NCT06471569

Role of Aging and Individual Variation in Exercise Training Responsiveness

The Role of Aging and Individual Variation in Exercise Training Responsiveness

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 26 (estimated)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 60 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The primary purpose of this study is to assess the effects of aging on markers of physical reserve and exercise-induced adaptations in resilience in older adults who completed a structured exercise program within the last 15 years (Parent trial: STRRIDE-PD; NCT00962962). This feasibility pilot study will enroll up to 26 participants to complete a 6-month aerobic exercise intervention.

Conditions

• Prediabetic State
• Cardiovascular Diseases
• Insulin Resistance
• Obesity

Interventions

Type	Name	Description
BEHAVIORAL	Low/Mod	Aerobic exercise at 50% peak oxygen consumption for the number of weekly minutes prescribed in the original STRRIDE trial
BEHAVIORAL	High/Mod	Aerobic exercise at 50% peak oxygen consumption for the number of weekly minutes prescribed in the original STRRIDE trial
BEHAVIORAL	High/Vig	Aerobic exercise at 75% peak oxygen consumption for the number of weekly minutes prescribed in the original STRRIDE trial

Timeline

• Start date: 2025-04-02
• Primary completion: 2027-03-31
• Completion: 2027-03-31
• First posted: 2024-06-24
• Last updated: 2025-11-14

Locations

1 site across 1 country: United States