex
- All
- Age
- 45 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
Based on previous research of the investigators group, the investigators hypothesize that slowly fermentable fibers with a high degree of polymerization that increase SCFA specifically in the distal colon are expected to have higher potential for influencing host metabolism and metabolic health by improving adipose tissue function, preventing lipid overflow and hepatic as well as skeletal muscle fat accumulation thereby improving insulin sensitivity. The objective of this randomized clinical trial is to test, whether the a dietary fiber product containing different physiological acting fibers reverses peripheral and hepatic insulin resistance in overweight/obese insulin resistant participants.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Placebo | Supplementation period 12 weeks |
| DIETARY_SUPPLEMENT | Whole fiber product | Supplementation period 12 weeks |
Timeline
- Start date
- 2021-02-05
- Primary completion
- 2023-03-29
- Completion
- 2023-03-29
- First posted
- 2021-01-20
- Last updated
- 2024-02-12
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT04714944. Inclusion in this directory is not an endorsement.